scholarly article | Q13442814 |
P356 | DOI | 10.1085/JGP.110.6.655 |
P953 | full work available online at | http://jgp.rupress.org/content/jgp/110/6/655.full.pdf |
https://europepmc.org/articles/PMC2229396 | ||
https://europepmc.org/articles/PMC2229396?pdf=render | ||
https://rupress.org/jgp/article-pdf/110/6/655/1729196/gp_7589.pdf | ||
P932 | PMC publication ID | 2229396 |
P698 | PubMed publication ID | 9382894 |
P5875 | ResearchGate publication ID | 13846931 |
P2093 | author name string | C. G. Nichols | |
S. Shyng | |||
P2860 | cites work | Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs. | Q42604432 |
Determination of the subunit stoichiometry of an inwardly rectifying potassium channel | Q46248253 | ||
A structural determinant of differential sensitivity of cloned inward rectifier K+ channels to intracellular spermine | Q49076429 | ||
Spermine and spermidine as gating molecules for inward rectifier K+ channels | Q49081382 | ||
Electrostatic tuning of Mg2+ affinity in an inward-rectifier K+ channel | Q49089411 | ||
Subunit stoichiometry of the pancreatic β-cell ATP-sensitive K+ channel | Q57591506 | ||
Nucleotide modulation of the activity of rat heart ATP-sensitive K+ channels in isolated membrane patches | Q69442188 | ||
Subunit-dependent assembly of inward-rectifier K+ channels | Q71764032 | ||
Association and stoichiometry of K(ATP) channel subunits | Q73413932 | ||
Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor | Q24304448 | ||
Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart | Q24317271 | ||
The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide | Q24532117 | ||
Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor | Q28237709 | ||
ATP-regulated K+ channels in cardiac muscle | Q28265565 | ||
Determination of the subunit stoichiometry of a voltage-activated potassium channel | Q28270398 | ||
The ABC of channel regulation | Q28297235 | ||
Cloning and expression of an inwardly rectifying ATP-regulated potassium channel | Q28297778 | ||
Adenosine 5'-triphosphate-sensitive potassium channels | Q28307662 | ||
A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels | Q28506216 | ||
ATP dependence of KATP channel kinetics in isolated membrane patches from rat ventricle | Q34088113 | ||
Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion | Q34308492 | ||
Adenosine diphosphate as an intracellular regulator of insulin secretion. | Q34382672 | ||
Regulation of KATP channel activity by diazoxide and MgADP. Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor | Q36436008 | ||
Control of Rectification and Gating of Cloned KATP Channels by the Kir6.2 Subunit | Q36445028 | ||
A single aspartate residue is involved in both intrinsic gating and blockage by Mg2+ of the inward rectifier, IRK1. | Q38306779 | ||
A Salmonella protein that is required for resistance to antimicrobial peptides and transport of potassium | Q40792988 | ||
Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels | Q41229259 | ||
Ion permeation and rectification in ATP-sensitive channels from insulin-secreting cells (RINm5F): effects of K+, Na+ and Mg2+. | Q41337059 | ||
Inward rectifier potassium channels | Q41387781 | ||
Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification | Q42282616 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | inward-rectifier potassium channel | Q841456 |
stoichiometry | Q213185 | ||
P304 | page(s) | 655-664 | |
P577 | publication date | 1997-12-01 | |
P1433 | published in | The Journal of General Physiology | Q1092259 |
P1476 | title | Octameric stoichiometry of the KATP channel complex | |
Octameric Stoichiometry of the KATP Channel Complex | |||
P478 | volume | 110 |
Q107514451 | Inward rectifying potassium channel complex, Kir6.2-SUR1 |
Q107602501 | Inward rectifying potassium channel complex, Kir6.2-SUR1 |
Q107514454 | Inward rectifying potassium channel complex, Kir6.2-SUR2A |
Q107602502 | Inward rectifying potassium channel complex, Kir6.2-SUR2A |
Q107514460 | Inward rectifying potassium channel complex, Kir6.2-SUR2B |
Q107602503 | Inward rectifying potassium channel complex, Kir6.2-SUR2B |
Q35860617 | A Conserved Residue Cluster That Governs Kinetics of ATP-dependent Gating of Kir6.2 Potassium Channels |
Q36538371 | A Kir6.2 mutation causing severe functional effects in vitro produces neonatal diabetes without the expected neurological complications |
Q90426235 | A family of orthologous proteins from centipede venoms inhibit the hKir6.2 channel |
Q34166805 | A gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome |
Q27863920 | A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes |
Q45345282 | A mutation in the ATP-binding site of the Kir6.2 subunit of the KATP channel alters coupling with the SUR2A subunit |
Q41644878 | A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels |
Q51361235 | A novel ABCC8 mutation illustrates the variability of the diabetes phenotypes associated with a single mutation |
Q27863904 | A novel KCNJ11 mutation associated with congenital hyperinsulinism reduces the intrinsic open probability of beta-cell ATP-sensitive potassium channels |
Q27865212 | A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults |
Q47754342 | A touching case of channel regulation: the ATP-sensitive K+ channel |
Q37851290 | ABC Proteins Protect the Human Body and Maintain Optimal Health |
Q36311571 | ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes |
Q34555491 | ABCC8 and ABCC9: ABC transporters that regulate K+ channels |
Q36322637 | ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target |
Q40976849 | ATP inhibition of KATP channels: control of nucleotide sensitivity by the N-terminal domain of the Kir6.2 subunit |
Q28346280 | ATP interaction with the open state of the K(ATP) channel |
Q35121325 | ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transfer |
Q33905803 | ATP-sensitive potassium channelopathies: focus on insulin secretion |
Q28344325 | ATP-sensitive potassium channels in capillaries isolated from guinea-pig heart |
Q33867615 | Activation of cGMP-Dependent Protein Kinase Stimulates Cardiac ATP-Sensitive Potassium Channels via a ROS/Calmodulin/CaMKII Signaling Cascade |
Q35227213 | Acute sulfonylurea therapy at disease onset can cause permanent remission of KATP-induced diabetes. |
Q36141596 | Adenosine Triphosphate-Sensitive Potassium Channel Kir Subunits Implicated in Cardioprotection by Diazoxide |
Q38854256 | Adenosine Triphosphate-Sensitive Potassium Currents in Heart Disease and Cardioprotection |
Q36748630 | Ageing, gender and cardiac sarcolemmal K(ATP) channels |
Q30821155 | Altered functional properties of KATP channel conferred by a novel splice variant of SUR1. |
Q38325233 | Alternative splicing of sur2 Exon 17 regulates nucleotide sensitivity of the ATP-sensitive potassium channel |
Q44300236 | Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides |
Q28217306 | Assembly limits the pharmacological complexity of ATP-sensitive potassium channels |
Q34167570 | Assembly of ROMK1 (Kir 1.1a) Inward Rectifier K+ Channel Subunits Involves Multiple Interaction Sites |
Q44709067 | Assembly, maturation, and turnover of K(ATP) channel subunits |
Q41505625 | Association betweenTCF7L2Genotype and Glycemic Control in Diabetic Patients Treated with Gliclazide |
Q34169049 | Basal Activation of ATP-Sensitive Potassium Channels in Murine Colonic Smooth Muscle Cell |
Q61800293 | Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels |
Q40644497 | Binding and effect of K ATP channel openers in the absence of Mg2+ |
Q49593867 | Cantu syndrome-associated SUR2 (ABCC9) mutations in distinct structural domains result in KATP channel gain-of-function by differential mechanisms. |
Q36135766 | Cardiac KATP channels in health and disease |
Q37553071 | Cardiac sarcolemmal K(ATP) channels: Latest twists in a questing tale! |
Q48329827 | Cell-type specific expression of ATP-sensitive potassium channels in the rat hippocampus. |
Q33673386 | Characterization and functional restoration of a potassium channel Kir6.2 pore mutation identified in congenital hyperinsulinism |
Q40947551 | Characterization of the mouse sulfonylurea receptor 1 promoter and its regulation |
Q33396331 | Chemical tools for K(+) channel biology |
Q37528283 | Cholesterol and Kir channels |
Q26865538 | Classification of H2O2as a Neuromodulator that Regulates Striatal Dopamine Release on a Subsecond Time Scale |
Q39947644 | Coassembly of different sulfonylurea receptor subtypes extends the phenotypic diversity of ATP-sensitive potassium (KATP) channels. |
Q33784431 | Comparative aspects of the function and mechanism of SUR1 and MDR1 proteins |
Q51797847 | Complex ABCC8 DNA variations in congenital hyperinsulinism: lessons from functional studies |
Q34185246 | Concerted gating mechanism underlying KATP channel inhibition by ATP. |
Q34448663 | Congenital hyperinsulinism and glucose hypersensitivity in homozygous and heterozygous carriers of Kir6.2 (KCNJ11) mutation V290M mutation: K(ATP) channel inactivation mechanism and clinical management |
Q36428374 | Congenital hyperinsulinism associated ABCC8 mutations that cause defective trafficking of ATP-sensitive K+ channels: identification and rescue |
Q34908832 | Congenital hyperinsulinism: clinical and molecular characterisation of compound heterozygous ABCC8 mutation responsive to Diazoxide therapy |
Q34175436 | Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits. |
Q53938455 | Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis |
Q42580433 | Control of Kir channel gating by cytoplasmic domain interface interactions |
Q42540742 | Correlating structure and function in ATP-sensitive K+ channels. |
Q52312167 | Cryo-electron microscopy structures and progress toward a dynamic understanding of KATP channels |
Q36568728 | Current and emerging investigational medical therapies for the treatment of overactive bladder |
Q35964119 | Current status of the E23K Kir6.2 polymorphism: implications for type-2 diabetes |
Q37878248 | Current understanding of KATP channels in neonatal diseases: focus on insulin secretion disorders |
Q41004563 | Cytoplasmic terminus domains of Kir6.x confer different nucleotide‐dependent gating on the ATP‐sensitive K+ channel |
Q34107402 | Decreased alpha-endosulfine, an endogenous regulator of ATP-sensitive potassium channels, in brains from adult Down syndrome patients |
Q34502736 | Defective trafficking and function of KATP channels caused by a sulfonylurea receptor 1 mutation associated with persistent hyperinsulinemic hypoglycemia of infancy |
Q39261263 | Destabilization of ATP-sensitive potassium channel activity by novel KCNJ11 mutations identified in congenital hyperinsulinism |
Q41074871 | Diazoxide Cardioprotection Is Independent of Adenosine Triphosphate-Sensitive Potassium Channel Kir6.1 Subunit in Response to Stress |
Q34583179 | Diazoxide maintenance of myocyte volume and contractility during stress: evidence for a non-sarcolemmal K(ATP) channel location |
Q39804124 | Diazoxide reduces status epilepticus neuron damage in diabetes |
Q36333208 | Differential mechanisms of Cantú syndrome-associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel |
Q37532733 | Differential subunit composition of the G protein-activated inward-rectifier potassium channel during cardiac development |
Q58449729 | Direct Photoaffinity Labeling of the Kir6.2 Subunit of the ATP-sensitive K+Channel by 8-Azido-ATP |
Q35042895 | Direct interaction of Na-azide with the KATP channel. |
Q36596336 | Domain Organization of the ATP-sensitive Potassium Channel Complex Examined by Fluorescence Resonance Energy Transfer |
Q36032973 | Dominantly acting ABCC8 mutations in patients with medically unresponsive hyperinsulinaemic hypoglycaemia |
Q40019050 | Dual regulation of the ATP-sensitive potassium channel by activation of cGMP-dependent protein kinase |
Q40170511 | Dual regulation of the ATP-sensitive potassium channel by caffeine |
Q28361227 | Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel |
Q29346998 | Endosomal KATP channels as a reservoir after myocardial ischemia: a role for SUR2 subunits |
Q41980695 | Evidence for sequential ion-binding loci along the inner pore of the IRK1 inward-rectifier K+ channel |
Q28512133 | Expression of ATP-sensitive K+ channel subunits during perinatal maturation in the mouse heart |
Q50147769 | Expression, purification, and electrophysiological characterization of a recombinant, fluorescent Kir6.2 in mammalian cells. |
Q44021043 | Expression, purification, and evidence for the interaction of the two nucleotide-binding folds of the sulphonylurea receptor |
Q40948080 | Extracellular links in Kir subunits control the unitary conductance of SUR/Kir6.0 ion channels. |
Q51382355 | Familial mild hyperglycemia associated with a novel ABCC8-V84I mutation within three generations |
Q38742494 | Forced Gating Motions by a Substituted Titratable Side Chain at the Bundle Crossing of a Potassium Channel |
Q40719818 | Four novel splice variants of sulfonylurea receptor 1. |
Q58449724 | Functional Analysis of a Mutant Sulfonylurea Receptor, SUR1-R1420C, That Is Responsible for Persistent Hyperinsulinemic Hypoglycemia of Infancy |
Q27864125 | Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes. |
Q46640868 | Functional effects of KCNJ11 mutations causing neonatal diabetes: enhanced activation by MgATP. |
Q43968153 | Functional expression of Kir 6.1/SUR1-K(ATP) channels in frog retinal Müller glial cells |
Q39622037 | Functional role of the activity of ATP-sensitive potassium channels in electrical behavior of hippocampal neurons: Experimental and theoretical studies |
Q35569293 | Gating mechanism of KATP channels: function fits form |
Q38480670 | Genetics of drug response in type 2 diabetes |
Q28363877 | Glimepiride block of cloned beta-cell, cardiac and smooth muscle K(ATP) channels |
Q44129326 | Glucose promotes pancreatic islet beta-cell survival through a PI 3-kinase/Akt-signaling pathway |
Q41978504 | HMR 1098 is not an SUR isotype specific inhibitor of heterologous or sarcolemmal K ATP channels |
Q33906965 | Human K(ATP) channelopathies: diseases of metabolic homeostasis |
Q34202533 | Human oocytes express ATP-sensitive K(+) channels |
Q24312137 | Human α-endosulfine, a possible regulator of sulfonylurea-sensitive K ATP channel: Molecular cloning, expression and biological properties |
Q37849578 | Hydrogen sulfide-mediated myocardial pre- and post-conditioning |
Q26749617 | Hyperinsulinemic Hypoglycemia - The Molecular Mechanisms |
Q35632861 | Hyperinsulinism and diabetes: genetic dissection of beta cell metabolism-excitation coupling in mice |
Q35625609 | Hyperinsulinism in infancy: from basic science to clinical disease. |
Q80149655 | Hyperinsulinism in mice with heterozygous loss of K(ATP) channels |
Q30476939 | Hyperinsulinism induced by targeted suppression of beta cell KATP channels |
Q33844331 | Hyperinsulinism of infancy: towards an understanding of unregulated insulin release. European Network for Research into Hyperinsulinism in Infancy. |
Q24314488 | I SA channel complexes include four subunits each of DPP6 and Kv4.2 |
Q40791919 | Identification and pharmacological correction of a membrane trafficking defect associated with a mutation in the sulfonylurea receptor causing familial hyperinsulinism |
Q42663506 | Identification of the ABC protein SapD as the subunit that confers ATP dependence to the K+-uptake systems TrkH and TrkG from Escherichia coli K-12 |
Q24795547 | Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature |
Q52618285 | Importance of the Kir6.2 N-terminus for the interaction of glibenclamide and repaglinide with the pancreatic K(ATP) channel |
Q39893357 | Incomplete dissociation of glibenclamide from wild-type and mutant pancreatic K ATP channels limits their recovery from inhibition |
Q51305397 | Increased tolerance to stress in cardiac expressed gain-of-function of adenosine triphosphate-sensitive potassium channel subunit Kir6.1. |
Q36864024 | Inhibition of Succinate Dehydrogenase by Diazoxide Is Independent of the ATP-Sensitive Potassium Channel Subunit Sulfonylurea Type 1 Receptor |
Q28578544 | Inhibition of glucose-stimulated insulin secretion by KCNJ15, a newly identified susceptibility gene for type 2 diabetes. |
Q36989788 | Inside job: ligand-receptor pharmacology beneath the plasma membrane |
Q39356763 | Interaction between mutations in the slide helix of Kir6.2 associated with neonatal diabetes and neurological symptoms |
Q40578156 | Interaction of a novel dihydropyridine K+ channel opener, A-312110, with recombinant sulphonylurea receptors and KATP channels: comparison with the cyanoguanidine P1075. |
Q28354142 | Interaction of stilbene disulphonates with cloned K(ATP) channels |
Q48910181 | Interaction of vanadate with the cloned beta cell K(ATP) channel |
Q44052261 | Intracellular signalling mechanism responsible for modulation of sarcolemmal ATP-sensitive potassium channels by nitric oxide in ventricular cardiomyocytes. |
Q40851206 | Investigation of the molecular assembly of beta-cell K(ATP) channels |
Q48914424 | Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor |
Q33852328 | Inward rectification in KATP channels: a pH switch in the pore. |
Q24296441 | Inwardly rectifying potassium channels: their structure, function, and physiological roles |
Q34311621 | Ion Channel Associated Diseases: Overview of Molecular Mechanisms |
Q28087459 | Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death |
Q33880824 | Ions, genes and insulin release: from basic science to clinical disease. Based on the 1998 R. D. Lawrence Lecture |
Q24299971 | Ito channels are octomeric complexes with four subunits of each Kv4.2 and K+ channel-interacting protein 2 |
Q38110757 | K(+) channels: function-structural overview. |
Q37634376 | K(ATP) channelopathies in the pancreas |
Q34731579 | K(ATP) channels and insulin secretion disorders |
Q33334838 | K(ATP) channels: linker between phospholipid metabolism and excitability |
Q36422478 | KATP Channels in the Cardiovascular System |
Q36815192 | KATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit |
Q27013265 | KATP channels and cardiovascular disease: suddenly a syndrome |
Q28303315 | KATP channels as molecular sensors of cellular metabolism |
Q34039980 | KATP channels gated by intracellular nucleotides and phospholipids |
Q24299531 | Kir6.2 mutations causing neonatal diabetes prevent endocytosis of ATP-sensitive potassium channels |
Q28565185 | Kir6.2 mutations causing neonatal diabetes provide new insights into Kir6.2-SUR1 interactions |
Q37333827 | Leptin regulates KATP channel trafficking in pancreatic β-cells by a signaling mechanism involving AMP-activated protein kinase (AMPK) and cAMP-dependent protein kinase (PKA). |
Q55283497 | Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. |
Q92648141 | Localization of ATP-sensitive K+ channel subunits in rat liver |
Q32108188 | Localization of pore-forming subunit of the ATP-sensitive K(+)-channel, Kir6.2, in rat brain neurons and glial cells |
Q48383865 | Localization of the ATP-sensitive K+ channel regulatory subunits SUR2A and SUR2B in the rat brain |
Q24534237 | M-LDH serves as a sarcolemmal K(ATP) channel subunit essential for cell protection against ischemia |
Q36436074 | Mechanism of ATP-sensitive K Channel Inhibition by Sulfhydryl Modification |
Q28284068 | Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA |
Q34478704 | Membrane Phospholipid Control of Nucleotide Sensitivity of K ATP Channels |
Q50067373 | Methods for Characterizing Disease-Associated ATP-Sensitive Potassium Channel Mutations |
Q40700220 | Mg2+ sensitizes KATP channels to inhibition by DIDS: dependence on the sulphonylurea receptor subunit |
Q36515292 | MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit. |
Q38201407 | Mitochondrial channels: ion fluxes and more |
Q35542470 | Mitochondrial potassium transport: the K(+) cycle. |
Q34189484 | Modeling regulation of cardiac KATP and L-type Ca2+ currents by ATP, ADP, and Mg2+ |
Q47817361 | Modulation of Mitochondrial ATP-Dependent K + Channels by Protein Kinase C |
Q34982780 | Modulation of nucleotide sensitivity of ATP-sensitive potassium channels by phosphatidylinositol-4-phosphate 5-kinase |
Q44259032 | Modulation of the trafficking efficiency and functional properties of ATP-sensitive potassium channels through a single amino acid in the sulfonylurea receptor |
Q26777728 | Molecular action of sulphonylureas on KATP channels: a real partnership between drugs and nucleotides |
Q36436065 | Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP. |
Q35046216 | Molecular analysis of the subtype-selective inhibition of cloned KATP channels by PNU-37883A |
Q33837780 | Molecular aspects of ATP-sensitive K+ channels in the cardiovascular system and K+ channel openers |
Q24320031 | Molecular basis of Kir6.2 mutations associated with neonatal diabetes or neonatal diabetes plus neurological features |
Q36445674 | Molecular basis of inward rectification: polyamine interaction sites located by combined channel and ligand mutagenesis |
Q37605024 | Molecular biology of K(ATP) channels and implications for health and disease |
Q33888944 | Molecular determinants of KATP channel inhibition by ATP. |
Q48332432 | Molecular structure of human KATP in complex with ATP and ADP. |
Q40797523 | Molecular structure of the glibenclamide binding site of the beta-cell K(ATP) channel |
Q47617967 | Monitoring Changes in the Abundance of Endogenously Expressed ATP-Sensitive Potassium (KATP) Channels in the Plasma Membrane Using Surface Biotinylation. |
Q62513812 | Morphological localisation of sulfonylurea receptor 1 in endocrine cells of human, mouse and rat pancreas |
Q35076166 | Muscle KATPChannels: Recent Insights to Energy Sensing and Myoprotection |
Q46964181 | Mutations in the ABCC8 gene encoding the SUR1 subunit of the KATP channel cause transient neonatal diabetes, permanent neonatal diabetes or permanent diabetes diagnosed outside the neonatal period |
Q73203447 | NEM modification prevents high-affinity ATP binding to the first nucleotide binding fold of the sulphonylurea receptor, SUR1 |
Q81152665 | Neonatal diabetes mellitus |
Q33928530 | New windows on the mechanism of action of K(ATP) channel openers |
Q28564824 | Novel nucleotide-binding sites in ATP-sensitive potassium channels formed at gating interfaces |
Q35842007 | On Potential Interactions between Non-selective Cation Channel TRPM4 and Sulfonylurea Receptor SUR1 |
Q44866739 | Opening of mitochondrial KATP channel induces early and delayed cardioprotective effect: role of nitric oxide |
Q36238917 | Overexpression of SUR2A generates a cardiac phenotype resistant to ischemia |
Q37794032 | Pancreatic β-cell KATP channels: Hypoglycaemia and hyperglycaemia. |
Q34481593 | Peripheral channelopathies as targets for potassium channel openers |
Q26751138 | Pharmacogenetics in type 2 diabetes: influence on response to oral hypoglycemic agents |
Q37353476 | Pharmacogenetics of oral antidiabetic drugs. |
Q42722629 | Pharmacogenomic analysis of ATP-sensitive potassium channels coexpressing the common type 2 diabetes risk variants E23K and S1369A |
Q30388214 | Pharmacogenomics of Drug Response in Type 2 Diabetes: Toward the Definition of Tailored Therapies? |
Q37409971 | Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels |
Q36829579 | Phosphoinositide-mediated gating of inwardly rectifying K(+) channels |
Q36438954 | Phosphoinositides decrease ATP sensitivity of the cardiac ATP-sensitive K(+) channel. A molecular probe for the mechanism of ATP-sensitive inhibition |
Q28206996 | Physiological and pathophysiological roles of ATP-sensitive K+ channels |
Q58544829 | Polyamines and potassium channels: A twenty five year romance |
Q45288533 | Pore-forming subunits of K-ATP channels, Kir6.1 and Kir6.2, display prominent differences in regional and cellular distribution in the rat brain |
Q61554773 | Potassium Channels, Sulphonylurea Receptors and Control of Insulin Release |
Q34427736 | Potassium channel openers in myocardial ischaemia: therapeutic potential of nicorandil |
Q77796097 | Potassium ion channels and human disease: phenotypes to drug targets? |
Q28533906 | Pregabalin Attenuates Excitotoxicity in Diabetes |
Q47617948 | Probing Subunits Interactions in KATP Channels Using Photo-Crosslinking via Genetically Encoded p-Azido-L-phenylalanine |
Q36447213 | Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating |
Q39195639 | Protective Actions of H2S in Acute Myocardial Infarction and Heart Failure |
Q28572793 | Proximal C-terminal domain of sulphonylurea receptor 2A interacts with pore-forming Kir6 subunits in KATP channels |
Q33638129 | Quaternary structure of KATP channel SUR2A nucleotide binding domains resolved by synchrotron radiation X-ray scattering |
Q39263823 | Rebuilding a macromolecular membrane complex at the atomic scale: case of the Kir6.2 potassium channel coupled to the muscarinic acetylcholine receptor M2. |
Q40387218 | Regulation of ATP-sensitive potassium channel function by protein kinase A-mediated phosphorylation in transfected HEK293 cells |
Q36436008 | Regulation of KATP channel activity by diazoxide and MgADP. Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor |
Q35880004 | Role of Derlin-1 Protein in Proteostasis Regulation of ATP-sensitive Potassium Channels |
Q43675177 | Selective blockade of mitochondrial K(ATP) channels does not impair myocardial oxygen consumption |
Q35580331 | Signaling and cellular mechanisms in cardiac protection by ischemic and pharmacological preconditioning |
Q36436497 | Stabilization of the activity of ATP-sensitive potassium channels by ion pairs formed between adjacent Kir6.2 subunits |
Q33783529 | Stimulation of neuronal KATP channels by cGMP-dependent protein kinase: involvement of ROS and 5-hydroxydecanoate-sensitive factors in signal transduction |
Q36436285 | Structural determinants of PIP(2) regulation of inward rectifier K(ATP) channels |
Q80152648 | Study of Kir6.2/KCNJ11 gene in a sudden cardiac death pedigree |
Q36015284 | Subsecond regulation of striatal dopamine release by pre‐synaptic KATP channels |
Q36438949 | Sulfonylurea and K(+)-channel opener sensitivity of K(ATP) channels. Functional coupling of Kir6.2 and SUR1 subunits |
Q28576304 | Sulfonylurea receptors regulate the channel pore in ATP-sensitive potassium channels via an intersubunit salt bridge |
Q36325858 | Sulfonylurea receptors type 1 and 2A randomly assemble to form heteromeric KATP channels of mixed subunit composition |
Q33784425 | Sulfonylurea receptors: ABC transporters that regulate ATP-sensitive K(+) channels |
Q44715007 | Sulfonylureas correct trafficking defects of ATP-sensitive potassium channels caused by mutations in the sulfonylurea receptor |
Q40234875 | Sulfonylureas correct trafficking defects of disease-causing ATP-sensitive potassium channels by binding to the channel complex |
Q42089444 | Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic study |
Q35159821 | Sulphonylurea action revisited: the post-cloning era. |
Q39335926 | Suppression of cellular invasion by glybenclamide through inhibited secretion of platelet-derived growth factor in ovarian clear cell carcinoma ES-2 cells. |
Q34718049 | Syntaxin 1A regulates surface expression of beta-cell ATP-sensitive potassium channels. |
Q41874008 | Syntaxin-1A Interacts with Distinct Domains within Nucleotide-binding Folds of Sulfonylurea Receptor 1 to Inhibit β-Cell ATP-sensitive Potassium Channels |
Q39950588 | Syntaxin-1A inhibition of P-1075, cromakalim, and diazoxide actions on mouse cardiac ATP-sensitive potassium channel |
Q34317310 | Tandem pore domain halothane-inhibited K+ channel subunits THIK1 and THIK2 assemble and form active channels |
Q29027344 | Targeted Overactivity of β Cell KATP Channels Induces Profound Neonatal Diabetes |
Q46888987 | Tetrameric subunit structure of the native brain inwardly rectifying potassium channel Kir 2.2. |
Q33952573 | The ABC of ABCS: a phylogenetic and functional classification of ABC systems in living organisms |
Q77478404 | The Antiarrhythmic Agent Cibenzoline Inhibits KATPChannels by Binding to Kir6.2 |
Q24302959 | The G53D mutation in Kir6.2 (KCNJ11) is associated with neonatal diabetes and motor dysfunction in adulthood that is improved with sulfonylurea therapy |
Q34173659 | The I182 region of k(ir)6.2 is closely associated with ligand binding in K(ATP) channel inhibition by ATP |
Q41492299 | The KATP channel in migraine pathophysiology: a novel therapeutic target for migraine. |
Q44579189 | The Kir6.1-protein, a pore-forming subunit of ATP-sensitive potassium channels, is prominently expressed by giant cholinergic interneurons in the striatum of the rat brain |
Q42616038 | The Kir6.2-F333I mutation differentially modulates KATP channels composed of SUR1 or SUR2 subunits |
Q38577066 | The interplay between metabolic homeostasis and neurodegeneration: insights into the neurometabolic nature of amyotrophic lateral sclerosis. |
Q34172980 | The kinetic and physical basis of K(ATP) channel gating: toward a unified molecular understanding |
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