| scholarly article | Q13442814 |
| P50 | author | Michael C Puljung | Q56635804 |
| P2860 | cites work | Monoallelic ABCC8 mutations are a common cause of diazoxide-unresponsive diffuse form of congenital hyperinsulinism | Q24297468 |
| Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor | Q24304448 | ||
| ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer | Q24602726 | ||
| Structural basis for the coupling between activation and inactivation gates in K(+) channels | Q24630519 | ||
| Structural mechanism of C-type inactivation in K(+) channels | Q24630547 | ||
| Flexibility in the ABC transporter MsbA: Alternating access with a twist | Q24676413 | ||
| Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channels | Q26744692 | ||
| The Nucleotide-Binding Sites of SUR1: A Mechanistic Model | Q26774807 | ||
| A primer to single-particle cryo-electron microscopy | Q27322872 | ||
| Compromised ATP binding as a mechanism of phosphoinositide modulation of ATP-sensitive K+ channels | Q44234594 | ||
| Long-chain acyl-CoA esters and phosphatidylinositol phosphates modulate ATP inhibition of KATP channels by the same mechanism | Q44619532 | ||
| Familial leucine-sensitive hypoglycemia of infancy due to a dominant mutation of the beta-cell sulfonylurea receptor | Q45050593 | ||
| Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation | Q48163532 | ||
| Molecular structure of human KATP in complex with ATP and ADP. | Q48332432 | ||
| ATP/ADP binding sites are present in the sulfonylurea binding protein associated with brain ATP-sensitive K+ channels. | Q48455408 | ||
| Nucleotide modulation of pinacidil stimulation of the cloned K(ATP) channel Kir6.2/SUR2A. | Q48890541 | ||
| Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor | Q48914424 | ||
| Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel | Q48917262 | ||
| Conformational Changes of CFTR upon Phosphorylation and ATP Binding | Q50320055 | ||
| Differential response of K(ATP) channels containing SUR2A or SUR2B subunits to nucleotides and pinacidil | Q50721092 | ||
| Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP. | Q50741434 | ||
| Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel | Q50742023 | ||
| Structure of a Pancreatic ATP-Sensitive Potassium Channel. | Q51192322 | ||
| Defining a binding pocket for sulfonylureas in ATP-sensitive potassium channels | Q51802142 | ||
| The N-terminal transmembrane domain (TMD0) and a cytosolic linker (L0) of sulphonylurea receptor define the unique intrinsic gating of KATP channels | Q51805285 | ||
| The tolbutamide site of SUR1 and a mechanism for its functional coupling to K(ATP) channel closure | Q52536703 | ||
| ATP binding properties of the nucleotide-binding folds of SUR1. | Q53826118 | ||
| Glucose dependent K+-channels in pancreatic beta-cells are regulated by intracellular ATP. | Q54151640 | ||
| Subunit stoichiometry of the pancreatic β-cell ATP-sensitive K+ channel | Q57591506 | ||
| Studies of the ATPase activity of the ABC protein SUR1 | Q59421875 | ||
| Inhibition of ATP-regulated K(+)-channels by a photoactivatable ATP-analogue in mouse pancreatic beta-cells | Q70186830 | ||
| The molecular assembly of ATP-sensitive potassium channels. Determinants on the pore forming subunit | Q78069853 | ||
| The First Nucleotide Binding Domain of the Sulfonylurea Receptor 2A Contains Regulatory Elements and Is Folded and Functions as an Independent Module | Q84468302 | ||
| Control of Kir channel gating by cytoplasmic domain interface interactions | Q42580433 | ||
| Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM. | Q42637813 | ||
| Functional clustering of mutations in the dimer interface of the nucleotide binding folds of the sulfonylurea receptor | Q43154871 | ||
| Signaling in channel/enzyme multimers: ATPase transitions in SUR module gate ATP-sensitive K+ conductance | Q43705208 | ||
| Properties of single potassium channels modulated by glucose in rat pancreatic beta-cells | Q43781805 | ||
| Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells. | Q44041726 | ||
| Phosphatidic acid stimulates cardiac KATP channels like phosphatidylinositols, but with novel gating kinetics | Q44185215 | ||
| Crystal structure and mechanism of a calcium-gated potassium channel | Q27639064 | ||
| Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels | Q27662497 | ||
| Crystal Structure of the Mammalian GIRK2 K+ Channel and Gating Regulation by G Proteins, PIP2, and Sodium | Q27674638 | ||
| Structure of a KirBac potassium channel with an open bundle crossing indicates a mechanism of channel gating | Q27676659 | ||
| Molecular mechanism of ATP binding and ion channel activation in P2X receptors | Q27678739 | ||
| Refined structures of mouse P-glycoprotein | Q27680445 | ||
| Control of KirBac3.1 Potassium Channel Gating at the Interface between Cytoplasmic Domains | Q27680657 | ||
| Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter | Q27684709 | ||
| Two regions of sulfonylurea receptor specify the spontaneous bursting and ATP inhibition of KATP channel isoforms | Q27863650 | ||
| Sur domains that associate with and gate KATP pores define a novel gatekeeper | Q28203814 | ||
| Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor | Q28237709 | ||
| Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells | Q28259615 | ||
| ATP-regulated K+ channels in cardiac muscle | Q28265565 | ||
| Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters | Q28302474 | ||
| Tetrameric structure of SUR2B revealed by electron microscopy of oriented single particles | Q28569280 | ||
| Sulfonylurea receptors regulate the channel pore in ATP-sensitive potassium channels via an intersubunit salt bridge | Q28576304 | ||
| NMR and Fluorescence Studies of Drug Binding to the First Nucleotide Binding Domain of SUR2A | Q29144208 | ||
| Structure of a bacterial multidrug ABC transporter | Q29617308 | ||
| Quaternary structure of KATP channel SUR2A nucleotide binding domains resolved by synchrotron radiation X-ray scattering | Q33638129 | ||
| Strict coupling between CFTR's catalytic cycle and gating of its Cl- ion pore revealed by distributions of open channel burst durations. | Q33666969 | ||
| Identification of the potassium channel opener site on sulfonylurea receptors | Q33874981 | ||
| Molecular determinants of KATP channel inhibition by ATP. | Q33888944 | ||
| Nucleotides and phospholipids compete for binding to the C terminus of KATP channels | Q34014094 | ||
| Mutations in the K+ channel signature sequence | Q34115135 | ||
| The I182 region of k(ir)6.2 is closely associated with ligand binding in K(ATP) channel inhibition by ATP | Q34173659 | ||
| Molecular basis for Kir6.2 channel inhibition by adenine nucleotides | Q34180112 | ||
| Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion | Q34308492 | ||
| 3-D structural and functional characterization of the purified KATP channel complex Kir6.2-SUR1. | Q34324901 | ||
| The ATP switch model for ABC transporters | Q34353789 | ||
| Structural diversity of ABC transporters. | Q34410603 | ||
| Specificity of activation by phosphoinositides determines lipid regulation of Kir channels | Q34470673 | ||
| Membrane Phospholipid Control of Nucleotide Sensitivity of K ATP Channels | Q34478704 | ||
| Defective trafficking and function of KATP channels caused by a sulfonylurea receptor 1 mutation associated with persistent hyperinsulinemic hypoglycemia of infancy | Q34502736 | ||
| N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2 | Q34618893 | ||
| Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide | Q34986893 | ||
| N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits | Q35208854 | ||
| Single-Particle Cryo-EM at Crystallographic Resolution | Q35537724 | ||
| Gating mechanism of KATP channels: function fits form | Q35569293 | ||
| Engineered interaction between SUR1 and Kir6.2 that enhances ATP sensitivity in KATP channels | Q36130308 | ||
| Octameric Stoichiometry of the KATP Channel Complex | Q36436003 | ||
| Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP. | Q36436065 | ||
| Structural determinants of PIP(2) regulation of inward rectifier K(ATP) channels | Q36436285 | ||
| Coupling between voltage sensor activation, Ca2+ binding and channel opening in large conductance (BK) potassium channels | Q36436425 | ||
| Stabilization of the activity of ATP-sensitive potassium channels by ion pairs formed between adjacent Kir6.2 subunits | Q36436497 | ||
| Phosphoinositides decrease ATP sensitivity of the cardiac ATP-sensitive K(+) channel. A molecular probe for the mechanism of ATP-sensitive inhibition | Q36438954 | ||
| Regulation of cloned ATP-sensitive K channels by phosphorylation, MgADP, and phosphatidylinositol bisphosphate (PIP(2)): a study of channel rundown and reactivation | Q36444702 | ||
| Regulation of cloned ATP-sensitive K channels by adenine nucleotides and sulfonylureas: interactions between SUR1 and positively charged domains on Kir6.2. | Q36444788 | ||
| Open State Destabilization by Atp Occupancy Is Mechanism Speeding Burst Exit Underlying KATP Channel Inhibition by Atp | Q36445257 | ||
| Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating | Q36447213 | ||
| Ligand-dependent linkage of the ATP site to inhibition gate closure in the KATP channel | Q36493543 | ||
| MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit. | Q36515292 | ||
| Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle | Q36789864 | ||
| KATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit | Q36815192 | ||
| Paternal mutation of the sulfonylurea receptor (SUR1) gene and maternal loss of 11p15 imprinted genes lead to persistent hyperinsulinism in focal adenomatous hyperplasia | Q37385123 | ||
| Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating | Q37691747 | ||
| Current understanding of KATP channels in neonatal diseases: focus on insulin secretion disorders | Q37878248 | ||
| Adenosine Triphosphate-Sensitive Potassium Currents in Heart Disease and Cardioprotection | Q38854256 | ||
| Neonatal Diabetes and the KATP Channel: From Mutation to Therapy | Q39163344 | ||
| Destabilization of ATP-sensitive potassium channel activity by novel KCNJ11 mutations identified in congenital hyperinsulinism | Q39261263 | ||
| Testing for violations of microscopic reversibility in ATP-sensitive potassium channel gating | Q39956696 | ||
| Scavenging of 14-3-3 proteins reveals their involvement in the cell-surface transport of ATP-sensitive K+ channels | Q40220582 | ||
| Structure of the transporter associated with antigen processing trapped by herpes simplex virus | Q40284359 | ||
| Effect of two amino acids in TM17 of Sulfonylurea receptor SUR1 on the binding of ATP-sensitive K+ channel modulators | Q40488478 | ||
| Phosphorylation-dependent changes in nucleotide binding, conformation, and dynamics of the first nucleotide binding domain (NBD1) of the sulfonylurea receptor 2B (SUR2B). | Q40710861 | ||
| Molecular structure of the glibenclamide binding site of the beta-cell K(ATP) channel | Q40797523 | ||
| Functional analysis of a structural model of the ATP-binding site of the KATP channel Kir6.2 subunit. | Q40949543 | ||
| Anionic phospholipids activate ATP-sensitive potassium channels | Q41126627 | ||
| A universally conserved residue in the SUR1 subunit of the KATP channel is essential for translating nucleotide binding at SUR1 into channel opening. | Q41247700 | ||
| Molecular Structure of the Human CFTR Ion Channel. | Q41598483 | ||
| Structural Basis of Substrate Recognition by the Multidrug Resistance Protein MRP1. | Q41598918 | ||
| Atomic Structure of the Cystic Fibrosis Transmembrane Conductance Regulator | Q41599873 | ||
| A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels | Q41644878 | ||
| Activation of the KATP channel by Mg-nucleotide interaction with SUR1 | Q41828735 | ||
| Sulfonylureas, ATP-sensitive K+ channels, and cellular K+ loss during hypoxia, ischemia, and metabolic inhibition in mammalian ventricle | Q41908559 | ||
| Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic study | Q42089444 | ||
| Increased cytosolic calcium. A signal for sulfonylurea-stimulated insulin release from beta cells. | Q42509549 | ||
| PIP 2 and PIP as Determinants for ATP Inhibition of K ATP Channels | Q42538515 | ||
| Regulation of cardiac Na+,Ca2+ exchange and KATP potassium channels by PIP2. | Q42555612 | ||
| P921 | main subject | cryogenic electron microscopy | Q5190506 |
| membrane protein | Q423042 | ||
| transport protein | Q2111029 | ||
| drug receptors | Q58688845 | ||
| P577 | publication date | 2018-04-23 | |
| 2018-05-07 | |||
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | The Journal of General Physiology | Q1092259 |
| P1476 | title | Cryo-electron microscopy structures and progress toward a dynamic understanding of KATP channels |
| Q64118587 | Activation mechanism of ATP-sensitive K channels explored with real-time nucleotide binding |
| Q92768080 | Kir6.2-D323 and SUR2A-Q1336: an intersubunit interaction pairing for allosteric information transfer in the KATP channel complex |
| Q94592225 | New insights into KATP channel gene mutations and neonatal diabetes mellitus |
| Q92468771 | Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry |
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