The Role of Sigma1R in Mammalian Retina

scientific article

The Role of Sigma1R in Mammalian Retina is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/978-3-319-50174-1_18
P8608Fatcat IDrelease_qina2ujzvbby5e3ehoow64vc5y
P698PubMed publication ID28315277

P50authorPenny RoonQ130284996
P2093author name stringJing Wang
Sylvia B Smith
Alan Saul
Xuezhi Cui
P2860cites workActivation of the ζ receptor 1 suppresses NMDA responses in rat retinal ganglion cellsQ83143432
Purification and characterization of the human SR 31747A-binding protein. A nuclear membrane protein related to yeast sterol isomeraseQ24319925
Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1)Q24336165
Purification, molecular cloning, and expression of the mammalian sigma1-binding siteQ24619317
Epidemiology of diabetic retinopathy, diabetic macular edema and related vision lossQ26775552
Glia-neuron interactions in the mammalian retinaQ26827435
The unfolded protein response in retinal vascular diseases: implications and therapeutic potential beyond protein foldingQ26852080
Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survivalQ28255981
Expression pattern of sigma receptor 1 mRNA and protein in mammalian retinaQ28362911
Expression of the cystine-glutamate exchanger (xc-) in retinal ganglion cells and regulation by nitric oxide and oxidative stressQ28580237
Diabetic retinopathy: seeing beyond glucose-induced microvascular disease.Q30356505
Characterization of a transformed rat retinal ganglion cell lineQ31878268
Cloning and functional characterization of a sigma receptor from rat brain.Q32104855
Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptorQ32152197
Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site.Q34197697
The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.Q34279067
The sigma-1 receptor chaperone as an inter-organelle signaling modulatorQ34356970
Sigma Receptor 1 Modulates Endoplasmic Reticulum Stress in Retinal NeuronsQ34646807
Prevention of excitotoxicity in primary retinal ganglion cells by (+)-pentazocine, a sigma receptor-1 specific ligandQ34655101
Sigma-1 receptor chaperones and diseasesQ35149248
Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (σR1).Q35247759
Sigma receptor 1 activation attenuates release of inflammatory cytokines MIP1γ, MIP2, MIP3α, and IL12 (p40/p70) by retinal Müller glial cellsQ35672189
Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchangerQ36011646
Subcellular localization of the sigma-1 receptor in retinal neurons - an electron microscopy studyQ36292378
Novel roles for α-crystallins in retinal function and diseaseQ36319594
The Sigma-2 Receptor and Progesterone Receptor Membrane Component 1 are Different Binding Sites Derived From Independent GenesQ36540952
Nitric oxide and ocular blood flow in patients with IDDM.Q36850999
In vivo protection against retinal neurodegeneration by sigma receptor 1 ligand (+)-pentazocineQ36925899
Expression, subcellular localization, and regulation of sigma receptor in retinal muller cellsQ37047868
Activation of the molecular chaperone, sigma 1 receptor, preserves cone function in a murine model of inherited retinal degenerationQ37065083
The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamateQ37092353
Analysis of sigma receptor (sigmaR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic miceQ37172896
Retinal ganglion cells in diabetesQ37195552
Pharmacology and therapeutic potential of sigma(1) receptor ligandsQ37545379
Sigma receptor 1 modulates ER stress and Bcl2 in murine retinaQ37686465
New functions of Müller cellsQ38084625
A forensic path to RGC-5 cell line identification: lessons learnedQ38131460
Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interactionQ39959189
sigma-1 receptors protect RGC-5 cells from apoptosis by regulating intracellular calcium, Bax levels, and caspase-3 activationQ40009434
Expression and function of glutamine transporters SN1 (SNAT3) and SN2 (SNAT5) in retinal Müller cellsQ40357953
What do retinal müller (glial) cells do for their neuronal 'small siblings'?Q40713038
Nitric oxide: a review of its role in retinal function and disease.Q41211113
Sigma-1 receptors do not regulate calcium influx through voltage-dependent calcium channels in mouse brain synaptosomesQ42500161
Expression of sigma receptor 1 mRNA and protein in rat retinaQ43133095
Ocular hypotensive action of topical flunarizine in the rabbit: role of sigma 1 recognition sitesQ44220872
Effects of neurosteroids on ischemia-reperfusion injury in the rat retina: role of sigma1 recognition sitesQ45056232
Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cellsQ46044065
The Ins2Akita mouse as a model of early retinal complications in diabetesQ46508398
Sigma receptor ligands protect human retinal cells against oxidative stressQ46931284
Sigma-1 and sigma-2 sites in rat brain: comparison of regional, ontogenetic, and subcellular patternsQ48095896
Effect of SA4503, a novel sigma1 receptor agonist, against glutamate neurotoxicity in cultured rat retinal neurons.Q50524780
Effect of a sigma-1 receptor agonist, cutamesine dihydrochloride (SA4503), on photoreceptor cell death against light-induced damage.Q52656825
Sigma Receptor 1 Is Preferentially Involved in Modulation of N-Methyl- D -Aspartate Receptor-Mediated Light-Evoked Excitatory Postsynaptic Currents in Rat Retinal Ganglion CellsQ57659762
Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panningQ69933125
The presence of sigma receptor subtypes in bovine retinal membranesQ73562262
A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma1 receptorsQ83038025
P407language of work or nameEnglishQ1860
P304page(s)267-284
P577publication date2017-01-01
P1433published inAdvances in Experimental Medicine and BiologyQ4686385
P1476titleThe Role of Sigma1R in Mammalian Retina
P478volume964

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cites work (P2860)
Q50178516Pharmacological profiling of sigma 1 receptor ligands by novel receptor homomer assays.
Q41716404Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa

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