scholarly article | Q13442814 |
P356 | DOI | 10.1006/BBRC.1997.7840 |
P698 | PubMed publication ID | 9425306 |
P2093 | author name string | Seth P | |
Ganapathy V | |||
Leibach FH | |||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 535-540 | |
P577 | publication date | 1997-12-01 | |
P1433 | published in | Biochemical and Biophysical Research Communications | Q864228 |
P1476 | title | Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor | |
P478 | volume | 241 |
Q37052620 | A 96-well filtration method for radioligand binding analysis of σ receptor ligands |
Q57350976 | A Medicinal-Chemistry-Guided Approach to Selective and Druglike Sigma 1 Ligands |
Q64922722 | A New Pharmacophore Model for the Design of Sigma-1 Ligands Validated on a Large Experimental Dataset. |
Q44346947 | Allosteric Modulation of Opioid G-Protein Coupled Receptors by Sigma1 Receptors |
Q48922742 | Amino acid residues in the transmembrane domain of the type 1 sigma receptor critical for ligand binding |
Q24626957 | An unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for butyrophenones |
Q34655500 | An update on the development of drugs for neuropsychiatric disorders: focusing on the sigma 1 receptor ligand |
Q37172896 | Analysis of sigma receptor (sigmaR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice |
Q24616403 | Antagonist action of progesterone at σ-receptors in the modulation of voltage-gated sodium channels |
Q46630813 | Antinociceptive effects of haloperidol and its metabolites in the formalin test in mice |
Q34103643 | Beneficial effect of the sigma(1) receptor agonist PRE-084 against the spatial learning deficits in aged rats |
Q46730440 | Binding properties of [3H]MS-377, a novel sigma receptor ligand, to rat brain membranes |
Q35591598 | Characterization and evaluation of two novel fluorescent sigma-2 receptor ligands as proliferation probes. |
Q35977409 | Characterization of pulmonary sigma receptors by radioligand binding |
Q28203832 | Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice |
Q74107161 | Correlation between neuroleptic binding to sigma(1) and sigma(2) receptors and acute dystonic reactions |
Q33574808 | Development of molecular probes for imaging sigma-2 receptors in vitro and in vivo |
Q22254034 | Differential influence of the 4F2 heavy chain and the protein related to b(0,+) amino acid transport on substrate affinity of the heteromeric b(0,+) amino acid transporter |
Q28366055 | Differential involvement of the sigma(1) (sigma(1)) receptor in the anti-amnesic effect of neuroactive steroids, as demonstrated using an in vivo antisense strategy in the mouse |
Q73850514 | Drugs of abuse and placental transport |
Q34172682 | Early development of sigma-receptor ligands |
Q34721365 | Effect of structural modification in the amine portion of substituted aminobutyl-benzamides as ligands for binding σ1 and σ2 receptors |
Q33145790 | Effects of (+)-pentazocine and 1,3-di-o-tolylguanidine (DTG), sigma (sigma) ligands, on micturition in anaesthetized rats |
Q42600971 | Effects of the psychotomimetic benzomorphan N-allylnormetazocine (SKF 10,047) on prepulse inhibition of startle in mice |
Q42230846 | Evidence for sigma-1-like receptors in isolated rat liver mitochondrial membranes |
Q36078713 | Expression of a truncated form of the endoplasmic reticulum chaperone protein, σ1 receptor, promotes mitochondrial energy depletion and apoptosis. |
Q46613593 | Expression of the purported sigma(1) (sigma(1)) receptor in the mammalian brain and its possible relevance in deficits induced by antagonism of the NMDA receptor complex as revealed using an antisense strategy |
Q28362911 | Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina |
Q40789707 | Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor |
Q37047868 | Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells |
Q28184848 | Generation and phenotypic analysis of sigma receptor type I (σ1) knockout mice |
Q43202265 | Immunocytochemical assessment of sigma-1 receptor and human sterol isomerase in breast cancer and their relationship with a series of prognostic factors |
Q30859681 | Immunocytochemical localization of the sigma(1) receptor in the adult rat central nervous system |
Q36925899 | In vivo protection against retinal neurodegeneration by sigma receptor 1 ligand (+)-pentazocine |
Q36344534 | Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression |
Q44429454 | Intracellular Dynamics of σ-1 Receptors (σ1Binding Sites) in NG108-15 Cells |
Q44384961 | Involvement of the sigma 1 receptor in the motivational effects of ethanol in mice |
Q42056420 | Isolation and characterization of alternatively spliced variants of the mouse sigma1 receptor gene, Sigmar1. |
Q39680665 | Juxtaposition of the steroid binding domain-like I and II regions constitutes a ligand binding site in the sigma-1 receptor |
Q48208355 | K+ channel modulation in rodent neurohypophysial nerve terminals by sigma receptors and not by dopamine receptors |
Q36099544 | Ligand-dependent localization and intracellular stability of sigma-1 receptors in CHO-K1 cells |
Q42520940 | MS-377, a selective sigma receptor ligand, indirectly blocks the action of PCP in the N-methyl-D-aspartate receptor ion-channel complex in primary cultured rat neuronal cells |
Q24651078 | Membrane-delimited coupling between sigma receptors and K+ channels in rat neurohypophysial terminals requires neither G-protein nor ATP |
Q48177054 | Modulation of steroidal levels by adrenalectomy/castration and inhibition of neurosteroid synthesis enzymes affect sigma1 receptor-mediated behaviour in mice |
Q51147434 | Molecular Probes for Imaging the Sigma-2 Receptor: In Vitro and In Vivo Imaging Studies. |
Q37236111 | Mu opioids and their receptors: evolution of a concept |
Q43774253 | Multiple pathways of sigma(1) receptor ligand uptakes into primary cultured neuronal cells |
Q31869459 | N-alkyl substituted analogs of the sigma receptor ligand BD1008 and traditional sigma receptor ligands affect cocaine-induced convulsions and lethality in mice |
Q44013200 | Neurosteroids enhance spontaneous glutamate release in hippocampal neurons. Possible role of metabotropic sigma1-like receptors. |
Q37161130 | New N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs as sigma2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents. |
Q28294148 | Novel sigma (sigma) receptor agonists produce antidepressant-like effects in mice |
Q37401153 | PET Radiotracers for Imaging the Proliferative Status of Solid Tumors |
Q37545379 | Pharmacology and therapeutic potential of sigma(1) receptor ligands |
Q34549698 | Photoaffinity labeling of the sigma-1 receptor with N-[3-(4-nitrophenyl)propyl]-N-dodecylamine: evidence of receptor dimers |
Q34655101 | Prevention of excitotoxicity in primary retinal ganglion cells by (+)-pentazocine, a sigma receptor-1 specific ligand |
Q36978618 | Progesterone Receptor Membrane Component 1 (PGRMC1) Expression in Murine Retina |
Q74147621 | Repeated haloperidol treatment decreases sigma(1) receptor binding but does not affect its mRNA levels in the guinea pig or rat brain |
Q34671122 | Roles of sigma-1 receptors in Alzheimer's disease. |
Q33754837 | Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding |
Q36011646 | Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchanger |
Q90741695 | Sigma 1 receptor: A novel therapeutic target in retinal disease |
Q52757903 | Sigma Receptor (σR) Ligands with Antiproliferative and Anticancer Activity. |
Q34646807 | Sigma Receptor 1 Modulates Endoplasmic Reticulum Stress in Retinal Neurons |
Q39790990 | Sigma ligands, but not N-methyl-D-aspartate antagonists, reduce levodopa-induced dyskinesias |
Q35672189 | Sigma receptor 1 activation attenuates release of inflammatory cytokines MIP1γ, MIP2, MIP3α, and IL12 (p40/p70) by retinal Müller glial cells |
Q40947540 | Sigma receptor photolabeling and sigma receptor-mediated modulation of potassium channels in tumor cells |
Q37000551 | Sigma receptors [σRs]: biology in normal and diseased states |
Q34435917 | Sigma receptors and iboga alkaloids |
Q28208172 | Sigma receptors: from discovery to highlights of their implications in the cardiovascular system |
Q28208121 | Sigma receptors: potential medications development target for anti-cocaine agents |
Q24567770 | Sigma receptors: potential targets for a new class of antidepressant drug |
Q34804462 | Sigma(1) (sigma(1)) receptor antagonists represent a new strategy against cocaine addiction and toxicity |
Q33729292 | Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel |
Q53647635 | Sigma-1 Receptor and Pain. |
Q39170894 | Sigma-1 receptor expression in the dorsal root ganglion: Reexamination using a highly specific antibody. |
Q35747885 | Sigma-1 receptor ligands: potential in the treatment of neuropsychiatric disorders |
Q51015549 | Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice. |
Q34670217 | Sigma-1 receptors and animal studies centered on pain and analgesia |
Q35879869 | Sigma-2 ligands induce tumour cell death by multiple signalling pathways. |
Q34362333 | Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy. |
Q36621308 | Sigma-2 receptors as a biomarker of proliferation in solid tumours |
Q39458668 | Sigma1 Pharmacology in the Context of Cancer |
Q48191542 | Stimulation of Sigma-1 Receptor Ameliorates Depressive-like Behaviors in CaMKIV Null Mice |
Q42521686 | Strain differences in sigma(1) receptor-mediated behaviours are related to neurosteroid levels |
Q39084919 | Structural Insights into Sigma1 Function |
Q51094825 | Structural Perspectives on Sigma-1 Receptor Function. |
Q24290163 | Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney |
Q47756273 | Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma. |
Q37052604 | Synthesis and characterization of [³H]-SN56, a novel radioligand for the σ₁ receptor |
Q39489146 | Synthesis and in vitro Evaluation of Novel Indole-Based Sigma Receptors Ligands. |
Q38995653 | Synthesis and structure-activity relationship studies of conformationally flexible tetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands. |
Q39019352 | Targeting Nanocarriers with Anisamide: Fact or Artifact? |
Q34626137 | Targeting sigma-1 receptor signaling by endogenous ligands for cardioprotection |
Q47980447 | The Impact of a Single Nucleotide Polymorphism in SIGMAR1 on Depressive Symptoms in Major Depressive Disorder and Bipolar Disorder |
Q38896659 | The Role of Sigma1R in Mammalian Retina |
Q38302196 | The anti-amnesic effects of sigma1 (sigma1) receptor agonists confirmed by in vivo antisense strategy in the mouse |
Q35028831 | The attenuation of learning impairments induced after exposure to CO or trimethyltin in mice by sigma (sigma) receptor ligands involves both sigma1 and sigma2 sites |
Q55922778 | The interaction between neuroactive steroids and the σ1 receptor function: behavioral consequences and therapeutic opportunities |
Q35632630 | The ligand binding region of the sigma-1 receptor: studies utilizing photoaffinity probes, sphingosine and N-alkylamines |
Q35021013 | The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine. |
Q33931257 | The oligomeric states of the purified sigma-1 receptor are stabilized by ligands |
Q43978439 | The sigma receptor as a ligand-regulated auxiliary potassium channel subunit |
Q24651621 | The sigma receptor: evolution of the concept in neuropsychopharmacology |
Q42601878 | The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus. |
Q33782364 | The σ2 receptor: a novel protein for the imaging and treatment of cancer |
Q64881766 | Trends in Sigma-1 Receptor Research: A 25-Year Bibliometric Analysis. |
Q37190328 | Voltage-gated sodium channel modulation by sigma-receptors in cardiac myocytes and heterologous systems |
Q28586773 | cDNA structure, genomic organization, and promoter analysis of the mouse intestinal peptide transporter PEPT1 |
Q37546082 | sigma-1 receptors in major depression and anxiety |
Q57476575 | σ Receptor ligand binding: an open-and-shut case |
Q44429451 | σ-1 Receptors (σ1Binding Sites) Form Raft-Like Microdomains and Target Lipid Droplets on the Endoplasmic Reticulum: Roles in Endoplasmic Reticulum Lipid Compartmentalization and Export |
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