scholarly article | Q13442814 |
P2093 | author name string | Gavril W Pasternak | |
Ying-Xian Pan | |||
P2860 | cites work | Progress in genetic studies of pain and analgesia | Q24289028 |
Structure of the human κ-opioid receptor in complex with JDTic | Q24308048 | ||
ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization | Q24309094 | ||
A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism | Q24317131 | ||
Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment | Q24318653 | ||
Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction | Q24320057 | ||
Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1) | Q24336165 | ||
Dynorphin-(1-13), an extraordinarily potent opioid peptide | Q24561638 | ||
Endogenous formation of morphine in human cells | Q24564112 | ||
Stereospecific Binding of the Potent Narcotic Analgesic [ 3 H]Etorphine to Rat-Brain Homogenate | Q24564253 | ||
G-protein-coupled receptor heterodimerization modulates receptor function | Q24603239 | ||
Stereospecific and Nonspecific Interactions of the Morphine Congener Levorphanol in Subcellular Fractions of Mouse Brain | Q24617460 | ||
A map of human genome variation from population-scale sequencing | Q24617794 | ||
Purification, molecular cloning, and expression of the mammalian sigma1-binding site | Q24619317 | ||
The evolution of vertebrate opioid receptors | Q24627645 | ||
Duration of action of a broad range of selective κ-opioid receptor antagonists is positively correlated with c-Jun N-terminal kinase-1 activation | Q24634808 | ||
Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids | Q24634901 | ||
Crystal structure of the β2 adrenergic receptor-Gs protein complex | Q24635327 | ||
Buprenorphine: a unique drug with complex pharmacology | Q24642980 | ||
Characterization and visualization of rat and guinea pig brain kappa opioid receptors: evidence for kappa 1 and kappa 2 opioid receptors | Q24648558 | ||
Membrane-delimited coupling between sigma receptors and K+ channels in rat neurohypophysial terminals requires neither G-protein nor ATP | Q24651078 | ||
Crystal structure of rhodopsin: A G protein-coupled receptor | Q27625972 | ||
Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions | Q27670746 | ||
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist | Q27678133 | ||
Structure of the δ-opioid receptor bound to naltrindole | Q27679153 | ||
Heterodimerization of mu and delta opioid receptors: A role in opiate synergy | Q28143344 | ||
The conserved cysteine 7.38 residue is differentially accessible in the binding-site crevices of the mu, delta, and kappa opioid receptors | Q28143769 | ||
Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in mu-opioid receptor selectivity | Q28143859 | ||
The kappa opioid nalbuphine produces gender- and dose-dependent analgesia and antianalgesia in patients with postoperative pain | Q28146053 | ||
Synthesis of analgesically active benzimidazole derivatives with basic substitutions | Q28181757 | ||
The heritability of antinociception II: pharmacogenetic mediation of three over-the-counter analgesics in mice | Q28195116 | ||
Molecular identification and functional expression of mu 3, a novel alternatively spliced variant of the human mu opiate receptor gene | Q28202872 | ||
Evaluation of the tail formalin test in mice as a new model to assess local analgesic effects | Q28210135 | ||
Selective potentiation of opioid analgesia by nonsteroidal anti-inflammatory drugs | Q28211870 | ||
Cloning of a delta opioid receptor by functional expression | Q28213132 | ||
Molecular mechanisms of nociception | Q28216291 | ||
Regulation of mu-opioid receptors by cytokines | Q28246890 | ||
Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm | Q28250678 | ||
The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog | Q28260862 | ||
Coupling of opiate receptors to adenylate cyclase: requirement for Na+ and GTP | Q33979467 | ||
Novel analgesics and molecular rearrangements in the morphine-thebaine group. III. Alcohols of the 6,14-endo-ethenotetrahydrooripavine series and derived analogs of N-allylnormorphine and -norcodeine | Q34054548 | ||
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs | Q34059522 | ||
Animal models of nociception. | Q34104197 | ||
Opioid receptor and peptide gene polymorphisms: potential implications for addictions | Q34116565 | ||
Heritability of nociception. III. Genetic relationships among commonly used assays of nociception and hypersensitivity | Q34130256 | ||
Identification of two related pentapeptides from the brain with potent opiate agonist activity | Q34134593 | ||
Naloxonazine actions in vivo | Q34162604 | ||
14-Methoxymetopon, a very potent mu-opioid receptor-selective analgesic with an unusual pharmacological profile | Q34169931 | ||
Novel opioid antagonists for opioid-induced bowel dysfunction | Q34191604 | ||
Narcotic blockade | Q34203445 | ||
Opiate Receptor: Demonstration in Nervous Tissue | Q34216480 | ||
Stereospecific interaction between narcotic analgesics and a synaptic plasm a membrane fraction of rat cerebral cortex | Q34218925 | ||
Opioid antagonists. | Q34220522 | ||
Localization of d- and l-methadone after intraventricular injection into rat brains | Q34234446 | ||
Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects | Q34235012 | ||
Strategies to manage the adverse effects of oral morphine: an evidence-based report. | Q34237576 | ||
Analgesic efficacy of parenteral metkephamid acetate in treatment of postoperative pain | Q34246799 | ||
Opiate antagonistic properties of an octapeptide somatostatin analog | Q34247017 | ||
Irreversible opiate agonists and antagonists: the 14-hydroxydihydromorphinone azines | Q34249395 | ||
Central nervous system excitatory effects of meperidine in cancer patients | Q34249774 | ||
Opiate Analgesia: Evidence for Mediation by a Subpopulation of Opiate Receptors | Q34251510 | ||
Metkephamid, a Systemically Active Analog of Methionine Enkephalin with Potent Opioid δ-Receptor Activity | Q34252131 | ||
Naloxonazine, a potent, long-lasting inhibitor of opiate binding sites | Q34253900 | ||
Metkephamid (Tyr-D-Ala-Gly-Phe-N(Me)Met-NH2), a potent opioid peptide: Receptor binding and analgesic properties | Q34253970 | ||
Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites | Q34278996 | ||
Regulation of opioid receptor function by chronic agonist exposure: constitutive activity and desensitization. | Q34283960 | ||
Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variants | Q34284204 | ||
A new method for receptor autoradiography: [3H]Opioid receptors in rat brain | Q34293252 | ||
The effects of morphine methadone and meperidine on some reflex responses of spinal animals to nociceptive stimulation. | Q34296189 | ||
Sigma antagonists potentiate opioid analgesia in rats | Q34302841 | ||
The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics. | Q34311504 | ||
A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine | Q34321618 | ||
A proteomics approach for identification of single strand DNA-binding proteins involved in transcriptional regulation of mouse mu opioid receptor gene | Q36808455 | ||
Evolution of vertebrate opioid receptors | Q36926870 | ||
Identification of five mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon. | Q36950107 | ||
Proteases for processing proneuropeptides into peptide neurotransmitters and hormones | Q37053834 | ||
The role of multidrug resistance-associated protein in the blood-brain barrier and opioid analgesia | Q37117550 | ||
Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions | Q37140009 | ||
Opioids and the control of respiration | Q37154550 | ||
Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action. | Q37175164 | ||
Opioid receptor-coupled second messenger systems | Q37179761 | ||
Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors. | Q37225259 | ||
Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior | Q37250051 | ||
Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine | Q37290396 | ||
Opposing actions of neuronal nitric oxide synthase isoforms in formalin-induced pain in mice | Q37314471 | ||
Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta-selective peptide antagonists | Q37342344 | ||
Agonist-selective endocytosis of mu opioid receptor by neurons in vivo | Q37390918 | ||
Morphine and codeine from mammalian brain | Q37412957 | ||
A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia | Q37416417 | ||
Morphine and other opiates from beef brain and adrenal | Q37526607 | ||
Pharmacology and therapeutic potential of sigma(1) receptor ligands | Q37545379 | ||
Visualization of mu1 opiate receptors in rat brain by using a computerized autoradiographic subtraction technique | Q37551154 | ||
Interaction of ligands with the opiate receptors of brain membranes: Regulation by ions and nucleotides | Q37583166 | ||
Methylnaltrexone: a novel approach for the management of opioid-induced constipation in patients with advanced illness | Q37611847 | ||
Conformationally restricted analogs of somatostatin with high mu-opiate receptor specificity | Q37673003 | ||
Current knowledge of buprenorphine and its unique pharmacological profile | Q37759279 | ||
Transcriptional and epigenetic regulation of opioid receptor genes: present and future | Q37792084 | ||
Sex and gender differences in pain and analgesia | Q37811403 | ||
The endocrine effects of long-term oral opioid therapy: a case report and review of the literature | Q37874291 | ||
Opioids can evoke direct receptor-mediated excitatory effects on sensory neurons | Q37874601 | ||
Motility disorders of the colon and rectum | Q37955721 | ||
QTc interval prolongation by d-propoxyphene: what about other analgesics? | Q38008460 | ||
Twelve reasons for considering buprenorphine as a frontline analgesic in the management of pain | Q38027251 | ||
Opioid peptide receptor studies. 4. Antisense oligodeoxynucleotide to the delta opioid receptor delineates opioid receptor subtypes | Q38290148 | ||
Differential blockade of morphine and morphine-6 beta-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein alpha subunits in rats | Q38291100 | ||
Molecular biology of the opioid receptors: structures, functions and distributions. | Q38291878 | ||
Identification of a neurorestrictive suppressor element (NRSE) in the human mu-opioid receptor gene | Q38298930 | ||
Mu opioid receptor mutant, T394A, abolishes opioid-mediated adenylyl cyclase superactivation | Q44336873 | ||
1-Aminocyclopropane carboxylic acid (ACPC) prevents mu and delta opioid tolerance | Q44336892 | ||
Murine chromosomal location of the mu and kappa opioid receptor genes | Q44337061 | ||
Selective antagonism of opioid analgesia by a sigma system | Q44337301 | ||
Antagonists at excitatory opioid receptors on sensory neurons in culture increase potency and specificity of opiate analgesics and attenuate development of tolerance/dependence | Q44337423 | ||
Selective inhibition of [D-Ala2, Glu4]deltorphin antinociception by supraspinal, but not spinal, administration of an antisense oligodeoxynucleotide to an opioid delta receptor | Q44337445 | ||
Lack of involvement of delta-1 opioid receptors in the development of physical dependence on morphine in mice. | Q44337637 | ||
Treatment with antisense oligodeoxynucleotide to the opioid delta receptor selectively inhibits delta 2-agonist antinociception | Q44337847 | ||
Expression of mu opioid receptor mRNA in rat brain: an in situ hybridization study at the single cell level | Q44337884 | ||
Proglumide selectively potentiates supraspinal mu 1 opioid analgesia in mice | Q44338204 | ||
Functional antagonism of morphine analgesia by (+)-pentazocine: evidence for an anti-opioid sigma 1 system | Q44338331 | ||
Evidence for separate involvement of different mu-opioid receptor subtypes in itch and analgesia induced by supraspinal action of opioids | Q44338413 | ||
Pre- and postsynaptic distribution of mu, delta and kappa opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord | Q44338465 | ||
Evidence for a mu-delta opioid receptor complex in CHO cells co-expressing mu and delta opioid peptide receptors | Q44338770 | ||
Beta-[3H]funaltrexamine-labeled mu-opioid receptors: species variations in molecular mass and glycosylation by complex-type, N-linked oligosaccharides. | Q44338949 | ||
Differential promoter usage of mouse mu-opioid receptor gene during development | Q44339364 | ||
Opioids excite rather than inhibit sensory neurons after chronic opioid exposure of spinal cord-ganglion cultures | Q44339515 | ||
Evidence for delta opioid receptor subtypes regulating adenylyl cyclase activity in rat brain | Q44339525 | ||
Dermorphin analogues carrying an increased positive net charge in their "message" domain display extremely high mu opioid receptor selectivity | Q44339837 | ||
7-Benzylidenenaltrexone (BNTX): a selective delta 1 opioid receptor antagonist in the mouse spinal cord | Q44339839 | ||
Dermorphin analog Tyr-D-Arg2-Phe-sarcosine-induced opioid analgesia and respiratory stimulation: the role of mu 1-receptors? | Q44340323 | ||
Identification and characterization of two new human mu opioid receptor splice variants, hMOR-1O and hMOR-1X. | Q44340471 | ||
Bioinformatic analysis of the origin, sequence and diversification of mu opioid receptors in vertebrates | Q44340476 | ||
Blockade of mu and kappa 1 opioid analgesic tolerance by NPC17742, a novel NMDA antagonist | Q44340536 | ||
[3H]-[H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2] ([3H]CTOP), a potent and highly selective peptide for mu opioid receptors in rat brain. | Q44340892 | ||
Mu opioid receptor gene polymorphisms and heroin dependence in Asian populations | Q44340982 | ||
Dextromethorphan shows efficacy in experimental pain (nociception) and opioid tolerance | Q44341045 | ||
Study of opioid receptor phosphorylation using cell-labeling method with 32P-orthrophosphate | Q44341218 | ||
Expression of mu-, delta-, and kappa-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation | Q44341541 | ||
Buprenorphine exerts its antinociceptive activity via mu 1-opioid receptors | Q44341561 | ||
Opioid antagonist activity of naltrexone-derived bivalent ligands: importance of a properly oriented molecular scaffold to guide "address" recognition at kappa opioid receptors | Q44341667 | ||
Promoter region and alternatively spliced exons of the rat mu-opioid receptor gene | Q44341695 | ||
Immunohistochemical localization of mu-opioid receptors in the central nervous system of the rat. | Q44341963 | ||
Covalent labeling of mu opioid binding site by [3H]beta-funaltrexamine. | Q44342056 | ||
A novel endocytic recycling signal that distinguishes the membrane trafficking of naturally occurring opioid receptors | Q44342658 | ||
Early duplications of opioid receptor and Peptide genes in vertebrate evolution | Q44342748 | ||
Dissociation of opioid antinociception and central gastrointestinal propulsion in the mouse: studies with naloxonazine | Q44342837 | ||
Alcohol drinking is reduced by a mu 1- but not by a delta-opioid receptor antagonist in alcohol-preferring rats | Q44342982 | ||
Complete knockout of the nociceptin/orphanin FQ receptor in the rat does not induce compensatory changes in mu, delta and kappa opioid receptors | Q44343101 | ||
Functional analysis of MOR‐1 splice variants of the mouse mu opioid receptor gene Oprm | Q44343235 | ||
An antisense oligodeoxynucleotide to the delta opioid receptor (DOR-1) inhibits morphine tolerance and acute dependence in mice | Q44343549 | ||
Peripheral kappa 1-opioid receptor-mediated analgesia in mice | Q44343737 | ||
A single residue, Lys108, of the delta-opioid receptor prevents the mu-opioid-selective ligand [D-Ala2,N-MePhe4,Gly-ol5]enkephalin from binding to the delta-opioid receptor | Q44344053 | ||
Cyclic somatostatin octapeptide analogues with high affinity and selectivity toward mu opioid receptors | Q44344391 | ||
Genetic analysis of the murine mu opioid receptor: increased complexity of Oprm gene splicing | Q44344657 | ||
The functional mu opioid receptor (OPRM1) Asn40Asp variant predicts short-term response to nicotine replacement therapy in a clinical trial | Q44344781 | ||
Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden | Q44344913 | ||
Differential sensitivity of opioid-induced feeding to naloxone and naloxonazine | Q44345097 | ||
Separation of opioid analgesia from respiratory depression: evidence for different receptor mechanisms | Q44345786 | ||
Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery | Q44345837 | ||
Opioid receptors | Q34326054 | ||
The pharmacology of mu analgesics: from patients to genes | Q34333349 | ||
GCRDb: a G-protein-coupled receptor database | Q34333530 | ||
Fingerprinting G-protein-coupled receptors | Q34340311 | ||
Highly potent novel opioid receptor agonist in the 14-alkoxymetopon series. | Q34356391 | ||
A selective delta 1 opioid receptor agonist derived from oxymorphone. Evidence for separate recognition sites for delta 1 opioid receptor agonists and antagonists | Q34356796 | ||
A potent and selective endogenous agonist for the mu-opiate receptor | Q34420509 | ||
7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors | Q34427813 | ||
Kappa opiate receptor multiplicity: evidence for two U50,488-sensitive kappa 1 subtypes and a novel kappa 3 subtype. | Q34455596 | ||
Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction | Q34463235 | ||
Opioid peptides endorphins in pituitary and brain | Q34468905 | ||
Mix and match: heterodimers and opioid tolerance | Q34522291 | ||
Buprenorphine has potent kappa opioid receptor antagonist activity | Q34551985 | ||
Binaltorphimine and nor-binaltorphimine, potent and selective kappa-opioid receptor antagonists | Q34559354 | ||
An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization | Q34580057 | ||
Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine | Q34647183 | ||
The action of morphine on the superior cervical ganglion and on the nictitating membrane of the cat. | Q34648832 | ||
Beta-arrestin-biased ligands at seven-transmembrane receptors | Q34654662 | ||
Identification and characterization of seven new exon 11-associated splice variants of the rat μ opioid receptor gene, OPRM1. | Q34671312 | ||
Regulation of beta-adrenergic receptors by guanyl-5'-yl imidodiphosphate and other purine nucleotides | Q34745463 | ||
The paralysing action of morphine on the guinea-pig ileum | Q34791123 | ||
Oligomerization of opioid receptors | Q34826270 | ||
Isolation and characterization of new exon 11-associated N-terminal splice variants of the human mu opioid receptor gene | Q34902609 | ||
Endogenous opioid peptides: multiple agonists and receptors | Q34986433 | ||
Clinical pharmacology of opioids for pain | Q35024267 | ||
Opiate receptor: autoradiographic localization in rat brain | Q35031750 | ||
Acute tolerance to narcotic analgesic drugs in rats | Q35039570 | ||
ASAP: the Alternative Splicing Annotation Project | Q35158228 | ||
Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugs | Q35172820 | ||
Agonist and antagonist properties of buprenorphine, a new antinociceptive agent | Q35176503 | ||
Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation. | Q35213193 | ||
Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance. | Q35264421 | ||
THE CLINICAL EVALUATION OF MORPHINE AND ITS SUBSTITUTES AS ANALGESICS | Q35446474 | ||
Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain | Q35593778 | ||
Expansion of the human mu-opioid receptor gene architecture: novel functional variants | Q33395205 | ||
Brain region-specific N-glycosylation and lipid rafts association of the rat mu opioid receptor | Q33589637 | ||
Regulation of opioid receptor activities | Q33601320 | ||
Molecular insights into mu opioid pharmacology: From the clinic to the bench | Q33608286 | ||
The genetic mediation of individual differences in sensitivity to pain and its inhibition | Q33679576 | ||
The mu opiate receptor as a candidate gene for pain: polymorphisms, variations in expression, nociception, and opiate responses | Q33679584 | ||
Studies on mu and delta opioid receptor selectivity utilizing chimeric and site-mutagenized receptors | Q33679621 | ||
Removal of polysialylated neural cell adhesion molecule increases morphine analgesia and interferes with tolerance in mice | Q33696971 | ||
Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain | Q33705809 | ||
Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding | Q33754837 | ||
Sensory neuron-specific receptor activation elicits central and peripheral nociceptive effects in rats | Q33783377 | ||
Gene duplication and the uniqueness of vertebrate genomes circa 1970-1999. | Q33794254 | ||
Antagonists of excitatory opioid receptor functions enhance morphine's analgesic potency and attenuate opioid tolerance/dependence liability | Q33833026 | ||
How human neuroblastoma cells make morphine | Q33854021 | ||
d-Methadone blocks morphine tolerance and N-methyl-D-aspartate-induced hyperalgesia | Q33859638 | ||
Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. | Q33873664 | ||
Sex differences in thermal nociception and morphine antinociception in rodents depend on genotype | Q33899083 | ||
14-methoxymetopon, a potent opioid, induces no respiratory depression, less sedation, and less bradycardia than sufentanil in the dog. | Q33902994 | ||
Supraspinal circuitry mediating opioid antinociception: antagonist and synergy studies in multiple sites | Q33917981 | ||
Urinary excretion of morphine and biosynthetic precursors in mice | Q33929513 | ||
Molecular mechanisms and regulation of opioid receptor signaling | Q33932163 | ||
Pain genes?: natural variation and transgenic mutants | Q33938663 | ||
Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene | Q33950375 | ||
Receptor binding and analgesic properties of oxymorphazone | Q28262450 | ||
Evidence from opiate binding studies that heroin acts through its metabolites | Q28265798 | ||
Potentiation of opiate analgesia and apparent reversal of morphine tolerance by proglumide | Q28270217 | ||
(D-Ala2)-Met-enkephalinamide: a potent, long-lasting synthetic pentapeptide analgesic | Q28277920 | ||
Naltrindole, a highly selective and potent non-peptide delta opioid receptor antagonist | Q28280800 | ||
Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications | Q28287619 | ||
Cyclazocine revisited | Q28298711 | ||
The NMDA receptor antagonist MK-801 prevents long-lasting non-associative morphine tolerance in the rat | Q28318962 | ||
Cloning and pharmacological characterization of a rat kappa opioid receptor | Q28378330 | ||
Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors | Q28378359 | ||
Molecular cloning and expression of a rat kappa opioid receptor | Q28378362 | ||
Enhanced morphine analgesia in mice lacking beta-arrestin 2 | Q28504554 | ||
Formation of mu-/kappa-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia | Q28568886 | ||
-mu opiate receptor. Charged transmembrane domain amino acids are critical for agonist recognition and intrinsic activity | Q28569235 | ||
STAT6 transcription factor binding sites with mismatches within the canonical 5'-TTC...GAA-3' motif involved in regulation of delta- and mu-opioid receptors | Q28570977 | ||
Regulation of mu-opioid receptor gene transcription by interleukin-4 and influence of an allelic variation within a STAT6 transcription factor binding site | Q28574561 | ||
Identification of three new alternatively spliced variants of the rat mu opioid receptor gene: dissociation of affinity and efficacy | Q28583036 | ||
Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia | Q28585437 | ||
Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence | Q28590279 | ||
Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system | Q28591665 | ||
G proteins and opioid receptor-mediated signalling | Q28608943 | ||
Cellular and Molecular Mechanisms of Pain | Q29011961 | ||
The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints | Q29547321 | ||
Attacking pain at its source: new perspectives on opioids | Q30047792 | ||
A Role for the Distal Carboxyl Tails in Generating the Novel Pharmacology and G Protein Activation Profile of and Opioid Receptor Hetero-oligomers | Q30053100 | ||
Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs | Q30674748 | ||
Differential gene expression--how to find new analgesic targets | Q30725850 | ||
The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization | Q30800519 | ||
Anatomical and functional correlation of the endomorphins with mu opioid receptor splice variants | Q30863898 | ||
Numerous groups of chromosomal regional paralogies strongly indicate two genome doublings at the root of the vertebrates | Q30955958 | ||
A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling | Q31532158 | ||
Cloning and characterization of a mouse sigma1 receptor. | Q32062674 | ||
Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs | Q32063802 | ||
Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor | Q32152197 | ||
Characterizing exons 11 and 1 promoters of the mu opioid receptor (Oprm) gene in transgenic mice | Q33263445 | ||
Differential binding domains of peptide and non-peptide ligands in the cloned rat kappa opioid receptor. | Q38301577 | ||
cDNA cloning of an orphan opiate receptor gene family member and its splice variant | Q38306401 | ||
Selective loss of delta opioid analgesia and binding by antisense oligodeoxynucleotides to a delta opioid receptor | Q38309388 | ||
Blockade of U50,488H analgesia by antisense oligodeoxynucleotides to a kappa-opioid receptor | Q38310421 | ||
Genomic variations and transcriptional regulation of the human mu-opioid receptor gene | Q38311454 | ||
Purification and partial amino acid sequence of a mu opioid receptor from rat brain | Q38313433 | ||
Cloning and pharmacological characterization of a rat mu opioid receptor | Q38314662 | ||
The Role of Nuclear Factor κB in Tumor Necrosis Factor-Regulated Transcription of the Human μ-Opioid Receptor Gene | Q38350256 | ||
Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor | Q38352271 | ||
Identification of an octamer-1 transcription factor binding site in the promoter of the mouse mu-opioid receptor gene | Q38352681 | ||
Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits | Q38354944 | ||
"A new deal for the drug addict": the Addiction Research Center, Lexington, Kentucky | Q38438179 | ||
Ontological development of opiate receptors in rodent brain | Q38525152 | ||
The search for a nonaddicting analgesic: has it been worth it? The twenty-third Oscar B. Hunter Memorial Award in Therapeutics lecture | Q39164380 | ||
Inhibition of specific opiate binding to synaptic membrane by cerebroside sulfatase | Q39291602 | ||
Differentiation of opiate agonist and antagonist receptor binding by protein modifying reagents | Q39313497 | ||
When it comes to opiates, just say NO. | Q39328240 | ||
Differential effects of protein-modifying reagents on receptor binding of opiate agonists and antagonists | Q39334684 | ||
Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy | Q39348026 | ||
Selective enhancement of [3H]opiate agonist binding by divalent cations | Q39363678 | ||
Oral opioid therapy for chronic peripheral and central neuropathic pain | Q39396590 | ||
Role of epidural and intrathecal narcotics and peptides in the management of cancer pain | Q39461766 | ||
Buprenorphine | Q39494290 | ||
The pharmacokinetics of heroin in patients with chronic pain | Q39554417 | ||
Metkephamid and meperidine analgesia after episiotomy | Q39558563 | ||
Increased stress and effectiveness of placebos and "active" drugs | Q39597644 | ||
Agonists at the δ‐opioid receptor modify the binding of µ‐receptor agonists to the µ–δ receptor hetero‐oligomer | Q39639691 | ||
Alternative splicing determines the post-endocytic sorting fate of G-protein-coupled receptors | Q39927610 | ||
In vivo receptor binding of the opiate partial agonist, buprenorphine, correlated with its agonistic and antagonistic actions | Q39930922 | ||
Relationships Between Stereostructure and Pharmacological Activities | Q39989756 | ||
Narcotic and narcotic antagonist analgesics | Q40010802 | ||
5 Analgesics and their Antagonists: Biochemical Aspects and Structure-Activity Relationships | Q40028052 | ||
Stereochemical factors and receptor interactions associated with narcotic analgesics | Q40038342 | ||
Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla | Q40056714 | ||
Autoradiographic localization of opiate receptors in rat brain. II. The brain stem | Q40077614 | ||
Carboxyl-terminal splicing of the rat mu opioid receptor modulates agonist-mediated internalization and receptor resensitization. | Q41037609 | ||
Implication of the first and third extracellular loops of the mu-opioid receptor in the formation of the ligand binding site: a study using chimeric mu-opioid/angiotensin receptors. | Q41046260 | ||
mu-Opioid receptor internalization: opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain | Q41054132 | ||
Immunolocalization of two mu-opioid receptor isoforms (MOR1 and MOR1B) in the rat central nervous system. | Q41065133 | ||
Transcription of the mouse mu-opioid receptor gene is regulated by two promoters | Q41078375 | ||
Dual promoters of mouse mu-opioid receptor gene | Q41109711 | ||
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene | Q41157124 | ||
Morphine activates opioid receptors without causing their rapid internalization | Q41175884 | ||
Interaction of endogenous opioid peptides and other drugs with four kappa opioid binding sites in guinea pig brain | Q41200323 | ||
Cloning and functional characterization through antisense mapping of a kappa 3-related opioid receptor | Q41341119 | ||
Distribution and targeting of a mu-opioid receptor (MOR1) in brain and spinal cord. | Q41348392 | ||
Characterization and distribution of a cloned rat mu-opioid receptor. | Q41392554 | ||
Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type | Q41460325 | ||
Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family | Q41460331 | ||
Synthesis of the skeleton of the morphine molecule by mammalian liver | Q41466253 | ||
Allosteric coupling between morphine and enkephalin receptors in vitro. | Q41553878 | ||
Further evidence for an opioid receptor complex | Q41557607 | ||
Biochemical and pharmacological evidence for opioid receptor multiplicity in the central nervous system | Q41558964 | ||
Localization to chromosome 10 of a locus influencing morphine analgesia in crosses derived from C57BL/ and DBA/2 strains | Q41680280 | ||
Spinal PKC activity and expression: role in tolerance produced by continuous spinal morphine infusion | Q41732395 | ||
Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test | Q41742888 | ||
The biosynthesis of papaverine proceeds via (S)-reticuline | Q42001654 | ||
The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea-pig ileum | Q42071850 | ||
Increased abundance of opioid receptor heteromers after chronic morphine administration | Q42081407 | ||
Dual effects of intrathecal BAM22 on nociceptive responses in acute and persistent pain--potential function of a novel receptor | Q42102016 | ||
Cardiovascular properties of metkephamid, a delta opioid receptor agonist, in man. | Q42204665 | ||
Naloxozone pretreatment modifies cardiorespiratory, temperature, and behavioral effects of morphine | Q42246481 | ||
Morphine-6-glucuronide concentrations and opioid-related side effects: a survey in cancer patients | Q42277452 | ||
Inhibition by morphine of the release of acetylcholine from the intestine of the guinea-pig | Q42366570 | ||
The effect of analgesic drugs on the release of acetylcholine from electrically stimulated guinea-pig ileum | Q42372631 | ||
Developmental expression of the mu, kappa, and delta opioid receptor mRNAs in mouse. | Q42452182 | ||
Agonist-induced mu opioid receptor phosphorylation and functional desensitization in rat thalamus | Q42502880 | ||
Medullary mu and delta opioid receptors modulate mesencephalic morphine analgesia in rats | Q42503217 | ||
Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding | Q42507483 | ||
Identification and characterization of a novel promoter of the mouse mu opioid receptor gene (Oprm) that generates eight splice variants | Q42526118 | ||
Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice. | Q42528174 | ||
Analgesic tolerance to high-efficacy agonists but not to morphine is diminished in phosphorylation-deficient S375A μ-opioid receptor knock-in mice. | Q42726520 | ||
The history of a public science: How the Addiction Research Center became the NIDA Intramural Research Program | Q43162027 | ||
Discrimination by temperature of opiate agonist and antagonist receptor binding | Q43445977 | ||
Receptor binding and biological activity of the dermorphin analog Tyr-D-Arg(2)-Phe-Sar (TAPS). | Q43562051 | ||
Autoradiographic distribution of mu1 and mu2 opioid binding in the mouse central nervous system | Q43607320 | ||
C-terminal splice variants of the mouse mu-opioid receptor differ in morphine-induced internalization and receptor resensitization | Q43612792 | ||
Molecular cloning and pharmacological characterization of the rat sigma1 receptor | Q43659980 | ||
Synergistic analgesic interactions between the periaqueductal gray and the locus coeruleus | Q43706438 | ||
Transcriptional regulation of the human mu opioid receptor (hMOR) gene: evidence of positive and negative cis-acting elements in the proximal promoter and presence of a distal promoter | Q43708231 | ||
Differential in vivo internalization of MOR-1 and MOR-1C by morphine | Q43745707 | ||
Analgesic synergy and improved motor function produced by combinations of mu-delta- and mu-kappa-opioids | Q43874302 | ||
Characterization of mu, kappa, and delta opioid binding in amphibian whole brain tissue homogenates | Q43926227 | ||
The sigma receptor as a ligand-regulated auxiliary potassium channel subunit | Q43978439 | ||
Naltrindole 5'-isothiocyanate: a nonequilibrium, highly selective delta opioid receptor antagonist | Q43993683 | ||
Kappa 3 receptors and levorphanol-induced analgesia | Q44029980 | ||
Dimerization of morphine and orphanin FQ/nociceptin receptors: generation of a novel opioid receptor subtype | Q44148511 | ||
Phylogenetic distribution of opiate receptor binding | Q44154247 | ||
Synergy between mu opioid ligands: evidence for functional interactions among mu opioid receptor subtypes | Q44186035 | ||
Genetic dissociation of opiate tolerance and physical dependence in delta-opioid receptor-1 and preproenkephalin knock-out mice. | Q44251953 | ||
The heritability of antinociception: common pharmacogenetic mediation of five neurochemically distinct analgesics | Q44285506 | ||
Relationship of spinal dynorphin neurons to delta-opioid receptors and estrogen receptor alpha: anatomical basis for ovarian sex steroid opioid antinociception. | Q44328892 | ||
Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice | Q44330314 | ||
Enhanced analgesic potency and reduced tolerance of morphine in 129/SvEv mice: evidence for a deficiency in GM1 ganglioside-regulated excitatory opioid receptor functions | Q44330324 | ||
Presence and formation of codeine and morphine in the rat | Q35612868 | ||
Genomic structure analysis of promoter sequence of a mouse mu opioid receptor gene | Q35762035 | ||
Blockade of PDGFR-β activation eliminates morphine analgesic tolerance | Q35812604 | ||
Transcriptional regulation of mouse mu opioid receptor gene in neuronal cells by poly(ADP-ribose) polymerase-1. | Q35886645 | ||
Multiple opiate receptors: déjà vu all over again | Q35908744 | ||
Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments | Q36056325 | ||
Neuronal nitric oxide synthase alternatively spliced forms: prominent functional localizations in the brain | Q36086148 | ||
How individual sensitivity to opiates can be predicted by gene analyses | Q36145129 | ||
Pharmacotherapy and pharmacogenetics of nicotine dependence | Q36213574 | ||
Direct coupling of opioid receptors to both stimulatory and inhibitory guanine nucleotide-binding proteins in F-11 neuroblastoma-sensory neuron hybrid cells | Q36213932 | ||
Search of the human proteome for endomorphin-1 and endomorphin-2 precursor proteins. | Q36282529 | ||
Molecular forms of the putative enkephalin precursor BAM-12P in bovine adrenal, pituitary, and hypothalamus | Q36287904 | ||
Opioid receptors from a lower vertebrate (Catostomus commersoni): sequence, pharmacology, coupling to a G-protein-gated inward-rectifying potassium channel (GIRK1), and evolution. | Q36304802 | ||
Functionally differentiating two neuronal nitric oxide synthase isoforms through antisense mapping: evidence for opposing NO actions on morphine analgesia and tolerance | Q36304967 | ||
Diversity and complexity of the mu opioid receptor gene: alternative pre-mRNA splicing and promoters | Q36307818 | ||
Kappa opiate receptors localized by autoradiography to deep layers of cerebral cortex: relation to sedative effects | Q36312842 | ||
Pharmacogenetics of opioid receptors and addiction | Q36339767 | ||
Blockade of tolerance to morphine but not to kappa opioids by a nitric oxide synthase inhibitor | Q36341020 | ||
Opioid peptide-derived analgesics | Q36341669 | ||
Classification of multiple morphine and enkephalin binding sites in the central nervous system | Q36374248 | ||
Differentiation of delta and mu opiate receptor localizations by light microscopic autoradiography | Q36412585 | ||
Experimental artifacts and the analysis of ligand binding data: results of a computer simulation | Q36597472 | ||
mu opiate receptor: cDNA cloning and expression | Q36641338 | ||
Molecular cloning and functional analysis of the rat mu opioid receptor gene promoter | Q36671045 | ||
Cloning and characterization of the promoter region of the mouse μ opioid receptor gene | Q36691121 | ||
Six highly active mu-selective opioid peptides identified from two synthetic combinatorial libraries | Q36694071 | ||
Structure and chromosomal mapping of genes for the mouse kappa-opioid receptor and an opioid receptor homologue (MOR-C). | Q36710182 | ||
Expression of two variants of the human mu opioid receptor mRNA in SK-N-SH cells and human brain | Q36726539 | ||
The endomorphin system and its evolving neurophysiological role | Q36747911 | ||
cDNA cloning and regional distribution of a novel member of the opioid receptor family. | Q36747990 | ||
Molecular cloning and in situ hybridization histochemistry for rat mu-opioid receptor. | Q36750924 | ||
Molecular cloning and functional expression of a mu-opioid receptor from rat brain. | Q36771913 | ||
Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors | Q36773326 | ||
The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor | Q40079119 | ||
Mechanisms of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors | Q40094154 | ||
Autoradiographic localization of opiate receptors in rat brain. III. The telencephalon | Q40097547 | ||
Effects of exogenous and endogenous opiates on the hypothalamic--pituitary--gonadal axis in the male | Q40120253 | ||
Effects of perinatal 6-hydroxydopamine treatment on opiate receptor distribution in adult brain | Q40128551 | ||
Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters | Q40142289 | ||
Clinical review of parenteral meptazinol | Q40146781 | ||
Opiate binding to membrane preparations of neuroblastoma X glioma hybrid cells NG108-15: Effects of ions and nucleotides | Q40161278 | ||
Phospholipid changes in synaptic membranes by lipolytic enzymes and subsequent restoration of opiate binding with phosphatidylserine | Q40169934 | ||
Guanine nucleotides differentiate agonist and antagonist interactions with opiate receptors | Q40172836 | ||
Evidence for the involvement of cerebroside sulfate in opiate receptor binding: Studies with Azure A and jimpy mutant mice | Q40184780 | ||
Multiple opiate receptors. Enkephalins and morphine bind to receptors of different specificity | Q40217403 | ||
Stress responsivity, addiction, and a functional variant of the human mu-opioid receptor gene | Q40218031 | ||
Specific Nonopiate Receptors for β-Endorphin | Q40248072 | ||
Indirect evidence for presynaptic location of opiate receptors on chemosensitive primary sensory neurones | Q40269813 | ||
The opioid ligand binding of human mu-opioid receptor is modulated by novel splice variants of the receptor. | Q40297383 | ||
Receptor binding and pharmacological activity of opiates in the guinea-pig intestine | Q40334374 | ||
Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G. | Q40392922 | ||
A major species of mouse mu-opioid receptor mRNA and its promoter-dependent functional polyadenylation signal | Q40425400 | ||
Transcriptional regulation of mouse mu opioid receptor gene: Sp3 isoforms (M1, M2) function as repressors in neuronal cells to regulate the mu opioid receptor gene. | Q40460029 | ||
Heterodimerization of mu- and delta-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions. | Q40469699 | ||
Differential expression of mu-opioid receptor gene in CXBK and B6 mice by Sp1. | Q40488383 | ||
Molecular biology and pharmacology of cloned opioid receptors | Q40517576 | ||
Neuron-restrictive silencer factor (NRSF) functions as a repressor in neuronal cells to regulate the mu opioid receptor gene | Q40523640 | ||
Immunohistochemical study of the expression of exon11-containing mu opioid receptor variants in mouse brain | Q40533852 | ||
Constitutive activation of the mu opioid receptor by mutation of D3.49(164), but not D3.32(147): D3.49(164) is critical for stabilization of the inactive form of the receptor and for its expression. | Q40777582 | ||
A Nonpeptide Morphine-Like Compound: Immunocytochemical Localization in the Mouse Brain | Q40842257 | ||
Comparative immunohistochemical distributions of carboxy terminus epitopes from the mu-opioid receptor splice variants MOR-1D, MOR-1 and MOR-1C in the mouse and rat CNS. | Q40853885 | ||
Sigma receptor photolabeling and sigma receptor-mediated modulation of potassium channels in tumor cells | Q40947540 | ||
Controlling the pain of cancer | Q41029166 | ||
A chimeric analysis of the opioid receptor domains critical for the binding selectivity of mu opioid ligands | Q44345890 | ||
Antinociceptive effect of buprenorphine in mu1-opioid receptor deficient CXBK mice | Q44345988 | ||
Association of functional opioid receptor genotypes with alcohol dependence in Koreans | Q44346071 | ||
Autoradiographic analysis of mu1, mu2, and delta opioid binding in the central nervous system of C57BL/6BY and CXBK (opioid receptor-deficient) mice | Q44346460 | ||
Enhanced kappa-opioid receptor-mediated analgesia by antisense targeting the sigma1 receptor | Q44346672 | ||
Dimerization of the delta opioid receptor: implication for a role in receptor internalization | Q44347088 | ||
Opioid agonist and antagonist bivalent ligands. The relationship between spacer length and selectivity at multiple opioid receptors | Q44347161 | ||
Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden | Q44347200 | ||
A polymorphism of the mu-opioid receptor gene (OPRM1) and sensitivity to the effects of alcohol in humans | Q44347594 | ||
Opioid supraspinal analgesic synergy between the amygdala and periaqueductal gray in rats | Q44347964 | ||
Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain. | Q44348080 | ||
mu Opioid receptor knockout in mice: effects on ligand-induced analgesia and morphine lethality | Q44348420 | ||
Facilitation of μ-opioid receptor activity by preventing δ-opioid receptor-mediated codegradation. | Q44348937 | ||
Delta opioid receptor enhancement of mu opioid receptor-induced antinociception in spinal cord | Q44348974 | ||
Fentanyl and its analogs desensitize the cloned mu opioid receptor. | Q44348979 | ||
Association of polymorphisms in nicotinic acetylcholine receptor alpha 4 subunit gene (CHRNA4), mu-opioid receptor gene (OPRM1), and ethanol-metabolizing enzyme genes with alcoholism in Korean patients | Q44349048 | ||
Identification of four novel exon 5 splice variants of the mouse mu-opioid receptor gene: functional consequences of C-terminal splicing | Q44349269 | ||
The human mu opioid receptor gene: 5' regulatory and intronic sequences | Q44349281 | ||
Mu and kappa opioid receptors in periaqueductal gray and rostral ventromedial medulla | Q44349292 | ||
DAMGO recognizes four residues in the third extracellular loop to discriminate between mu- and kappa-opioid receptors | Q44349592 | ||
Opioid receptor gene expression in the rat brain during ontogeny, with special reference to the mesostriatal system: an in situ hybridization study | Q44349867 | ||
Differences in delta opioid receptor antinociception, binding, and mRNA levels between BALB/c and CXBK mice | Q44349886 | ||
No heroin or morphine 6beta-glucuronide analgesia in mu-opioid receptor knockout mice | Q44350077 | ||
Transcriptional regulation of mouse mu-opioid receptor gene | Q44350146 | ||
Characterization of the 3' untranslated region of the human mu-opioid receptor (MOR-1) mRNA. | Q44350206 | ||
The role of the mu(1) opioid receptor subtype in the regulation of prolactin and growth hormone secretion by Beta-endorphin in female rats: studies with naloxonazine | Q44350655 | ||
Opioid peptide receptor studies, 11: involvement of Tyr148, Trp318 and His319 of the rat mu-opioid receptor in binding of mu-selective ligands | Q44351724 | ||
Functional role of the spatial proximity of Asp114(2.50) in TMH 2 and Asn332(7.49) in TMH 7 of the mu opioid receptor | Q44351857 | ||
Expression of mu, kappa, and delta opioid receptor messenger RNA in the human CNS: a 33P in situ hybridization study | Q44352056 | ||
Meptazinol: a novel Mu-1 selective opioid analgesic | Q44352354 | ||
ASP147 in the third transmembrane helix of the rat mu opioid receptor forms ion-pairing with morphine and naltrexone | Q44352419 | ||
Identification and characterization of three new alternatively spliced mu-opioid receptor isoforms. | Q44352433 | ||
Opioid Receptors Undergo Axonal Flow | Q44352616 | ||
A novel opioid receptor site directed alkylating agent with irreversible narcotic antagonistic and reversible agonistic activities | Q44352732 | ||
Supraspinal and spinal delta(2) opioid receptor-mediated antinociceptive synergy is mediated by spinal alpha(2) adrenoceptors | Q44352873 | ||
Selective opioid delta agonists elicit antinociceptive supraspinal/spinal synergy in the rat. | Q44352974 | ||
Ontogeny of opioid pharmacology and receptors: High and low affinity site differences | Q44352975 | ||
Mutation of human mu opioid receptor extracellular "disulfide cysteine" residues alters ligand binding but does not prevent receptor targeting to the cell plasma membrane | Q44352984 | ||
Demonstration, characterization and localization of opioid binding sites in the midgut of the insectLeucophaea maderae (Blattaria) | Q44353257 | ||
Specific μ2 opioid isoreceptor regulation of nigrostriatal neurons: in vivo evidence with naloxonazine | Q44353461 | ||
Presence of a non-peptide morphine-like compound in human cerebrospinal fluid | Q44395553 | ||
Differential sensitivities of mouse strains to morphine and [Dmt1]DALDA analgesia | Q44438207 | ||
Clinical experience of long-term treatment with epidural and intrathecal opioids--a nationwide survey | Q44447841 | ||
Analgesic Synergy Between Topical Morphine and Butamben in Mice | Q44590528 | ||
Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice. | Q44653385 | ||
The synergistic analgesic interactions between hydrocodone and ibuprofen | Q44665999 | ||
Isolation, characterization and opiate activity of beta-endorphin from human pituitary glands | Q44803522 | ||
Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite. | Q44841016 | ||
Uptake of dihydromorphine-3H by synaptosomes | Q44961544 | ||
The development of morphine tolerance and dependence is associated with translocation of protein kinase C. | Q45080390 | ||
Isolation and expression of a novel alternatively spliced mu opioid receptor isoform, MOR-1F. | Q44330378 | ||
A very high affinity opioid binding site in rat brain: demonstration by computer modeling. | Q44330414 | ||
Intracisternal A-particle element in the 3' noncoding region of the mu-opioid receptor gene in CXBK mice: a new genetic mechanism underlying differences in opioid sensitivity | Q44330465 | ||
Differential distribution in rat brain of mu opioid receptor carboxy terminal splice variants MOR-1C-like and MOR-1-like immunoreactivity: evidence for region-specific processing | Q44330816 | ||
Antinociceptive interactions of opioid delta receptor agonists with morphine in mice: supra- and sub-additivity | Q44330959 | ||
Immunohistochemical labeling of the mu opioid receptor carboxy terminal splice variant mMOR-1B4 in the mouse central nervous system | Q44331040 | ||
Editorial: peptide and peptidomimetic ligands of opioid receptors | Q44331447 | ||
Role for the C-terminus in agonist-induced mu opioid receptor phosphorylation and desensitization | Q44331716 | ||
Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties | Q44331872 | ||
Selective opioid receptor agonist and antagonist displacement of [3H]naloxone binding in amphibian brain. | Q44331916 | ||
Immunohistochemical localization of the carboxy terminus of the novel mu opioid receptor splice variant MOR-1C within the human spinal cord | Q44332187 | ||
Chronic selective activation of excitatory opioid receptor functions in sensory neurons results in opioid 'dependence' without tolerance | Q44332228 | ||
Interaction of opioid peptides and other drugs with multiple kappa receptors in rat and human brain. Evidence for species differences | Q44332263 | ||
Allelic variation S268P of the human mu-opioid receptor affects both desensitization and G protein coupling. | Q44332395 | ||
Evidence for differential opioid mu 1- and mu 2-receptor-mediated regulation of heart rate in the conscious rat. | Q44332586 | ||
The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphine but not to kappa opioids | Q44332822 | ||
Cloning and expression of an isoform of the rat mu opioid receptor (rMOR1B) which differs in agonist induced desensitization from rMOR1. | Q44332928 | ||
delta-Opioid receptor immunoreactivity: distribution in brainstem and spinal cord, and relationship to biogenic amines and enkephalin | Q44332935 | ||
Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop | Q44332936 | ||
Double in situ hybridization study on coexistence of mu-, delta- and kappa-opioid receptor mRNAs with preprotachykinin A mRNA in the rat dorsal root ganglia | Q44333074 | ||
Identification of three mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon. | Q44333140 | ||
CNS levels of mu opioid receptor (MOR-1) mRNA during chronic treatment with morphine or naltrexone | Q44333421 | ||
Circuitry linking opioid-sensitive nociceptive modulatory systems in periaqueductal gray and spinal cord with rostral ventromedial medulla | Q44333502 | ||
Identification of the amino acid residues involved in selective agonist binding in the first extracellular loop of the δ‐ and μ‐opioid receptors | Q44333522 | ||
Quantitation of μ-opioid receptor (MOR-1) mRNA in selected regions of the rat CNS | Q44333646 | ||
Differential antagonism of opioid delta antinociception by [D-Ala2,Leu5,Cys6]enkephalin and naltrindole 5'-isothiocyanate: evidence for delta receptor subtypes | Q44333780 | ||
Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence | Q44333907 | ||
Selective blockage of delta opioid receptors prevents the development of morphine tolerance and dependence in mice | Q44333988 | ||
Antisense mapping the MOR‐1 opioid receptor: evidence for alternative splicing and a novel morphine‐6β‐glucuronide receptor | Q44334055 | ||
Immunohistochemical localization of the cloned μ opioid receptor in the rat CNS | Q44334260 | ||
Genetic influences in opioid analgesic sensitivity in mice | Q44334939 | ||
Chromosomal localization of opioid peptide and receptor genes in the mouse | Q44335046 | ||
An antisense oligodeoxynucleotide to mu-opioid receptors inhibits mu-opioid receptor agonist-induced analgesia in rats | Q44335172 | ||
Gender effects and central opioid analgesia | Q44335218 | ||
Characterization of the murine mu opioid receptor gene | Q44335341 | ||
Characterization of the cloned human mu opioid receptor. | Q44335441 | ||
Mu and delta opioid synergy between the periaqueductal gray and the rostro-ventral medulla | Q44336043 | ||
Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: an in situ hybridization study | Q44336066 | ||
Intracerebroventricular treatment with an antisense oligodeoxynucleotide to kappa-opioid receptors inhibited kappa-agonist-induced analgesia in rats | Q44336222 | ||
Antisense oligodeoxynucleotide to a delta-opioid receptor selectively blocks the spinal antinociception induced by delta-, but not mu- or kappa-opioid receptor agonists in the mouse | Q44336744 | ||
Presynaptic localization of the carboxy-terminus epitopes of the mu opioid receptor splice variants MOR-1C and MOR-1D in the superficial laminae of the rat spinal cord | Q44336857 | ||
Morphine-like drugs inhibit the stimulation of E prostaglandins of cyclic AMP formation by rat brain homogenate | Q45188803 | ||
Autoradiographic evaluation of the intracerebral distribution of 3H-etorphine in the mouse brain | Q45223987 | ||
FDA: No codeine after tonsillectomy for children | Q45753888 | ||
Toward better pain control. | Q45974355 | ||
Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: studies with selective sigma-1 ligands and sigma-1 knockout mice. | Q46046241 | ||
Autoradiographic localization of opiate κ-receptors in the guinea-pig brain | Q46411966 | ||
Comparison of effects of chronic administration of naloxone and naloxonazine upon food intake and maintainance of body weight in rats | Q47182287 | ||
Pharmacological characterization of buprenorphine, a mixed agonist-antagonist with kappa 3 analgesia | Q47803503 | ||
Stereospecific interaction of opiate narcotics in binding of 3H-dihydromorphine to membranes of rat brain | Q47929774 | ||
Role of mu 1-opiate receptors in supraspinal opiate analgesia: a microinjection study | Q48087419 | ||
Pharmacological characterization of morphine-6-sulfate and codeine-6-sulfate | Q48088054 | ||
Potentiation of morphine-induced mechanical antinociception by σ₁ receptor inhibition: role of peripheral σ₁ receptors. | Q48112821 | ||
Modulation of brainstem opiate analgesia in the rat by sigma 1 receptors: a microinjection study | Q48148180 | ||
Irreversible opiate agonists and antagonists: V. Hydrazone and acylhydrazone derivatives of naltrexone | Q48164459 | ||
Topical opioids in mice: analgesia and reversal of tolerance by a topical N-methyl-D-aspartate antagonist. | Q48178126 | ||
Inhibition of opiate tolerance by non-competitive N-methyl-D-aspartate receptor antagonists | Q48191134 | ||
Blockade of morphine analgesia by an antisense oligodeoxynucleotide against the mu receptor | Q48200149 | ||
Sex differences in supraspinal morphine analgesia are dependent on genotype. | Q48205262 | ||
Children's deaths linked with postsurgical codeine | Q48223212 | ||
More codeine fatalities after tonsillectomy in North American children | Q48249814 | ||
Analysis of lamprey and hagfish genes reveals a complex history of gene duplications during early vertebrate evolution | Q48285597 | ||
Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains | Q48313634 | ||
Ontogenetic development of [3H]naloxone binding in rat brain | Q48366271 | ||
Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section | Q48370690 | ||
Differential antagonism by naltrindole-5'-isothiocyanate on [3H]DSLET and [3H]DPDPE binding to striatal slices of mice | Q48380235 | ||
C fragment of lipotropin has a high affinity for brain opiate receptors | Q48392026 | ||
Genetic differences in morphine sensitivity, tolerance and withdrawal in rats | Q48394749 | ||
The contribution of the rostral ventromedial medulla to the antinociceptive effects of systemic morphine in restrained and unrestrained rats | Q48403354 | ||
Saturable binding of dihydromorphine and naloxone to rat brain tissue in vitro | Q48443532 | ||
Opiate receptors in mice: Genetic differences | Q48445636 | ||
A peptide-like substance from pituitary that acts like morphine. I. Isolation | Q48455187 | ||
Autoradiographic localization of the opiate receptor in rat brain | Q48455214 | ||
A peptide-like substance from pituitary that acts like morphine. 2. Purification and properties | Q48455254 | ||
An endogenous morphine-like factor in mammalian brain | Q48455261 | ||
Search for an Endogenous Ligand for the Opiate Receptor | Q48461778 | ||
Identification of novel high affinity opiate receptor binding in rat brain | Q48476166 | ||
Sites of morphine induced analgesia in the primate brain: relation to pain pathways | Q48506616 | ||
Localization of opiate receptor binding in synaptic membranes of rat brain | Q48564013 | ||
Opiate receptor binding: effects of enzymatic treatments | Q48578272 | ||
Somatostatin analogs with affinity for opiate receptors in rat brain binding assay | Q48583560 | ||
Opiate agonists and antagonists discriminated by receptor binding in brain | Q48611095 | ||
Distribution of stereospecific binding of the potent narcotic analgesic etorphine in the human brain: predominance in the limbic system | Q48621260 | ||
Regional distribution of opiate receptor binding in monkey and human brain | Q48624600 | ||
Tolerance to morphine analgesia: decreased multiplicative interaction between spinal and supraspinal sites | Q48634269 | ||
Localization in brain particulate fractions of narcotic analgesic drugs administered intracisternally to rats | Q48653267 | ||
New Methods for Characterization of Complex Receptor Systems Involving 3 or More Binding Sites: Application to Brain Opiate Receptors | Q48698448 | ||
The Membrane Binding of Morphine, Diphenylhydantoin, and Tetrahydrocannabinol | Q48711513 | ||
Antisense mapping DOR-1 in mice: further support for delta receptor subtypes | Q48730514 | ||
The d- and l-isomers of methadone bind to the non-competitive site on the N-methyl-D-aspartate (NMDA) receptor in rat forebrain and spinal cord | Q48800235 | ||
Analgesic activity and central nervous system distribution of the optical isomers of pentazocine in the rat | Q48820446 | ||
Multiple opiate receptor in human brain: an autoradiographic investigation | Q48840881 | ||
mu Opiate receptor immunoreactivity in rat central nervous system | Q48873819 | ||
Uptake of morphine in particulate fractions from rat brain | Q48876497 | ||
On the central sites for the antinociceptive action of morphine and fentanyl | Q48883196 | ||
Autoradiographic localization of kappa opiate receptors to deep layers of the cerebral cortex may explain unique sedative and analgesic effects | Q48896170 | ||
Morphine allosterically modulates the binding of [3H]leucine enkephalin to a particulate fraction of rat brain | Q48946685 | ||
Morphine Tolerance, Physical Dependence, and Synthesis of Brain 5-Hydroxytryptamine | Q49118851 | ||
Studies on the Intracellular Distribution and Tissue Binding of Dihydromorphine-7,8-H3 in the Rat | Q51235697 | ||
Analgesic synergy between topical lidocaine and topical opioids. | Q51374750 | ||
Different mu receptor subtypes mediate spinal and supraspinal analgesia in mice. | Q51748873 | ||
Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5]enkephalin in the mouse. | Q51791635 | ||
Epidural injections of bupivacaine, morphine, fentanyl, lofentanil, and DADL in chronically implanted rats: a pharmacologic and pathologic study. | Q51817917 | ||
Pharmacokinetic aspects of spinal morphine analgesia. | Q51849126 | ||
Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801 | Q52052445 | ||
MK-801 inhibits the development of morphine tolerance at spinal sites. | Q52222289 | ||
An opiate-receptor gene family reunion. | Q52271316 | ||
Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains. | Q52272626 | ||
Evidence for the Neuropeptide Cholecystokinin as an Antagonist of Opiate Analgesia | Q52282916 | ||
Pharmacologic basis for the increased sensitivity of the newborn rat to morphine. | Q52284012 | ||
Targeted disruption of the neuronal nitric oxide synthase gene. | Q52507290 | ||
Retention of heroin and morphine-6 beta-glucuronide analgesia in a new line of mice lacking exon 1 of MOR-1. | Q52534596 | ||
A new series of potent analgesics: dextro 2:2-diphenyl-3-methyl-4-morpholino-butyrylpyrrolidine and related amides. I. Chemical structure and pharmacological activity. | Q52774166 | ||
The analgesic effectiveness of nalorphine and nalorphine-morphine combinations in man. | Q52777160 | ||
Novel receptor mechanisms for heroin and morphine-6 beta-glucuronide analgesia. | Q53704453 | ||
A non-peptide morphine-like compound from brain. | Q53949881 | ||
Ontogeny of opiate mechanisms in relation to the sequential development of neurons known to be components of the guinea pig's enteric nervous system. | Q53961293 | ||
Synthetic and natural opiates interact with P-glycoprotein in multidrug-resistant cells. | Q54235431 | ||
Irreversible opiate agonists and antagonists. III. Phenylhydrazone derivatives of naloxone and oxymorphone. | Q54440894 | ||
Morphine-6-glucuronide, a potent mu agonist. | Q54659247 | ||
One or two genetic loci mediate high opiate analgesia in selectively bred mice. | Q54729949 | ||
Multiple opiate receptor sites on primary afferent fibres | Q55062437 | ||
Cellular site of opiate dependence. | Q55491038 | ||
Editorial | Q56990784 | ||
Primary structure of human β-lipotropin | Q59063086 | ||
Separation of morphine analgesia from physical dependence. | Q64925884 | ||
The specificity of binding of the narcotic agonist etorphine in synaptic membranes of rat brain in vivo | Q66684685 | ||
Different receptors mediate morphine-induced prolactin and growth hormone release | Q67269131 | ||
Dissociation of morphine's analgesic and respiratory depressant actions | Q67275124 | ||
NG-nitro-L-arginine prevents morphine tolerance | Q67575808 | ||
Lack of antinociceptive cross-tolerance between [D-Pen2, D-Pen5]enkephalin and [D-Ala2]deltorphin II in mice: evidence for delta receptor subtypes | Q68247858 | ||
The opiate receptor | Q68347936 | ||
Chemical characterization and regulation of endogenous morphine and codeine in the rat | Q68825239 | ||
Mediation of anorexia by human recombinant tumor necrosis factor through a peripheral action in the rat | Q69777332 | ||
Unidirectional analgesic cross-tolerance between morphine and levorphanol in the rat | Q69829488 | ||
Differential blockade by naloxonazine of two mu opiate actions: analgesia and inhibition of gastrointestinal transit | Q69835436 | ||
Studies in vivo with ICI 174864 and [D-Pen2, D-Pen5]enkephalin | Q70087300 | ||
Attenuation and reversal of morphine tolerance by the competitive N-methyl-D-aspartate receptor antagonist, LY274614 | Q70602366 | ||
Analgesic Effect of Morphine Glucuronides | Q70653923 | ||
Demonstration and Characterization of Opiate Inhibition of the Striatal Adenylate Cyclase | Q70800101 | ||
Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay | Q71082615 | ||
Absence of cross-tolerance to heroin in morphine-tolerant mice | Q71150038 | ||
(-)-Pentazocine analgesia in mice: interactions with a sigma receptor system | Q71489821 | ||
Sigma ligands indirectly modulate the NMDA receptor-ion channel complex on intact neuronal cells via sigma 1 site | Q71668817 | ||
Nitric oxide and opioid tolerance | Q71676259 | ||
Analgesic activity of tricyclic antidepressants | Q71700789 | ||
Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance | Q71804129 | ||
Multiplicative interaction between narcotic agonisms expressed at spinal and supraspinal sites of antinociceptive action as revealed by concurrent intrathecal and intracerebroventricular injections of morphine | Q71851330 | ||
Rat strain differences in the potentiation of morphine-induced analgesia by stress | Q72061429 | ||
Naloxazone, a long-acting opiate antagonist: effects on analgesia in intact animals and on opiate receptor binding in vitro | Q72428161 | ||
Mechanisms of hormone receptor-effector coupling: the beta-adrenergic receptor and adenylate cyclase | Q72532326 | ||
Long-acting opiate agonists and antagonists: 14-hydroxydihydromorphinone hydrazones | Q72612035 | ||
Synergistic brainstem interactions for morphine analgesia | Q72636203 | ||
A New Concept on the Mode of Interaction of Narcotic Analgesics with Receptors | Q72660536 | ||
Demonstration of stereospecific opiate binding in the nervous tissue of the marine mollusc Mytilus edulis | Q72842282 | ||
Mu-opiate receptor binding is up-regulated in mice selectively bred for high stress-induced analgesia | Q72861462 | ||
Selective localization of different types of opiate receptors in hippocampus as revealed by in vitro autoradiography | Q72881997 | ||
Opiate receptor ontogeny and morphine-induced effects: Influence of chronic footshock stress in preweanling rats | Q72901748 | ||
Naloxazone irreversibly inhibits the high affinity binding of [125I]D-ala2-D-leu5-enkephalin | Q72903604 | ||
Morphine in Cow and Human Milk: Could Dietary Morphine Constitute a Ligand for Specific Morphine (μ) Receptors? | Q72904212 | ||
Strain differences in opiate receptors in mouse brain | Q72911829 | ||
Ontogeny of opiate receptors in rat forebrain: visualization by in vitro autoradiography | Q72914391 | ||
Distribution of opiate receptors in the monkey brain: an autoradiographic study | Q72927530 | ||
Prolactin and growth hormone release by morphine in the rat: different receptor mechanisms | Q72938128 | ||
Opiate, enkephalin, and endorphin analgesia: relations to a single subpopulation of opiate receptors | Q72946024 | ||
Synergistic antinociceptive interactions of morphine and clonidine in rats with nerve-ligation injury | Q73016085 | ||
Antisense mapping: assessing functional significance of genes and splice variants | Q73190576 | ||
Spinal analgesic activity of orphanin FQ/nociceptin and its fragments | Q73195158 | ||
Increased brain P-glycoprotein in morphine tolerant rats | Q73426540 | ||
Synthetic analgesics: stereochemical considerations | Q73663111 | ||
Lack of morphine and enkephalin tolerance in 129/SvEv mice: evidence for a NMDA receptor defect | Q74138281 | ||
Morphine antinociception is enhanced in mdr1a gene-deficient mice | Q74216354 | ||
Analgesics and their antagonists: some steric and chemical considerations. I. The dissociation constants of some tertiary amines and synthetic analgesics, the conformations of methadone-type compounds | Q74258500 | ||
Analgesics and their antagonists: some steric and chemical considerations. II. The influence of the basic group on physico-chemical properties and the activity of methadone and thiambutene-type compounds | Q74258504 | ||
Analgesics and their antagonists: some steric and chemical considerations. III. The influence of the basic group on the biological response | Q74258509 | ||
Genetic variance in nociception and its relationship to the potency of morphine-induced analgesia in thermal and chemical tests | Q74435399 | ||
Spinal antinociceptive synergism between morphine and clonidine persists in mice made acutely or chronically tolerant to morphine | Q74459769 | ||
Inhibition of the peristaltic reflex of the isolated guinea-pig ileum | Q74497983 | ||
Methadone analgesia in morphine-insensitive CXBK mice | Q74828238 | ||
Acute morphine dependence in mice selectively-bred for high and low analgesia | Q77684360 | ||
CENTRAL NERVOUS SYSTEM DISTRIBUTION AND METABOLISM OF C-14-MORPHINE DURING MORPHINE-INDUCED FELINE MANIA | Q78512387 | ||
Compounds Related to Pethidine--II. Mannich Bases Derived from Various Esters of 4-Carboxy-4-phenylpiperidine and Acetophenones | Q78784255 | ||
Narcotic antagonists as analgesics | Q79335988 | ||
On the contraction of muscle, chiefly in relation to the presence of ;receptive' substances: Part IV. The effect of curari and of some other substances on the nicotine response of the sartorius and gastrocnemius muscles of the frog | Q80322201 | ||
Pain in Men Wounded in Battle | Q81262005 | ||
The role of protein synthesis inhibition in the prevention of morphine tolerance | Q95781298 | ||
P433 | issue | 4 | |
P921 | main subject | opioid | Q427523 |
P304 | page(s) | 1257-1317 | |
P577 | publication date | 2013-09-27 | |
P1433 | published in | Pharmacological Reviews | Q2085079 |
P1476 | title | Mu opioids and their receptors: evolution of a concept | |
P478 | volume | 65 |