| P2093 | author name string | Gavril W Pasternak | |
| | Ying-Xian Pan | |
| P2860 | cites work | Progress in genetic studies of pain and analgesia | Q24289028 |
| | Structure of the human κ-opioid receptor in complex with JDTic | Q24308048 |
| | ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization | Q24309094 |
| | A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism | Q24317131 |
| | Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment | Q24318653 |
| | Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction | Q24320057 |
| | Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1) | Q24336165 |
| | Dynorphin-(1-13), an extraordinarily potent opioid peptide | Q24561638 |
| | Endogenous formation of morphine in human cells | Q24564112 |
| | Stereospecific Binding of the Potent Narcotic Analgesic [ 3 H]Etorphine to Rat-Brain Homogenate | Q24564253 |
| | G-protein-coupled receptor heterodimerization modulates receptor function | Q24603239 |
| | Stereospecific and Nonspecific Interactions of the Morphine Congener Levorphanol in Subcellular Fractions of Mouse Brain | Q24617460 |
| | A map of human genome variation from population-scale sequencing | Q24617794 |
| | Purification, molecular cloning, and expression of the mammalian sigma1-binding site | Q24619317 |
| | The evolution of vertebrate opioid receptors | Q24627645 |
| | Duration of action of a broad range of selective κ-opioid receptor antagonists is positively correlated with c-Jun N-terminal kinase-1 activation | Q24634808 |
| | Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids | Q24634901 |
| | Crystal structure of the β2 adrenergic receptor-Gs protein complex | Q24635327 |
| | Buprenorphine: a unique drug with complex pharmacology | Q24642980 |
| | Characterization and visualization of rat and guinea pig brain kappa opioid receptors: evidence for kappa 1 and kappa 2 opioid receptors | Q24648558 |
| | Membrane-delimited coupling between sigma receptors and K+ channels in rat neurohypophysial terminals requires neither G-protein nor ATP | Q24651078 |
| | Crystal structure of rhodopsin: A G protein-coupled receptor | Q27625972 |
| | Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions | Q27670746 |
| | Crystal structure of the µ-opioid receptor bound to a morphinan antagonist | Q27678133 |
| | Structure of the δ-opioid receptor bound to naltrindole | Q27679153 |
| | Heterodimerization of mu and delta opioid receptors: A role in opiate synergy | Q28143344 |
| | The conserved cysteine 7.38 residue is differentially accessible in the binding-site crevices of the mu, delta, and kappa opioid receptors | Q28143769 |
| | Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in mu-opioid receptor selectivity | Q28143859 |
| | The kappa opioid nalbuphine produces gender- and dose-dependent analgesia and antianalgesia in patients with postoperative pain | Q28146053 |
| | Synthesis of analgesically active benzimidazole derivatives with basic substitutions | Q28181757 |
| | The heritability of antinociception II: pharmacogenetic mediation of three over-the-counter analgesics in mice | Q28195116 |
| | Molecular identification and functional expression of mu 3, a novel alternatively spliced variant of the human mu opiate receptor gene | Q28202872 |
| | Evaluation of the tail formalin test in mice as a new model to assess local analgesic effects | Q28210135 |
| | Selective potentiation of opioid analgesia by nonsteroidal anti-inflammatory drugs | Q28211870 |
| | Cloning of a delta opioid receptor by functional expression | Q28213132 |
| | Molecular mechanisms of nociception | Q28216291 |
| | Regulation of mu-opioid receptors by cytokines | Q28246890 |
| | Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm | Q28250678 |
| | The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog | Q28260862 |
| | Coupling of opiate receptors to adenylate cyclase: requirement for Na+ and GTP | Q33979467 |
| | Novel analgesics and molecular rearrangements in the morphine-thebaine group. III. Alcohols of the 6,14-endo-ethenotetrahydrooripavine series and derived analogs of N-allylnormorphine and -norcodeine | Q34054548 |
| | Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs | Q34059522 |
| | Animal models of nociception. | Q34104197 |
| | Opioid receptor and peptide gene polymorphisms: potential implications for addictions | Q34116565 |
| | Heritability of nociception. III. Genetic relationships among commonly used assays of nociception and hypersensitivity | Q34130256 |
| | Identification of two related pentapeptides from the brain with potent opiate agonist activity | Q34134593 |
| | Naloxonazine actions in vivo | Q34162604 |
| | 14-Methoxymetopon, a very potent mu-opioid receptor-selective analgesic with an unusual pharmacological profile | Q34169931 |
| | Novel opioid antagonists for opioid-induced bowel dysfunction | Q34191604 |
| | Narcotic blockade | Q34203445 |
| | Opiate Receptor: Demonstration in Nervous Tissue | Q34216480 |
| | Stereospecific interaction between narcotic analgesics and a synaptic plasm a membrane fraction of rat cerebral cortex | Q34218925 |
| | Opioid antagonists. | Q34220522 |
| | Localization of d- and l-methadone after intraventricular injection into rat brains | Q34234446 |
| | Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects | Q34235012 |
| | Strategies to manage the adverse effects of oral morphine: an evidence-based report. | Q34237576 |
| | Analgesic efficacy of parenteral metkephamid acetate in treatment of postoperative pain | Q34246799 |
| | Opiate antagonistic properties of an octapeptide somatostatin analog | Q34247017 |
| | Irreversible opiate agonists and antagonists: the 14-hydroxydihydromorphinone azines | Q34249395 |
| | Central nervous system excitatory effects of meperidine in cancer patients | Q34249774 |
| | Opiate Analgesia: Evidence for Mediation by a Subpopulation of Opiate Receptors | Q34251510 |
| | Metkephamid, a Systemically Active Analog of Methionine Enkephalin with Potent Opioid δ-Receptor Activity | Q34252131 |
| | Naloxonazine, a potent, long-lasting inhibitor of opiate binding sites | Q34253900 |
| | Metkephamid (Tyr-D-Ala-Gly-Phe-N(Me)Met-NH2), a potent opioid peptide: Receptor binding and analgesic properties | Q34253970 |
| | Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites | Q34278996 |
| | Regulation of opioid receptor function by chronic agonist exposure: constitutive activity and desensitization. | Q34283960 |
| | Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variants | Q34284204 |
| | A new method for receptor autoradiography: [3H]Opioid receptors in rat brain | Q34293252 |
| | The effects of morphine methadone and meperidine on some reflex responses of spinal animals to nociceptive stimulation. | Q34296189 |
| | Sigma antagonists potentiate opioid analgesia in rats | Q34302841 |
| | The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics. | Q34311504 |
| | A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine | Q34321618 |
| | A proteomics approach for identification of single strand DNA-binding proteins involved in transcriptional regulation of mouse mu opioid receptor gene | Q36808455 |
| | Evolution of vertebrate opioid receptors | Q36926870 |
| | Identification of five mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon. | Q36950107 |
| | Proteases for processing proneuropeptides into peptide neurotransmitters and hormones | Q37053834 |
| | The role of multidrug resistance-associated protein in the blood-brain barrier and opioid analgesia | Q37117550 |
| | Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions | Q37140009 |
| | Opioids and the control of respiration | Q37154550 |
| | Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action. | Q37175164 |
| | Opioid receptor-coupled second messenger systems | Q37179761 |
| | Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors. | Q37225259 |
| | Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior | Q37250051 |
| | Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine | Q37290396 |
| | Opposing actions of neuronal nitric oxide synthase isoforms in formalin-induced pain in mice | Q37314471 |
| | Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta-selective peptide antagonists | Q37342344 |
| | Agonist-selective endocytosis of mu opioid receptor by neurons in vivo | Q37390918 |
| | Morphine and codeine from mammalian brain | Q37412957 |
| | A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia | Q37416417 |
| | Morphine and other opiates from beef brain and adrenal | Q37526607 |
| | Pharmacology and therapeutic potential of sigma(1) receptor ligands | Q37545379 |
| | Visualization of mu1 opiate receptors in rat brain by using a computerized autoradiographic subtraction technique | Q37551154 |
| | Interaction of ligands with the opiate receptors of brain membranes: Regulation by ions and nucleotides | Q37583166 |
| | Methylnaltrexone: a novel approach for the management of opioid-induced constipation in patients with advanced illness | Q37611847 |
| | Conformationally restricted analogs of somatostatin with high mu-opiate receptor specificity | Q37673003 |
| | Current knowledge of buprenorphine and its unique pharmacological profile | Q37759279 |
| | Transcriptional and epigenetic regulation of opioid receptor genes: present and future | Q37792084 |
| | Sex and gender differences in pain and analgesia | Q37811403 |
| | The endocrine effects of long-term oral opioid therapy: a case report and review of the literature | Q37874291 |
| | Opioids can evoke direct receptor-mediated excitatory effects on sensory neurons | Q37874601 |
| | Motility disorders of the colon and rectum | Q37955721 |
| | QTc interval prolongation by d-propoxyphene: what about other analgesics? | Q38008460 |
| | Twelve reasons for considering buprenorphine as a frontline analgesic in the management of pain | Q38027251 |
| | Opioid peptide receptor studies. 4. Antisense oligodeoxynucleotide to the delta opioid receptor delineates opioid receptor subtypes | Q38290148 |
| | Differential blockade of morphine and morphine-6 beta-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein alpha subunits in rats | Q38291100 |
| | Molecular biology of the opioid receptors: structures, functions and distributions. | Q38291878 |
| | Identification of a neurorestrictive suppressor element (NRSE) in the human mu-opioid receptor gene | Q38298930 |
| | Mu opioid receptor mutant, T394A, abolishes opioid-mediated adenylyl cyclase superactivation | Q44336873 |
| | 1-Aminocyclopropane carboxylic acid (ACPC) prevents mu and delta opioid tolerance | Q44336892 |
| | Murine chromosomal location of the mu and kappa opioid receptor genes | Q44337061 |
| | Selective antagonism of opioid analgesia by a sigma system | Q44337301 |
| | Antagonists at excitatory opioid receptors on sensory neurons in culture increase potency and specificity of opiate analgesics and attenuate development of tolerance/dependence | Q44337423 |
| | Selective inhibition of [D-Ala2, Glu4]deltorphin antinociception by supraspinal, but not spinal, administration of an antisense oligodeoxynucleotide to an opioid delta receptor | Q44337445 |
| | Lack of involvement of delta-1 opioid receptors in the development of physical dependence on morphine in mice. | Q44337637 |
| | Treatment with antisense oligodeoxynucleotide to the opioid delta receptor selectively inhibits delta 2-agonist antinociception | Q44337847 |
| | Expression of mu opioid receptor mRNA in rat brain: an in situ hybridization study at the single cell level | Q44337884 |
| | Proglumide selectively potentiates supraspinal mu 1 opioid analgesia in mice | Q44338204 |
| | Functional antagonism of morphine analgesia by (+)-pentazocine: evidence for an anti-opioid sigma 1 system | Q44338331 |
| | Evidence for separate involvement of different mu-opioid receptor subtypes in itch and analgesia induced by supraspinal action of opioids | Q44338413 |
| | Pre- and postsynaptic distribution of mu, delta and kappa opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord | Q44338465 |
| | Evidence for a mu-delta opioid receptor complex in CHO cells co-expressing mu and delta opioid peptide receptors | Q44338770 |
| | Beta-[3H]funaltrexamine-labeled mu-opioid receptors: species variations in molecular mass and glycosylation by complex-type, N-linked oligosaccharides. | Q44338949 |
| | Differential promoter usage of mouse mu-opioid receptor gene during development | Q44339364 |
| | Opioids excite rather than inhibit sensory neurons after chronic opioid exposure of spinal cord-ganglion cultures | Q44339515 |
| | Evidence for delta opioid receptor subtypes regulating adenylyl cyclase activity in rat brain | Q44339525 |
| | Dermorphin analogues carrying an increased positive net charge in their "message" domain display extremely high mu opioid receptor selectivity | Q44339837 |
| | 7-Benzylidenenaltrexone (BNTX): a selective delta 1 opioid receptor antagonist in the mouse spinal cord | Q44339839 |
| | Dermorphin analog Tyr-D-Arg2-Phe-sarcosine-induced opioid analgesia and respiratory stimulation: the role of mu 1-receptors? | Q44340323 |
| | Identification and characterization of two new human mu opioid receptor splice variants, hMOR-1O and hMOR-1X. | Q44340471 |
| | Bioinformatic analysis of the origin, sequence and diversification of mu opioid receptors in vertebrates | Q44340476 |
| | Blockade of mu and kappa 1 opioid analgesic tolerance by NPC17742, a novel NMDA antagonist | Q44340536 |
| | [3H]-[H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2] ([3H]CTOP), a potent and highly selective peptide for mu opioid receptors in rat brain. | Q44340892 |
| | Mu opioid receptor gene polymorphisms and heroin dependence in Asian populations | Q44340982 |
| | Dextromethorphan shows efficacy in experimental pain (nociception) and opioid tolerance | Q44341045 |
| | Study of opioid receptor phosphorylation using cell-labeling method with 32P-orthrophosphate | Q44341218 |
| | Expression of mu-, delta-, and kappa-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation | Q44341541 |
| | Buprenorphine exerts its antinociceptive activity via mu 1-opioid receptors | Q44341561 |
| | Opioid antagonist activity of naltrexone-derived bivalent ligands: importance of a properly oriented molecular scaffold to guide "address" recognition at kappa opioid receptors | Q44341667 |
| | Promoter region and alternatively spliced exons of the rat mu-opioid receptor gene | Q44341695 |
| | Immunohistochemical localization of mu-opioid receptors in the central nervous system of the rat. | Q44341963 |
| | Covalent labeling of mu opioid binding site by [3H]beta-funaltrexamine. | Q44342056 |
| | A novel endocytic recycling signal that distinguishes the membrane trafficking of naturally occurring opioid receptors | Q44342658 |
| | Early duplications of opioid receptor and Peptide genes in vertebrate evolution | Q44342748 |
| | Dissociation of opioid antinociception and central gastrointestinal propulsion in the mouse: studies with naloxonazine | Q44342837 |
| | Alcohol drinking is reduced by a mu 1- but not by a delta-opioid receptor antagonist in alcohol-preferring rats | Q44342982 |
| | Complete knockout of the nociceptin/orphanin FQ receptor in the rat does not induce compensatory changes in mu, delta and kappa opioid receptors | Q44343101 |
| | Functional analysis of MOR‐1 splice variants of the mouse mu opioid receptor gene Oprm | Q44343235 |
| | An antisense oligodeoxynucleotide to the delta opioid receptor (DOR-1) inhibits morphine tolerance and acute dependence in mice | Q44343549 |
| | Peripheral kappa 1-opioid receptor-mediated analgesia in mice | Q44343737 |
| | A single residue, Lys108, of the delta-opioid receptor prevents the mu-opioid-selective ligand [D-Ala2,N-MePhe4,Gly-ol5]enkephalin from binding to the delta-opioid receptor | Q44344053 |
| | Cyclic somatostatin octapeptide analogues with high affinity and selectivity toward mu opioid receptors | Q44344391 |
| | Genetic analysis of the murine mu opioid receptor: increased complexity of Oprm gene splicing | Q44344657 |
| | The functional mu opioid receptor (OPRM1) Asn40Asp variant predicts short-term response to nicotine replacement therapy in a clinical trial | Q44344781 |
| | Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden | Q44344913 |
| | Differential sensitivity of opioid-induced feeding to naloxone and naloxonazine | Q44345097 |
| | Separation of opioid analgesia from respiratory depression: evidence for different receptor mechanisms | Q44345786 |
| | Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery | Q44345837 |
| | Opioid receptors | Q34326054 |
| | The pharmacology of mu analgesics: from patients to genes | Q34333349 |
| | GCRDb: a G-protein-coupled receptor database | Q34333530 |
| | Fingerprinting G-protein-coupled receptors | Q34340311 |
| | Highly potent novel opioid receptor agonist in the 14-alkoxymetopon series. | Q34356391 |
| | A selective delta 1 opioid receptor agonist derived from oxymorphone. Evidence for separate recognition sites for delta 1 opioid receptor agonists and antagonists | Q34356796 |
| | A potent and selective endogenous agonist for the mu-opiate receptor | Q34420509 |
| | 7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors | Q34427813 |
| | Kappa opiate receptor multiplicity: evidence for two U50,488-sensitive kappa 1 subtypes and a novel kappa 3 subtype. | Q34455596 |
| | Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction | Q34463235 |
| | Opioid peptides endorphins in pituitary and brain | Q34468905 |
| | Mix and match: heterodimers and opioid tolerance | Q34522291 |
| | Buprenorphine has potent kappa opioid receptor antagonist activity | Q34551985 |
| | Binaltorphimine and nor-binaltorphimine, potent and selective kappa-opioid receptor antagonists | Q34559354 |
| | An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization | Q34580057 |
| | Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine | Q34647183 |
| | The action of morphine on the superior cervical ganglion and on the nictitating membrane of the cat. | Q34648832 |
| | Beta-arrestin-biased ligands at seven-transmembrane receptors | Q34654662 |
| | Identification and characterization of seven new exon 11-associated splice variants of the rat μ opioid receptor gene, OPRM1. | Q34671312 |
| | Regulation of beta-adrenergic receptors by guanyl-5'-yl imidodiphosphate and other purine nucleotides | Q34745463 |
| | The paralysing action of morphine on the guinea-pig ileum | Q34791123 |
| | Oligomerization of opioid receptors | Q34826270 |
| | Isolation and characterization of new exon 11-associated N-terminal splice variants of the human mu opioid receptor gene | Q34902609 |
| | Endogenous opioid peptides: multiple agonists and receptors | Q34986433 |
| | Clinical pharmacology of opioids for pain | Q35024267 |
| | Opiate receptor: autoradiographic localization in rat brain | Q35031750 |
| | Acute tolerance to narcotic analgesic drugs in rats | Q35039570 |
| | ASAP: the Alternative Splicing Annotation Project | Q35158228 |
| | Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugs | Q35172820 |
| | Agonist and antagonist properties of buprenorphine, a new antinociceptive agent | Q35176503 |
| | Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation. | Q35213193 |
| | Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance. | Q35264421 |
| | THE CLINICAL EVALUATION OF MORPHINE AND ITS SUBSTITUTES AS ANALGESICS | Q35446474 |
| | Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain | Q35593778 |
| | Expansion of the human mu-opioid receptor gene architecture: novel functional variants | Q33395205 |
| | Brain region-specific N-glycosylation and lipid rafts association of the rat mu opioid receptor | Q33589637 |
| | Regulation of opioid receptor activities | Q33601320 |
| | Molecular insights into mu opioid pharmacology: From the clinic to the bench | Q33608286 |
| | The genetic mediation of individual differences in sensitivity to pain and its inhibition | Q33679576 |
| | The mu opiate receptor as a candidate gene for pain: polymorphisms, variations in expression, nociception, and opiate responses | Q33679584 |
| | Studies on mu and delta opioid receptor selectivity utilizing chimeric and site-mutagenized receptors | Q33679621 |
| | Removal of polysialylated neural cell adhesion molecule increases morphine analgesia and interferes with tolerance in mice | Q33696971 |
| | Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain | Q33705809 |
| | Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding | Q33754837 |
| | Sensory neuron-specific receptor activation elicits central and peripheral nociceptive effects in rats | Q33783377 |
| | Gene duplication and the uniqueness of vertebrate genomes circa 1970-1999. | Q33794254 |
| | Antagonists of excitatory opioid receptor functions enhance morphine's analgesic potency and attenuate opioid tolerance/dependence liability | Q33833026 |
| | How human neuroblastoma cells make morphine | Q33854021 |
| | d-Methadone blocks morphine tolerance and N-methyl-D-aspartate-induced hyperalgesia | Q33859638 |
| | Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. | Q33873664 |
| | Sex differences in thermal nociception and morphine antinociception in rodents depend on genotype | Q33899083 |
| | 14-methoxymetopon, a potent opioid, induces no respiratory depression, less sedation, and less bradycardia than sufentanil in the dog. | Q33902994 |
| | Supraspinal circuitry mediating opioid antinociception: antagonist and synergy studies in multiple sites | Q33917981 |
| | Urinary excretion of morphine and biosynthetic precursors in mice | Q33929513 |
| | Molecular mechanisms and regulation of opioid receptor signaling | Q33932163 |
| | Pain genes?: natural variation and transgenic mutants | Q33938663 |
| | Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene | Q33950375 |
| | Receptor binding and analgesic properties of oxymorphazone | Q28262450 |
| | Evidence from opiate binding studies that heroin acts through its metabolites | Q28265798 |
| | Potentiation of opiate analgesia and apparent reversal of morphine tolerance by proglumide | Q28270217 |
| | (D-Ala2)-Met-enkephalinamide: a potent, long-lasting synthetic pentapeptide analgesic | Q28277920 |
| | Naltrindole, a highly selective and potent non-peptide delta opioid receptor antagonist | Q28280800 |
| | Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications | Q28287619 |
| | Cyclazocine revisited | Q28298711 |
| | The NMDA receptor antagonist MK-801 prevents long-lasting non-associative morphine tolerance in the rat | Q28318962 |
| | Cloning and pharmacological characterization of a rat kappa opioid receptor | Q28378330 |
| | Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors | Q28378359 |
| | Molecular cloning and expression of a rat kappa opioid receptor | Q28378362 |
| | Enhanced morphine analgesia in mice lacking beta-arrestin 2 | Q28504554 |
| | Formation of mu-/kappa-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia | Q28568886 |
| | -mu opiate receptor. Charged transmembrane domain amino acids are critical for agonist recognition and intrinsic activity | Q28569235 |
| | STAT6 transcription factor binding sites with mismatches within the canonical 5'-TTC...GAA-3' motif involved in regulation of delta- and mu-opioid receptors | Q28570977 |
| | Regulation of mu-opioid receptor gene transcription by interleukin-4 and influence of an allelic variation within a STAT6 transcription factor binding site | Q28574561 |
| | Identification of three new alternatively spliced variants of the rat mu opioid receptor gene: dissociation of affinity and efficacy | Q28583036 |
| | Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia | Q28585437 |
| | Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence | Q28590279 |
| | Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system | Q28591665 |
| | G proteins and opioid receptor-mediated signalling | Q28608943 |
| | Cellular and Molecular Mechanisms of Pain | Q29011961 |
| | The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints | Q29547321 |
| | Attacking pain at its source: new perspectives on opioids | Q30047792 |
| | A Role for the Distal Carboxyl Tails in Generating the Novel Pharmacology and G Protein Activation Profile of and Opioid Receptor Hetero-oligomers | Q30053100 |
| | Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs | Q30674748 |
| | Differential gene expression--how to find new analgesic targets | Q30725850 |
| | The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization | Q30800519 |
| | Anatomical and functional correlation of the endomorphins with mu opioid receptor splice variants | Q30863898 |
| | Numerous groups of chromosomal regional paralogies strongly indicate two genome doublings at the root of the vertebrates | Q30955958 |
| | A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling | Q31532158 |
| | Cloning and characterization of a mouse sigma1 receptor. | Q32062674 |
| | Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs | Q32063802 |
| | Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor | Q32152197 |
| | Characterizing exons 11 and 1 promoters of the mu opioid receptor (Oprm) gene in transgenic mice | Q33263445 |
| | Differential binding domains of peptide and non-peptide ligands in the cloned rat kappa opioid receptor. | Q38301577 |
| | cDNA cloning of an orphan opiate receptor gene family member and its splice variant | Q38306401 |
| | Selective loss of delta opioid analgesia and binding by antisense oligodeoxynucleotides to a delta opioid receptor | Q38309388 |
| | Blockade of U50,488H analgesia by antisense oligodeoxynucleotides to a kappa-opioid receptor | Q38310421 |
| | Genomic variations and transcriptional regulation of the human mu-opioid receptor gene | Q38311454 |
| | Purification and partial amino acid sequence of a mu opioid receptor from rat brain | Q38313433 |
| | Cloning and pharmacological characterization of a rat mu opioid receptor | Q38314662 |
| | The Role of Nuclear Factor κB in Tumor Necrosis Factor-Regulated Transcription of the Human μ-Opioid Receptor Gene | Q38350256 |
| | Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor | Q38352271 |
| | Identification of an octamer-1 transcription factor binding site in the promoter of the mouse mu-opioid receptor gene | Q38352681 |
| | Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits | Q38354944 |
| | "A new deal for the drug addict": the Addiction Research Center, Lexington, Kentucky | Q38438179 |
| | Ontological development of opiate receptors in rodent brain | Q38525152 |
| | The search for a nonaddicting analgesic: has it been worth it? The twenty-third Oscar B. Hunter Memorial Award in Therapeutics lecture | Q39164380 |
| | Inhibition of specific opiate binding to synaptic membrane by cerebroside sulfatase | Q39291602 |
| | Differentiation of opiate agonist and antagonist receptor binding by protein modifying reagents | Q39313497 |
| | When it comes to opiates, just say NO. | Q39328240 |
| | Differential effects of protein-modifying reagents on receptor binding of opiate agonists and antagonists | Q39334684 |
| | Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy | Q39348026 |
| | Selective enhancement of [3H]opiate agonist binding by divalent cations | Q39363678 |
| | Oral opioid therapy for chronic peripheral and central neuropathic pain | Q39396590 |
| | Role of epidural and intrathecal narcotics and peptides in the management of cancer pain | Q39461766 |
| | Buprenorphine | Q39494290 |
| | The pharmacokinetics of heroin in patients with chronic pain | Q39554417 |
| | Metkephamid and meperidine analgesia after episiotomy | Q39558563 |
| | Increased stress and effectiveness of placebos and "active" drugs | Q39597644 |
| | Agonists at the δ‐opioid receptor modify the binding of µ‐receptor agonists to the µ–δ receptor hetero‐oligomer | Q39639691 |
| | Alternative splicing determines the post-endocytic sorting fate of G-protein-coupled receptors | Q39927610 |
| | In vivo receptor binding of the opiate partial agonist, buprenorphine, correlated with its agonistic and antagonistic actions | Q39930922 |
| | Relationships Between Stereostructure and Pharmacological Activities | Q39989756 |
| | Narcotic and narcotic antagonist analgesics | Q40010802 |
| | 5 Analgesics and their Antagonists: Biochemical Aspects and Structure-Activity Relationships | Q40028052 |
| | Stereochemical factors and receptor interactions associated with narcotic analgesics | Q40038342 |
| | Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla | Q40056714 |
| | Autoradiographic localization of opiate receptors in rat brain. II. The brain stem | Q40077614 |
| | Carboxyl-terminal splicing of the rat mu opioid receptor modulates agonist-mediated internalization and receptor resensitization. | Q41037609 |
| | Implication of the first and third extracellular loops of the mu-opioid receptor in the formation of the ligand binding site: a study using chimeric mu-opioid/angiotensin receptors. | Q41046260 |
| | mu-Opioid receptor internalization: opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain | Q41054132 |
| | Immunolocalization of two mu-opioid receptor isoforms (MOR1 and MOR1B) in the rat central nervous system. | Q41065133 |
| | Transcription of the mouse mu-opioid receptor gene is regulated by two promoters | Q41078375 |
| | Dual promoters of mouse mu-opioid receptor gene | Q41109711 |
| | Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene | Q41157124 |
| | Morphine activates opioid receptors without causing their rapid internalization | Q41175884 |
| | Interaction of endogenous opioid peptides and other drugs with four kappa opioid binding sites in guinea pig brain | Q41200323 |
| | Cloning and functional characterization through antisense mapping of a kappa 3-related opioid receptor | Q41341119 |
| | Distribution and targeting of a mu-opioid receptor (MOR1) in brain and spinal cord. | Q41348392 |
| | Characterization and distribution of a cloned rat mu-opioid receptor. | Q41392554 |
| | Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type | Q41460325 |
| | Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family | Q41460331 |
| | Synthesis of the skeleton of the morphine molecule by mammalian liver | Q41466253 |
| | Allosteric coupling between morphine and enkephalin receptors in vitro. | Q41553878 |
| | Further evidence for an opioid receptor complex | Q41557607 |
| | Biochemical and pharmacological evidence for opioid receptor multiplicity in the central nervous system | Q41558964 |
| | Localization to chromosome 10 of a locus influencing morphine analgesia in crosses derived from C57BL/ and DBA/2 strains | Q41680280 |
| | Spinal PKC activity and expression: role in tolerance produced by continuous spinal morphine infusion | Q41732395 |
| | Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test | Q41742888 |
| | The biosynthesis of papaverine proceeds via (S)-reticuline | Q42001654 |
| | The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea-pig ileum | Q42071850 |
| | Increased abundance of opioid receptor heteromers after chronic morphine administration | Q42081407 |
| | Dual effects of intrathecal BAM22 on nociceptive responses in acute and persistent pain--potential function of a novel receptor | Q42102016 |
| | Cardiovascular properties of metkephamid, a delta opioid receptor agonist, in man. | Q42204665 |
| | Naloxozone pretreatment modifies cardiorespiratory, temperature, and behavioral effects of morphine | Q42246481 |
| | Morphine-6-glucuronide concentrations and opioid-related side effects: a survey in cancer patients | Q42277452 |
| | Inhibition by morphine of the release of acetylcholine from the intestine of the guinea-pig | Q42366570 |
| | The effect of analgesic drugs on the release of acetylcholine from electrically stimulated guinea-pig ileum | Q42372631 |
| | Developmental expression of the mu, kappa, and delta opioid receptor mRNAs in mouse. | Q42452182 |
| | Agonist-induced mu opioid receptor phosphorylation and functional desensitization in rat thalamus | Q42502880 |
| | Medullary mu and delta opioid receptors modulate mesencephalic morphine analgesia in rats | Q42503217 |
| | Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding | Q42507483 |
| | Identification and characterization of a novel promoter of the mouse mu opioid receptor gene (Oprm) that generates eight splice variants | Q42526118 |
| | Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice. | Q42528174 |
| | Analgesic tolerance to high-efficacy agonists but not to morphine is diminished in phosphorylation-deficient S375A μ-opioid receptor knock-in mice. | Q42726520 |
| | The history of a public science: How the Addiction Research Center became the NIDA Intramural Research Program | Q43162027 |
| | Discrimination by temperature of opiate agonist and antagonist receptor binding | Q43445977 |
| | Receptor binding and biological activity of the dermorphin analog Tyr-D-Arg(2)-Phe-Sar (TAPS). | Q43562051 |
| | Autoradiographic distribution of mu1 and mu2 opioid binding in the mouse central nervous system | Q43607320 |
| | C-terminal splice variants of the mouse mu-opioid receptor differ in morphine-induced internalization and receptor resensitization | Q43612792 |
| | Molecular cloning and pharmacological characterization of the rat sigma1 receptor | Q43659980 |
| | Synergistic analgesic interactions between the periaqueductal gray and the locus coeruleus | Q43706438 |
| | Transcriptional regulation of the human mu opioid receptor (hMOR) gene: evidence of positive and negative cis-acting elements in the proximal promoter and presence of a distal promoter | Q43708231 |
| | Differential in vivo internalization of MOR-1 and MOR-1C by morphine | Q43745707 |
| | Analgesic synergy and improved motor function produced by combinations of mu-delta- and mu-kappa-opioids | Q43874302 |
| | Characterization of mu, kappa, and delta opioid binding in amphibian whole brain tissue homogenates | Q43926227 |
| | The sigma receptor as a ligand-regulated auxiliary potassium channel subunit | Q43978439 |
| | Naltrindole 5'-isothiocyanate: a nonequilibrium, highly selective delta opioid receptor antagonist | Q43993683 |
| | Kappa 3 receptors and levorphanol-induced analgesia | Q44029980 |
| | Dimerization of morphine and orphanin FQ/nociceptin receptors: generation of a novel opioid receptor subtype | Q44148511 |
| | Phylogenetic distribution of opiate receptor binding | Q44154247 |
| | Synergy between mu opioid ligands: evidence for functional interactions among mu opioid receptor subtypes | Q44186035 |
| | Genetic dissociation of opiate tolerance and physical dependence in delta-opioid receptor-1 and preproenkephalin knock-out mice. | Q44251953 |
| | The heritability of antinociception: common pharmacogenetic mediation of five neurochemically distinct analgesics | Q44285506 |
| | Relationship of spinal dynorphin neurons to delta-opioid receptors and estrogen receptor alpha: anatomical basis for ovarian sex steroid opioid antinociception. | Q44328892 |
| | Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice | Q44330314 |
| | Enhanced analgesic potency and reduced tolerance of morphine in 129/SvEv mice: evidence for a deficiency in GM1 ganglioside-regulated excitatory opioid receptor functions | Q44330324 |
| | Presence and formation of codeine and morphine in the rat | Q35612868 |
| | Genomic structure analysis of promoter sequence of a mouse mu opioid receptor gene | Q35762035 |
| | Blockade of PDGFR-β activation eliminates morphine analgesic tolerance | Q35812604 |
| | Transcriptional regulation of mouse mu opioid receptor gene in neuronal cells by poly(ADP-ribose) polymerase-1. | Q35886645 |
| | Multiple opiate receptors: déjà vu all over again | Q35908744 |
| | Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments | Q36056325 |
| | Neuronal nitric oxide synthase alternatively spliced forms: prominent functional localizations in the brain | Q36086148 |
| | How individual sensitivity to opiates can be predicted by gene analyses | Q36145129 |
| | Pharmacotherapy and pharmacogenetics of nicotine dependence | Q36213574 |
| | Direct coupling of opioid receptors to both stimulatory and inhibitory guanine nucleotide-binding proteins in F-11 neuroblastoma-sensory neuron hybrid cells | Q36213932 |
| | Search of the human proteome for endomorphin-1 and endomorphin-2 precursor proteins. | Q36282529 |
| | Molecular forms of the putative enkephalin precursor BAM-12P in bovine adrenal, pituitary, and hypothalamus | Q36287904 |
| | Opioid receptors from a lower vertebrate (Catostomus commersoni): sequence, pharmacology, coupling to a G-protein-gated inward-rectifying potassium channel (GIRK1), and evolution. | Q36304802 |
| | Functionally differentiating two neuronal nitric oxide synthase isoforms through antisense mapping: evidence for opposing NO actions on morphine analgesia and tolerance | Q36304967 |
| | Diversity and complexity of the mu opioid receptor gene: alternative pre-mRNA splicing and promoters | Q36307818 |
| | Kappa opiate receptors localized by autoradiography to deep layers of cerebral cortex: relation to sedative effects | Q36312842 |
| | Pharmacogenetics of opioid receptors and addiction | Q36339767 |
| | Blockade of tolerance to morphine but not to kappa opioids by a nitric oxide synthase inhibitor | Q36341020 |
| | Opioid peptide-derived analgesics | Q36341669 |
| | Classification of multiple morphine and enkephalin binding sites in the central nervous system | Q36374248 |
| | Differentiation of delta and mu opiate receptor localizations by light microscopic autoradiography | Q36412585 |
| | Experimental artifacts and the analysis of ligand binding data: results of a computer simulation | Q36597472 |
| | mu opiate receptor: cDNA cloning and expression | Q36641338 |
| | Molecular cloning and functional analysis of the rat mu opioid receptor gene promoter | Q36671045 |
| | Cloning and characterization of the promoter region of the mouse μ opioid receptor gene | Q36691121 |
| | Six highly active mu-selective opioid peptides identified from two synthetic combinatorial libraries | Q36694071 |
| | Structure and chromosomal mapping of genes for the mouse kappa-opioid receptor and an opioid receptor homologue (MOR-C). | Q36710182 |
| | Expression of two variants of the human mu opioid receptor mRNA in SK-N-SH cells and human brain | Q36726539 |
| | The endomorphin system and its evolving neurophysiological role | Q36747911 |
| | cDNA cloning and regional distribution of a novel member of the opioid receptor family. | Q36747990 |
| | Molecular cloning and in situ hybridization histochemistry for rat mu-opioid receptor. | Q36750924 |
| | Molecular cloning and functional expression of a mu-opioid receptor from rat brain. | Q36771913 |
| | Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors | Q36773326 |
| | The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor | Q40079119 |
| | Mechanisms of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors | Q40094154 |
| | Autoradiographic localization of opiate receptors in rat brain. III. The telencephalon | Q40097547 |
| | Effects of exogenous and endogenous opiates on the hypothalamic--pituitary--gonadal axis in the male | Q40120253 |
| | Effects of perinatal 6-hydroxydopamine treatment on opiate receptor distribution in adult brain | Q40128551 |
| | Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters | Q40142289 |
| | Clinical review of parenteral meptazinol | Q40146781 |
| | Opiate binding to membrane preparations of neuroblastoma X glioma hybrid cells NG108-15: Effects of ions and nucleotides | Q40161278 |
| | Phospholipid changes in synaptic membranes by lipolytic enzymes and subsequent restoration of opiate binding with phosphatidylserine | Q40169934 |
| | Guanine nucleotides differentiate agonist and antagonist interactions with opiate receptors | Q40172836 |
| | Evidence for the involvement of cerebroside sulfate in opiate receptor binding: Studies with Azure A and jimpy mutant mice | Q40184780 |
| | Multiple opiate receptors. Enkephalins and morphine bind to receptors of different specificity | Q40217403 |
| | Stress responsivity, addiction, and a functional variant of the human mu-opioid receptor gene | Q40218031 |
| | Specific Nonopiate Receptors for β-Endorphin | Q40248072 |
| | Indirect evidence for presynaptic location of opiate receptors on chemosensitive primary sensory neurones | Q40269813 |
| | The opioid ligand binding of human mu-opioid receptor is modulated by novel splice variants of the receptor. | Q40297383 |
| | Receptor binding and pharmacological activity of opiates in the guinea-pig intestine | Q40334374 |
| | Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G. | Q40392922 |
| | A major species of mouse mu-opioid receptor mRNA and its promoter-dependent functional polyadenylation signal | Q40425400 |
| | Transcriptional regulation of mouse mu opioid receptor gene: Sp3 isoforms (M1, M2) function as repressors in neuronal cells to regulate the mu opioid receptor gene. | Q40460029 |
| | Heterodimerization of mu- and delta-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions. | Q40469699 |
| | Differential expression of mu-opioid receptor gene in CXBK and B6 mice by Sp1. | Q40488383 |
| | Molecular biology and pharmacology of cloned opioid receptors | Q40517576 |
| | Neuron-restrictive silencer factor (NRSF) functions as a repressor in neuronal cells to regulate the mu opioid receptor gene | Q40523640 |
| | Immunohistochemical study of the expression of exon11-containing mu opioid receptor variants in mouse brain | Q40533852 |
| | Constitutive activation of the mu opioid receptor by mutation of D3.49(164), but not D3.32(147): D3.49(164) is critical for stabilization of the inactive form of the receptor and for its expression. | Q40777582 |
| | A Nonpeptide Morphine-Like Compound: Immunocytochemical Localization in the Mouse Brain | Q40842257 |
| | Comparative immunohistochemical distributions of carboxy terminus epitopes from the mu-opioid receptor splice variants MOR-1D, MOR-1 and MOR-1C in the mouse and rat CNS. | Q40853885 |
| | Sigma receptor photolabeling and sigma receptor-mediated modulation of potassium channels in tumor cells | Q40947540 |
| | Controlling the pain of cancer | Q41029166 |
| | A chimeric analysis of the opioid receptor domains critical for the binding selectivity of mu opioid ligands | Q44345890 |
| | Antinociceptive effect of buprenorphine in mu1-opioid receptor deficient CXBK mice | Q44345988 |
| | Association of functional opioid receptor genotypes with alcohol dependence in Koreans | Q44346071 |
| | Autoradiographic analysis of mu1, mu2, and delta opioid binding in the central nervous system of C57BL/6BY and CXBK (opioid receptor-deficient) mice | Q44346460 |
| | Enhanced kappa-opioid receptor-mediated analgesia by antisense targeting the sigma1 receptor | Q44346672 |
| | Dimerization of the delta opioid receptor: implication for a role in receptor internalization | Q44347088 |
| | Opioid agonist and antagonist bivalent ligands. The relationship between spacer length and selectivity at multiple opioid receptors | Q44347161 |
| | Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden | Q44347200 |
| | A polymorphism of the mu-opioid receptor gene (OPRM1) and sensitivity to the effects of alcohol in humans | Q44347594 |
| | Opioid supraspinal analgesic synergy between the amygdala and periaqueductal gray in rats | Q44347964 |
| | Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain. | Q44348080 |
| | mu Opioid receptor knockout in mice: effects on ligand-induced analgesia and morphine lethality | Q44348420 |
| | Facilitation of μ-opioid receptor activity by preventing δ-opioid receptor-mediated codegradation. | Q44348937 |
| | Delta opioid receptor enhancement of mu opioid receptor-induced antinociception in spinal cord | Q44348974 |
| | Fentanyl and its analogs desensitize the cloned mu opioid receptor. | Q44348979 |
| | Association of polymorphisms in nicotinic acetylcholine receptor alpha 4 subunit gene (CHRNA4), mu-opioid receptor gene (OPRM1), and ethanol-metabolizing enzyme genes with alcoholism in Korean patients | Q44349048 |
| | Identification of four novel exon 5 splice variants of the mouse mu-opioid receptor gene: functional consequences of C-terminal splicing | Q44349269 |
| | The human mu opioid receptor gene: 5' regulatory and intronic sequences | Q44349281 |
| | Mu and kappa opioid receptors in periaqueductal gray and rostral ventromedial medulla | Q44349292 |
| | DAMGO recognizes four residues in the third extracellular loop to discriminate between mu- and kappa-opioid receptors | Q44349592 |
| | Opioid receptor gene expression in the rat brain during ontogeny, with special reference to the mesostriatal system: an in situ hybridization study | Q44349867 |
| | Differences in delta opioid receptor antinociception, binding, and mRNA levels between BALB/c and CXBK mice | Q44349886 |
| | No heroin or morphine 6beta-glucuronide analgesia in mu-opioid receptor knockout mice | Q44350077 |
| | Transcriptional regulation of mouse mu-opioid receptor gene | Q44350146 |
| | Characterization of the 3' untranslated region of the human mu-opioid receptor (MOR-1) mRNA. | Q44350206 |
| | The role of the mu(1) opioid receptor subtype in the regulation of prolactin and growth hormone secretion by Beta-endorphin in female rats: studies with naloxonazine | Q44350655 |
| | Opioid peptide receptor studies, 11: involvement of Tyr148, Trp318 and His319 of the rat mu-opioid receptor in binding of mu-selective ligands | Q44351724 |
| | Functional role of the spatial proximity of Asp114(2.50) in TMH 2 and Asn332(7.49) in TMH 7 of the mu opioid receptor | Q44351857 |
| | Expression of mu, kappa, and delta opioid receptor messenger RNA in the human CNS: a 33P in situ hybridization study | Q44352056 |
| | Meptazinol: a novel Mu-1 selective opioid analgesic | Q44352354 |
| | ASP147 in the third transmembrane helix of the rat mu opioid receptor forms ion-pairing with morphine and naltrexone | Q44352419 |
| | Identification and characterization of three new alternatively spliced mu-opioid receptor isoforms. | Q44352433 |
| | Opioid Receptors Undergo Axonal Flow | Q44352616 |
| | A novel opioid receptor site directed alkylating agent with irreversible narcotic antagonistic and reversible agonistic activities | Q44352732 |
| | Supraspinal and spinal delta(2) opioid receptor-mediated antinociceptive synergy is mediated by spinal alpha(2) adrenoceptors | Q44352873 |
| | Selective opioid delta agonists elicit antinociceptive supraspinal/spinal synergy in the rat. | Q44352974 |
| | Ontogeny of opioid pharmacology and receptors: High and low affinity site differences | Q44352975 |
| | Mutation of human mu opioid receptor extracellular "disulfide cysteine" residues alters ligand binding but does not prevent receptor targeting to the cell plasma membrane | Q44352984 |
| | Demonstration, characterization and localization of opioid binding sites in the midgut of the insectLeucophaea maderae (Blattaria) | Q44353257 |
| | Specific μ2 opioid isoreceptor regulation of nigrostriatal neurons: in vivo evidence with naloxonazine | Q44353461 |
| | Presence of a non-peptide morphine-like compound in human cerebrospinal fluid | Q44395553 |
| | Differential sensitivities of mouse strains to morphine and [Dmt1]DALDA analgesia | Q44438207 |
| | Clinical experience of long-term treatment with epidural and intrathecal opioids--a nationwide survey | Q44447841 |
| | Analgesic Synergy Between Topical Morphine and Butamben in Mice | Q44590528 |
| | Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice. | Q44653385 |
| | The synergistic analgesic interactions between hydrocodone and ibuprofen | Q44665999 |
| | Isolation, characterization and opiate activity of beta-endorphin from human pituitary glands | Q44803522 |
| | Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite. | Q44841016 |
| | Uptake of dihydromorphine-3H by synaptosomes | Q44961544 |
| | The development of morphine tolerance and dependence is associated with translocation of protein kinase C. | Q45080390 |
| | Isolation and expression of a novel alternatively spliced mu opioid receptor isoform, MOR-1F. | Q44330378 |
| | A very high affinity opioid binding site in rat brain: demonstration by computer modeling. | Q44330414 |
| | Intracisternal A-particle element in the 3' noncoding region of the mu-opioid receptor gene in CXBK mice: a new genetic mechanism underlying differences in opioid sensitivity | Q44330465 |
| | Differential distribution in rat brain of mu opioid receptor carboxy terminal splice variants MOR-1C-like and MOR-1-like immunoreactivity: evidence for region-specific processing | Q44330816 |
| | Antinociceptive interactions of opioid delta receptor agonists with morphine in mice: supra- and sub-additivity | Q44330959 |
| | Immunohistochemical labeling of the mu opioid receptor carboxy terminal splice variant mMOR-1B4 in the mouse central nervous system | Q44331040 |
| | Editorial: peptide and peptidomimetic ligands of opioid receptors | Q44331447 |
| | Role for the C-terminus in agonist-induced mu opioid receptor phosphorylation and desensitization | Q44331716 |
| | Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties | Q44331872 |
| | Selective opioid receptor agonist and antagonist displacement of [3H]naloxone binding in amphibian brain. | Q44331916 |
| | Immunohistochemical localization of the carboxy terminus of the novel mu opioid receptor splice variant MOR-1C within the human spinal cord | Q44332187 |
| | Chronic selective activation of excitatory opioid receptor functions in sensory neurons results in opioid 'dependence' without tolerance | Q44332228 |
| | Interaction of opioid peptides and other drugs with multiple kappa receptors in rat and human brain. Evidence for species differences | Q44332263 |
| | Allelic variation S268P of the human mu-opioid receptor affects both desensitization and G protein coupling. | Q44332395 |
| | Evidence for differential opioid mu 1- and mu 2-receptor-mediated regulation of heart rate in the conscious rat. | Q44332586 |
| | The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphine but not to kappa opioids | Q44332822 |
| | Cloning and expression of an isoform of the rat mu opioid receptor (rMOR1B) which differs in agonist induced desensitization from rMOR1. | Q44332928 |
| | delta-Opioid receptor immunoreactivity: distribution in brainstem and spinal cord, and relationship to biogenic amines and enkephalin | Q44332935 |
| | Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop | Q44332936 |
| | Double in situ hybridization study on coexistence of mu-, delta- and kappa-opioid receptor mRNAs with preprotachykinin A mRNA in the rat dorsal root ganglia | Q44333074 |
| | Identification of three mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon. | Q44333140 |
| | CNS levels of mu opioid receptor (MOR-1) mRNA during chronic treatment with morphine or naltrexone | Q44333421 |
| | Circuitry linking opioid-sensitive nociceptive modulatory systems in periaqueductal gray and spinal cord with rostral ventromedial medulla | Q44333502 |
| | Identification of the amino acid residues involved in selective agonist binding in the first extracellular loop of the δ‐ and μ‐opioid receptors | Q44333522 |
| | Quantitation of μ-opioid receptor (MOR-1) mRNA in selected regions of the rat CNS | Q44333646 |
| | Differential antagonism of opioid delta antinociception by [D-Ala2,Leu5,Cys6]enkephalin and naltrindole 5'-isothiocyanate: evidence for delta receptor subtypes | Q44333780 |
| | Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence | Q44333907 |
| | Selective blockage of delta opioid receptors prevents the development of morphine tolerance and dependence in mice | Q44333988 |
| | Antisense mapping the MOR‐1 opioid receptor: evidence for alternative splicing and a novel morphine‐6β‐glucuronide receptor | Q44334055 |
| | Immunohistochemical localization of the cloned μ opioid receptor in the rat CNS | Q44334260 |
| | Genetic influences in opioid analgesic sensitivity in mice | Q44334939 |
| | Chromosomal localization of opioid peptide and receptor genes in the mouse | Q44335046 |
| | An antisense oligodeoxynucleotide to mu-opioid receptors inhibits mu-opioid receptor agonist-induced analgesia in rats | Q44335172 |
| | Gender effects and central opioid analgesia | Q44335218 |
| | Characterization of the murine mu opioid receptor gene | Q44335341 |
| | Characterization of the cloned human mu opioid receptor. | Q44335441 |
| | Mu and delta opioid synergy between the periaqueductal gray and the rostro-ventral medulla | Q44336043 |
| | Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: an in situ hybridization study | Q44336066 |
| | Intracerebroventricular treatment with an antisense oligodeoxynucleotide to kappa-opioid receptors inhibited kappa-agonist-induced analgesia in rats | Q44336222 |
| | Antisense oligodeoxynucleotide to a delta-opioid receptor selectively blocks the spinal antinociception induced by delta-, but not mu- or kappa-opioid receptor agonists in the mouse | Q44336744 |
| | Presynaptic localization of the carboxy-terminus epitopes of the mu opioid receptor splice variants MOR-1C and MOR-1D in the superficial laminae of the rat spinal cord | Q44336857 |
| | Morphine-like drugs inhibit the stimulation of E prostaglandins of cyclic AMP formation by rat brain homogenate | Q45188803 |
| | Autoradiographic evaluation of the intracerebral distribution of 3H-etorphine in the mouse brain | Q45223987 |
| | FDA: No codeine after tonsillectomy for children | Q45753888 |
| | Toward better pain control. | Q45974355 |
| | Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: studies with selective sigma-1 ligands and sigma-1 knockout mice. | Q46046241 |
| | Autoradiographic localization of opiate κ-receptors in the guinea-pig brain | Q46411966 |
| | Comparison of effects of chronic administration of naloxone and naloxonazine upon food intake and maintainance of body weight in rats | Q47182287 |
| | Pharmacological characterization of buprenorphine, a mixed agonist-antagonist with kappa 3 analgesia | Q47803503 |
| | Stereospecific interaction of opiate narcotics in binding of 3H-dihydromorphine to membranes of rat brain | Q47929774 |
| | Role of mu 1-opiate receptors in supraspinal opiate analgesia: a microinjection study | Q48087419 |
| | Pharmacological characterization of morphine-6-sulfate and codeine-6-sulfate | Q48088054 |
| | Potentiation of morphine-induced mechanical antinociception by σ₁ receptor inhibition: role of peripheral σ₁ receptors. | Q48112821 |
| | Modulation of brainstem opiate analgesia in the rat by sigma 1 receptors: a microinjection study | Q48148180 |
| | Irreversible opiate agonists and antagonists: V. Hydrazone and acylhydrazone derivatives of naltrexone | Q48164459 |
| | Topical opioids in mice: analgesia and reversal of tolerance by a topical N-methyl-D-aspartate antagonist. | Q48178126 |
| | Inhibition of opiate tolerance by non-competitive N-methyl-D-aspartate receptor antagonists | Q48191134 |
| | Blockade of morphine analgesia by an antisense oligodeoxynucleotide against the mu receptor | Q48200149 |
| | Sex differences in supraspinal morphine analgesia are dependent on genotype. | Q48205262 |
| | Children's deaths linked with postsurgical codeine | Q48223212 |
| | More codeine fatalities after tonsillectomy in North American children | Q48249814 |
| | Analysis of lamprey and hagfish genes reveals a complex history of gene duplications during early vertebrate evolution | Q48285597 |
| | Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains | Q48313634 |
| | Ontogenetic development of [3H]naloxone binding in rat brain | Q48366271 |
| | Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section | Q48370690 |
| | Differential antagonism by naltrindole-5'-isothiocyanate on [3H]DSLET and [3H]DPDPE binding to striatal slices of mice | Q48380235 |
| | C fragment of lipotropin has a high affinity for brain opiate receptors | Q48392026 |
| | Genetic differences in morphine sensitivity, tolerance and withdrawal in rats | Q48394749 |
| | The contribution of the rostral ventromedial medulla to the antinociceptive effects of systemic morphine in restrained and unrestrained rats | Q48403354 |
| | Saturable binding of dihydromorphine and naloxone to rat brain tissue in vitro | Q48443532 |
| | Opiate receptors in mice: Genetic differences | Q48445636 |
| | A peptide-like substance from pituitary that acts like morphine. I. Isolation | Q48455187 |
| | Autoradiographic localization of the opiate receptor in rat brain | Q48455214 |
| | A peptide-like substance from pituitary that acts like morphine. 2. Purification and properties | Q48455254 |
| | An endogenous morphine-like factor in mammalian brain | Q48455261 |
| | Search for an Endogenous Ligand for the Opiate Receptor | Q48461778 |
| | Identification of novel high affinity opiate receptor binding in rat brain | Q48476166 |
| | Sites of morphine induced analgesia in the primate brain: relation to pain pathways | Q48506616 |
| | Localization of opiate receptor binding in synaptic membranes of rat brain | Q48564013 |
| | Opiate receptor binding: effects of enzymatic treatments | Q48578272 |
| | Somatostatin analogs with affinity for opiate receptors in rat brain binding assay | Q48583560 |
| | Opiate agonists and antagonists discriminated by receptor binding in brain | Q48611095 |
| | Distribution of stereospecific binding of the potent narcotic analgesic etorphine in the human brain: predominance in the limbic system | Q48621260 |
| | Regional distribution of opiate receptor binding in monkey and human brain | Q48624600 |
| | Tolerance to morphine analgesia: decreased multiplicative interaction between spinal and supraspinal sites | Q48634269 |
| | Localization in brain particulate fractions of narcotic analgesic drugs administered intracisternally to rats | Q48653267 |
| | New Methods for Characterization of Complex Receptor Systems Involving 3 or More Binding Sites: Application to Brain Opiate Receptors | Q48698448 |
| | The Membrane Binding of Morphine, Diphenylhydantoin, and Tetrahydrocannabinol | Q48711513 |
| | Antisense mapping DOR-1 in mice: further support for delta receptor subtypes | Q48730514 |
| | The d- and l-isomers of methadone bind to the non-competitive site on the N-methyl-D-aspartate (NMDA) receptor in rat forebrain and spinal cord | Q48800235 |
| | Analgesic activity and central nervous system distribution of the optical isomers of pentazocine in the rat | Q48820446 |
| | Multiple opiate receptor in human brain: an autoradiographic investigation | Q48840881 |
| | mu Opiate receptor immunoreactivity in rat central nervous system | Q48873819 |
| | Uptake of morphine in particulate fractions from rat brain | Q48876497 |
| | On the central sites for the antinociceptive action of morphine and fentanyl | Q48883196 |
| | Autoradiographic localization of kappa opiate receptors to deep layers of the cerebral cortex may explain unique sedative and analgesic effects | Q48896170 |
| | Morphine allosterically modulates the binding of [3H]leucine enkephalin to a particulate fraction of rat brain | Q48946685 |
| | Morphine Tolerance, Physical Dependence, and Synthesis of Brain 5-Hydroxytryptamine | Q49118851 |
| | Studies on the Intracellular Distribution and Tissue Binding of Dihydromorphine-7,8-H3 in the Rat | Q51235697 |
| | Analgesic synergy between topical lidocaine and topical opioids. | Q51374750 |
| | Different mu receptor subtypes mediate spinal and supraspinal analgesia in mice. | Q51748873 |
| | Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5]enkephalin in the mouse. | Q51791635 |
| | Epidural injections of bupivacaine, morphine, fentanyl, lofentanil, and DADL in chronically implanted rats: a pharmacologic and pathologic study. | Q51817917 |
| | Pharmacokinetic aspects of spinal morphine analgesia. | Q51849126 |
| | Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801 | Q52052445 |
| | MK-801 inhibits the development of morphine tolerance at spinal sites. | Q52222289 |
| | An opiate-receptor gene family reunion. | Q52271316 |
| | Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains. | Q52272626 |
| | Evidence for the Neuropeptide Cholecystokinin as an Antagonist of Opiate Analgesia | Q52282916 |
| | Pharmacologic basis for the increased sensitivity of the newborn rat to morphine. | Q52284012 |
| | Targeted disruption of the neuronal nitric oxide synthase gene. | Q52507290 |
| | Retention of heroin and morphine-6 beta-glucuronide analgesia in a new line of mice lacking exon 1 of MOR-1. | Q52534596 |
| | A new series of potent analgesics: dextro 2:2-diphenyl-3-methyl-4-morpholino-butyrylpyrrolidine and related amides. I. Chemical structure and pharmacological activity. | Q52774166 |
| | The analgesic effectiveness of nalorphine and nalorphine-morphine combinations in man. | Q52777160 |
| | Novel receptor mechanisms for heroin and morphine-6 beta-glucuronide analgesia. | Q53704453 |
| | A non-peptide morphine-like compound from brain. | Q53949881 |
| | Ontogeny of opiate mechanisms in relation to the sequential development of neurons known to be components of the guinea pig's enteric nervous system. | Q53961293 |
| | Synthetic and natural opiates interact with P-glycoprotein in multidrug-resistant cells. | Q54235431 |
| | Irreversible opiate agonists and antagonists. III. Phenylhydrazone derivatives of naloxone and oxymorphone. | Q54440894 |
| | Morphine-6-glucuronide, a potent mu agonist. | Q54659247 |
| | One or two genetic loci mediate high opiate analgesia in selectively bred mice. | Q54729949 |
| | Multiple opiate receptor sites on primary afferent fibres | Q55062437 |
| | Cellular site of opiate dependence. | Q55491038 |
| | Editorial | Q56990784 |
| | Primary structure of human β-lipotropin | Q59063086 |
| | Separation of morphine analgesia from physical dependence. | Q64925884 |
| | The specificity of binding of the narcotic agonist etorphine in synaptic membranes of rat brain in vivo | Q66684685 |
| | Different receptors mediate morphine-induced prolactin and growth hormone release | Q67269131 |
| | Dissociation of morphine's analgesic and respiratory depressant actions | Q67275124 |
| | NG-nitro-L-arginine prevents morphine tolerance | Q67575808 |
| | Lack of antinociceptive cross-tolerance between [D-Pen2, D-Pen5]enkephalin and [D-Ala2]deltorphin II in mice: evidence for delta receptor subtypes | Q68247858 |
| | The opiate receptor | Q68347936 |
| | Chemical characterization and regulation of endogenous morphine and codeine in the rat | Q68825239 |
| | Mediation of anorexia by human recombinant tumor necrosis factor through a peripheral action in the rat | Q69777332 |
| | Unidirectional analgesic cross-tolerance between morphine and levorphanol in the rat | Q69829488 |
| | Differential blockade by naloxonazine of two mu opiate actions: analgesia and inhibition of gastrointestinal transit | Q69835436 |
| | Studies in vivo with ICI 174864 and [D-Pen2, D-Pen5]enkephalin | Q70087300 |
| | Attenuation and reversal of morphine tolerance by the competitive N-methyl-D-aspartate receptor antagonist, LY274614 | Q70602366 |
| | Analgesic Effect of Morphine Glucuronides | Q70653923 |
| | Demonstration and Characterization of Opiate Inhibition of the Striatal Adenylate Cyclase | Q70800101 |
| | Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay | Q71082615 |
| | Absence of cross-tolerance to heroin in morphine-tolerant mice | Q71150038 |
| | (-)-Pentazocine analgesia in mice: interactions with a sigma receptor system | Q71489821 |
| | Sigma ligands indirectly modulate the NMDA receptor-ion channel complex on intact neuronal cells via sigma 1 site | Q71668817 |
| | Nitric oxide and opioid tolerance | Q71676259 |
| | Analgesic activity of tricyclic antidepressants | Q71700789 |
| | Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance | Q71804129 |
| | Multiplicative interaction between narcotic agonisms expressed at spinal and supraspinal sites of antinociceptive action as revealed by concurrent intrathecal and intracerebroventricular injections of morphine | Q71851330 |
| | Rat strain differences in the potentiation of morphine-induced analgesia by stress | Q72061429 |
| | Naloxazone, a long-acting opiate antagonist: effects on analgesia in intact animals and on opiate receptor binding in vitro | Q72428161 |
| | Mechanisms of hormone receptor-effector coupling: the beta-adrenergic receptor and adenylate cyclase | Q72532326 |
| | Long-acting opiate agonists and antagonists: 14-hydroxydihydromorphinone hydrazones | Q72612035 |
| | Synergistic brainstem interactions for morphine analgesia | Q72636203 |
| | A New Concept on the Mode of Interaction of Narcotic Analgesics with Receptors | Q72660536 |
| | Demonstration of stereospecific opiate binding in the nervous tissue of the marine mollusc Mytilus edulis | Q72842282 |
| | Mu-opiate receptor binding is up-regulated in mice selectively bred for high stress-induced analgesia | Q72861462 |
| | Selective localization of different types of opiate receptors in hippocampus as revealed by in vitro autoradiography | Q72881997 |
| | Opiate receptor ontogeny and morphine-induced effects: Influence of chronic footshock stress in preweanling rats | Q72901748 |
| | Naloxazone irreversibly inhibits the high affinity binding of [125I]D-ala2-D-leu5-enkephalin | Q72903604 |
| | Morphine in Cow and Human Milk: Could Dietary Morphine Constitute a Ligand for Specific Morphine (μ) Receptors? | Q72904212 |
| | Strain differences in opiate receptors in mouse brain | Q72911829 |
| | Ontogeny of opiate receptors in rat forebrain: visualization by in vitro autoradiography | Q72914391 |
| | Distribution of opiate receptors in the monkey brain: an autoradiographic study | Q72927530 |
| | Prolactin and growth hormone release by morphine in the rat: different receptor mechanisms | Q72938128 |
| | Opiate, enkephalin, and endorphin analgesia: relations to a single subpopulation of opiate receptors | Q72946024 |
| | Synergistic antinociceptive interactions of morphine and clonidine in rats with nerve-ligation injury | Q73016085 |
| | Antisense mapping: assessing functional significance of genes and splice variants | Q73190576 |
| | Spinal analgesic activity of orphanin FQ/nociceptin and its fragments | Q73195158 |
| | Increased brain P-glycoprotein in morphine tolerant rats | Q73426540 |
| | Synthetic analgesics: stereochemical considerations | Q73663111 |
| | Lack of morphine and enkephalin tolerance in 129/SvEv mice: evidence for a NMDA receptor defect | Q74138281 |
| | Morphine antinociception is enhanced in mdr1a gene-deficient mice | Q74216354 |
| | Analgesics and their antagonists: some steric and chemical considerations. I. The dissociation constants of some tertiary amines and synthetic analgesics, the conformations of methadone-type compounds | Q74258500 |
| | Analgesics and their antagonists: some steric and chemical considerations. II. The influence of the basic group on physico-chemical properties and the activity of methadone and thiambutene-type compounds | Q74258504 |
| | Analgesics and their antagonists: some steric and chemical considerations. III. The influence of the basic group on the biological response | Q74258509 |
| | Genetic variance in nociception and its relationship to the potency of morphine-induced analgesia in thermal and chemical tests | Q74435399 |
| | Spinal antinociceptive synergism between morphine and clonidine persists in mice made acutely or chronically tolerant to morphine | Q74459769 |
| | Inhibition of the peristaltic reflex of the isolated guinea-pig ileum | Q74497983 |
| | Methadone analgesia in morphine-insensitive CXBK mice | Q74828238 |
| | Acute morphine dependence in mice selectively-bred for high and low analgesia | Q77684360 |
| | CENTRAL NERVOUS SYSTEM DISTRIBUTION AND METABOLISM OF C-14-MORPHINE DURING MORPHINE-INDUCED FELINE MANIA | Q78512387 |
| | Compounds Related to Pethidine--II. Mannich Bases Derived from Various Esters of 4-Carboxy-4-phenylpiperidine and Acetophenones | Q78784255 |
| | Narcotic antagonists as analgesics | Q79335988 |
| | On the contraction of muscle, chiefly in relation to the presence of ;receptive' substances: Part IV. The effect of curari and of some other substances on the nicotine response of the sartorius and gastrocnemius muscles of the frog | Q80322201 |
| | Pain in Men Wounded in Battle | Q81262005 |
| | The role of protein synthesis inhibition in the prevention of morphine tolerance | Q95781298 |
| P433 | issue | 4 | |
| P921 | main subject | opioid | Q427523 |
| P304 | page(s) | 1257-1317 | |
| P577 | publication date | 2013-09-27 | |
| P1433 | published in | Pharmacological Reviews | Q2085079 |
| P1476 | title | Mu opioids and their receptors: evolution of a concept | |
| P478 | volume | 65 | |