scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0014-2999(01)00968-2 |
P698 | PubMed publication ID | 11426838 |
P2093 | author name string | W D Bowen | |
M J Friedman | |||
B R De Costa | |||
R R Matsumoto | |||
B Pouw | |||
K A McCracken | |||
P2860 | cites work | Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene | Q24336001 |
Differentiation of sigma ligand-activated receptor subtypes that modulate NMDA-evoked [3H]-noradrenaline release in rat hippocampal slices | Q24674608 | ||
Prevention of cocaine-induced convulsions and lethality in mice: effectiveness of targeting different sites on the NMDA receptor complex | Q28372018 | ||
Two novel sigma receptor ligands, BD1047 and LR172, attenuate cocaine-induced toxicity and locomotor activity | Q28376445 | ||
Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference | Q31440672 | ||
N-alkyl substituted analogs of the sigma receptor ligand BD1008 and traditional sigma receptor ligands affect cocaine-induced convulsions and lethality in mice | Q31869459 | ||
Cloning and characterization of a mouse sigma1 receptor. | Q32062674 | ||
Cloning and functional characterization of a sigma receptor from rat brain. | Q32104855 | ||
Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor | Q32152197 | ||
Pharmacotherapies for treatment of cocaine abuse: preclinical aspects | Q33698691 | ||
Intracellular sigma1 receptor modulates phospholipase C and protein kinase C activities in the brainstem | Q36418374 | ||
Focal stimulation of specific pathways in the rat hippocampus causes a reduction in radioligand binding to the haloperidol-sensitive sigma receptor | Q41135178 | ||
Cocaine-induced convulsions: pharmacological antagonism at serotonergic, muscarinic and sigma receptors | Q42550669 | ||
Characterization of two novel sigma receptor ligands: antidystonic effects in rats suggest sigma receptor antagonism | Q42557456 | ||
Enhanced kappa-opioid receptor-mediated analgesia by antisense targeting the sigma1 receptor | Q44346672 | ||
Endogenous ligands for sigma opioid receptors in the brain ("sigmaphin"): evidence from binding assays | Q44346851 | ||
Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the .sigma. receptor | Q45172168 | ||
Effects of sigma ligands on mouse cerebellar cyclic guanosine monophosphate (cGMP) levels in vivo: further evidence for a functional modulation ofN-methyl-d-aspartate (NMDA) receptor complex-mediated events by sigma ligands | Q46797536 | ||
Synthesis and biological evaluation of conformationally restricted 2-(1-pyrrolidinyl)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methylethylenediam ines as sigma receptor ligands. 1. Pyrrolidine, piperidine, homopiperidine, and tetrahydroisoquinoline classes | Q46870429 | ||
Novel sigma receptor ligands attenuate the locomotor stimulatory effects of cocaine | Q46887506 | ||
Microinjection of sigma ligands into cranial nerve nuclei produces vacuous chewing in rats | Q47964892 | ||
Relationship between modulation of the cerebellorubrospinal system in the in vitro turtle brain and changes in motor behavior in rats: effects of novel sigma ligands | Q48184423 | ||
Increases in rat striatal extracellular dopamine and vacuous chewing produced by two sigma receptor ligands | Q48332705 | ||
(+)-6,7-Benzomorphan sigma ligands stimulate dopamine synthesis in rat corpus striatum tissue | Q48670734 | ||
Sigma receptors modulate both A9 and A10 dopaminergic neurons in the rat brain: functional interaction with NMDA receptors | Q48919860 | ||
Regulation of [3H] dopamine release from mesolimbic and mesocortical areas of guinea pig brain by sigma receptors | Q48967994 | ||
Drug specificity of pharmacological dystonia | Q48987709 | ||
Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice. | Q51384162 | ||
Cocaine toxicity: concurrent influence of dopaminergic, muscarinic and sigma receptors in mediating cocaine-induced lethality. | Q51548621 | ||
Model for estimating dopamine transporter occupancy and subsequent increases in synaptic dopamine using positron emission tomography and carbon-11-labeled cocaine. | Q51550172 | ||
Evidence for an involvement of muscarinic cholinergic systems in the induction but not expression of behavioral sensitization to cocaine. | Q51561345 | ||
Stimulation of rat striatal tyrosine hydroxylase activity following intranigral administration of sigma receptor ligands. | Q51610642 | ||
Selective sigma ligands block stimulant effects of cocaine. | Q51707499 | ||
Modulation of the lethal effects of cocaine by cholinomimetics. | Q51760672 | ||
Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling. | Q55065614 | ||
A proposal for the classification of sigma binding sites | Q67487993 | ||
Synthesis and receptor binding of enantiomeric N-substituted cis-N-[2-(3,4-dichlorophenyl)ethyl]-2-(1-pyrrolidinyl)cyclohexylamines as high-affinity .sigma. receptor ligands | Q68257707 | ||
Sigma receptors regulate contractions of the guinea pig ileum longitudinal muscle/myenteric plexus preparation elicited by both electrical stimulation and exogenous serotonin | Q69357244 | ||
sigma2 Site-mediated inhibition of electrically evoked guinea pig ileum longitudinal muscle/myenteric plexus contractions | Q71377110 | ||
Sigma ligands indirectly modulate the NMDA receptor-ion channel complex on intact neuronal cells via sigma 1 site | Q71668817 | ||
A comparison of (-)-deoxybenzomorphans devoid of opiate activity with their dextrorotatory phenolic counterparts suggests role of sigma 2 receptors in motor function | Q72954030 | ||
P433 | issue | 2-3 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 163-74 | |
P577 | publication date | 2001-05-11 | |
P1433 | published in | European Journal of Pharmacology | Q1376712 |
P1476 | title | Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice | |
P478 | volume | 419 |
Q44363687 | 1,4-dibenzylpiperazines possess anticocaine activity |
Q35197016 | A Role for Sigma Receptors in Stimulant Self Administration and Addiction. |
Q24611779 | A novel substituted piperazine, CM156, attenuates the stimulant and toxic effects of cocaine in mice |
Q43450779 | A selective sigma-2 receptor ligand antagonizes cocaine-induced hyperlocomotion in mice. |
Q34813687 | Activation of σ-receptors induces binge-like drinking in Sardinian alcohol-preferring rats |
Q58764798 | Behavioral Effects of a Potential Novel TAAR1 Antagonist |
Q44438024 | Behavioral effects of rimcazole analogues alone and in combination with cocaine |
Q50323703 | Cocaine Effects on Dopaminergic Transmission Depend on a Balance between Sigma-1 and Sigma-2 Receptor Expression |
Q27325489 | Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers |
Q36494168 | Cocaine occupancy of sigma1 receptors and dopamine transporters in mice |
Q35429841 | Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors |
Q34276531 | Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine |
Q40235215 | Dopamine-1 receptor agonist, but not cocaine, modulates sigma(1) gene expression in SVG cells |
Q36870910 | Effects of the selective sigma receptor ligand, 1-(2-phenethyl)piperidine oxalate (AC927), on the behavioral and toxic effects of cocaine |
Q28215345 | Involvement of sigma receptors in the behavioral effects of cocaine: evidence from novel ligands and antisense oligodeoxynucleotides |
Q36883121 | Lack of cocaine-like discriminative-stimulus effects of σ-receptor agonists in rats. |
Q47353437 | Novel Sigma-1 receptor antagonists: from opioids to small molecules: what is new? |
Q37107339 | Pharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo. |
Q37545379 | Pharmacology and therapeutic potential of sigma(1) receptor ligands |
Q24656937 | Reinforcing effects of sigma-receptor agonists in rats trained to self-administer cocaine |
Q35673122 | Review of the pharmacological and clinical profile of rimcazole. |
Q28202676 | Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters |
Q36610032 | Self-administration of cocaine induces dopamine-independent self-administration of sigma agonists. |
Q39185737 | Sigma Receptors and Substance Use Disorders |
Q39790990 | Sigma ligands, but not N-methyl-D-aspartate antagonists, reduce levodopa-induced dyskinesias |
Q28266963 | Sigma receptors: biology and therapeutic potential |
Q28208121 | Sigma receptors: potential medications development target for anti-cocaine agents |
Q34804462 | Sigma(1) (sigma(1)) receptor antagonists represent a new strategy against cocaine addiction and toxicity |
Q87462009 | Sigma-1 receptor inhibition reverses acute inflammatory hyperalgesia in mice: role of peripheral sigma-1 receptors |
Q30546325 | Stimulants as specific inducers of dopamine-independent σ agonist self-administration in rats |
Q28204130 | Synthesis of Chiral 1-[ω-(4-Chlorophenoxy)alkyl]-4-methylpiperidines and Their Biological Evaluation at σ1, σ2, and Sterol Δ8−Δ7 Isomerase Sites |
Q42700435 | The Sigma-2 Receptor Selective Agonist Siramesine (Lu 28-179) Decreases Cocaine-Reinforced Pavlovian Learning and Alters Glutamatergic and Dopaminergic Input to the Striatum |
Q24658287 | The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking |
Q42244347 | Trifluoromethoxyl substituted phenylethylene diamines as high affinity sigma receptor ligands with potent anti-cocaine actions |
Q35920289 | dextro-Morphine attenuates the morphine-produced conditioned place preference via the sigma(1) receptor activation in the rat. |
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