Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice

scientific article (publication date: 11 May 2001)

Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0014-2999(01)00968-2
P698PubMed publication ID11426838

P2093author name stringW D Bowen
M J Friedman
B R De Costa
R R Matsumoto
B Pouw
K A McCracken
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N-alkyl substituted analogs of the sigma receptor ligand BD1008 and traditional sigma receptor ligands affect cocaine-induced convulsions and lethality in miceQ31869459
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Focal stimulation of specific pathways in the rat hippocampus causes a reduction in radioligand binding to the haloperidol-sensitive sigma receptorQ41135178
Cocaine-induced convulsions: pharmacological antagonism at serotonergic, muscarinic and sigma receptorsQ42550669
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Effects of sigma ligands on mouse cerebellar cyclic guanosine monophosphate (cGMP) levels in vivo: further evidence for a functional modulation ofN-methyl-d-aspartate (NMDA) receptor complex-mediated events by sigma ligandsQ46797536
Synthesis and biological evaluation of conformationally restricted 2-(1-pyrrolidinyl)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methylethylenediam ines as sigma receptor ligands. 1. Pyrrolidine, piperidine, homopiperidine, and tetrahydroisoquinoline classesQ46870429
Novel sigma receptor ligands attenuate the locomotor stimulatory effects of cocaineQ46887506
Microinjection of sigma ligands into cranial nerve nuclei produces vacuous chewing in ratsQ47964892
Relationship between modulation of the cerebellorubrospinal system in the in vitro turtle brain and changes in motor behavior in rats: effects of novel sigma ligandsQ48184423
Increases in rat striatal extracellular dopamine and vacuous chewing produced by two sigma receptor ligandsQ48332705
(+)-6,7-Benzomorphan sigma ligands stimulate dopamine synthesis in rat corpus striatum tissueQ48670734
Sigma receptors modulate both A9 and A10 dopaminergic neurons in the rat brain: functional interaction with NMDA receptorsQ48919860
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Drug specificity of pharmacological dystoniaQ48987709
Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice.Q51384162
Cocaine toxicity: concurrent influence of dopaminergic, muscarinic and sigma receptors in mediating cocaine-induced lethality.Q51548621
Model for estimating dopamine transporter occupancy and subsequent increases in synaptic dopamine using positron emission tomography and carbon-11-labeled cocaine.Q51550172
Evidence for an involvement of muscarinic cholinergic systems in the induction but not expression of behavioral sensitization to cocaine.Q51561345
Stimulation of rat striatal tyrosine hydroxylase activity following intranigral administration of sigma receptor ligands.Q51610642
Selective sigma ligands block stimulant effects of cocaine.Q51707499
Modulation of the lethal effects of cocaine by cholinomimetics.Q51760672
Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling.Q55065614
A proposal for the classification of sigma binding sitesQ67487993
Synthesis and receptor binding of enantiomeric N-substituted cis-N-[2-(3,4-dichlorophenyl)ethyl]-2-(1-pyrrolidinyl)cyclohexylamines as high-affinity .sigma. receptor ligandsQ68257707
Sigma receptors regulate contractions of the guinea pig ileum longitudinal muscle/myenteric plexus preparation elicited by both electrical stimulation and exogenous serotoninQ69357244
sigma2 Site-mediated inhibition of electrically evoked guinea pig ileum longitudinal muscle/myenteric plexus contractionsQ71377110
Sigma ligands indirectly modulate the NMDA receptor-ion channel complex on intact neuronal cells via sigma 1 siteQ71668817
A comparison of (-)-deoxybenzomorphans devoid of opiate activity with their dextrorotatory phenolic counterparts suggests role of sigma 2 receptors in motor functionQ72954030
P433issue2-3
P407language of work or nameEnglishQ1860
P304page(s)163-74
P577publication date2001-05-11
P1433published inEuropean Journal of PharmacologyQ1376712
P1476titleConformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice
P478volume419

Reverse relations

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