Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma.

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Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1084132533
P356DOI10.1038/SREP44653
P932PMC publication ID5356346
P698PubMed publication ID28304380

P50authorMichael S. TorbensonQ106615136
Rondell P GrahamQ48088845
P2093author name stringPraveen Sethupathy
Lola M Reid
Tsunekazu Oikawa
Mengjie Chen
Eliane Wauthier
Grace O Silva
Eva C M Vitucci
Kevin G Greene
Wendy A Pitman
Timothy A Dinh
P2860cites workDifferential expression analysis for sequence count dataQ21184103
Antitumor efficacy of a monoclonal antibody that inhibits the activity of cancer-associated carbonic anhydrase XII.Q51785175
mTORC1 and FGFR1 signaling in fibrolamellar hepatocellular carcinomaQ54345071
Fibrolamellar carcinoma of the liver: A tumor of adolescents and young adults with distinctive clinico-pathologic featuresQ72855415
Clinicopathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma with and without cirrhosisQ81791423
Epidermal growth factor receptor expression and gene copy number in fibrolamellar hepatocellular carcinomaQ82971565
The best immunohistochemical panel for differentiating hepatocellular carcinoma from metastatic adenocarcinomaQ84073513
Fibrolamellar hepatocellular carcinoma: an immunohistochemical comparison with conventional hepatocellular carcinomaQ84161346
C6orf176: a novel possible regulator of cAMP-mediated gene expressionQ24298149
Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteinsQ24308079
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasisQ24607308
Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancersQ24651144
Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinomaQ27852915
Unique genomic profile of fibrolamellar hepatocellular carcinomaQ27853116
DNAJB1-PRKACA is specific for fibrolamellar carcinoma.Q27853135
Carbonic anhydrases: novel therapeutic applications for inhibitors and activatorsQ28263238
p21-Activated kinase 3 is overexpressed in thymic neuroendocrine tumors (carcinoids) with ectopic ACTH syndrome and participates in cell migrationQ28296152
Neuroendocrine-specific expression of the human prohormone convertase 1 gene. Hormonal regulation of transcription through distinct cAMP response elementsQ28304253
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genomeQ29547458
Circular binary segmentation for the analysis of array-based DNA copy number dataQ29615406
Hepatocellular carcinomaQ29615765
TANRIC: An Interactive Open Platform to Explore the Function of lncRNAs in CancerQ30488162
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Inferring tumour purity and stromal and immune cell admixture from expression dataQ30674996
Fibrolamellar hepatocellular carcinoma in the USA, 2000-2010: A detailed report on frequency, treatment and outcome based on the Surveillance, Epidemiology, and End Results databaseQ33695465
Fibrolamellar carcinomas are positive for CD68Q33757399
MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes.Q34077389
MapSplice: accurate mapping of RNA-seq reads for splice junction discovery.Q34189334
The genomic landscape of fibrolamellar hepatocellular carcinoma: whole genome sequencing of ten patients.Q34458870
Outcome of patients with fibrolamellar hepatocellular carcinoma.Q34494031
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Genomic analysis of fibrolamellar hepatocellular carcinomaQ34673400
The functional role of long non-coding RNA in human carcinomasQ34995156
Structural insights into mis-regulation of protein kinase A in human tumors.Q35062811
High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinomaQ35114504
RNA-mediated epigenetic regulation of gene expressionQ35223649
The epidemiology of cholangiocarcinomaQ35802314
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Inhibition of miR-29 has a significant lipid-lowering benefit through suppression of lipogenic programs in liverQ35922081
Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cellsQ36145871
Transcriptomic characterization of fibrolamellar hepatocellular carcinomaQ36268536
Systematic pan-cancer analysis of tumour purityQ36350773
Comprehensive Molecular Characterization of Papillary Renal-Cell CarcinomaQ36642291
Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers.Q36649171
Non-coding RNA LINC00473 mediates decidualization of human endometrial stromal cells in response to cAMP signalingQ36656860
cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth.Q36951807
KEA: kinase enrichment analysisQ37109842
Fibrolamellar carcinoma: 2012 updateQ37288706
Anterior gradient-2 is overexpressed by fibrolamellar carcinomasQ37352343
Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinomaQ37408965
Prognostic indicators and treatment outcome in 94 cases of fibrolamellar hepatocellular carcinomaQ37553809
Fibrolamellar Carcinoma: A Review with Focus on Genetics and Comparison to Other Malignant Primary Liver TumorsQ37846146
Interfering with pH regulation in tumours as a therapeutic strategyQ37933052
Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line.Q38307214
Stemness characteristics of fibrolamellar hepatocellular carcinoma: immunohistochemical analysis with comparisons to conventional hepatocellular carcinoma.Q38416844
Unique features of long non-coding RNA biogenesis and functionQ38668939
Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors.Q39450874
Carbonic anhydrase XII promotes invasion and migration ability of MDA-MB-231 breast cancer cells through the p38 MAPK signaling pathwayQ39708680
Molecular characteristics of fibrolamellar hepatocellular carcinoma.Q40055042
FGFR1 and FGFR2 in fibrolamellar carcinomaQ40640497
Inhibition of cyclic AMP-dependent induction of ornithine aminotransferase by simple carbohydrates in cultured hepatocytesQ42200177
New targets of beta-catenin signaling in the liver are involved in the glutamine metabolismQ44226601
Transcriptional analysis of the human ornithine aminotransferase promoterQ44314585
Transcriptional profiling of pure fibrolamellar hepatocellular carcinoma reveals an endocrine signature.Q46688979
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesDESeq2Q113018293
P407language of work or nameEnglishQ1860
P921main subjectThe Cancer Genome AtlasQ3979425
non-coding RNAQ427087
RNA analysisQ95588220
P304page(s)44653
P577publication date2017-03-17
P1433published inScientific ReportsQ2261792
P1476titleComprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma
P478volume7

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cites work (P2860)
Q64280822An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma
Q47635386CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma.
Q48201057CRTC1-MAML2 fusion-induced lncRNA LINC00473 expression maintains the growth and survival of human mucoepidermoid carcinoma cells
Q42367909Comprehensive analysis of long non-coding RNA PVT1 gene interaction regulatory network in hepatocellular carcinoma using gene microarray and bioinformatics
Q47377422DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma.
Q89898304DnaJ-PKAc fusion induces liver inflammation in a zebrafish model of Fibrolamellar Carcinoma
Q54117733Driver Fusions and Their Implications in the Development and Treatment of Human Cancers
Q47312923Fibrolamellar Carcinoma in the Carney Complex: PRKAR1A Loss Instead of the Classic DNAJB1-PRKACA Fusion.
Q52689575Fibrolamellar Carcinoma: Recent Advances and Unresolved Questions on the Molecular Mechanisms
Q64882814Hyperammonemic encephalopathy in a patient with fibrolamellar hepatocellular carcinoma: case report and literature review.
Q58708035LINC00473 promotes the Taxol resistance via miR-15a in colorectal cancer
Q41670848Liver Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells
Q47150980Long non‑coding RNA HOTTIP promotes hepatocellular carcinoma tumorigenesis and development: A comprehensive investigation based on bioinformatics, qRT‑PCR and meta‑analysis of 393 cases
Q92366663Long non‑coding RNA LINC00473/miR‑195‑5p promotes glioma progression via YAP1‑TEAD1‑Hippo signaling
Q64230086MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar Carcinoma
Q97551598Molecular profiling and analysis of genetic aberrations aimed at identifying potential therapeutic targets in fibrolamellar carcinoma of the liver
Q52657106Non coding RNA analysis in fibrolamellar hepatocellular carcinoma
Q92816722Phytochemicals as Modulators of Long Non-Coding RNAs and Inhibitors of Cancer-Related Carbonic Anhydrases
Q92618325Prognostic value of carbonic anhydrase XII (CA XII) overexpression in hepatocellular carcinoma
Q61805289Road map for fibrolamellar carcinoma: progress and goals of a diversified approach
Q55472607TIMP2 is a Poor Prognostic Factor and Predicts Metastatic Biological Behavior in Gastric Cancer.

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