Approaches for targeting cancer stem cells drug resistance

scientific article

Approaches for targeting cancer stem cells drug resistance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/17460441.2016.1243525
P698PubMed publication ID27700193

P2093author name stringSabino De Placido
Roberto Bianco
Roberta Rosa
Valentina D'Amato
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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotypeQ29615563
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Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cellsQ33971668
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Hedgehog Signaling Antagonist GDC-0449 (Vismodegib) Inhibits Pancreatic Cancer Stem Cell Characteristics: Molecular MechanismsQ34075584
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Epigenetic targeting of ovarian cancer stem cellsQ34135466
Merlin deficiency predicts FAK inhibitor sensitivity: a synthetic lethal relationshipQ34193347
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A phase I dose escalation and expansion study of the anticancer stem cell agent demcizumab (anti-DLL4) in patients with previously treated solid tumors.Q34443946
Ovarian cancer stem cells express ROR1, which can be targeted for anti-cancer-stem-cell therapyQ34448718
CD73 is associated with poor prognosis in high-grade serous ovarian cancerQ38835904
Twist1 and Snail link Hedgehog signaling to tumor-initiating cell-like properties and acquired chemoresistance independently of ABC transportersQ38920037
MiR-200c suppresses TGF-β signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF217 and ZEB1 in breast cancerQ39016680
CD133+ cancer stem-like cells in small cell lung cancer are highly tumorigenic and chemoresistant but sensitive to a novel neuropeptide antagonistQ39033543
Phosphoproteomic profiling identifies focal adhesion kinase as a mediator of docetaxel resistance in castrate-resistant prostate cancerQ39066733
Acquisition of epithelial-mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistanceQ39070920
Brief report: The lincRNA Hotair is required for epithelial-to-mesenchymal transition and stemness maintenance of cancer cell linesQ39097543
Calyxin Y induces hydrogen peroxide-dependent autophagy and apoptosis via JNK activation in human non-small cell lung cancer NCI-H460 cellsQ39133347
Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch- and hedgehog-dependent tumor-initiating cells.Q39279366
ERK1/2 Regulation of CD44 Modulates Oral Cancer AggressivenessQ39442395
Metformin against TGFβ-induced epithelial-to-mesenchymal transition (EMT): from cancer stem cells to aging-associated fibrosis.Q39630008
Kinome profiling in pediatric brain tumors as a new approach for target discoveryQ39830889
Cancer/testis antigens can be immunological targets in clonogenic CD133+ melanoma cells.Q39883131
MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1.Q39996214
Measurement of interaction between antiprotonsQ40357137
PI3K/Akt/mTOR pathway dual inhibitor BEZ235 suppresses the stemness of colon cancer stem cells.Q40509393
Phase II randomized trial comparing sequential first-line everolimus and second-line sunitinib versus first-line sunitinib and second-line everolimus in patients with metastatic renal cell carcinomaQ41508355
Tackling the cancer stem cells - what challenges do they pose?Q34523263
Suppression of cancer relapse and metastasis by inhibiting cancer stemnessQ35090120
Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinomaQ35117549
MiR-124 Radiosensitizes human colorectal cancer cells by targeting PRRX1Q35140218
Down-regulation of miR-223 reverses epithelial-mesenchymal transition in gemcitabine-resistant pancreatic cancer cellsQ35176428
Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cellsQ35176432
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Cancer stem-like sphere cells induced from de-differentiated hepatocellular carcinoma-derived cell lines possess the resistance to anti-cancer drugsQ35280672
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MUC1 immunobiology: from discovery to clinical applicationsQ35671712
Inhibition of Hedgehog signalling by NVP-LDE225 (Erismodegib) interferes with growth and invasion of human renal cell carcinoma cellsQ35678417
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TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse.Q36057591
TGF-β inhibition enhances chemotherapy action against triple-negative breast cancerQ36638173
Overexpression of PD2 leads to increased tumorigenicity and metastasis in pancreatic ductal adenocarcinomaQ36772125
The sonic hedgehog signaling network in development and neoplasiaQ36918590
Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathwayQ37134040
Src and focal adhesion kinase as therapeutic targets in cancerQ37215683
Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.Q37320359
Normal stem cells and cancer stem cells: similar and differentQ37740620
TGF-β/TGF-β receptor system and its role in physiological and pathological conditions.Q37880150
Dysregulation of Wnt/β-Catenin Signaling in Gastrointestinal CancersQ37966605
The developing cancer stem-cell model: clinical challenges and opportunitiesQ37980960
Regulation of EMT by Notch signaling pathway in tumor progressionQ38156210
Therapeutic modulation of Notch signalling--are we there yet?Q38208211
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Targeting RAS-ERK signalling in cancer: promises and challengesQ38272894
Targeting microRNAs in epithelial-to-mesenchymal transition-induced cancer stem cells: therapeutic approaches in cancerQ38309242
Clusterin Mediates TGF-β–Induced Epithelial–Mesenchymal Transition and Metastasis via Twist1 in Prostate Cancer CellsQ38322593
Cyclin D1 is a direct target of JAG1-mediated Notch signaling in breast cancerQ38348851
A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortiaQ38387402
Binding interactions between long noncoding RNA HOTAIR and PRC2 proteinsQ38483070
Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial.Q38485521
CYLD regulates keratinocyte differentiation and skin cancer progression in humans.Q38626355
An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells.Q38785671
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectneoplastic stem cellsQ1638475
P304page(s)1201-1212
P577publication date2016-10-04
P13046publication type of scholarly workreview articleQ7318358
P1433published inExpert Opinion on Drug DiscoveryQ5421204
P1476titleApproaches for targeting cancer stem cells drug resistance
P478volume11

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cites work (P2860)
Q90737495Clinical significance of a pvrl 4 encoded gene Nectin-4 in metastasis and angiogenesis for tumor relapse
Q52721498Current Opinions on Chemoresistance: An Overview
Q41352333Gene Expression Profiling of Hepatocellular Carcinoma Derived Cancer Stem Like Cell under Hypoxia.
Q42135646Inhibition of HAX-1 by miR-125a reverses cisplatin resistance in laryngeal cancer stem cells
Q46262914Naphthoquinones: A continuing source for discovery of therapeutic antineoplastic agents.
Q58719363Optimizing poly (ADP-ribose) polymerase inhibition through combined epigenetic and immunotherapy
Q89638333Quantitative site- and structure-specific N-glycoproteomics characterization of differential N-glycosylation in MCF-7/ADR cancer stem cells
Q61816938Selected Office Based Anticancer Treatment Strategies
Q92134544The Role of Exosomal microRNA in Cancer Drug Resistance

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