GSK3 protein positively regulates type I insulin-like growth factor receptor through forkhead transcription factors FOXO1/3/4

scientific article

GSK3 protein positively regulates type I insulin-like growth factor receptor through forkhead transcription factors FOXO1/3/4 is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M114.580738
P932PMC publication ID4155645
P698PubMed publication ID25053419

P2093author name stringJiao Wang
Shu Liu
Ting Luo
Hui Hua
Qingbin Kong
Ting Shao
Xiaodong Huo
Yangfu Jiang
P2860cites workAkt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factorQ22009126
GSK-3: tricks of the trade for a multi-tasking kinaseQ24624069
The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptorQ24682781
Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeuticsQ24685475
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase BQ27860731
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanismQ28114789
Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor geneQ28118453
Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic diseaseQ28218236
GSK3-mediated BCL-3 phosphorylation modulates its degradation and its oncogenicityQ42824819
High FOXO3a expression is associated with a poorer prognosis in AML with normal cytogenetics.Q47758619
GSK3β regulates gluconeogenic gene expression through HNF4α and FOXO1.Q51360193
Kinase-inactive glycogen synthase kinase 3beta promotes Wnt signaling and mammary tumorigenesis.Q53356648
From worm to human: bioinformatics approaches to identify FOXO target genesQ81176620
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growthQ28262401
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasisQ28285131
Control of cyclin G2 mRNA expression by forkhead transcription factors: novel mechanism for cell cycle control by phosphoinositide 3-kinase and forkheadQ28506168
GSK-3-mediated phosphorylation enhances Maf-transforming activityQ28576703
The renaissance of GSK3Q29616725
FOXOs, cancer and regulation of apoptosisQ33642512
Transcriptional feedback control of insulin receptor by dFOXO/FOXO1.Q34084120
AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemiasQ34212654
Down-regulation of cyclin G2 by insulin, IGF-I (insulin-like growth factor 1) and X10 (AspB10 insulin): role in mitogenesisQ34372865
GSK3 takes centre stage more than 20 years after its discoveryQ34374129
AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activityQ34511038
Glycogen synthase kinase-3β, NF-κB signaling, and tumorigenesis of human osteosarcoma.Q34637826
A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expressionQ34656781
Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferationQ35571394
Inhibition of PI3K/mTOR leads to adaptive resistance in matrix-attached cancer cellsQ35816378
Regulation of cell cycle progression by forkhead transcription factor FOXO3 through its binding partner DNA replication factor Cdt1.Q35889450
MafA stability in pancreatic beta cells is regulated by glucose and is dependent on its constitutive phosphorylation at multiple sites by glycogen synthase kinase 3.Q36176619
Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene productQ36378010
GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers.Q36512934
Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptorQ36696132
Dynamic FoxO transcription factorsQ36889897
Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation.Q37001651
Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generationQ37106907
Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapyQ37163149
The PKB/FOXO switch in aging and cancerQ37871660
AKT down-regulates insulin-like growth factor-1 receptor as a negative feedbackQ39535703
TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemiaQ39744014
Role of cyclic AMP response element-binding protein in insulin-like growth factor-i receptor up-regulation by sex steroids in prostate cancer cellsQ39801970
FOXO transcription factors enforce cell cycle checkpoints and promote survival of hematopoietic cells after DNA damage.Q39813880
Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival.Q39906003
SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clockQ40118969
Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer.Q40134202
Glycogen synthase kinase-3beta positively regulates the proliferation of human ovarian cancer cellsQ40264789
The regulation of IGF-I receptor gene expression.Q40381637
Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cellsQ40444210
A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylationQ40795858
AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells.Q40824440
Src stimulates insulin-like growth factor I (IGF-I)-dependent cell proliferation by increasing IGF-I receptor number in human pancreatic carcinoma cells.Q41012238
The IGF-I receptor gene promoter is a molecular target for the Ewing's sarcoma-Wilms' tumor 1 fusion proteinQ41175804
Forkhead transcription factor FOXO3a protein activates nuclear factor κB through B-cell lymphoma/leukemia 10 (BCL10) protein and promotes tumor cell survival in serum deprivationQ42183550
Can a two-faced kinase be exploited for osteosarcoma?Q42387864
P433issue36
P407language of work or nameEnglishQ1860
P1104number of pages12
P304page(s)24759-24770
P577publication date2014-07-22
P1433published inJournal of Biological ChemistryQ867727
P1476titleGSK3 protein positively regulates type I insulin-like growth factor receptor through forkhead transcription factors FOXO1/3/4
P478volume289

Reverse relations

cites work (P2860)
Q41526032DAF-16/FOXO Transcription Factor in Aging and Longevity
Q28074586Epstein-Barr Virus: Diseases Linked to Infection and Transformation
Q47095382Function of insulin-like growth factor 1 receptor in cancer resistance to chemotherapy
Q90019609GSK-3β inhibition protects the rat heart from the lipopolysaccharide-induced inflammation injury via suppressing FOXO3A activity
Q90644165GSK3-β promotes calpain-1-mediated desmin filament depolymerization and myofibril loss in atrophy
Q33829976Inhibition of ERK1/2 Restores GSK3β Activity and Protein Synthesis Levels in a Model of Tuberous Sclerosis
Q92237212MAT2B expression correlates with poor prognosis in triple-negative breast cancer
Q97644577Modulated Expression of the Protein Kinase GSK3 in Motor and Dopaminergic Neurons Increases Female Lifespan in Drosophila melanogaster
Q91639718Protein synthesis signaling in skeletal muscle is refractory to whey protein ingestion during a severe energy deficit evoked by prolonged exercise and caloric restriction
Q26799843Redox regulation of FoxO transcription factors
Q50057271Regulation of FOXO Factors in Mammalian Cells.
Q54114703Requirement of GSK-3 for PUMA induction upon loss of pro-survival PI3K signaling.
Q38800014Shikonin Derivative DMAKO-05 Inhibits Akt Signal Activation and Melanoma Proliferation.
Q58745106Tanshinone IIA Attenuates Insulin Like Growth Factor 1 -Induced Cell Proliferation in PC12 Cells through the PI3K/Akt and MEK/ERK Pathways
Q43950297The Indirubin Derivative 6-Bromoindirubin-3'-Oxime Activates Proteostatic Modules, Reprograms Cellular Bioenergetic Pathways, and Exerts Antiaging Effects

Search more.