scholarly article | Q13442814 |
P50 | author | Paolo Botta | Q79611880 |
María Soledad Esposito | Q39698421 | ||
P2093 | author name string | Matthias Müller | |
Tewis Bouwmeester | |||
Sascha Fuchs | |||
Andreas Lüthi | |||
Silvia Arber | |||
Claus Rieker | |||
Francesco Paolo Di Giorgio | |||
Dorothee Bleckmann | |||
Herman van der Putten | |||
Ivan Galimberti | |||
Mario Bernhard | |||
Eline Pecho-Vrieseling | |||
Chris Goldstein | |||
P2860 | cites work | Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model | Q24631645 |
Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates | Q24657543 | ||
Synaptic vesicle exocytosis | Q26269869 | ||
How to make a hippocampal dentate gyrus granule neuron | Q26852799 | ||
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. | Q27860836 | ||
Embryonic stem cell lines derived from human blastocysts | Q27861010 | ||
Staging of brain pathology related to sporadic Parkinson's disease | Q28131702 | ||
SIRT2 ablation has no effect on tubulin acetylation in brain, cholesterol biosynthesis or the progression of Huntington's disease phenotypes in vivo | Q28482270 | ||
Trans-synaptic spread of tau pathology in vivo | Q28732288 | ||
A modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promoters | Q28732825 | ||
Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis | Q39809906 | ||
Single-step detection of mutant huntingtin in animal and human tissues: a bioassay for Huntington's disease | Q39815137 | ||
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies | Q41760966 | ||
Brainstem nucleus MdV mediates skilled forelimb motor tasks | Q42239582 | ||
Motor-circuit communication matrix from spinal cord to brainstem neurons revealed by developmental origin | Q42239737 | ||
Axonal and subcellular labelling using modified rabies viral vectors | Q42276697 | ||
Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice | Q42513638 | ||
New anti-huntingtin monoclonal antibodies: implications for huntingtin conformation and its binding proteins | Q42664318 | ||
Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease. | Q44306949 | ||
A disinhibitory microcircuit for associative fear learning in the auditory cortex. | Q44450801 | ||
Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release | Q44545687 | ||
Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes | Q45080144 | ||
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. | Q45296827 | ||
Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology. | Q45297497 | ||
Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice | Q45298466 | ||
TR-FRET-based duplex immunoassay reveals an inverse correlation of soluble and aggregated mutant huntingtin in huntington's disease | Q45306486 | ||
Staining protocol for organotypic hippocampal slice cultures | Q48218745 | ||
Beyond the prion principle | Q57083618 | ||
A Network Diffusion Model of Disease Progression in Dementia | Q29543923 | ||
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice | Q29615357 | ||
Propagation of tau pathology in a model of early Alzheimer's disease | Q29620203 | ||
Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice | Q29620597 | ||
Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice | Q30437914 | ||
Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice. | Q30512860 | ||
Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease | Q33726473 | ||
Huntington disease models and human neuropathology: similarities and differences | Q33760994 | ||
Huntington's disease: from molecular pathogenesis to clinical treatment | Q33773061 | ||
Evaluation of the therapeutic usefulness of botulinum neurotoxin B, C1, E, and F compared with the long lasting type A. Basis for distinct durations of inhibition of exocytosis in central neurons | Q34154552 | ||
Dysfunctional behavioral modulation of corticostriatal communication in the R6/2 mouse model of Huntington's disease | Q34442696 | ||
Atg4b-dependent autophagic flux alleviates Huntington's disease progression | Q34827331 | ||
Prions hijack tunnelling nanotubes for intercellular spread | Q34938949 | ||
Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death | Q35484581 | ||
Identification of the major steps in botulinum toxin action | Q35639122 | ||
DARPP-32: an integrator of neurotransmission | Q35639141 | ||
Predicting regional neurodegeneration from the healthy brain functional connectome | Q35991719 | ||
Botulinum neurotoxin A blocks synaptic vesicle exocytosis but not endocytosis at the nerve terminal | Q36313397 | ||
Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease | Q36598263 | ||
Huntington's disease: progress and potential in the field | Q37016096 | ||
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice | Q37072467 | ||
Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration | Q37268805 | ||
Protein aggregates in Huntington's disease. | Q37540988 | ||
Neuronal activity regulates extracellular tau in vivo | Q37630201 | ||
The transcellular spread of cytosolic amyloids, prions, and prionoids | Q37671889 | ||
Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function. | Q37930190 | ||
Huntington's disease and the striatal medium spiny neuron: cell-autonomous and non-cell-autonomous mechanisms of disease | Q37996350 | ||
Molecular logic of neocortical projection neuron specification, development and diversity | Q38150734 | ||
Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases | Q38185934 | ||
Physiological release of endogenous tau is stimulated by neuronal activity. | Q39560268 | ||
P2507 | corrigendum / erratum | Author Correction: Transneuronal propagation of mutant huntingtin contributes to non-cell autonomous pathology in neurons | Q90295292 |
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1064-1072 | |
P577 | publication date | 2014-07-13 | |
P1433 | published in | Nature Neuroscience | Q1535359 |
P1476 | title | Transneuronal propagation of mutant huntingtin contributes to non-cell autonomous pathology in neurons | |
P478 | volume | 17 |
Q51744369 | A novel ex vivo Huntington's disease model for studying GABAergic neurons and cell grafts by laser microdissection. |
Q30805841 | Affinity of Tau antibodies for solubilized pathological Tau species but not their immunogen or insoluble Tau aggregates predicts in vivo and ex vivo efficacy. |
Q46240783 | Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies. |
Q36768015 | Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes. |
Q63739888 | Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration |
Q36680329 | Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1 |
Q38860098 | Binding, internalization and fate of Huntingtin Exon1 fibrillar assemblies in mitotic and nonmitotic neuroblastoma cells |
Q37510411 | CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations |
Q47432409 | CSF in acute and chronic infectious diseases |
Q47118911 | Cell-to-cell Transmission of Polyglutamine Aggregates in C. elegans |
Q88673114 | Cellular mechanisms responsible for cell-to-cell spreading of prions |
Q26799722 | Developing stem cell therapies for juvenile and adult-onset Huntington's disease |
Q38766640 | DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins. |
Q47178205 | Dopamine and Acetylcholine, a Circuit Point of View in Parkinson's Disease |
Q47284348 | Editorial: Pathogenic templating proteins in Neurodegenerative Disease. |
Q35596571 | Engineered antibody therapies coming of age for aging brains |
Q39906624 | Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons |
Q38726920 | Exosomes and Homeostatic Synaptic Plasticity Are Linked to Each other and to Huntington's, Parkinson's, and Other Neurodegenerative Diseases by Database-Enabled Analyses of Comprehensively Curated Datasets |
Q96123053 | GLAST-CreERT2 mediated deletion of GDNF increases brain damage and exacerbates long-term stroke outcomes after focal ischemic stroke in mouse model |
Q104064832 | Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells |
Q40889402 | High-Throughput Screening Using iPSC-Derived Neuronal Progenitors to Identify Compounds Counteracting Epigenetic Gene Silencing in Fragile X Syndrome. |
Q49174268 | Hopping from One Cell to Another: Huntington's Disease Propagates |
Q27322062 | Human-to-mouse prion-like propagation of mutant huntingtin protein |
Q48871040 | Hunting cellular mechanisms underlying the spreading of misfolded protein pathology in the brain |
Q56083219 | Huntington disease |
Q98471370 | Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities |
Q39035495 | Huntington's Disease: Mechanisms of Pathogenesis and Therapeutic Strategies |
Q27318766 | Huntington's disease cerebrospinal fluid seeds aggregation of mutant huntingtin |
Q37652595 | Induced Pluripotent Stem Cells in Huntington's Disease: Disease Modeling and the Potential for Cell-Based Therapy |
Q47651159 | Induced neural stem cells as a means of treatment in Huntington's disease. |
Q64268462 | Molecular mechanisms of heterogeneous oligomerization of huntingtin proteins |
Q52631446 | Monitoring Cell-to-cell Transmission of Prion-like Protein Aggregates in Drosophila Melanogaster. |
Q45304134 | Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes |
Q38618002 | Mutant huntingtin is secreted via a late endosomal/lysosomal unconventional secretory pathway |
Q64944850 | N-terminal Huntingtin (Htt) phosphorylation is a molecular switch regulating Htt aggregation, helical conformation, internalization, and nuclear targeting. |
Q92678130 | Network spread determines severity of degeneration and disconnection in Huntington's disease |
Q45300817 | Neurodegenerative disease: propagating pathology |
Q27011744 | Neurodegenerative diseases: expanding the prion concept |
Q95940310 | Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses |
Q98735747 | Phase Transition of Huntingtin: Factors and Pathological Relevance |
Q38788190 | Potential Transfer of Polyglutamine and CAG-Repeat RNA in Extracellular Vesicles in Huntington's Disease: Background and Evaluation in Cell Culture |
Q45305113 | Presence of tau pathology within foetal neural allografts in patients with Huntington's and Parkinson's disease |
Q38544624 | Primary cilia and autophagic dysfunction in Huntington's disease |
Q39092630 | Prion-Like Characteristics of Polyglutamine-Containing Proteins |
Q38922025 | Prion-like propagation as a pathogenic principle in frontotemporal dementia. |
Q39167900 | Prion-like proteins and their computational identification in proteomes. |
Q35889023 | Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain |
Q58720864 | Rapid dissemination of alpha-synuclein seeds through neural circuits in an in-vivo prion-like seeding experiment |
Q58095410 | Regional subcortical shape analysis in premanifest Huntington's disease |
Q28073306 | Regulation of cell-non-autonomous proteostasis in metazoans |
Q91929130 | Rhes travels from cell to cell and transports Huntington disease protein via TNT-like protrusion |
Q28082714 | Role of Different Alpha-Synuclein Strains in Synucleinopathies, Similarities with other Neurodegenerative Diseases |
Q40995496 | Secretory carrier membrane protein 5 is an autophagy inhibitor that promotes the secretion of α-synuclein via exosome |
Q92187419 | Selective Neuronal Death in Neurodegenerative Diseases: The Ongoing Mystery |
Q36206024 | Selective vulnerability of Rich Club brain regions is an organizational principle of structural connectivity loss in Huntington's disease |
Q45300759 | Something wicked this way comes: huntingtin |
Q47102449 | The Evidence for the Spread and Seeding Capacities of the Mutant Huntingtin Protein in in Vitro Systems and Their Therapeutic Implications |
Q41334055 | The Generation of Mouse and Human Huntington Disease iPS Cells Suitable for In vitro Studies on Huntingtin Function |
Q41447335 | The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases. |
Q58780088 | The Tiny for the Biggest Answers in Huntington's Disease |
Q34467650 | The biology of proteostasis in aging and disease |
Q26828403 | The choreography of neuroinflammation in Huntington's disease |
Q39445835 | The spread of prion-like proteins by lysosomes and tunneling nanotubes: Implications for neurodegenerative diseases. |
Q36120432 | Transcellular spreading of huntingtin aggregates in the Drosophila brain |
Q55515366 | Unconventional Secretion and Intercellular Transfer of Mutant Huntingtin. |
Q30835807 | Whole-brain 3D mapping of human neural transplant innervation. |
Q55259534 | hPSC-Derived Striatal Cells Generated Using a Scalable 3D Hydrogel Promote Recovery in a Huntington Disease Mouse Model. |
Search more.