Autoinducer 2 Signaling via the Phosphotransferase FruA Drives Galactose Utilization by Streptococcus pneumoniae, Resulting in Hypervirulence

scientific article published on 24 January 2017

Autoinducer 2 Signaling via the Phosphotransferase FruA Drives Galactose Utilization by Streptococcus pneumoniae, Resulting in Hypervirulence is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MBIO.02269-16
P932PMC publication ID5263250
P698PubMed publication ID28119473

P50authorMarco R. OggioniQ42137324
Christopher A McDevittQ56812938
Claudia TrappettiQ63727536
P2093author name stringHui Wang
Adrienne W Paton
James C Paton
Lauren J McAllister
Austen Chen
P2860cites workDifferential expression analysis for sequence count dataQ21184103
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Host glycan sugar-specific pathways in Streptococcus pneumoniae: galactose as a key sugar in colonisation and infection [corrected]Q27311184
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Does efficiency sensing unify diffusion and quorum sensing?Q33274074
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Characterization of novel beta-galactosidase activity that contributes to glycoprotein degradation and virulence in Streptococcus pneumoniaeQ33557890
Extracellular matrix formation enhances the ability of Streptococcus pneumoniae to cause invasive diseaseQ33911080
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The languages of bacteria.Q34284947
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Salmonella typhimurium recognizes a chemically distinct form of the bacterial quorum-sensing signal AI-2.Q34345959
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Environmental and nutritional factors that affect growth and metabolism of the pneumococcal serotype 2 strain D39 and its nonencapsulated derivative strain R6.Q34625859
Attachment of capsular polysaccharide to the cell wall of Streptococcus pneumoniae type 2 is required for invasive diseaseQ34694425
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The LuxS-dependent quorum-sensing system regulates early biofilm formation by Streptococcus pneumoniae strain D39.Q35272989
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LuxS mediates iron-dependent biofilm formation, competence, and fratricide in Streptococcus pneumoniae.Q35671661
Quorum sensing in Escherichia coli is signaled by AI-2/LsrR: effects on small RNA and biofilm architecture.Q35949964
Making 'sense' of metabolism: autoinducer-2, LuxS and pathogenic bacteria.Q36111883
Identification of genes that contribute to the pathogenesis of invasive pneumococcal disease by in vivo transcriptomic analysisQ36163091
Pneumococcal interactions with epithelial cells are crucial for optimal biofilm formation and colonization in vitro and in vivo.Q36211192
How phosphotransferase system-related protein phosphorylation regulates carbohydrate metabolism in bacteriaQ36678721
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Pneumococcal modification of host sugars: a major contributor to colonization of the human airway?Q37717781
Quorum sensing and bacterial social interactions in biofilmsQ38021990
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LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genesQ40763983
THE PROTECTIVE ACTION OF A SPECIFIC ENZYME AGAINST TYPE III PNEUMOCOCCUS INFECTION IN MICE.Q42139101
Phosphoproteomic analysis reveals the multiple roles of phosphorylation in pathogenic bacterium Streptococcus pneumoniaeQ43247100
Lsr-mediated transport and processing of AI-2 in Salmonella typhimuriumQ44658473
Factors determining the appearance of glucose in upper and lower respiratory tract secretionsQ44675291
A study of the genetic material determining an enzyme activity in PneumococcusQ44711463
Deglycosylation of human glycoconjugates by the sequential activities of exoglycosidases expressed by Streptococcus pneumoniaeQ46899381
LuxS impacts on LytA-dependent autolysis and on competence in Streptococcus pneumoniaeQ46911395
To have neighbour's fare: extending the molecular toolbox for Streptococcus pneumoniaeQ46911402
Method for introducing specific and unmarked mutations into the chromosome of Streptococcus pneumoniae.Q51720762
Phosphoenolpyruvate phosphotransferase system regulates detection and processing of the quorum sensing signal autoinducer-2.Q54341225
Differential expression of key pneumococcal virulence genes in vivoQ58888617
AI-2 quorum sensing affects antibiotic susceptibility in Streptococcus anginosusQ60587199
Pneumococcal conjugate vaccine for childhood immunization--WHO position paperQ80021166
P4510describes a project that usesDESeq2Q113018293
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectStreptococcus pneumoniaeQ221179
P577publication date2017-01-24
P1433published inmBioQ15817061
P1476titleAutoinducer 2 Signaling via the Phosphotransferase FruA Drives Galactose Utilization by Streptococcus pneumoniae, Resulting in Hypervirulence
P478volume8

Reverse relations

cites work (P2860)
Q61448431Capacity To Utilize Raffinose Dictates Pneumococcal Disease Phenotype
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Q64236686Interference With Quorum-Sensing Signal Biosynthesis as a Promising Therapeutic Strategy Against Multidrug-Resistant Pathogens
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Q90403311TprA/PhrA Quorum Sensing System Has a Major Effect on Pneumococcal Survival in Respiratory Tract and Blood, and Its Activity Is Controlled by CcpA and GlnR

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