Kaempferol suppresses bladder cancer tumor growth by inhibiting cell proliferation and inducing apoptosis

scientific article published on 2 April 2014

Kaempferol suppresses bladder cancer tumor growth by inhibiting cell proliferation and inducing apoptosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/MC.22154
P698PubMed publication ID24700700

P2093author name stringLei Li
Feng Li
Jin Zeng
Luke S Chang
Qiang Dang
Dalin He
Guodong Zhu
Defeng Xu
Xinyang Wang
Wenbin Song
Yanmin Ma
P2860cites workGlobal cancer statisticsQ22241238
Molecular cloning and expression of human hepatocyte growth factorQ24305558
Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell deathQ24673503
Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activationQ28131755
Flavonols and pancreatic cancer risk: the multiethnic cohort studyQ28240121
A review on the dietary flavonoid kaempferolQ28307823
High intake of specific carotenoids and flavonoids does not reduce the risk of bladder cancerQ33849371
Kaempferol enhances cisplatin's effect on ovarian cancer cells through promoting apoptosis caused by down regulation of cMycQ33914646
Dysregulation of Met receptor tyrosine kinase activity in invasive tumorsQ34584046
Upregulation of TRAG3 gene in urothelial carcinoma of the bladder.Q34861259
Immunotherapy for superficial bladder cancerQ35964134
HGF/SF-Met signaling in tumor progressionQ36027374
Diet and cancer prevention: where we are, where we are goingQ36809102
Executioner caspase-3 and caspase-7 are functionally distinct proteasesQ36861736
Ganglioside GM2/GM3 complex affixed on silica nanospheres strongly inhibits cell motility through CD82/cMet-mediated pathwayQ36882981
Flavonoid intake and ovarian cancer risk in a population-based case-control studyQ37244256
Kaempferol promotes apoptosis in human bladder cancer cells by inducing the tumor suppressor, PTEN.Q37375285
Kaempferol inhibits angiogenesis and VEGF expression through both HIF dependent and independent pathways in human ovarian cancer cellsQ37406640
Hepatocyte growth factor and its receptor signalling complex as targets in cancer therapyQ37656383
Roles of HIF-1α in a novel optical orthotopic spontaneous metastatic bladder cancer animal modelQ39395549
Phenolic-Containing Organic Extracts of Mulberry (Morus alba L.) Leaves Inhibit HepG2 Hepatoma Cells Through G2/M Phase Arrest, Induction of Apoptosis, and Inhibition of Topoisomerase IIα ActivityQ39657652
Kaempferol induces apoptosis in two different cell lines via Akt inactivation, Bax and SIRT3 activation, and mitochondrial dysfunctionQ39892291
The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivinQ39918809
A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant K-rasQ39991720
Kaempferol induces apoptosis in glioblastoma cells through oxidative stressQ40079278
Kaempferol induces apoptosis in human lung non-small carcinoma cells accompanied by an induction of antioxidant enzymesQ40116972
A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenograftsQ40144642
Structure-activity relationships of flavonoid-induced cytotoxicity on human leukemia cellsQ40160244
Combined inhibitory effects of green tea polyphenols and selective cyclooxygenase-2 inhibitors on the growth of human prostate cancer cells both in vitro and in vivo.Q40164519
Differential signaling by alternative HGF isoforms through c-Met: activation of both MAP kinase and PI 3-kinase pathways is insufficient for mitogenesisQ40949581
Dietary flavonoid intake and lung cancer--a population-based case-control study.Q41277914
Hepatocyte growth factor/scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways.Q42508524
Kaempferol-induced growth inhibition and apoptosis in A549 lung cancer cells is mediated by activation of MEK-MAPK.Q44564572
Cytotoxicity of flavones and flavonols to a human esophageal squamous cell carcinoma cell line (KYSE-510) by induction of G2/M arrest and apoptosis.Q46034803
Flavonoids and the risk of renal cell carcinomaQ46786814
P433issue9
P921main subjectbladder cancerQ504775
P304page(s)831-840
P577publication date2014-04-02
P1433published inMolecular CarcinogenesisQ15724597
P1476titleKaempferol suppresses bladder cancer tumor growth by inhibiting cell proliferation and inducing apoptosis
P478volume54

Reverse relations

cites work (P2860)
Q55508457A Novel Flavonoid Composition Targets Androgen Receptor Signaling and Inhibits Prostate Cancer Growth in Preclinical Models.
Q39837951Biophysical exploration of protein-flavonol recognition: effects of molecular properties and conformational flexibility
Q39354574Dietary Intervention by Phytochemicals and Their Role in Modulating Coding and Non-Coding Genes in Cancer.
Q34305653Fibroblast and Epidermal Growth Factors Utilize Different Signaling Pathways to Induce Anchorage-independent Cell Transformation in JB6 Cl41 Mouse Skin Epidermal Cells
Q41836861Honey and Cancer: Current Status and Future Directions
Q39168097Implications of Resveratrol on Glucose Uptake and Metabolism.
Q51653613In Vivo Exposure of Kaempferol Is Driven by Phase II Metabolic Enzymes and Efflux Transporters.
Q60951707Inhibitory Effect of Synthetic Flavone Derivatives on Pan-Aurora Kinases: Induction of G2/M Cell-Cycle Arrest and Apoptosis in HCT116 Human Colon Cancer Cells
Q41481842KAEMPFEROL, A FLAVONOID COMPOUND FROM GYNURA MEDICA INDUCED APOPTOSIS AND GROWTH INHIBITION IN MCF-7 BREAST CANCER CELL.
Q57478840Kaempferol Attenuates ROS-Induced Hemolysis and the Molecular Mechanism of Its Induction of Apoptosis on Bladder Cancer
Q92222338Kaempferol Promotes Apoptosis While Inhibiting Cell Proliferation via Androgen-Dependent Pathway and Suppressing Vasculogenic Mimicry and Invasion in Prostate Cancer
Q64245020Kaempferol suppresses human gastric cancer SNU-216 cell proliferation, promotes cell autophagy, but has no influence on cell apoptosis
Q42825188Kaempferol suppresses lipid accumulation by inhibiting early adipogenesis in 3T3-L1 cells and zebrafish
Q91729237Kaempferol suppresses proliferation but increases apoptosis and autophagy by up-regulating microRNA-340 in human lung cancer cells
Q60240219Kaempferol – A dietary anticancer molecule with multiple mechanisms of action: Recent trends and advancements
Q93081698Kaempferol: A Key Emphasis to Its Anticancer Potential
Q94544661Mapping Pharmacological Network of Multi-Targeting Litchi Ingredients in Cancer Therapeutics
Q112284336Network Pharmacology-Based Study on the Active Component and Mechanism of the Anti-Non-Invasive and Invasive Bladder Urothelial Carcinoma Effects of Zhuling Jisheng Decoction
Q55241864Nimesulide inhibits proliferation and induces apoptosis of pancreatic cancer cells by enhancing expression of PTEN.
Q41680378Onset of the lymphocytic infiltration and hyperplasia preceding the proliferation in F1 mouse lungs from the N-ethyl-N-nitrosourea exposed mothers: Prevention during the lactation period by inositol hexaphosphate
Q57821021Phytochemical Characterization of L. Under Differential Dried-Conditions and Associated Nephrotoxicity Screening of Main Compound With Organ-on-a-Chip
Q58603612RNA sequencing and de novo assembly of Solanum trilobatum leaf transcriptome to identify putative transcripts for major metabolic pathways
Q36511338Sequencing, De novo Assembly, Functional Annotation and Analysis of Phyllanthus amarus Leaf Transcriptome Using the Illumina Platform
Q51309204The anti-obesity and anti-diabetic effects of kaempferol glycosides from unripe soybean leaves in high-fat-diet mice
Q38622919Therapeutic potential of flavonoids in inflammatory bowel disease: A comprehensive review

Search more.