Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy

scientific article published on 7 March 2014

Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/CDD.2014.31
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/cdd.2014.31
P932PMC publication ID4207480
P698PubMed publication ID24608791
P5875ResearchGate publication ID260645831

P2093author name stringY Han
G Lee
D Guo
M S Lesniak
A U Ahmed
M Dey
A L Tobias
B Auffinger
P2860cites workUnderstanding glioma stem cells: rationale, clinical relevance and therapeutic strategiesQ26995698
Glioma stem cells promote radioresistance by preferential activation of the DNA damage responseQ27860541
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastomaQ27860910
Identification of human brain tumour initiating cellsQ27860921
Identification of a cancer stem cell in human brain tumorsQ28131688
SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastomaQ28244307
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant gliomaQ28287898
Signatures of mutational processes in human cancerQ29547191
A restricted cell population propagates glioblastoma growth after chemotherapyQ29615605
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastomaQ29615607
Dose translation from animal to human studies revisitedQ29618049
Heterogeneity in cancer: cancer stem cells versus clonal evolutionQ29622839
Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisionsQ30429671
Phase I dose-escalation and pharmacokinetic study of temozolomide (SCH 52365) for refractory or relapsing malignanciesQ33330748
The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotypeQ33674720
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like stateQ34178901
Role of the Hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133+ pancreatic cancer stem-like cellsQ34253642
Acidic stress promotes a glioma stem cell phenotype.Q34985109
Chemoresistance of glioblastoma cancer stem cells--much more complex than expectedQ35521316
Asymmetry-defective oligodendrocyte progenitors are glioma precursorsQ35814886
BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expressionQ36347256
Cancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features.Q36763883
Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivoQ37096766
The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastomaQ37124552
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cellsQ37221453
Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectorsQ37447217
Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft modelQ37467299
Tumor-promoting functions of transforming growth factor-β in progression of cancer.Q37960077
Mismatch repair deficient human cells: spontaneous and MNNG-induced mutational spectra in the HPRT geneQ38311693
Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomideQ39593159
Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status.Q39648560
A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alphaQ39717521
Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenograftsQ39924899
Temozolomide preferentially depletes cancer stem cells in glioblastomaQ39960750
The Warburg effect version 2.0: metabolic reprogramming of cancer stem cellsQ41831013
Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/β-catenin pathwayQ41833207
AP-1 Gene Expression Levels May Be Correlated with Changes in Gene Expression of Some Stemness Factors in Colon CarcinomasQ41969007
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cellsQ42148487
Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patientsQ44918010
A new model for prediction of drug distribution in tumor and normal tissues: pharmacokinetics of temozolomide in glioma patientsQ46178285
Chemotherapy resistance of glioblastoma stem cellsQ46926270
Safety and feasibility of long-term temozolomide treatment in patients with high-grade glioma.Q48260300
Human brain glioma stem cells are more invasive than their differentiated progeny cells in vitro.Q48792526
Stem cell marker CD133 affects clinical outcome in glioma patients.Q53507481
Runx1 protects hematopoietic stem/progenitor cells from oncogenic insultQ81152616
P433issue7
P921main subjectglioblastomaQ282142
chemotherapyQ974135
P304page(s)1119-1131
P577publication date2014-03-07
P1433published inCell Death & DifferentiationQ2943974
P1476titleConversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy
P478volume21

Reverse relations

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