scholarly article | Q13442814 |
P356 | DOI | 10.1038/CDD.2014.31 |
P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/cdd.2014.31 |
P932 | PMC publication ID | 4207480 |
P698 | PubMed publication ID | 24608791 |
P5875 | ResearchGate publication ID | 260645831 |
P2093 | author name string | Y Han | |
G Lee | |||
D Guo | |||
M S Lesniak | |||
A U Ahmed | |||
M Dey | |||
A L Tobias | |||
B Auffinger | |||
P2860 | cites work | Understanding glioma stem cells: rationale, clinical relevance and therapeutic strategies | Q26995698 |
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response | Q27860541 | ||
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma | Q27860910 | ||
Identification of human brain tumour initiating cells | Q27860921 | ||
Identification of a cancer stem cell in human brain tumors | Q28131688 | ||
SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma | Q28244307 | ||
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma | Q28287898 | ||
Signatures of mutational processes in human cancer | Q29547191 | ||
A restricted cell population propagates glioblastoma growth after chemotherapy | Q29615605 | ||
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma | Q29615607 | ||
Dose translation from animal to human studies revisited | Q29618049 | ||
Heterogeneity in cancer: cancer stem cells versus clonal evolution | Q29622839 | ||
Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions | Q30429671 | ||
Phase I dose-escalation and pharmacokinetic study of temozolomide (SCH 52365) for refractory or relapsing malignancies | Q33330748 | ||
The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype | Q33674720 | ||
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state | Q34178901 | ||
Role of the Hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133+ pancreatic cancer stem-like cells | Q34253642 | ||
Acidic stress promotes a glioma stem cell phenotype. | Q34985109 | ||
Chemoresistance of glioblastoma cancer stem cells--much more complex than expected | Q35521316 | ||
Asymmetry-defective oligodendrocyte progenitors are glioma precursors | Q35814886 | ||
BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression | Q36347256 | ||
Cancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features. | Q36763883 | ||
Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivo | Q37096766 | ||
The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma | Q37124552 | ||
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells | Q37221453 | ||
Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors | Q37447217 | ||
Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model | Q37467299 | ||
Tumor-promoting functions of transforming growth factor-β in progression of cancer. | Q37960077 | ||
Mismatch repair deficient human cells: spontaneous and MNNG-induced mutational spectra in the HPRT gene | Q38311693 | ||
Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide | Q39593159 | ||
Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status. | Q39648560 | ||
A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha | Q39717521 | ||
Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts | Q39924899 | ||
Temozolomide preferentially depletes cancer stem cells in glioblastoma | Q39960750 | ||
The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells | Q41831013 | ||
Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/β-catenin pathway | Q41833207 | ||
AP-1 Gene Expression Levels May Be Correlated with Changes in Gene Expression of Some Stemness Factors in Colon Carcinomas | Q41969007 | ||
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells | Q42148487 | ||
Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients | Q44918010 | ||
A new model for prediction of drug distribution in tumor and normal tissues: pharmacokinetics of temozolomide in glioma patients | Q46178285 | ||
Chemotherapy resistance of glioblastoma stem cells | Q46926270 | ||
Safety and feasibility of long-term temozolomide treatment in patients with high-grade glioma. | Q48260300 | ||
Human brain glioma stem cells are more invasive than their differentiated progeny cells in vitro. | Q48792526 | ||
Stem cell marker CD133 affects clinical outcome in glioma patients. | Q53507481 | ||
Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult | Q81152616 | ||
P433 | issue | 7 | |
P921 | main subject | glioblastoma | Q282142 |
chemotherapy | Q974135 | ||
P304 | page(s) | 1119-1131 | |
P577 | publication date | 2014-03-07 | |
P1433 | published in | Cell Death & Differentiation | Q2943974 |
P1476 | title | Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy | |
P478 | volume | 21 |
Q37697462 | A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma |
Q33597842 | Accumulation of low-dose BIX01294 promotes metastatic potential of U251 glioblastoma cells |
Q90442508 | Acquisition of temozolomide resistance by the rat C6 glioma cell line increases cell migration and side population phenotype |
Q90750347 | Actinomycin D Downregulates Sox2 and Improves Survival in Preclinical Models of Recurrent Glioblastoma |
Q90446030 | All-trans retinoic acid therapy induces asymmetric division of glioma stem cells from the U87MG cell line |
Q36545726 | Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth |
Q26796793 | Autophagy in Cancer Stem Cells: A Potential Link Between Chemoresistance, Recurrence, and Metastasis |
Q92637402 | B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma |
Q28066409 | Bidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneity |
Q34518394 | CD66+ cells in cervical precancers are partially differentiated progenitors with neoplastic traits |
Q52571378 | Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment. |
Q37441234 | Cancer Stem Cells: Cellular Plasticity, Niche, and its Clinical Relevance |
Q35829972 | Cancer stem cells in glioblastoma |
Q37598500 | Cancer stem-like cells can be induced through dedifferentiation under hypoxic conditions in glioma, hepatoma and lung cancer |
Q38883388 | Cannabidiol stimulates Aml-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2-dependent manner |
Q90751934 | Capture at the single cell level of metabolic modules distinguishing aggressive and indolent glioblastoma cells |
Q35828103 | Cellular plasticity regulated cancer stem cell niche: a possible new mechanism of chemoresistance |
Q47964508 | Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness. |
Q63513061 | Characterization of Ablation Thresholds for 3D-Cultured Patient-Derived Glioma Stem Cells in Response to High-Frequency Irreversible Electroporation |
Q38431462 | Chemoresistance and chemotherapy targeting stem-like cells in malignant glioma. |
Q39354541 | Chemotherapeutic Drugs: DNA Damage and Repair in Glioblastoma |
Q91972239 | Chemotherapeutic Stress Induces Transdifferentiation of Glioblastoma Cells to Endothelial Cells and Promotes Vascular Mimicry |
Q37327524 | Cisplatin induces stemness in ovarian cancer |
Q38724559 | Connective tissue growth factor promotes temozolomide resistance in glioblastoma through TGF-β1-dependent activation of Smad/ERK signaling |
Q38739262 | Dedifferentiation of Glioma Cells to Glioma Stem-like Cells By Therapeutic Stress-induced HIF Signaling in the Recurrent GBM Model |
Q34859989 | Deregulated proliferation and differentiation in brain tumors. |
Q35788935 | Development of a Sox2 reporter system modeling cellular heterogeneity in glioma |
Q38777339 | Downregulation of HIF-1a sensitizes U251 glioma cells to the temozolomide (TMZ) treatment |
Q90641550 | Drug resistance in papillary RCC: from putative mechanisms to clinical practicalities |
Q90168279 | ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation |
Q55434339 | Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p. |
Q38843112 | Endothelial cells induce cancer stem cell features in differentiated glioblastoma cells via bFGF. |
Q96128431 | Epigenetics and metabolism at the crossroads of stress-induced plasticity, stemness and therapeutic resistance in cancer |
Q89893288 | Glioblastoma Stem Cells: Driving Resilience through Chaos |
Q64056689 | Glioblastoma Stem- Cells, Metabolic Strategy to Kill a Challenging Target |
Q35794896 | Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs. |
Q47385937 | HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy. |
Q41367064 | HIF1α regulates glioma chemosensitivity through the transformation between differentiation and dedifferentiation in various oxygen levels |
Q33709584 | HIF1α regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia |
Q55030657 | Heterogenic expression of stem cell markers in patient-derived glioblastoma spheroid cultures exposed to long-term hypoxia. |
Q42099075 | High expression of miR-9 in CD133(+) glioblastoma cells in chemoresistance to temozolomide |
Q89112546 | Identification of Compounds That Decrease Glioblastoma Growth and Glucose Uptake in Vitro |
Q55424304 | Immune Curbing of Cancer Stem Cells by CTLs Directed to NANOG. |
Q55708895 | Impact of Environmental Pollutant Cadmium on the Establishment of a Cancer Stem Cell Population in Breast and Hepatic Cancer. |
Q44411444 | Interest of integrins targeting in glioblastoma according to tumor heterogeneity and cancer stem cell paradigm: an update |
Q64101467 | Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma |
Q37274612 | Intranasal Oncolytic Virotherapy with CXCR4-Enhanced Stem Cells Extends Survival in Mouse Model of Glioma |
Q34662363 | Ionizing radiations sustain glioblastoma cell dedifferentiation to a stem-like phenotype through survivin: possible involvement in radioresistance |
Q92738186 | Irradiation enhances the therapeutic effect of the oncolytic adenovirus XVir-N-31 in brain tumor initiating cells |
Q48181924 | MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance. |
Q64389003 | Mebendazole Potentiates Radiation Therapy in Triple-Negative Breast Cancer |
Q64906270 | Metabolic traits of cancer stem cells. |
Q92269858 | Modulation of biliary cancer chemo-resistance through microRNA-mediated rewiring of the expansion of CD133+ cells |
Q59795056 | Molecular Mechanisms Governing the Stem Cell's Fate in Brain Cancer: Factors of Stemness and Quiescence |
Q52091959 | NF-κB Signalling in Glioblastoma. |
Q47598471 | NFκB Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH+ Cancer Stem-like Cells. |
Q99238265 | Nestin Expression Affects Resistance to Chemotherapy and Clinical Outcome in Small Cell Lung Cancer |
Q64251635 | N⁶-Methyladenosine Landscape of Glioma Stem-Like Cells: METTL3 Is Essential for the Expression of Actively Transcribed Genes and Sustenance of the Oncogenic Signaling |
Q26745942 | Oncolytic viruses as immunotherapy: progress and remaining challenges |
Q29248396 | Overcoming therapeutic resistance in glioblastoma: the way forward |
Q34457728 | Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth |
Q53078069 | Phenotypic Plasticity, Bet-Hedging, and Androgen Independence in Prostate Cancer: Role of Non-Genetic Heterogeneity. |
Q37688468 | Preclinical investigation of ibrutinib, a Bruton's kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes. |
Q35376154 | Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation. |
Q58572053 | R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells |
Q94495177 | Radiation-induced extracellular vesicle (EV) release of miR-603 promotes IGF1-mediated stem cell state in glioblastomas |
Q26752579 | Radioresistance of Brain Tumors |
Q47849042 | Radiotherapy and Glioma Stem Cells: Searching for Chinks in Cellular Armor |
Q49883157 | Recurrent Glioblastomas Exhibit Higher Expression of Biomarkers with Stem-like Properties. |
Q64389337 | Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells |
Q37708637 | Resistance to Cell Death and Its Modulation in Cancer Stem Cells |
Q35808894 | Resveratrol Inhibits the Invasion of Glioblastoma-Initiating Cells via Down-Regulation of the PI3K/Akt/NF-κB Signaling Pathway |
Q38703641 | Reversing glioma malignancy: a new look at the role of antidepressant drugs as adjuvant therapy for glioblastoma multiforme |
Q39190733 | Revisiting CDK Inhibitors for Treatment of Glioblastoma Multiforme |
Q38373829 | SOX2 immunity and tissue resident memory in children and young adults with glioma |
Q38689740 | Significance of low mTORC1 activity in defining the characteristics of brain tumor stem cells |
Q64110008 | Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment |
Q37423898 | Suberoylanilide hydroxamic acid represses glioma stem-like cells. |
Q64065428 | Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells |
Q37615744 | Targeting CD133 improves chemotherapeutic efficacy of recurrent pediatric pilocytic astrocytoma following prolonged chemotherapy |
Q64903427 | Targeting Hyaluronan Interactions for Glioblastoma Stem Cell Therapy. |
Q48866117 | Targeting therapy-resistant cancer stem cells by hyperthermia. |
Q36875981 | Temozolomide promotes genomic and phenotypic changes in glioblastoma cells. |
Q47850878 | Temozolomide-induced increase of tumorigenicity can be diminished by targeting of mitochondria in in vitro models of patient individual glioblastoma. |
Q59809879 | The Dilemma of Cure and Damage in Oligodendroglioma: Ways to Tip the Balance Away from the Damage |
Q102152114 | The HIF1α/HIF2α-miR210-3p network regulates glioblastoma cell proliferation, dedifferentiation and chemoresistance through EGF under hypoxic conditions |
Q89088558 | The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance |
Q36498067 | The emerging roles of Oct4 in tumor-initiating cells |
Q64101370 | The landscape of the mesenchymal signature in brain tumours |
Q36795940 | The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence |
Q38770247 | The role of octamer binding transcription factors in glioblastoma multiforme |
Q34364774 | The tumor suppressor prostate apoptosis response-4 (Par-4) is regulated by mutant IDH1 and kills glioma stem cells |
Q38682559 | Therapeutic dormancy to delay postsurgical glioma recurrence: the past, present and promise of focal hypothermia. |
Q100530748 | Transitional dynamics of cancer stem cells in invasion and metastasis |
Q91698193 | Tumor propagating cells: drivers of tumor plasticity, heterogeneity, and recurrence |
Q37687644 | Tumor-initiating cell frequency is relevant for glioblastoma aggressiveness |
Q36048547 | UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response. |
Q35657822 | Unlocking the promise of oncolytic virotherapy in glioma: combination with chemotherapy to enhance efficacy |
Q55383998 | WNK1 kinase and its partners Akt, SGK1 and NBC-family Na+/HCO3- cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling. |
Q27023599 | Wound healing and cancer stem cells: inflammation as a driver of treatment resistance in breast cancer |
Q59358702 | [Immunotherapy - The New Era of Oncology] |
Q38824458 | miRNA-182 and the regulation of the glioblastoma phenotype - toward miRNA-based precision therapeutics |
Q57498203 | p53 and Cell Fate: Sensitizing Head and Neck Cancer Stem Cells to Chemotherapy |
Q41842526 | p73 promotes glioblastoma cell invasion by directly activating POSTN (periostin) expression |
Q34924186 | β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer |
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