Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss

scientific article published on 14 June 2013

Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00401-013-1141-6
P698PubMed publication ID23764841

P2093author name stringV Peter Collins
Yoshitaka Narita
Akihiko Yoshida
Makoto Ohno
Koichi Ichimura
Kensuke Tateishi
Nobutaka Kawahara
Shintaro Fukushima
Soichiro Shibui
Yuko Matsushita
Hideyuki Arita
Yasuji Miyakita
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Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypesQ35235698
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomasQ36236484
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TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewalQ36762656
Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas.Q37307623
Molecular pathogenesis of IDH mutations in gliomas.Q37991531
Novel anticancer therapeutics targeting telomeraseQ38030204
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Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancersQ40008535
Real-time quantitative polymerase chain reaction (qPCR) analysis with fluorescence resonance energy transfer (FRET) probes reveals differential expression of the four ERBB4 juxtamembrane region variants between medulloblastoma and pilocytic astrocytQ41814700
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomasQ42164790
Prediction of clinical course of diffusely infiltrating astrocytomas from telomerase expression and quantitated activity levelQ43806353
Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutationsQ44269667
CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomasQ45182713
Telomerase activity in human gliomas.Q48469177
MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 or IDH2 mutations.Q48824616
Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme.Q55472960
Mutational profile of the PTEN gene in primary human astrocytic tumors and cultivated xenografts.Q55476495
Telomerase activity in human brain tumours.Q55480252
P433issue2
P304page(s)267-276
P577publication date2013-06-14
P1433published inActa NeuropathologicaQ343168
P1476titleUpregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss
P478volume126

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