scholarly article | Q13442814 |
P50 | author | Ayaz Najafov | Q57325964 |
Hongbo Chen | Q62838254 | ||
P2093 | author name string | Junying Yuan | |
P2860 | cites work | Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule | Q24290576 |
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase | Q24302381 | ||
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis | Q24311815 | ||
TNF-alpha induces two distinct caspase-8 activation pathways | Q24313656 | ||
Structural basis of RIP1 inhibition by necrostatins | Q24323347 | ||
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha | Q24338113 | ||
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation | Q24338129 | ||
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells | Q24530100 | ||
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism | Q27685465 | ||
CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members | Q28201693 | ||
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB | Q28201706 | ||
The future of immune checkpoint therapy | Q28259862 | ||
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis | Q28594624 | ||
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death | Q28660873 | ||
Identification of RIP1 kinase as a specific cellular target of necrostatins | Q29616006 | ||
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury | Q29616008 | ||
RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells. | Q30679385 | ||
RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS. | Q33728908 | ||
Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis. | Q34216810 | ||
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis | Q34387272 | ||
Cross-priming | Q34503836 | ||
The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia | Q34527239 | ||
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway | Q34910947 | ||
Pronecrotic mixed lineage kinase domain-like protein expression is a prognostic biomarker in patients with early-stage resected pancreatic adenocarcinoma. | Q35320095 | ||
A decade of caspases | Q35591686 | ||
RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage | Q35679558 | ||
Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics | Q35686077 | ||
Activation of necroptosis in multiple sclerosis | Q35828763 | ||
A novel role for RIP1 kinase in mediating TNFα production | Q36071998 | ||
Necrostatin-1 reduces intestinal inflammation and colitis-associated tumorigenesis in mice | Q36309417 | ||
Mixed lineage kinase domain-like protein is a prognostic biomarker for cervical squamous cell cancer | Q36464781 | ||
Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models | Q36525166 | ||
Necroptosis in Niemann-Pick disease, type C1: a potential therapeutic target. | Q36774925 | ||
The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression. | Q36803448 | ||
The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors | Q36961482 | ||
Inflammation: a driving force speeds cancer metastasis | Q36986448 | ||
Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma | Q37061845 | ||
Low expression of mixed lineage kinase domain-like protein is associated with poor prognosis in ovarian cancer patients | Q37278775 | ||
IAP-targeted therapies for cancer | Q37302745 | ||
Blocking TCR restimulation induced necroptosis in adoptively transferred T cells improves tumor control. | Q37688373 | ||
Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death | Q38152946 | ||
Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis. | Q38754063 | ||
NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling. | Q38837455 | ||
Necroptosis is active in children with inflammatory bowel disease and contributes to heighten intestinal inflammation | Q39045044 | ||
RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells | Q39605503 | ||
Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice. | Q40416781 | ||
Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase | Q42725146 | ||
Clinical significance of down-regulated cylindromatosis gene in chronic lymphocytic leukemia. | Q46030980 | ||
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. | Q52614520 | ||
Receptor-interacting protein kinase 3 is a predictor of survival and plays a tumor suppressive role in colorectal cancer. | Q54270795 | ||
SnapShot: Necroptosis. | Q54337095 | ||
The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation | Q62819741 | ||
P433 | issue | 4 | |
P921 | main subject | necroptosis | Q3346925 |
P304 | page(s) | 294-301 | |
P577 | publication date | 2017-04-01 | |
P1433 | published in | Trends in cancer | Q27726777 |
P1476 | title | Necroptosis and Cancer | |
P478 | volume | 3 |
Q92602547 | Characterization of TNF-induced cell death in Drosophila reveals caspase- and JNK-dependent necrosis and its role in tumor suppression |
Q93155695 | Elimination of Osteosarcoma by Necroptosis with Graphene Oxide-Associated Anti-HER2 Antibodies |
Q90170173 | Medicinal Plants from Brazilian Cerrado: Antioxidant and Anticancer Potential and Protection against Chemotherapy Toxicity |
Q92544553 | Necroptosis, tumor necrosis and tumorigenesis |
Q90370565 | Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis |
Q64244093 | Synergistic Effects of Bortezomib-OV Therapy and Anti-Invasive Strategies in Glioblastoma: A Mathematical Model |
Q55386853 | The role of necroptosis in the treatment of diseases. |
Q40063923 | Thioredoxin-1 actively maintains the pseudokinase MLKL in a reduced state to suppress disulfide bond-dependent MLKL polymer formation and necroptosis. |
Q89983838 | Transcription factors in ferroptotic cell death |
Q94521018 | Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation |
Q92408464 | Understanding Apoptosis and Apoptotic Pathways Targeted Cancer Therapeutics |
Q92431578 | miR-425 deficiency promotes necroptosis and dopaminergic neurodegeneration in Parkinson's disease |
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