Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis

scientific article published on 20 July 2018

Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1186/S12967-018-1580-X
P932PMC publication ID6053767
P698PubMed publication ID30029665

P2093author name stringHao Wang
Ye Ma
Linlin Jing
Xuegang Sun
Yu Dai
Chunhui Chen
Yawei Liu
Qinrui Han
P2860cites workPlasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosisQ24311815
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphomaQ24322614
Release of chromatin protein HMGB1 by necrotic cells triggers inflammationQ28131815
Tumour invasion and metastasis initiated by microRNA-10b in breast cancerQ28131829
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosisQ28594624
Molecular mechanisms of necroptosis: an ordered cellular explosionQ29616004
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012Q29616161
Shikonin circumvents cancer drug resistance by induction of a necroptotic deathQ80358241
The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosisQ33641040
Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)Q33841579
RIP3 overexpression sensitizes human breast cancer cells to parthenolide in vitro via intracellular ROS accumulationQ33869714
Regulated necrosis: the expanding network of non-apoptotic cell death pathways.Q34039639
Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.Q34413744
Colorectal cancer statistics, 2017.Q34552373
Clonogenic assay of cells in vitro.Q34615431
Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastasesQ35709696
Liver-targeting Resibufogenin-loaded poly(lactic-co-glycolic acid)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles for liver cancer therapy.Q35921769
Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell deathQ36347249
Parthenolide and DMAPT exert cytotoxic effects on breast cancer stem-like cells by inducing oxidative stress, mitochondrial dysfunction and necrosisQ36866492
RIP kinases at the crossroads of cell death and survivalQ37562142
A human programmed death-ligand 1-expressing mouse tumor model for evaluating the therapeutic efficacy of anti-human PD-L1 antibodiesQ37644337
The role of the kinases RIP1 and RIP3 in TNF-induced necrosisQ37721675
Killing a cancer: what are the alternatives?Q38009194
IL-33 promotes growth and liver metastasis of colorectal cancer in mice by remodeling the tumor microenvironment and inducing angiogenesisQ38775054
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.Q38858686
Treatments for colorectal liver metastases: A new focus on a familiar concept.Q39033363
Necroptosis and Cancer.Q39268644
Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cellsQ39878879
Targeting the weak point of cancer by induction of necroptosisQ40109919
Multiple death pathways in TNF-treated fibroblasts: RIP3- and RIP1-dependent and independent routes.Q42939569
RIP kinases initiate programmed necrosisQ43292317
NF-kappaB inhibitor sesquiterpene parthenolide induces concurrently atypical apoptosis and cell necrosis: difficulties in identification of dead cells in such culturesQ44524735
Characterization of phase I metabolism of resibufogenin and evaluation of the metabolic effects on its antitumor activity and toxicityQ46634405
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectcolorectal cancerQ188874
necroptosisQ3346925
BufogeninQ27114274
P304page(s)201
P577publication date2018-07-20
P1433published inJournal of Translational MedicineQ15716664
P1476titleResibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis
P478volume16

Reverse relations

cites work (P2860)
Q98177427Advances in Molecular Mechanisms for Traditional Chinese Medicine Actions in Regulating Tumor Immune Responses
Q91260101Current translational potential and underlying molecular mechanisms of necroptosis
Q59811858Necroptosis in inflammatory bowel disease and other intestinal diseases
Q89477059Resibufogenin suppresses tumor growth and Warburg effect through regulating miR-143-3p/HK2 axis in breast cancer
Q64279044The role of necroptosis in cancer biology and therapy

Search more.