| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Vilma R Martins | Q45827808 |
| P2093 | author name string | Vilma Regina Martins | |
| Glaucia Noeli Maroso Hajj | |||
| Tiago Góss Santos | |||
| P2860 | cites work | Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression | Q24323029 |
| Guidelines for the nomenclature of the human heat shock proteins | Q24653946 | ||
| Phospholipse c inhibitor, u73122, stimulates release of hsp-70 stress protein from A431 human carcinoma cells | Q24804032 | ||
| Extracellular Release and Signaling by Heat Shock Protein 27: Role in Modifying Vascular Inflammation | Q26738276 | ||
| Heat Shock Protein-Peptide and HSP-Based Immunotherapies for the Treatment of Cancer | Q26747392 | ||
| Chemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosis | Q27004511 | ||
| Rab-mediated vesicle trafficking in cancer | Q28074747 | ||
| Hsp20 functions as a novel cardiokine in promoting angiogenesis via activation of VEGFR2 | Q28118019 | ||
| Acetylsalicylic acid-induced release of HSP70 from mast cells results in cell activation through TLR pathway | Q28194505 | ||
| Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness | Q28261997 | ||
| The regulatory mechanism of Hsp90alpha secretion and its function in tumor malignancy | Q28266708 | ||
| Extracellular Hsp90 mediates an NF-κB dependent inflammatory stromal program: implications for the prostate tumor microenvironment | Q28304032 | ||
| Exercise increases serum Hsp72 in humans | Q28345140 | ||
| Hsp60 is actively secreted by human tumor cells | Q28472915 | ||
| Efficient induction of antitumor T cell immunity by exosomes derived from heat-shocked lymphoma cells | Q28509321 | ||
| Immunocytochemical localization of heat-shock protein 60-related protein in beta-cell secretory granules and its altered distribution in non-obese diabetic mice | Q28587354 | ||
| How dying cells alert the immune system to danger | Q29615501 | ||
| HSP90 and the chaperoning of cancer | Q29617504 | ||
| Extracellular heat shock protein A9 is a novel interaction partner of podoplanin in oral squamous cell carcinoma cells | Q30032657 | ||
| Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. | Q30805170 | ||
| Fingerprinting the circulating repertoire of antibodies from cancer patients | Q30877509 | ||
| Proteomic analysis of exosomes secreted by human mesothelioma cells | Q31052352 | ||
| Heat-shock protein 27: a potential biomarker for hepatocellular carcinoma identified by serum proteome analysis | Q33225672 | ||
| Exosomal Hsp70 induces a pro-inflammatory response to foreign particles including mycobacteria | Q33559877 | ||
| Chaperokine function of recombinant Hsp72 produced in insect cells using a baculovirus expression system is retained | Q33581297 | ||
| Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells | Q33604925 | ||
| Secretion of extracellular hsp90alpha via exosomes increases cancer cell motility: a role for plasminogen activation | Q33606225 | ||
| Treatment of colon and lung cancer patients with ex vivo heat shock protein 70-peptide-activated, autologous natural killer cells: a clinical phase i trial. | Q44917998 | ||
| Circulating heat-shock protein 70 is associated with postoperative infection and organ dysfunction after liver resection | Q44932341 | ||
| Hsp70 release from peripheral blood mononuclear cells. | Q45098360 | ||
| Heat shock protein 70 is secreted from endothelial cells by a non-classical pathway involving exosomes. | Q45952975 | ||
| Serum levels of Hsp 72 measured early after trauma correlate with survival | Q46479365 | ||
| Combination of imatinib mesylate with autologous leukocyte-derived heat shock protein and chronic myelogenous leukemia | Q46549109 | ||
| HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway | Q46600841 | ||
| Extracellular HSP90: conquering the cell surface | Q46602835 | ||
| Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 Study Group. | Q46748085 | ||
| Cell surface expression of 70 kDa heat shock protein in human oral dysplasia and squamous cell carcinoma: correlation with clinicopathological features. | Q47772583 | ||
| The unconventional secretion of stress-inducible protein 1 by a heterogeneous population of extracellular vesicles | Q48102618 | ||
| Hsp110 and Grp170, members of the Hsp70 superfamily, bind to scavenger receptor-A and scavenger receptor expressed by endothelial cells-I. | Q50337569 | ||
| Heat induced release of Hsp70 from prostate carcinoma cells involves both active secretion and passive release from necrotic cells | Q40213339 | ||
| Release of heat shock protein 70 (Hsp70) and the effects of extracellular Hsp70 on matric metalloproteinase-9 expression in human monocytic U937 cells | Q40235671 | ||
| Scavenger receptor-A mediates gp96/GRP94 and calreticulin internalization by antigen-presenting cells | Q40240250 | ||
| Extracellular targeting of endoplasmic reticulum chaperone glucose-regulated protein 170 enhances tumor immunity to a poorly immunogenic melanoma | Q40254205 | ||
| The release of Hsp70 from A431 carcinoma cells is mediated by secretory-like granules | Q40296627 | ||
| Induction of heat shock proteins in B-cell exosomes. | Q40392853 | ||
| Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells | Q40408986 | ||
| Calcium signaling in dendritic cells by human or mycobacterial Hsp70 is caused by contamination and is not required for Hsp70-mediated enhancement of cross-presentation | Q40421548 | ||
| Hsp70 plasma membrane expression on primary tumor biopsy material and bone marrow of leukemic patients | Q40424812 | ||
| Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteins | Q40436107 | ||
| Regulation of heat shock protein 70 release in astrocytes: role of signaling kinases. | Q40441827 | ||
| Induction of cytokines by heat shock proteins and endotoxin in murine macrophages | Q40565202 | ||
| Induction of Hsp90 protein expression in malignant melanomas and melanoma metastases | Q40580807 | ||
| Heat shock protein 70 (Hsp70) membrane expression on head-and-neck cancer biopsy-a target for natural killer (NK) cells. | Q40628707 | ||
| Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophages | Q40657222 | ||
| Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release by murine macrophages | Q40693930 | ||
| Immunization of cancer patients with autologous cancer-derived heat shock protein gp96 preparations: a pilot study | Q40746131 | ||
| HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway | Q40751242 | ||
| Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. | Q40751982 | ||
| Heat shock protein 60 levels in tissue and circulating exosomes in human large bowel cancer before and after ablative surgery | Q40851766 | ||
| The identification of secreted heat shock 60 -like protein from rat glial cells and a human neuroblastoma cell line | Q41018497 | ||
| Heat shock protein 72 on tumor cells: a recognition structure for natural killer cells | Q41114467 | ||
| Is cancer dangerous to the immune system? | Q41258077 | ||
| Hsp-70 is closely associated with the transferrin receptor in exosomes from maturing reticulocytes | Q41334691 | ||
| PRNP/prion protein regulates the secretion of exosomes modulating CAV1/caveolin-1-suppressed autophagy. | Q41741598 | ||
| Unusual expression and localization of heat-shock proteins in human tumor cells | Q41886360 | ||
| Immunomodulators released during rotavirus infection of polarized caco-2 cells. | Q42163234 | ||
| Localization of mitochondrial 60-kD heat shock chaperonin protein (Hsp60) in pituitary growth hormone secretory granules and pancreatic zymogen granules | Q42483016 | ||
| Exogenous heat shock protein 70 binds macrophage lipid raft microdomain and stimulates phagocytosis, processing, and MHC-II presentation of antigens | Q42486053 | ||
| Endocytosis and cancer | Q42869980 | ||
| Extracellular heat shock protein-90alpha: linking hypoxia to skin cell motility and wound healing | Q42929540 | ||
| A novel heat-shock protein coinducer boosts stress protein Hsp70 to activate T cell regulation of inflammation in autoimmune arthritis | Q43174044 | ||
| In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance | Q43751823 | ||
| Circulating human heat shock protein 60 in the plasma of British civil servants: relationship to physiological and psychosocial stress | Q44053737 | ||
| HSP20, low-molecular-weight heat shock-related protein, acts extracellularly as a regulator of platelet functions: a novel defense mechanism | Q44205430 | ||
| The 78 kDa glucose-regulated protein (GRP78/BIP) is expressed on the cell membrane, is released into cell culture medium and is also present in human peripheral circulation | Q44271462 | ||
| Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release | Q44394452 | ||
| Stress-induced release of HSC70 from human tumors | Q44491005 | ||
| Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway | Q44539124 | ||
| αB Crystallin Is Apically Secreted within Exosomes by Polarized Human Retinal Pigment Epithelium and Provides Neuroprotection to Adjacent Cells | Q33719278 | ||
| Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells | Q33831321 | ||
| Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP. | Q33832578 | ||
| Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer | Q33905697 | ||
| Post-translational modifications of exosomal proteins | Q34041809 | ||
| HSP60 is transported through the secretory pathway of 3-MCA-induced fibrosarcoma tumour cells and undergoes N-glycosylation | Q34225839 | ||
| The odyssey of Hsp60 from tumor cells to other destinations includes plasma membrane-associated stages and Golgi and exosomal protein-trafficking modalities | Q34359373 | ||
| Cell surface Cdc37 participates in extracellular HSP90 mediated cancer cell invasion | Q34388870 | ||
| Hsp40 gene therapy exerts therapeutic effects on polyglutamine disease mice via a non-cell autonomous mechanism | Q34506269 | ||
| Phosphatidylinositol 3-Kinase dependent upregulation of the epidermal growth factor receptor upon Flotillin-1 depletion in breast cancer cells. | Q34530534 | ||
| AlphaB-crystallin is found in detergent-resistant membrane microdomains and is secreted via exosomes from human retinal pigment epithelial cells | Q34536802 | ||
| An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial | Q34593792 | ||
| Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis. | Q34923990 | ||
| MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. | Q35062693 | ||
| Identification of human heat shock protein 60 (Hsp60) and anti-Hsp60 antibodies in the peripheral circulation of normal individuals | Q35084981 | ||
| Critical role of extracellular heat shock cognate protein 70 in the myocardial inflammatory response and cardiac dysfunction after global ischemia-reperfusion. | Q35109063 | ||
| Hsp90 C-terminal inhibitors exhibit antimigratory activity by disrupting the Hsp90α/Aha1 complex in PC3-MM2 cells | Q35121121 | ||
| CD204 suppresses large heat shock protein-facilitated priming of tumor antigen gp100-specific T cells and chaperone vaccine activity against mouse melanoma | Q35204505 | ||
| Heat shock proteins as emerging therapeutic targets | Q35545091 | ||
| Alternative mechanism by which IFN-gamma enhances tumor recognition: active release of heat shock protein 72. | Q35568966 | ||
| Surface expression of Hsp25 and Hsp72 differentially regulates tumor growth and metastasis | Q35574405 | ||
| Heat shock proteins: biological functions and clinical application as personalized vaccines for human cancer. | Q35613124 | ||
| Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level | Q35616052 | ||
| Secretion of αB-Crystallin via exosomes: New clues to the function of human retinal pigment epithelium | Q35836182 | ||
| Molecular chaperoning by glucose-regulated protein 170 in the extracellular milieu promotes macrophage-mediated pathogen sensing and innate immunity. | Q35863823 | ||
| Anticancer drugs cause release of exosomes with heat shock proteins from human hepatocellular carcinoma cells that elicit effective natural killer cell antitumor responses in vitro | Q35939788 | ||
| Secreted Hsp90 is a novel regulator of the epithelial to mesenchymal transition (EMT) in prostate cancer. | Q36368188 | ||
| Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic Environment | Q36548865 | ||
| Extracellular heat shock protein 90: a role for a molecular chaperone in cell motility and cancer metastasis | Q36889343 | ||
| Mechanisms for Hsp70 secretion: crossing membranes without a leader | Q36963116 | ||
| Heat Shock Proteins Promote Cancer: It's a Protection Racket | Q37013952 | ||
| A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer | Q37014915 | ||
| Inhibition of the Expression of the Small Heat Shock Protein αB-Crystallin Inhibits Exosome Secretion in Human Retinal Pigment Epithelial Cells in Culture | Q37065831 | ||
| Extracellular HSP110 skews macrophage polarization in colorectal cancer | Q37222077 | ||
| Detection of heat shock protein 70 (Hsp70) and anti-Hsp70 antibodies in the serum of normal individuals. | Q50853838 | ||
| The Hsp60 peptide p277 enhances anti-CD3 mediated diabetes remission in non-obese diabetic mice. | Q51044617 | ||
| In vivo treatment of mice with heat shock protein, gp 96, improves survival of skin grafts with minor and major antigenic disparity. | Q51822372 | ||
| Serum heat shock protein 27 is increased in chronic pancreatitis and pancreatic carcinoma. | Q51824143 | ||
| Heat shock proteins are no DAMPs, rather 'DAMPERs'. | Q53680750 | ||
| Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. | Q53878711 | ||
| Extracellular HSP60 triggers tissue regeneration and wound healing by regulating inflammation and cell proliferation. | Q54941897 | ||
| A phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-α in metastatic melanoma patients | Q57570360 | ||
| Exercise induces hepatosplanchnic release of heat shock protein 72 in humans | Q59326285 | ||
| A stress-inducible 72-kDa heat-shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells | Q61893867 | ||
| Heat shock proteins induce pores in membranes | Q68170427 | ||
| Selective release from cultured mammalian cells of heat-shock (stress) proteins that resemble glia-axon transfer proteins | Q69948836 | ||
| Exogenous heat shock protein hsp70 activates potassium channels in U937 cells | Q71186112 | ||
| Anti-heat-shock protein 70 kDa antibodies in vascular patients | Q73301863 | ||
| Identification and purification from the plasma of Type 1 diabetic subjects of a proteolytically active Grp94Evidence that Grp94 is entirely responsible for plasma proteolytic activity | Q73576003 | ||
| HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine | Q73606601 | ||
| Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer | Q73910273 | ||
| ATP and ADP modulate a cation channel formed by Hsc70 in acidic phospholipid membranes | Q74014525 | ||
| Circulating heat shock protein 60 is associated with early cardiovascular disease | Q74188186 | ||
| Serological detection of heat shock protein hsp27 in normal and breast cancer patients | Q77347906 | ||
| Endotoxin-free heat-shock protein 70 fails to induce APC activation | Q78759447 | ||
| Mycobacterium tuberculosis heat-shock protein 70 impairs maturation of dendritic cells from bone marrow precursors, induces interleukin-10 production and inhibits T-cell proliferation in vitro | Q79902443 | ||
| Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis | Q80446919 | ||
| Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands | Q80591503 | ||
| In vivo delivery of heat shock protein 70 accelerates wound healing by up-regulating macrophage-mediated phagocytosis | Q83185520 | ||
| Identification of protein clusters predictive of response to chemotherapy in breast cancer patients | Q84532822 | ||
| Heat shock protein 27 is over-expressed in tumor tissues and increased in sera of patients with gastric adenocarcinoma | Q84979928 | ||
| Binding of heat shock protein 70 to extracellular phosphatidylserine promotes killing of normoxic and hypoxic tumor cells | Q37280769 | ||
| Endocytic regulation of Notch signaling | Q37318272 | ||
| Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury | Q37394895 | ||
| Secretion of stress protein grp170 promotes immune-mediated inhibition of murine prostate tumor | Q37464444 | ||
| Lipid interaction differentiates the constitutive and stress-induced heat shock proteins Hsc70 and Hsp70. | Q37490470 | ||
| Stress-induced extracellular Hsp72 is a functionally significant danger signal to the immune system | Q37490925 | ||
| Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: a phase II, single-arm trial | Q37492175 | ||
| p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment | Q37698274 | ||
| Phosphoinositide signalling in cancer: beyond PI3K and PTEN. | Q37736257 | ||
| The heat shock response: life on the verge of death | Q37802041 | ||
| A case of mistaken identity: HSPs are no DAMPs but DAMPERs. | Q37964551 | ||
| Heat shock proteins in cancer: targeting the 'chaperones'. | Q38008726 | ||
| Protein rescue from aggregates by powerful molecular chaperone machines | Q38141722 | ||
| The epichaperome is an integrated chaperome network that facilitates tumour survival | Q38739896 | ||
| Anticancer Inhibitors of Hsp90 Function: Beyond the Usual Suspects | Q38750417 | ||
| Hsp90 as a "Chaperone" of the Epigenome: Insights and Opportunities for Cancer Therapy | Q38750423 | ||
| Forced expression of heat-shock protein 70 increases the secretion of Hsp70 and provides protection against tumour growth | Q38806106 | ||
| Ubiquitination as a Mechanism To Transport Soluble Mycobacterial and Eukaryotic Proteins to Exosomes | Q38846056 | ||
| Heat shock proteins as "danger signals": eukaryotic Hsp60 enhances and accelerates antigen-specific IFN-gamma production in T cells | Q38920563 | ||
| Disruption of prion protein-HOP engagement impairs glioblastoma growth and cognitive decline and improves overall survival | Q38963334 | ||
| Homeostasis-altering molecular processes as mechanisms of inflammasome activation | Q38978061 | ||
| Transforming growth factor alpha (TGFalpha)-stimulated secretion of HSP90alpha: using the receptor LRP-1/CD91 to promote human skin cell migration against a TGFbeta-rich environment during wound healing | Q39024877 | ||
| Chemokine-containing exosomes are released from heat-stressed tumor cells via lipid raft-dependent pathway and act as efficient tumor vaccine | Q39606728 | ||
| Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression. | Q39609173 | ||
| Secretion of the heat shock proteins HSP70 and HSC70 by baby hamster kidney (BHK-21) cells | Q39702031 | ||
| Identification of Cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase | Q39791249 | ||
| GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib | Q39807121 | ||
| MHC independent anti-tumor immune responses induced by Hsp70-enriched exosomes generate tumor regression in murine models | Q39911851 | ||
| Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages. | Q40005411 | ||
| Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis. | Q40158449 | ||
| Heat shock protein 70 is secreted from tumor cells by a nonclassical pathway involving lysosomal endosomes | Q40206569 | ||
| Extracellular heat shock protein-70 induces endotoxin tolerance in THP-1 cells. | Q40212489 | ||
| P275 | copyright license | Creative Commons Attribution | Q6905323 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | heat shock proteins | Q418939 |
| extracellular exosome | Q903634 | ||
| neoplasm | Q1216998 | ||
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P577 | publication date | 2017-04-29 | |
| P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
| P1476 | title | Unconventional Secretion of Heat Shock Proteins in Cancer | |
| P478 | volume | 18 |
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