scholarly article | Q13442814 |
P2093 | author name string | Reena Ghildyal | |
Cynthia Mathew | |||
P2860 | cites work | Emerging roles for the influenza A virus nuclear export protein (NEP) | Q21089600 |
Transport between the cell nucleus and the cytoplasm | Q22065411 | ||
Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication | Q24309486 | ||
Influenza B and C virus NEP (NS2) proteins possess nuclear export activities | Q24529536 | ||
Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway | Q24653458 | ||
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region | Q24685870 | ||
Structural Basis of Targeting the Exportin CRM1 in Cancer | Q26781513 | ||
Nuclear export of proteins and drug resistance in cancer | Q27012444 | ||
Recent Advances in Deciphering Viral and Host Determinants of Dengue Virus Replication and Pathogenesis | Q27477646 | ||
CRM1-mediated Nuclear Export of Dengue Virus RNA Polymerase NS5 Modulates Interleukin-8 Induction and Virus Production | Q27488888 | ||
Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP | Q27655147 | ||
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1 | Q27675810 | ||
Inhibition of nuclear export of ribonucleoprotein complexes of influenza virus by leptomycin B. | Q27863701 | ||
Assembly and budding of influenza virus | Q27863797 | ||
Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex | Q27863801 | ||
Nuclear traffic of influenza virus proteins and ribonucleoprotein complexes | Q27864127 | ||
HTLV-1 Rex Tunes the Cellular Environment Favorable for Viral Replication | Q28066382 | ||
Nucleocytoplasmic transport: the soluble phase | Q28131723 | ||
A role for Rev in the association of HIV-1 gag mRNA with cytoskeletal beta-actin and viral protein expression | Q28238195 | ||
Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression | Q28250231 | ||
APC mutations occur early during colorectal tumorigenesis | Q28274764 | ||
Taxonomy of the order Mononegavirales: update 2016 | Q28275807 | ||
Nucleocytoplasmic transport | Q28275907 | ||
Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1 | Q28277890 | ||
The root extract of the medicinal plant Pelargonium sidoides is a potent HIV-1 attachment inhibitor | Q28539308 | ||
In vitro anti-influenza virus activities of a new lignan glycoside from the latex of Calotropis gigantea | Q28541723 | ||
Phase I trial of elactocin | Q36135821 | ||
A novel nuclear trafficking module regulates the nucleocytoplasmic localization of the rabies virus interferon antagonist, P protein | Q36201908 | ||
Viral interactions with the nuclear transport machinery: discovering and disrupting pathways | Q36203647 | ||
NESdb: a database of NES-containing CRM1 cargoes | Q36234505 | ||
Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cells in vivo | Q36395163 | ||
Central role of the respiratory syncytial virus matrix protein in infection. | Q36566590 | ||
CRM1 inhibitor S109 suppresses cell proliferation and induces cell cycle arrest in renal cancer cells | Q36627593 | ||
"Spicing up" of the immune system by curcumin | Q36702820 | ||
Anti- and proinflammatory effects of 15-deoxy-delta-prostaglandin J2(15d-PGJ2) on human eosinophil functions. | Q36836542 | ||
Identification of nuclear export inhibitors with potent anticancer activity in vivo | Q37081966 | ||
Viral subversion of the nuclear pore complex | Q37142582 | ||
Tegument proteins of human cytomegalovirus | Q37183914 | ||
The respiratory syncytial virus matrix protein possesses a Crm1-mediated nuclear export mechanism | Q37191929 | ||
Involvement of the rabies virus phosphoprotein gene in neuroinvasiveness | Q37254274 | ||
CRM1-mediated nuclear export of proteins and drug resistance in cancer | Q37320237 | ||
Human multiple myeloma cells are sensitized to topoisomerase II inhibitors by CRM1 inhibition | Q37347745 | ||
Major human cytomegalovirus structural protein pp65 (ppUL83) prevents interferon response factor 3 activation in the interferon response | Q37568171 | ||
KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia. | Q37693609 | ||
Protein localization in disease and therapy. | Q37947248 | ||
Protein-protein interactions in RSV assembly: potential targets for attenuating RSV strains. | Q37984106 | ||
Overview of the therapeutic potential of piplartine (piperlongumine). | Q38067223 | ||
Promising SINEs for embargoing nuclear-cytoplasmic export as an anticancer strategy | Q38205335 | ||
Clinical translation of nuclear export inhibitors in cancer | Q38206324 | ||
Selective inhibitors of nuclear export (SINE)--a novel class of anti-cancer agents | Q38260357 | ||
Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone-refractory prostate cancer | Q38359505 | ||
Selective inhibitors of nuclear export (SINE) in hematological malignancies | Q38368605 | ||
The dengue virus NS5 protein as a target for drug discovery | Q38442511 | ||
The antiviral and antimicrobial activities of licorice, a widely-used Chinese herb | Q38636996 | ||
CBS9106-induced CRM1 degradation is mediated by cullin ring ligase activity and the neddylation pathway. | Q38953484 | ||
CRM1 is a direct cellular target of the natural anti-cancer agent plumbagin | Q39003453 | ||
Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells. | Q39004520 | ||
The myxobacterial metabolite ratjadone A inhibits HIV infection by blocking the Rev/CRM1-mediated nuclear export pathway. | Q39029310 | ||
CRM1 is a cellular target of curcumin: new insights for the myriad of biological effects of an ancient spice | Q39129924 | ||
Water extract of licorice had anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines | Q39156494 | ||
CRM1 and BRAF inhibition synergize and induce tumor regression in BRAF-mutant melanoma | Q39161114 | ||
Antiviral activity of Isatis indigotica root-derived clemastanin B against human and avian influenza A and B viruses in vitro | Q39195555 | ||
Ge-Gen-Tang has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines | Q39436827 | ||
Nuclear Export as a Novel Therapeutic Target: The CRM1 Connection | Q29036286 | ||
Transport into and out of the nucleus | Q29615611 | ||
Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle | Q29619289 | ||
Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA | Q29620175 | ||
Challenges and opportunities in developing respiratory syncytial virus therapeutics | Q30300567 | ||
Verdinexor, a novel selective inhibitor of nuclear export, reduces influenza a virus replication in vitro and in vivo. | Q30363986 | ||
14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport | Q33292269 | ||
Piperlongumine inhibits NF-κB activity and attenuates aggressive growth characteristics of prostate cancer cells | Q33738321 | ||
Piperlongumine inhibits migration of glioblastoma cells via activation of ROS-dependent p38 and JNK signaling pathways | Q33748476 | ||
Role of the influenza virus M1 protein in nuclear export of viral ribonucleoproteins | Q33797502 | ||
Production of HIV particles is regulated by altering sub-cellular localization and dynamics of Rev induced by double-strand RNA binding protein | Q33834106 | ||
The Thr205 phosphorylation site within respiratory syncytial virus matrix (M) protein modulates M oligomerization and virus production | Q33887779 | ||
Atomic basis of CRM1-cargo recognition, release and inhibition | Q33940712 | ||
Toward antiviral strategies that resist viral escape | Q33979280 | ||
Curcumin: the Indian solid gold | Q34004696 | ||
Crossing the nuclear envelope: hierarchical regulation of nucleocytoplasmic transport | Q34008468 | ||
KPT-330 inhibitor of XPO1-mediated nuclear export has anti-proliferative activity in hepatocellular carcinoma | Q34098446 | ||
Emerging anticancer potentials of goniothalamin and its molecular mechanisms. | Q34177051 | ||
CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity | Q34207970 | ||
A synthetic HIV-1 Rev inhibitor interfering with the CRM1-mediated nuclear export | Q34394284 | ||
Inhibition of CRM1-dependent nuclear export sensitizes malignant cells to cytotoxic and targeted agents | Q34410193 | ||
Nucleo-cytoplasmic transport as a therapeutic target of cancer | Q34452108 | ||
Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning | Q34554323 | ||
Curcumin disrupts the Mammalian target of rapamycin-raptor complex. | Q34603763 | ||
Influenza A virus NS2 protein mediates vRNP nuclear export through NES-independent interaction with hCRM1 | Q34685189 | ||
Preclinical evaluation of the novel, orally bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in spontaneous canine cancer: results of a phase I study | Q35087639 | ||
Nuclear envelope and genome interactions in cell fate | Q35194606 | ||
Black cumin (Nigella sativa) and its constituent (thymoquinone): a review on antimicrobial effects | Q35288598 | ||
Protein quality control at the inner nuclear membrane | Q35527818 | ||
Infectious disease. Combating emerging viral threats | Q35569547 | ||
Physiology and pharmacology of the prostaglandin J2 family | Q35616285 | ||
Piperlongumine is a novel nuclear export inhibitor with potent anticancer activity | Q35647146 | ||
Characterization of BRCA1 protein targeting, dynamics, and function at the centrosome: a role for the nuclear export signal, CRM1, and Aurora A kinase | Q35801868 | ||
A nuclear export signal in the matrix protein of Influenza A virus is required for efficient virus replication | Q35943682 | ||
The human T-cell leukemia virus Rex protein | Q35969160 | ||
Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. | Q39457088 | ||
Liu-He-Tang inhibited plaque formation by human respiratory syncytial virus infection in cell lines of the human respiratory tract | Q39496308 | ||
Sheng-Ma-Ge-Gen-Tang (Shoma-kakkon-to) inhibited cytopathic effect of human respiratory syncytial virus in cell lines of human respiratory tract | Q39564800 | ||
The phosphoprotein of rabies virus is phosphorylated by a unique cellular protein kinase and specific isomers of protein kinase C | Q39588524 | ||
Interaction of the influenza virus nucleoprotein with the cellular CRM1-mediated nuclear export pathway | Q39601251 | ||
Plumbagin-induced apoptosis of human breast cancer cells is mediated by inactivation of NF-kappaB and Bcl-2. | Q39922091 | ||
MD-2 as the target of curcumin in the inhibition of response to LPS. | Q40112020 | ||
Goniothalamin induces cell cycle-specific apoptosis by modulating the redox status in MDA-MB-231 cells | Q40366203 | ||
Identification of the rabies virus alpha/beta interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3. | Q40416432 | ||
Crm1 is a mitotic effector of Ran-GTP in somatic cells | Q40418909 | ||
Nucleocytoplasmic shuttling of the rabies virus P protein requires a nuclear localization signal and a CRM1-dependent nuclear export signal | Q40444617 | ||
Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection. | Q40448705 | ||
CRM1-dependent nuclear export of dengue virus type 2 NS5. | Q40457090 | ||
The cytoplasmic trafficking of DNA topoisomerase IIalpha correlates with etoposide resistance in human myeloma cells | Q40565443 | ||
Multi parameter in vitro testing of ratjadone using flow cytometry | Q40657878 | ||
New Rev-transport inhibitor with anti-HIV activity from Valerianae Radix | Q40702077 | ||
The CRM1 nuclear export protein in normal development and disease. | Q41860863 | ||
Nuclear export of the human cytomegalovirus tegument protein pp65 requires cyclin-dependent kinase activity and the Crm1 exporter | Q41994064 | ||
The anti-inflammatory prostaglandin 15-deoxy-delta(12,14)-PGJ2 inhibits CRM1-dependent nuclear protein export | Q42057495 | ||
Fission yeast pap1-dependent transcription is negatively regulated by an essential nuclear protein, crm1 | Q42140112 | ||
Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover | Q42796363 | ||
The nucleocytoplasmic rabies virus P protein counteracts interferon signaling by inhibiting both nuclear accumulation and DNA binding of STAT1. | Q42797122 | ||
Ratjadones inhibit nuclear export by blocking CRM1/exportin 1. | Q42801742 | ||
Prenylcoumarin with Rev-export inhibitory activity from Cnidii Monnieris Fructus | Q43056689 | ||
The cytotoxic styryl lactone goniothalamin is an inhibitor of nucleocytoplasmic transport | Q43104351 | ||
Bioisostere of valtrate, anti-HIV principle by inhibition for nuclear export of Rev. | Q43140683 | ||
Anguinomycins and derivatives: total syntheses, modeling, and biological evaluation of the inhibition of nucleocytoplasmic transport | Q43200620 | ||
Nucleocytoplasmic shuttling and CRM1-dependent MHC class I peptide presentation of human cytomegalovirus pp65. | Q44245356 | ||
HIV-1 Rev and related inhibitors | Q44477426 | ||
Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia | Q44666530 | ||
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells | Q44714283 | ||
Ratjadone and leptomycin B block CRM1-dependent nuclear export by identical mechanisms. | Q45097896 | ||
The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation. | Q46668855 | ||
Human cytomegalovirus UL94 is a nucleocytoplasmic shuttling protein containing two NLSs and one NES. | Q48025655 | ||
CRM1-mediated nuclear export: to the pore and beyond. | Q50336102 | ||
Human cytomegalovirus protein pp65 mediates accumulation of HLA-DR in lysosomes and destruction of the HLA-DR alpha-chain. | Q54786854 | ||
Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus | Q56956215 | ||
Cytotoxicity and antimicrobial activity of goniothalamin isolated fromBryonopsis laciniosa | Q57931787 | ||
Cytomegalovirus selectively blocks antigen processing and presentation of its immediate–early gene product | Q59098221 | ||
Synergistic stimulation of HIV-1 rev-dependent export of unspliced mRNA to the cytoplasm by hnRNP A1 | Q77928316 | ||
Nuclear and cytoplasmic effects of human CRM1 on HIV-1 production in rat cells | Q83248574 | ||
Anti-influenza viral effects of novel nuclear export inhibitors from Valerianae Radix and Alpinia galanga | Q83784151 | ||
[Organization and regulation of nucleocytoplasmic transport] | Q84496516 | ||
Inhibiting cancer cell hallmark features through nuclear export inhibition | Q89700428 | ||
P304 | page(s) | 1171 | |
P577 | publication date | 2017-06-28 | |
P1433 | published in | Frontiers in Microbiology | Q27723481 |
P1476 | title | CRM1 Inhibitors for Antiviral Therapy | |
P478 | volume | 8 |
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