Depletion of GRIM-19 accelerates hepatocellular carcinoma invasion via inducing EMT and loss of contact inhibition

scientific article

Depletion of GRIM-19 accelerates hepatocellular carcinoma invasion via inducing EMT and loss of contact inhibition is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JCP.24025
P698PubMed publication ID22105514

P2093author name stringXiuqing Zhang
Yang Yang
Jun Liu
Qian Liu
Xinmin Cao
Guoliang Liu
Hongbo Hao
Dongshi Guan
P2860cites workIdentification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approachQ22254731
Epithelial-mesenchymal transitions in tumour progressionQ27860487
Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasisQ28283104
Hepatocellular carcinoma: epidemiology and molecular carcinogenesisQ28306363
Complex networks orchestrate epithelial-mesenchymal transitionsQ29547478
Down-regulation of GRIM-19 expression is associated with hyperactivation of STAT3-induced gene expression and tumor growth in human cervical cancersQ34334192
Tumor suppressive protein gene associated with retinoid-interferon-induced mortality (GRIM)-19 inhibits src-induced oncogenic transformation at multiple levelsQ36007492
New signals from the invasive frontQ36488744
Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.Q36615843
GRIM-19 inhibits v-Src-induced cell motility by interfering with cytoskeletal restructuringQ37143935
Gene associated with retinoid-interferon-induced mortality-19 suppresses growth of lung adenocarcinoma tumor in vitro and in vivoQ39637333
Overexpression of GRIM-19 in Cancer Cells Suppresses STAT3-Mediated Signal Transduction and Cancer GrowthQ39672011
Upregulation of the GRIM-19 gene suppresses invasion and metastasis of human gastric cancer SGC-7901 cell lineQ39703120
Effects of plasmid-based Stat3-specific short hairpin RNA and GRIM-19 on PC-3M tumor cell growthQ40020168
A proteomic analysis reveals the loss of expression of the cell death regulatory gene GRIM-19 in human renal cell carcinomasQ40274291
Point mutation in GRIM-19: a new genetic lesion in Hurthle cell thyroid carcinomasQ43200914
Diagnosis and Treatment of Hepatocellular CarcinomaQ56172242
P433issue3
P407language of work or nameEnglishQ1860
P921main subjecthepatocellular carcinomaQ1148337
P304page(s)1212-1219
P577publication date2012-03-01
P1433published inJournal of Cellular PhysiologyQ1524270
P1476titleDepletion of GRIM-19 accelerates hepatocellular carcinoma invasion via inducing EMT and loss of contact inhibition
P478volume227

Reverse relations

cites work (P2860)
Q38828603Additive effects of eukaryotic co‑expression plasmid carrying GRIM‑19 and LKB1 genes on breast cancer in vitro and in vivo
Q35238408Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma
Q38962203GRIM-19: A master regulator of cytokine induced tumor suppression, metastasis and energy metabolism
Q39243010HBx-dependent activation of Twist mediates STAT3 control of epithelium-mesenchymal transition of liver cells
Q43449411MicroRNA-491 is involved in metastasis of hepatocellular carcinoma by inhibitions of matrix metalloproteinase and epithelial to mesenchymal transition
Q37318166Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice
Q34733212Overexpression of GRIM-19, a mitochondrial respiratory chain complex I protein, suppresses hepatocellular carcinoma growth.
Q44973273Synergistic effects of co-expression plasmid‑based ADAM10-specific siRNA and GRIM-19 on hepatocellular carcinoma in vitro and in vivo
Q36685267Tumor-derived mutations in the gene associated with retinoid interferon-induced mortality (GRIM-19) disrupt its anti-signal transducer and activator of transcription 3 (STAT3) activity and promote oncogenesis
Q38877630Upregulation of GRIM-19 inhibits the growth and invasion of human breast cancer cells

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