Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light

scientific article

Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.19.1.147
P932PMC publication ID83873
P698PubMed publication ID9858539
P5875ResearchGate publication ID13428349

P2093author name stringV M Maher
W G McGregor
J J McCormick
D Wei
P2860cites workCloning of the cDNAs for the small subunits of bovine and human DNA polymerase delta and chromosomal location of the human gene (POLD2)Q24312065
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Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in the coding region of the HPRT geneQ33885580
The specificity of UV-induced mutations at an endogenous locus in mammalian cellsQ34379440
Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiationQ35067081
Fork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templatesQ35929087
REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymeraseQ36182950
Replication of UV-irradiated DNA in human cell extracts: evidence for mutagenic bypass of pyrimidine dimersQ36487817
Strand specificity of mutagenic bypass replication of DNA containing psoralen monoadducts in a human cell extractQ36559799
Replication and mutagenesis of UV-damaged DNA templates in human and monkey cell extractsQ36659778
Cell cycle-dependent strand bias for UV-induced mutations in the transcribed strand of excision repair-proficient human fibroblasts but not in repair-deficient cellsQ36688064
Evidence from mutation spectra that the UV hypermutability of xeroderma pigmentosum variant cells reflects abnormal, error-prone replication on a template containing photoproductsQ36690666
Replication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesisQ36861158
Simian virus 40 DNA replication in vitro: specificity of initiation and evidence for bidirectional replicationQ36889856
Sequence specificity of point mutations induced during passage of a UV-irradiated shuttle vector plasmid in monkey cellsQ36908922
Postreplication repair: questions of its definition and possible alteration in xeroderma pigmentosum cell strainsQ37340059
DNA strand specificity for UV-induced mutations in mammalian cellsQ40646667
Malignant transformation of a human fibroblast cell strain by transfection of a v-fes oncogene but not by transfection of a gag-human c-fes constructQ41424832
Statistical test for the comparison of samples from mutational spectraQ41430602
Relationship between excision repair and the cytotoxic and mutagenic effect of the 'anti' 7,8-diol-9,10-epoxide of benzo[a]pyrene in human cellsQ41602236
Characteristics of an infinite life span diploid human fibroblast cell strain and a near-diploid strain arising from a clone of cells expressing a transfected v-myc oncogeneQ41657753
Molecular analysis of ultraviolet-induced mutations in a xeroderma pigmentosum cell lineQ41699264
Xeroderma pigmentosum. An inherited diseases with sun sensitivity, multiple cutaneous neoplasms, and abnormal DNA repairQ42440575
Yeast ARS function and nuclear matrix association coincide in a short sequence from the human HPRT locusQ48324764
Comparison of the rate of excision of major UV photoproducts in the strands of the human HPRT gene of normal and xeroderma pigmentosum variant cells.Q53457247
Excision repair of UV- or benzo[a]pyrene diol epoxide-induced lesions in xeroderma pigmentosum variant cells is 'error free'.Q54441753
DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall.Q54455838
Ultraviolet mutagenesis of normal and xeroderma pigmentosum variant human fibroblastsQ54567448
DNA excision-repair processes in human cells can eliminate the cytotoxic and mutagenic consequences of ultraviolet irradiationQ54567450
Xeroderma pigmentosum: variants with normal DNA repair and normal sensitivity to ultraviolet lightQ57971918
Frequency of ultraviolet light-induced mutations is higher in xeroderma pigmentosum variant cells than in normal human cellsQ59097788
Defective postreplication repair in xeroderma pigmentosum variant fibroblastsQ67285583
Alternative Dideoxy Sequencing of Double-Stranded DNA by Cyclic Reactions Using Taq PolymeraseQ68291695
Modification of MCDB 110 medium to support prolonged growth and consistent high cloning efficiency of diploid human fibroblastsQ69397371
DNA sequence analysis of the mutational specificity of u.v. light in the SUP4-o gene of yeastQ69822487
Extent of excision repair before DNA synthesis determines the mutagenic but not the lethal effect of UV radiationQ70434672
Complete replication of plasmid DNA containing a single UV-induced lesion in human cell extractsQ71058877
Xeroderma pigmentosum fibroblasts including cells from XP variants are abnormally sensitive to the mutagenic and cytotoxic action of broad spectrum simulated sunlightQ71282096
Frequency and Fidelity of Translesion Synthesis of Site-specific N-2-Acetylaminofluorene Adducts during DNA Replication in a Human Cell ExtractQ72054893
Relative probability of mutagenic translesion synthesis on the leading and lagging strands during replication of UV-irradiated DNA in a human cell extractQ72551652
Differential replication of a single N-2-acetylaminofluorene lesion in the leading or lagging strand DNA in a human cell extractQ73413502
Defective bypass replication of a leading strand cyclobutane thymine dimer in xeroderma pigmentosum variant cell extractsQ74632874
P4510describes a project that usesImageQuantQ112270642
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectxeroderma pigmentosumQ612693
biasQ742736
P304page(s)147-154
P577publication date1999-01-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleAbnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light
P478volume19

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