Translesion synthesis by the UmuC family of DNA polymerases

scientific article

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Translesion synthesis by the UmuC family of DNA polymerases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0921-8777(01)00089-1
P698PubMed publication ID11425512

P2093author name stringWang Z
P2860cites workMutagenic Specificity of (Acetylamino)fluorene-Derived DNA Adducts in Mammalian CellsQ77182633
hRAD30 mutations in the variant form of xeroderma pigmentosumQ22010237
The human REV1 gene codes for a DNA template-dependent dCMP transferaseQ22010721
Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein dinBQ22011012
Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagensQ22254567
The human RAD18 gene product interacts with HHR6A and HHR6BQ22254654
A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase ζQ24323043
Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6Q24337556
All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesisQ24597093
Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iotaQ24597750
Multiple pathways for SOS-induced mutagenesis in Escherichia coli: an overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNAQ24628966
Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamilyQ24673479
Mechanisms of accurate translesion synthesis by human DNA polymerase etaQ24678700
The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV lightQ24681973
The human DINB1 gene encodes the DNA polymerase PolthetaQ24683573
Deoxycytidyl transferase activity of yeast REV1 proteinQ27931173
Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase eta.Q27931739
Specificity of DNA lesion bypass by the yeast DNA polymerase eta.Q27933149
The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzymeQ27933609
Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, PoletaQ27935465
Thymine-thymine dimer bypass by yeast DNA polymerase zetaQ27938043
Yeast DNA Repair Proteins Rad6 and Rad18 Form a Heterodimer That Has Ubiquitin Conjugating, DNA Binding, and ATP Hydrolytic ActivitiesQ27938794
Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sitesQ27938885
Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sitesQ27939478
The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase etaQ28115711
Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase etaQ28116380
A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2Q28144150
Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitroQ28646677
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodGQ29616532
Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesionsQ29619958
Pol kappa: A DNA polymerase required for sister chromatid cohesion.Q30305921
The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replicationQ31422789
Analysis of Damage Tolerance Pathways in Saccharomyces cerevisiae: a Requirement for Rev3 DNA Polymerase in Translesion SynthesisQ33771455
Human DNA polymerase kappa synthesizes DNA with extraordinarily low fidelityQ33826153
A full-length cDNA of hREV3 is predicted to encode DNA polymerase zeta for damage-induced mutagenesis in humansQ33856770
Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 geneQ33920689
DNA damage-induced mutation: tolerance via translesion synthesisQ33984301
The SOS response: recent insights into umuDC-dependent mutagenesis and DNA damage toleranceQ34090796
The expanding polymerase universeQ34186298
Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesisQ34964296
UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V.Q35588920
The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidanceQ36099918
The REV1 gene of Saccharomyces cerevisiae: isolation, sequence, and functional analysisQ36172976
REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymeraseQ36182950
RAD6 gene of Saccharomyces cerevisiae encodes a protein containing a tract of 13 consecutive aspartatesQ37672743
Mutagenic Potential of Stereoisomeric Bay Region (+)- and (−)-cis-anti-Benzo[a]pyrene Diol Epoxide-N2-2‘-deoxyguanosine Adducts in Escherichia coli and Simian Kidney CellsQ38335495
Response of human DNA polymerase iota to DNA lesionsQ38658428
Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV lightQ39444340
Impaired translesion synthesis in xeroderma pigmentosum variant extractsQ39444921
Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iotaQ39455619
Requirement of DNA polymerase eta for error-free bypass of UV-induced CC and TC photoproductsQ39468393
Error-prone lesion bypass by human DNA polymerase eta.Q39607351
The (6-4) photoproduct of thymine-thymine induces targeted substitution mutations in mammalian cellsQ39723958
The Saccharomyces cerevisiae RAD18 gene encodes a protein that contains potential zinc finger domains for nucleic acid binding and a putative nucleotide binding sequenceQ40554098
The RAD6 DNA repair pathway in Saccharomyces cerevisiae: what does it do, and how does it do it?Q40671595
Somatic hypermutation of immunoglobulin genesQ40955728
Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesisQ41734679
Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activityQ41869549
Potential DNA-binding domains in the RAD18 gene product of Saccharomyces cerevisiaeQ42653401
Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 geneQ45345090
Deletion of the Saccharomyces cerevisiae gene RAD30 encoding an Escherichia coli DinB homolog confers UV radiation sensitivity and altered mutability.Q48033074
Low fidelity DNA synthesis by human DNA polymerase-etaQ50335566
Disruption of the developmentally regulated Rev3l gene causes embryonic lethalityQ52163744
Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitroQ52541352
Disruption of the Rev3l-encoded catalytic subunit of polymerase zeta in mice results in early embryonic lethality.Q52541355
Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase eta.Q54055057
Novel Mutagenic Properties of Abasic Sites inSaccharomyces cerevisiaeQ54606410
Frequency of ultraviolet light-induced mutations is higher in xeroderma pigmentosum variant cells than in normal human cellsQ59097788
REV7, a new gene concerned with UV mutagenesis in yeastQ69905798
Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chiralityQ71955465
Effect of umuC mutations on targeted and untargeted ultraviolet mutagenesis in bacteriophage λQ72820392
The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesisQ72994394
POL32, a subunit of the Saccharomyces cerevisiae DNA polymerase delta, defines a link between DNA replication and the mutagenic bypass repair pathwayQ73319794
Fidelity of human DNA polymerase etaQ73538274
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)59-70
P577publication date2001-07-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inMutation ResearchQ6943732
P1476titleTranslesion synthesis by the UmuC family of DNA polymerases
P478volume486

Reverse relations

cites work (P2860)
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