scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.275.11.7447 |
P698 | PubMed publication ID | 10713043 |
P50 | author | Todd Washington | Q73118418 |
P2093 | author name string | L Prakash | |
S Prakash | |||
R E Johnson | |||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 7447-7450 | |
P577 | publication date | 2000-03-01 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Fidelity of human DNA polymerase eta | |
P478 | volume | 275 |
Q28587504 | 129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation |
Q40240453 | 8-Hydroxyguanine in a mutational hotspot of the c-Ha-ras gene causes misreplication, 'action-at-a-distance' mutagenesis and inhibition of replication |
Q36783631 | A high-throughput and quantitative method to assess the mutagenic potential of translesion DNA synthesis |
Q24646838 | A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair |
Q40493478 | A method to monitor replication fork progression in mammalian cells: nucleotide excision repair enhances and homologous recombination delays elongation along damaged DNA. |
Q37326124 | A novel POLH mutation causes XP-V disease and XP-V tumor proneness may involve imbalance of numerous DNA polymerases. |
Q37406038 | A real-time fluorescence method for enzymatic characterization of specialized human DNA polymerases |
Q36315292 | A role for yeast and human translesion synthesis DNA polymerases in promoting replication through 3-methyl adenine |
Q33714583 | A single domain in human DNA polymerase iota mediates interaction with PCNA: implications for translesion DNA synthesis |
Q43509472 | A single highly mutable catalytic site amino acid is critical for DNA polymerase fidelity |
Q40669326 | A single site-specific trans-opened 7,8,9,10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct induces mutations at multiple sites in DNA. |
Q36619097 | A strategy for the expression of recombinant proteins traditionally hard to purify |
Q35068183 | AID to overcome the limitations of genomic information by introducing somatic DNA alterations |
Q40463112 | ASFV DNA polymerse X is extremely error-prone under diverse assay conditions and within multiple DNA sequence contexts |
Q41720039 | Aberrant Kynurenine Signaling Modulates DNA Replication Stress Factors and Promotes Genomic Instability in Gliomas |
Q42579444 | Acceleration of 5-methylcytosine deamination in cyclobutane dimers by G and its implications for UV-induced C-to-T mutation hotspots |
Q27938785 | Accessibility of DNA polymerases to repair synthesis during nucleotide excision repair in yeast cell-free extracts |
Q37097247 | Accuracy of lesion bypass by yeast and human DNA polymerase eta. |
Q39458346 | Acidic residues critical for the activity and biological function of yeast DNA polymerase eta. |
Q49411576 | Age Is Relative-Impact of Donor Age on Induced Pluripotent Stem Cell-Derived Cell Functionality |
Q24535441 | Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template. |
Q44367170 | Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. |
Q42157040 | Architecture of Y‐Family DNA Polymerases Relevant to Translesion DNA Synthesis as Revealed in Structural and Molecular Modeling Studies |
Q40686398 | Asymmetry of DNA replication and translesion synthesis of UV-induced thymine dimers |
Q27671647 | Basis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA Polymerases |
Q35780144 | Beyond translesion synthesis: polymerase κ fidelity as a potential determinant of microsatellite stability |
Q36893377 | Biochemical analysis of active site mutations of human polymerase η |
Q91752832 | Biochemical reconstitution of UV-induced mutational processes |
Q46465906 | Cancer in xeroderma pigmentosum and related disorders of DNA repair |
Q38630779 | Characterization of Escherichia coli UmuC active-site loops identifies variants that confer UV hypersensitivity |
Q34155778 | Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana. |
Q35963618 | Checkpoint activation regulates mutagenic translesion synthesis |
Q40773301 | Chemical synthesis and translesion replication of a cis-syn cyclobutane thymine-uracil dimer |
Q45722526 | Cloning and characterization of DNA polymerase eta from Trypanosoma cruzi: roles for translesion bypass of oxidative damage |
Q36417607 | Comparative Molecular Dynamics Studies of Human DNA Polymerase η. |
Q34097492 | Complex formation of yeast Rev1 and Rev7 proteins: a novel role for the polymerase-associated domain |
Q35221381 | Complex formation with Rev1 enhances the proficiency of Saccharomyces cerevisiae DNA polymerase zeta for mismatch extension and for extension opposite from DNA lesions |
Q27634747 | Crystal structure of a DinB lesion bypass DNA polymerase catalytic fragment reveals a classic polymerase catalytic domain |
Q27635332 | Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication |
Q34375816 | DNA lesion bypass polymerases open up. |
Q35088992 | DNA lesion identity drives choice of damage tolerance pathway in murine cell chromosomes |
Q28190856 | DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes |
Q33935129 | DNA polymerase eta lacking the ubiquitin-binding domain promotes replicative lesion bypass in humans cells |
Q40777650 | DNA polymerase eta undergoes alternative splicing, protects against UV sensitivity and apoptosis, and suppresses Mre11-dependent recombination |
Q24523653 | DNA polymerase iota and related rad30-like enzymes |
Q37084895 | DNA polymerases and cancer. |
Q34360690 | DNA polymerases and somatic hypermutation of immunoglobulin genes |
Q35978843 | DNA polymerases eta and iota |
Q38707053 | DNA replication stress: from molecular mechanisms to human disease |
Q37122141 | DNA-damage tolerance mediated by PCNA*Ub fusions in human cells is dependent on Rev1 but not Polη. |
Q39743644 | Deoxynucleotide triphosphate binding mode conserved in Y family DNA polymerases |
Q33933937 | Distinct mechanisms of cis-syn thymine dimer bypass by Dpo4 and DNA polymerase eta |
Q38304800 | Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells |
Q47785542 | Dpo4 is hindered in extending a G.T mismatch by a reverse wobble |
Q33289766 | Effects of accessory proteins on the bypass of a cis-syn thymine-thymine dimer by Saccharomyces cerevisiae DNA polymerase eta. |
Q21146665 | Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring |
Q36735122 | Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo. |
Q24563650 | Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa |
Q36701342 | Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta. |
Q37509255 | Enzymatic switching for efficient and accurate translesion DNA replication. |
Q34958722 | Error-prone translesion synthesis past DNA-peptide cross-links conjugated to the major groove of DNA via C5 of thymidine |
Q37044564 | Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA. |
Q29619958 | Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions |
Q33924989 | Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa |
Q36380466 | Evidence for the kinetic partitioning of polymerase activity on G-quadruplex DNA. |
Q34244261 | Evolution of the two-step model for UV-mutagenesis |
Q35253312 | Exploiting CpG hypermutability to identify phenotypically significant variation within human protein-coding genes |
Q34053164 | Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens |
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Q45345090 | Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene |
Q35047056 | Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. |
Q46076427 | Genome sequence and splice site analysis of low-fidelity DNA polymerases H and I involved in replication of damaged DNA |
Q36395930 | Genomic approaches to DNA repair and mutagenesis |
Q37416480 | Highly error-free role of DNA polymerase eta in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells |
Q39529040 | Highly frequent frameshift DNA synthesis by human DNA polymerase mu |
Q24534772 | Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini |
Q34097175 | Human DNA polymerase iota promotes replication through a ring-closed minor-groove adduct that adopts a syn conformation in DNA. |
Q36222886 | Human DNA polymerase iota utilizes different nucleotide incorporation mechanisms dependent upon the template base. |
Q35127456 | Human DNA polymerase kappa forms nonproductive complexes with matched primer termini but not with mismatched primer termini. |
Q24670499 | Human DNA polymerase kappa uses template-primer misalignment as a novel means for extending mispaired termini and for generating single-base deletions |
Q73794909 | Human DNA repair genes |
Q39898806 | In Vitro Lesion Bypass Studies of O(4)-Alkylthymidines with Human DNA Polymerase η. |
Q36412869 | In-vitro replication studies on O(2)-methylthymidine and O(4)-methylthymidine |
Q31655742 | Inefficient bypass of an abasic site by DNA polymerase eta. |
Q27935721 | Interaction with PCNA is essential for yeast DNA polymerase eta function |
Q24291530 | Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7 |
Q37477870 | Intramolecular telomeric G-quadruplexes dramatically inhibit DNA synthesis by replicative and translesion polymerases, revealing their potential to lead to genetic change |
Q35840281 | Kinetic analysis of the bypass of a bulky DNA lesion catalyzed by human Y-family DNA polymerases. |
Q33247452 | Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations |
Q35978856 | Mammalian Pol kappa: regulation of its expression and lesion substrates. |
Q28209176 | Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cells |
Q42108252 | Mechanism of efficient and accurate nucleotide incorporation opposite 7,8-dihydro-8-oxoguanine by Saccharomyces cerevisiae DNA polymerase eta. |
Q36348337 | Mechanism of nucleotide incorporation opposite a thymine-thymine dimer by yeast DNA polymerase eta. |
Q27677864 | Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η. |
Q24678700 | Mechanisms of accurate translesion synthesis by human DNA polymerase eta |
Q28608973 | Mechanisms of human DNA repair: an update |
Q24597750 | Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iota |
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Q33196452 | Molecular genetics of Xeroderma pigmentosum variant. |
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Q28211799 | Molecular mechanisms of UV-induced mutations as revealed by the study of DNA polymerase eta in human cells |
Q38298148 | Molecular regulation of UV-induced DNA repair |
Q41789554 | Mutagenesis and repair induced by the DNA advanced glycation end product N2-1-(carboxyethyl)-2'-deoxyguanosine in human cells |
Q47072057 | Mutagenic and nonmutagenic bypass of DNA lesions by Drosophila DNA polymerases dpoleta and dpoliota |
Q33997247 | Mutation of the little finger domain in human DNA polymerase η alters fidelity when copying undamaged DNA |
Q36885382 | Mutation rate variation in multicellular eukaryotes: causes and consequences |
Q24536098 | Mutations in human DNA polymerase eta motif II alter bypass of DNA lesions |
Q36247787 | Mutator alleles of yeast DNA polymerase zeta. |
Q43639973 | Mutator effects of overproducing DNA polymerase eta (Rad30) and its catalytically inactive variant in yeast |
Q47747085 | NGS-based analysis of base-substitution signatures created by yeast DNA polymerase eta and zeta on undamaged and abasic DNA templates in vitro. |
Q47143560 | Non-bulky Lesions in Human DNA: the Ways of Formation, Repair, and Replication |
Q34244249 | Nucleotide excision repair "a legacy of creativity". |
Q37731934 | Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae |
Q38339361 | Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa |
Q91625973 | Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis |
Q36483930 | Photobiological Origins of the Field of Genomic Maintenance |
Q24548300 | Physical and functional interactions of human DNA polymerase eta with PCNA |
Q34387678 | Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene |
Q30881342 | Polymerase eta deficiency in the xeroderma pigmentosum variant uncovers an overlap between the S phase checkpoint and double-strand break repair |
Q34078421 | Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. |
Q34139948 | Pre-steady state kinetic studies of the fidelity of nucleotide incorporation by yeast DNA polymerase delta |
Q35400041 | Pre-steady state kinetic studies show that an abasic site is a cognate lesion for the yeast Rev1 protein |
Q44785638 | Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity. |
Q39455619 | Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iota |
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