| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/978-3-319-60733-7_2 |
| P698 | PubMed publication ID | 28840550 |
| P50 | author | Matthieu D Lavigne | Q55447349 |
| P2093 | author name string | Maria Fousteri | |
| Anastasios Liakos | |||
| P2860 | cites work | Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes | Q59058533 |
| Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients | Q36659736 | ||
| Clock-like mutational processes in human somatic cells | Q36666868 | ||
| XPB, a subunit of TFIIH, is a target of the natural product triptolide. | Q36755350 | ||
| Genome-wide kinetics of DNA excision repair in relation to chromatin state and mutagenesis | Q36821453 | ||
| The Cockayne Syndrome Natural History (CoSyNH) study: clinical findings in 102 individuals and recommendations for care. | Q36871119 | ||
| Deconvoluting the context-dependent role for autophagy in cancer | Q36876716 | ||
| Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase | Q36923197 | ||
| Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors | Q37074346 | ||
| Nucleosome dynamics as modular systems that integrate DNA damage and repair | Q37122315 | ||
| DNA repair genes are selectively mutated in diffuse large B cell lymphomas | Q37125781 | ||
| Coordination of dual incision and repair synthesis in human nucleotide excision repair | Q37196140 | ||
| Genomic landscape of DNA repair genes in cancer | Q37269005 | ||
| DNA repair in mammalian cells : Nucleotide excision repair: variations on versatility | Q37372526 | ||
| High-resolution characterization of CPD hotspot formation in human fibroblasts | Q37518592 | ||
| Complete absence of Cockayne syndrome group B gene product gives rise to UV-sensitive syndrome but not Cockayne syndrome | Q37593459 | ||
| DNA polymerases and repair synthesis in NER in human cells | Q37878065 | ||
| DNA repair dysregulation from cancer driver to therapeutic target | Q38061847 | ||
| Transcription-replication encounters, consequences and genomic instability | Q38095707 | ||
| Nucleotide excision repair related gene polymorphisms and genetic susceptibility, chemotherapeutic sensitivity and prognosis of gastric cancer | Q38207440 | ||
| Mechanisms underlying mutational signatures in human cancers | Q38225013 | ||
| Cancer-specific defects in DNA repair pathways as targets for personalized therapeutic approaches | Q38228818 | ||
| Out of balance: R-loops in human disease | Q21144865 | ||
| Epigenetic changes of DNA repair genes in cancer | Q22242858 | ||
| Substantial contribution of extrinsic risk factors to cancer development | Q22251076 | ||
| The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage | Q24301297 | ||
| Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells | Q24302543 | ||
| Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair | Q24310583 | ||
| UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair | Q24310704 | ||
| Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair | Q24310767 | ||
| Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex | Q24310859 | ||
| Cockayne syndrome group B protein enhances elongation by RNA polymerase II | Q24317053 | ||
| Refining the role for adult stem cells as cancer cells of origin | Q38252977 | ||
| Autophagy positively regulates DNA damage recognition by nucleotide excision repair | Q38295332 | ||
| Irofulven cytotoxicity depends on transcription-coupled nucleotide excision repair and is correlated with XPG expression in solid tumor cells | Q38337367 | ||
| A novel method for the genome-wide high resolution analysis of DNA damage | Q38339508 | ||
| Somatic mutation in cancer and normal cells | Q38592662 | ||
| DNA excision repair at telomeres | Q38595733 | ||
| Triptolide Induces Cell Killing in Multidrug-Resistant Tumor Cells via CDK7/RPB1 Rather than XPB or p44. | Q38769813 | ||
| Pharmacological Bypass of Cockayne Syndrome B Function in Neuronal Differentiation | Q38786757 | ||
| Understanding mutagenesis through delineation of mutational signatures in human cancer | Q38840433 | ||
| Nucleotide Excision Repair and Transcriptional Regulation: TFIIH and Beyond. | Q38863237 | ||
| Cockayne syndrome: Clinical features, model systems and pathways | Q38923380 | ||
| Transcription-coupled repair: an update | Q38934194 | ||
| A small molecule screen identifies an inhibitor of DNA repair inducing the degradation of TFIIH and the chemosensitization of tumor cells to platinum. | Q39025993 | ||
| Cockayne Syndrome group B protein interacts with TRF2 and regulates telomere length and stability | Q39294995 | ||
| The CSB repair factor is overexpressed in cancer cells, increases apoptotic resistance, and promotes tumor growth. | Q39364706 | ||
| Uncommon nucleotide excision repair phenotypes revealed by targeted high-throughput sequencing | Q39393194 | ||
| Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light | Q39444340 | ||
| Downregulation of XPF-ERCC1 enhances cisplatin efficacy in cancer cells. | Q39711077 | ||
| XPG stabilizes TFIIH, allowing transactivation of nuclear receptors: implications for Cockayne syndrome in XP-G/CS patients | Q40139706 | ||
| TFIIH is an elongation factor of RNA polymerase I. | Q40395200 | ||
| Role of DNA polymerase eta in the UV mutation spectrum in human cells | Q40663020 | ||
| Integrated targeted sphingolipidomics and transcriptomics reveal abnormal sphingolipid metabolism as a novel mechanism of the hepatotoxicity and nephrotoxicity of triptolide | Q40935022 | ||
| Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts | Q41083522 | ||
| A new UV-sensitive syndrome not belonging to any complementation groups of xeroderma pigmentosum or Cockayne syndrome: siblings showing biochemical characteristics of Cockayne syndrome without typical clinical manifestations | Q41472419 | ||
| Human mutation rate associated with DNA replication timing | Q42085559 | ||
| KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR). | Q42121575 | ||
| DNA repair protects against cutaneous and internal neoplasia: evidence from xeroderma pigmentosum | Q42461615 | ||
| An altered redox balance mediates the hypersensitivity of Cockayne syndrome primary fibroblasts to oxidative stress. | Q42503209 | ||
| Interrogation of Nucleotide Excision Repair Capacity: Impact on Platinum-Based Cancer Therapy | Q42566962 | ||
| High resolution mapping of modified DNA nucleobases using excision repair enzymes. | Q42870396 | ||
| 3D-DIP-Chip: a microarray-based method to measure genomic DNA damage | Q43114888 | ||
| Individual determination of the yield of the main UV-induced dimeric pyrimidine photoproducts in DNA suggests a high mutagenicity of CC photolesions. | Q43591673 | ||
| Ultraviolet-sensitive syndrome cells are defective in transcription-coupled repair of cyclobutane pyrimidine dimers | Q44267645 | ||
| Inhibition of cell survival and invasive potential of colorectal carcinoma cells by the tyrosine kinase inhibitor STI571. | Q44730800 | ||
| A one-hit model of cell death in inherited neuronal degenerations | Q45300872 | ||
| Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation | Q45823928 | ||
| DNA repair, genome stability and cancer: a historical perspective | Q47883620 | ||
| Reduced telomere length in neurodegenerative disorders may suggest shared biology. | Q50604425 | ||
| DNA REPAIR. Drugging DNA repair. | Q51722722 | ||
| New design of nucleotide excision repair (NER) inhibitors for combination cancer therapy. | Q53216317 | ||
| The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. | Q53370119 | ||
| DNA damage stabilizes interaction of CSB with the transcription elongation machinery | Q33204356 | ||
| Targeted inhibition of Replication Protein A reveals cytotoxic activity, synergy with chemotherapeutic DNA-damaging agents, and insight into cellular function | Q33556289 | ||
| Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging | Q33656093 | ||
| TP53 mutations in human cancers: origins, consequences, and clinical use | Q33685392 | ||
| Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair | Q33818854 | ||
| Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane | Q33919468 | ||
| Maintaining genome stability in the nervous system | Q33957193 | ||
| Reduced local mutation density in regulatory DNA of cancer genomes is linked to DNA repair | Q33976821 | ||
| Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription | Q34031653 | ||
| UV damage-induced RNA polymerase II stalling stimulates H2B deubiquitylation | Q34144605 | ||
| DNA repair deficiency in neurodegeneration. | Q34183328 | ||
| HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer | Q34216446 | ||
| R loops: from transcription byproducts to threats to genome stability | Q34271508 | ||
| Causes and consequences of replication stress | Q34394094 | ||
| Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease | Q34407717 | ||
| Evolution of the cancer stem cell model | Q34408981 | ||
| Cockayne syndrome protein A is a transcription factor of RNA polymerase I and stimulates ribosomal biogenesis and growth | Q34417956 | ||
| Understanding nucleotide excision repair and its roles in cancer and ageing. | Q34426055 | ||
| Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma | Q34549516 | ||
| Blinded by the UV light: how the focus on transcription-coupled NER has distracted from understanding the mechanisms of Cockayne syndrome neurologic disease | Q34554610 | ||
| Phenotypic heterogeneity in the XPB DNA helicase gene (ERCC3): xeroderma pigmentosum without and with Cockayne syndrome | Q34562678 | ||
| DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy | Q34564091 | ||
| Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation | Q34627083 | ||
| Reduced RNA polymerase II transcription in extracts of cockayne syndrome and xeroderma pigmentosum/Cockayne syndrome cells | Q34636040 | ||
| The resurgence of platinum-based cancer chemotherapy | Q34649255 | ||
| Sealing of chromosomal DNA nicks during nucleotide excision repair requires XRCC1 and DNA ligase III alpha in a cell-cycle-specific manner | Q34654453 | ||
| Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability | Q34747176 | ||
| Association between ERCC1 and XPA expression and polymorphisms and the response to cisplatin in testicular germ cell tumours. | Q34786179 | ||
| Chemical inhibitor targeting the replication protein A-DNA interaction increases the efficacy of Pt-based chemotherapy in lung and ovarian cancer | Q34849073 | ||
| DNA damage and repair in telomeres: relation to aging | Q34849875 | ||
| Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity | Q35006896 | ||
| Sequence specificity of cyclobutane pyrimidine dimers in DNA treated with solar (ultraviolet B) radiation | Q35011802 | ||
| Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein | Q35037461 | ||
| Cockayne syndrome: defective repair of transcription? | Q24532391 | ||
| A small-cell lung cancer genome with complex signatures of tobacco exposure | Q24600510 | ||
| The DNA-damage response in human biology and disease | Q24606586 | ||
| Mutational heterogeneity in cancer and the search for new cancer-associated genes | Q24606956 | ||
| A comprehensive catalogue of somatic mutations from a human cancer genome | Q24628532 | ||
| Adult neurogenesis in the mammalian brain: significant answers and significant questions | Q24628935 | ||
| Recruitment of the putative transcription-repair coupling factor CSB/ERCC6 to RNA polymerase II elongation complexes | Q24644162 | ||
| Xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome: a complex genotype-phenotype relationship | Q24644678 | ||
| ABCC5, ERCC2, XPA and XRCC1 transcript abundance levels correlate with cisplatin chemoresistance in non-small cell lung cancer cell lines | Q24811443 | ||
| Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions | Q26261171 | ||
| Nucleotide excision repair in eukaryotes | Q26850656 | ||
| Breaking bad: R-loops and genome integrity | Q26858910 | ||
| Treatment of neurodevelopmental disorders in adulthood | Q27000307 | ||
| Mammalian transcription-coupled excision repair | Q27022616 | ||
| Requirement of yeast RAD2, a homolog of human XPG gene, for efficient RNA polymerase II transcription. implications for Cockayne syndrome | Q27933687 | ||
| The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta | Q28115711 | ||
| Genetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes From a Subset of Patients With Familial Colorectal Carcinomas | Q28267038 | ||
| DNA damage and the balance between survival and death in cancer biology | Q28271163 | ||
| Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy | Q28272049 | ||
| UVSSA and USP7, a new couple in transcription-coupled DNA repair | Q28292625 | ||
| Comprehensive molecular characterization of urothelial bladder carcinoma | Q28306864 | ||
| Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer | Q28384025 | ||
| Virtual screening and biological evaluation of inhibitors targeting the XPA-ERCC1 interaction | Q28484387 | ||
| Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9a | Q28504923 | ||
| CSB is a component of RNA pol I transcription | Q28610049 | ||
| A UV-sensitive syndrome patient with a specific CSA mutation reveals separable roles for CSA in response to UV and oxidative DNA damage | Q29541053 | ||
| Signatures of mutational processes in human cancer | Q29547191 | ||
| Transcription-coupled DNA repair: two decades of progress and surprises | Q29614662 | ||
| The role of autophagy in neurodegenerative disease | Q29614834 | ||
| Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer | Q29615679 | ||
| Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG | Q29615716 | ||
| Cellular processing of platinum anticancer drugs | Q29617899 | ||
| Restoration of p53 function leads to tumour regression in vivo | Q29618727 | ||
| Base changes in tumour DNA have the power to reveal the causes and evolution of cancer | Q30249783 | ||
| Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis | Q30435228 | ||
| Reduced levels of XPA, ERCC1 and XPF DNA repair proteins in testis tumor cell lines. | Q30760649 | ||
| Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction. | Q35165995 | ||
| DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer | Q35206363 | ||
| A unique subset of epithelial ovarian cancers with platinum sensitivity and PARP inhibitor resistance | Q35559721 | ||
| Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution | Q35575263 | ||
| Cancer and neurologic degeneration in xeroderma pigmentosum: long term follow-up characterises the role of DNA repair. | Q35605167 | ||
| Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics. | Q35647709 | ||
| A syndrome resembling progeria: A review of two cases | Q35654297 | ||
| Shining a light on xeroderma pigmentosum | Q35757364 | ||
| Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. | Q35894155 | ||
| Nucleosome rearrangement in human chromatin during UV-induced DNA- reapir synthesis | Q35989834 | ||
| Dwarfism with Retinal Atrophy and Deafness | Q36005962 | ||
| Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells | Q36128504 | ||
| Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17. | Q36129113 | ||
| UV-sensitive syndrome | Q36139544 | ||
| Molecular mechanisms of mammalian global genome nucleotide excision repair. | Q36389623 | ||
| DNA damage-induced cell death by apoptosis. | Q36561337 | ||
| Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair | Q36578527 | ||
| Deep phenotyping of 89 xeroderma pigmentosum patients reveals unexpected heterogeneity dependent on the precise molecular defect | Q36658965 | ||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | neurodegeneration | Q1755122 |
| P304 | page(s) | 17-39 | |
| P577 | publication date | 2017-01-01 | |
| P1433 | published in | Advances in Experimental Medicine and Biology | Q4686385 |
| P1476 | title | Nucleotide Excision Repair: From Neurodegeneration to Cancer | |
| P478 | volume | 1007 |
| Q89722956 | Continuous transcription initiation guarantees robust repair of all transcribed genes and regulatory regions |
| Q47146098 | Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate |
| Q64883630 | Integrating the DNA damage and protein stress responses during cancer development and treatment. |
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