| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Roberta Ghidoni | |
| Luisa Benussi | |||
| Anna Paterlini | |||
| P2860 | cites work | Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia | Q24598142 |
| Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS | Q24633692 | ||
| A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD | Q24634583 | ||
| Progranulin gene expression regulates epithelial cell growth and promotes tumor growth in vivo | Q28139070 | ||
| Structure and chromosomal location of the human granulin gene | Q28156645 | ||
| Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21 | Q28253639 | ||
| Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17 | Q28253651 | ||
| The epithelin precursor encodes two proteins with opposing activities on epithelial cell growth | Q28274290 | ||
| Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses | Q28567505 | ||
| Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria | Q29614410 | ||
| Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions | Q30434949 | ||
| Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin | Q30482362 | ||
| The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration | Q30495415 | ||
| Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration | Q30503638 | ||
| MicroRNA-29b regulates the expression level of human progranulin, a secreted glycoprotein implicated in frontotemporal dementia | Q30982718 | ||
| The granulin/epithelin precursor abrogates the requirement for the insulin-like growth factor 1 receptor for growth in vitro. | Q32048245 | ||
| Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during murine development | Q33187938 | ||
| Progranulin is expressed within motor neurons and promotes neuronal cell survival | Q33513028 | ||
| HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulin | Q33576895 | ||
| Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review | Q33726688 | ||
| Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia | Q33859252 | ||
| FTLD-TDP with motor neuron disease, visuospatial impairment and a progressive supranuclear palsy-like syndrome: broadening the clinical phenotype of TDP-43 proteinopathies. A report of three cases | Q33898394 | ||
| Cerebrospinal fluid progranulin levels in patients with different multiple sclerosis subtypes | Q33946311 | ||
| miR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease | Q33947283 | ||
| From genotype to phenotype: two cases of genetic frontotemporal lobar degeneration with premorbid bipolar disorder. | Q48918054 | ||
| Optimal plasma progranulin cutoff value for predicting null progranulin mutations in neurodegenerative diseases: a multicenter Italian study. | Q50980787 | ||
| Progranulin Leu271LeufsX10 is one of the most common FTLD and CBS associated mutations worldwide. | Q51944165 | ||
| Phenotype variability in progranulin mutation carriers: a clinical, neuropsychological, imaging and genetic study. | Q51967426 | ||
| Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family. | Q51970854 | ||
| Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. | Q51971909 | ||
| Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion. | Q51973117 | ||
| Progranulin enhances neural progenitor cell proliferation through glycogen synthase kinase 3β phosphorylation. | Q53250521 | ||
| A novel progranulin mutation causing frontotemporal lobar degeneration with heterogeneous phenotypic expression. | Q53267796 | ||
| Progranulin Mutations are a Common Cause of FTLD in Northern Italy | Q53312338 | ||
| Higher than expected progranulin mutation rate in a case series of Italian FTLD patients. | Q53403937 | ||
| A novel deletion in progranulin gene is associated with FTDP-17 and CBS. | Q53509247 | ||
| Expansion mutation in C9ORF72 does not influence plasma progranulin levels in frontotemporal dementia. | Q54314709 | ||
| Heterogeneity within a large kindred with frontotemporal dementia: A novel progranulin mutation | Q57419060 | ||
| Progranulin genetic variability contributes to amyotrophic lateral sclerosis | Q57838448 | ||
| Phenotypic Heterogeneity of the GRN Asp22fs Mutation in a Large Italian Kindred | Q57898498 | ||
| Progranulin Genetic Screening in Frontotemporal Lobar Degeneration Patients From Central Italy | Q57901400 | ||
| The Progranulin (GRN) Cys157LysfsX97 Mutation is Associated with Nonfluent Variant of Primary Progressive Aphasia Clinical Phenotype | Q57911749 | ||
| Deletion of the progranulin gene in patients with frontotemporal lobar degeneration or Parkinson disease | Q57977576 | ||
| Low Serum Progranulin Predicts the Presence of Mutations: A Prospective Study | Q59544594 | ||
| Clinical and neuropathological criteria for frontotemporal dementia. The Lund and Manchester Groups | Q59549757 | ||
| Progranulin locus deletion in frontotemporal dementia | Q59698065 | ||
| Granulins: the structure and function of an emerging family of growth factors | Q77407040 | ||
| Granulin mutations associated with frontotemporal lobar degeneration and related disorders: an update | Q81430169 | ||
| Progranulin (GRN) in two siblings of a Latino family and in other patients with schizophrenia | Q33955043 | ||
| Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration | Q33999208 | ||
| Soluble beta-amyloid precursor protein is related to disease progression in amyotrophic lateral sclerosis | Q33999870 | ||
| Progranulin gene (GRN) promoter methylation is increased in patients with sporadic frontotemporal lobar degeneration | Q34338059 | ||
| Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin. | Q34346014 | ||
| Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma | Q34381669 | ||
| TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers. | Q34555400 | ||
| TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort | Q34605483 | ||
| rs5848 polymorphism and serum progranulin level | Q34891810 | ||
| Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels | Q34959322 | ||
| Similar clinical and neuroimaging features in monozygotic twin pair with mutation in progranulin | Q35883188 | ||
| Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage | Q36017101 | ||
| Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes | Q36227050 | ||
| No major progranulin genetic variability contribution to disease etiopathogenesis in an ALS Italian cohort | Q36438687 | ||
| Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival | Q36527176 | ||
| Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β. | Q36922853 | ||
| Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia | Q36967985 | ||
| Novel progranulin mutation detected in 2 patients with FTLD. | Q37008874 | ||
| Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members | Q37148011 | ||
| Serum progranulin levels in patients with frontotemporal lobar degeneration and Alzheimer's disease: detection of GRN mutations in a Spanish cohort. | Q38470633 | ||
| Symmetrical corticobasal syndrome caused by a novel C.314dup progranulin mutation | Q38922949 | ||
| Pathogenic cysteine mutations affect progranulin function and production of mature granulins | Q39760142 | ||
| Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration. | Q40051471 | ||
| Intra-familial clinical heterogeneity due to FTLD-U with TDP-43 proteinopathy caused by a novel deletion in progranulin gene (PGRN). | Q41259318 | ||
| Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase. | Q41933726 | ||
| Extracellular progranulin protects cortical neurons from toxic insults by activating survival signaling | Q42059392 | ||
| Progranulin deficiency leads to enhanced cell vulnerability and TDP-43 translocation in primary neuronal cultures | Q42871327 | ||
| Estimating the age of the most common Italian GRN mutation: walking back to Canossa times | Q43442435 | ||
| Increased caspase activation and decreased TDP-43 solubility in progranulin knockout cortical cultures | Q43861982 | ||
| Microglial upregulation of progranulin as a marker of motor neuron degeneration | Q45809407 | ||
| Serum biomarker for progranulin-associated frontotemporal lobar degeneration | Q46087404 | ||
| Variability of the clinical phenotype in an Italian family with dementia associated with an intronic deletion in the GRN gene. | Q46302059 | ||
| Genetic variability in progranulin contributes to risk for clinically diagnosed Alzheimer disease | Q46813677 | ||
| Corticobasal syndrome associated with the A9D Progranulin mutation | Q46965357 | ||
| A novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology | Q48199458 | ||
| Mutations other than null mutations producing a pathogenic loss of progranulin in frontotemporal dementia | Q48250357 | ||
| Progranulin plasma levels as potential biomarker for the identification of GRN deletion carriers. A case with atypical onset as clinical amnestic Mild Cognitive Impairment converted to Alzheimer's disease | Q48484561 | ||
| Frequency of progranulin mutations in a German cohort of 79 frontotemporal dementia patients | Q48515203 | ||
| Clinical, neuropathological, and genetic characteristics of the novel IVS9+1delG GRN mutation in a patient with frontotemporal dementia | Q48640322 | ||
| A Belgian ancestral haplotype harbours a highly prevalent mutation for 17q21-linked tau-negative FTLD. | Q48640333 | ||
| P433 | issue | 2 | |
| P921 | main subject | biomarker | Q864574 |
| neurodegeneration | Q1755122 | ||
| P304 | page(s) | 180-190 | |
| P577 | publication date | 2012-08-02 | |
| P1433 | published in | American journal of neurodegenerative disease | Q27724305 |
| P1476 | title | Circulating progranulin as a biomarker for neurodegenerative diseases | |
| P478 | volume | 1 |
| Q90248276 | A review on shared clinical and molecular mechanisms between bipolar disorder and frontotemporal dementia |
| Q64891208 | CSF Biomarkers of Neurodegeneration in Progressive Non-fluent Aphasia and Other Forms of Frontotemporal Dementia: Clues for Pathomechanisms? |
| Q30828939 | Digital Detection of Exosomes by Interferometric Imaging |
| Q87674557 | Evaluation of the salivary levels of visfatin, chemerin, and progranulin in periodontal inflammation |
| Q64106726 | Microglial Progranulin: Involvement in Alzheimer's Disease and Neurodegenerative Diseases |
| Q26766487 | Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders |
| Q26782984 | Phenotypic Heterogeneity of Monogenic Frontotemporal Dementia |
| Q38667291 | Progranulin Mutations Affects Brain Oscillatory Activity in Fronto-Temporal Dementia. |
| Q36293051 | Progranulin and Its Related MicroRNAs after Status Epilepticus: Possible Mechanisms of Neuroprotection |
| Q46958756 | The Genetics of Monogenic Frontotemporal Dementia |
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