Human papillomavirus oncoprotein E6 upregulates c-Met through p53 downregulation

scientific article published on 20 July 2016

Human papillomavirus oncoprotein E6 upregulates c-Met through p53 downregulation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.EJCA.2016.06.006
P932PMC publication ID5002257
P698PubMed publication ID27451021

P50authorKelly R. MaglioccaQ89464035
P2093author name stringShi-Yong Sun
Dong M Shin
Dongsheng Wang
Zhongliang Hu
Sungjin Kim
Nabil F Saba
Zhengjia Chen
Guoqing Qian
Zhuo G Chen
Sreenivas Nannapaneni
P2860cites workHuman Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United StatesQ22306233
Targeting the hepatocyte growth factor-cMET axis in cancer therapyQ24606259
Optimization of biotinyl-tyramide-based in situ hybridization for sensitive background-free applications on formalin-fixed, paraffin-embedded tissue specimensQ24800680
Human papillomavirus and survival of patients with oropharyngeal cancer.Q27851567
Targeting the c-Met signaling pathway in cancerQ28246393
HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytesQ28254780
Comprehensive genomic characterization of head and neck squamous cell carcinomasQ28256121
Case-control study of human papillomavirus and oropharyngeal cancerQ28301695
The mutational landscape of head and neck squamous cell carcinomaQ29614654
Novel insight into mutational landscape of head and neck squamous cell carcinomaQ30441193
The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinomaQ30494514
Combination of anti-HER3 antibody MM-121/SAR256212 and cetuximab inhibits tumor growth in preclinical models of head and neck squamous cell carcinomaQ33875560
Alteration of microRNA profiles in squamous cell carcinoma of the head and neck cell lines by human papillomavirusQ34127590
siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cellsQ34227843
The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neckQ34639763
Human papillomavirus 16 oncoprotein regulates the translocation of β-catenin via the activation of epidermal growth factor receptorQ34944436
Growth factor receptor expression in anal squamous lesions: modifications associated with oncogenic human papillomavirus and human immunodeficiency virusQ35000164
Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomasQ35008028
Wild-type p53 controls cell motility and invasion by dual regulation of MET expressionQ35180856
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.Q35589619
Mechanisms of human papillomavirus-induced oncogenesis.Q35915935
Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemiaQ36223356
Molecular biology of human papillomavirus infection and cervical cancerQ36441612
miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartmentQ37706146
Human papillomavirus oncoproteins: pathways to transformationQ37769103
MET: a promising anticancer therapeutic targetQ38008247
The Met receptor tyrosine kinase: a key player in oncogenesis and drug resistanceQ38175267
Biological, diagnostic and therapeutic relevance of the MET receptor signaling in head and neck cancer.Q38208571
C-Met pathway promotes self-renewal and tumorigenecity of head and neck squamous cell carcinoma stem-like cellQ38212355
De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma: a systematic review and meta-analysis of current clinical trials.Q38236897
c-Met expression is a marker of poor prognosis in patients with locally advanced head and neck squamous cell carcinoma treated with chemoradiation.Q38392890
Human Papillomavirus-Associated Oropharyngeal Cancer: Defining Risk Groups and Clinical TrialsQ38583292
Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancerQ39044577
Head neck squamous cell carcinoma c-Met⁺ cells display cancer stem cell properties and are responsible for cisplatin-resistance and metastasisQ39608945
Therapeutic potential of recombinant p53 overexpression in breast cancer cells expressing endogenous wild-type p53.Q41040883
A recombinant adenovirus expressing wild type p53 induces apoptosis in drug-resistant human breast cancer cells: a gene therapy approach for drug-resistant cancers.Q41074771
Frequent hepatocyte growth factor overexpression and low frequency of c-Met gene amplification in human papillomavirus-negative tonsillar squamous cell carcinoma and their prognostic significancesQ42219837
Hepatocyte growth factor and c-Met in cervical intraepithelial neoplasia: overexpression of proteins associated with oncogenic human papillomavirus and human immunodeficiency virusQ45729463
Comparison of in-situ hybridization, direct and indirect in-situ PCR as well as tyramide signal amplification for the detection of HPV.Q50519722
Cancer of the head and neck is the sixth most common cancer worldwideQ83102756
P4510describes a project that usesImageJQ1659584
P304page(s)21-32
P577publication date2016-07-20
P1433published inEuropean Journal of CancerQ332260
P1476titleHuman papillomavirus oncoprotein E6 upregulates c-Met through p53 downregulation
P478volume65

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cites work (P2860)
Q47616848Clinical and prognostic value of the C-Met/HGF signaling pathway in cervical cancer
Q49414583Clinicopathological impacts of high c-Met expression in head and neck squamous cell carcinoma: a meta-analysis and review
Q33607965Hepatocyte Growth Factor/c-Met Signaling in Head and Neck Cancer and Implications for Treatment
Q89865978MiR-23b-3p reduces the proliferation, migration and invasion of cervical cancer cell lines via the reduction of c-Met expression
Q55717696Prognostic role of c-Met in head and neck squamous cell cancer tissues: a meta-analysis.
Q40444191The Interaction Between Human Papillomaviruses and the Stromal Microenvironment