Nedd4L modulates the transcription of metalloproteinase-1 and -13 genes to increase the invasive activity of gallbladder cancer

scientific article published on October 5, 2010

Nedd4L modulates the transcription of metalloproteinase-1 and -13 genes to increase the invasive activity of gallbladder cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1365-2613.2010.00740.X
P953full work available at URLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081510
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21039987/?tool=EBI
P932PMC publication ID3081510
P698PubMed publication ID21039987
P5875ResearchGate publication ID47643301

P2093author name stringMutsuo Furihata
Tamotsu Takeuchi
Yoshihiro Adachi
Tomoko Nagayama
P2860cites workExpression of T-cadherin (CDH13, H-Cadherin) in human brain and its characteristics as a negative growth regulator of epidermal growth factor in neuroblastoma cellsQ22253393
Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptorsQ24316214
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applicationsQ24561689
WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndromeQ24563029
Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functionsQ24651528
Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approachQ24653749
Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factorsQ24806147
A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channelQ28512481
Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arraysQ28566104
Regulation of matrix metalloproteinase expression in tumor invasion.Q33605726
Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channelQ34100646
A ubiquitin ligase, skeletrophin, is a negative regulator of melanoma invasionQ34528954
The Nedd4-like family of E3 ubiquitin ligases and cancerQ34668206
p38delta/MAPK13 as a diagnostic marker for cholangiocarcinoma and its involvement in cell motility and invasionQ35007282
Collagenases in cancerQ36076488
Expression of MMP-2,TIMP-2 protein and the ratio of MMP-2/TIMP-2 in gallbladder carcinoma and their significanceQ36308445
Chronic inflammation: a common and important factor in the pathogenesis of neoplasiaQ36412290
Clinical importance of p53 protein in gall bladder carcinoma and its precursor lesionsQ37250734
T-cadherin modulates tumor-associated molecules in gallbladder cancer cellsQ39745464
Oncolytic adenoviral therapy in gallbladder carcinomaQ40430315
NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptorQ40501781
Relative contribution of Nedd4 and Nedd4-2 to ENaC regulation in epithelia determined by RNA interferenceQ40612889
A MEK inhibitor (U0126) prolongs survival in nude mice bearing human gallbladder cancer cells with K-ras mutation: analysis in a novel orthotopic inoculation modelQ40636256
Mutations of p16Ink4/CDKN2 and p15Ink4B/MTS2 genes in biliary tract cancers.Q41328380
Epidemiologic aspects of gallbladder cancer: a case-control study of the SEARCH Program of the International Agency for Research on CancerQ50155198
Prediction of prognosis in gallbladder carcinoma by CD147 and MMP-2 immunohistochemistryQ50157232
Gallbladder cancerQ57646726
Ki-ras mutations as a prognostic factor in extrahepatic bile system cancer. PANK-ras I Project InvestigatorsQ71848697
p53 protein immunoreactivity in extrahepatic bile duct and gallbladder cancer: Correlation with tumor grade and survivalQ72016095
Mutation of the p53 gene in gallbladder cancerQ72157099
Zeb1-mediated T-cadherin repression increases the invasive potential of gallbladder cancerQ83129751
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectneoplastic gene expression regulationQ66660300
P304page(s)79-86
P577publication date2010-10-05
P1433published inInternational Journal of Experimental PathologyQ15750807
P1476titleNedd4L modulates the transcription of metalloproteinase-1 and -13 genes to increase the invasive activity of gallbladder cancer
P478volume92

Reverse relations

cites work (P2860)
Q36299135DDB2 modulates TGF-β signal transduction in human ovarian cancer cells by downregulating NEDD4L.
Q84935997Decreased expression of Nedd4L correlates with poor prognosis in gastric cancer patient
Q43539447Down-regulation of Nedd4L is associated with the aggressive progression and worse prognosis of malignant glioma
Q94938995Downregulation of MicroRNA-494 inhibits the TGF-β1/Smads signaling pathway and prevents the development of hypospadias through upregulating Nedd4L
Q28391482Genome-wide analysis in human colorectal cancer cells reveals ischemia-mediated expression of motility genes via DNA hypomethylation
Q34787147Identification of the NEDD4L gene as a prognostic marker by integrated microarray analysis of copy number and gene expression profiling in non-small cell lung cancer
Q39503945Matrix metalloproteinase-11 overexpressed in lobular carcinoma cells of the breast promotes anoikis resistance
Q38272580NEDD4-2 (NEDD4L): the ubiquitin ligase for multiple membrane proteins
Q35060566NEDD4L is downregulated in colorectal cancer and inhibits canonical WNT signaling
Q38886538Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity.
Q38383636Nedd4L expression is decreased in ovarian epithelial cancer tissues compared to ovarian non-cancer tissue
Q89586028Neural precursor cell-expressed developmentally down-regulated 4-like: a new biomarker in the pathophysiology of endometrial cancer
Q39031391Pathobiological properties of the ubiquitin ligase Nedd4L in melanoma
Q85233117Role of altered expression of Nedd4L in the pathogenesis of systemic malignancies

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