| scholarly article | Q13442814 |
| P50 | author | Manuela Baccarini | Q21264306 |
| Erwin F. Wagner | Q40012298 | ||
| Mario Mikula | Q42797307 | ||
| Rotraud Wieser | Q57070700 | ||
| Martin Schreiber | Q57514972 | ||
| P2093 | author name string | Beug H | |
| Zatloukal K | |||
| Kucerova L | |||
| Rüth J | |||
| Husak Z | |||
| P2860 | cites work | Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation | Q22011170 |
| Endothelial apoptosis in Braf-deficient mice | Q24314857 | ||
| Bcl-2 targets the protein kinase Raf-1 to mitochondria | Q24321753 | ||
| Ras-related proteins in signal transduction and growth control | Q24324056 | ||
| Isoform-specific localization of A-RAF in mitochondria | Q24553134 | ||
| Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines | Q24683034 | ||
| Detection of specific sequences among DNA fragments separated by gel electrophoresis | Q25939003 | ||
| Localization of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 pool | Q28139493 | ||
| Biochemical analysis of MEK activation in NIH3T3 fibroblasts. Identification of B-Raf and other activators | Q28299416 | ||
| The complexity of Raf-1 regulation | Q28305850 | ||
| MEK kinase activity is not necessary for Raf-1 function | Q28362229 | ||
| NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses | Q28505819 | ||
| Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells | Q28609131 | ||
| Purification of a Ras-dependent mitogen-activated protein kinase kinase kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins | Q28609134 | ||
| Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases | Q28609156 | ||
| Activation of mitochondrial Raf-1 is involved in the antiapoptotic effects of Akt | Q28646056 | ||
| Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting | Q29614543 | ||
| An essential role for NF-kappaB in preventing TNF-alpha-induced cell death | Q29614707 | ||
| Mitogen-activated protein kinases: specific messages from ubiquitous messengers | Q30303652 | ||
| Partial purification of a mitogen-activated protein kinase kinase activator from bovine brain. Identification as B-Raf or a B-Raf-associated activity. | Q30465793 | ||
| NF-kappaB to the rescue: RELs, apoptosis and cellular transformation | Q33650519 | ||
| Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis | Q33959860 | ||
| The murine N-ras gene is not essential for growth and development | Q34650223 | ||
| K-ras is an essential gene in the mouse with partial functional overlap with N-ras | Q35192456 | ||
| Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation | Q35688302 | ||
| Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant | Q36401150 | ||
| RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter | Q36553588 | ||
| Abrogation of c-Raf expression induces apoptosis in tumor cells. | Q38337664 | ||
| The effect of c-raf antisense oligonucleotides on growth factor-induced proliferation of hematopoietic cells | Q40961206 | ||
| Interactions between Ras and Raf: key regulatory proteins in cellular transformation | Q40974378 | ||
| Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry | Q40976467 | ||
| Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. | Q41128352 | ||
| The role of Raf kinases in development and growth of tumors | Q41205831 | ||
| Apoptosis regulation by interaction of Bcl-2 protein and Raf-1 kinase. | Q41444236 | ||
| Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility | Q41670118 | ||
| Probing structure and function of the raf protein kinase domain with monoclonal antibodies | Q41736544 | ||
| High molecular weight component of Mallory bodies detected by a monoclonal antibody | Q43484254 | ||
| Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene. | Q45971337 | ||
| The Raf-1 protein mediates insulin-like growth factor-induced proliferation of erythroid progenitor cells | Q48001351 | ||
| Craf-1 protein kinase is essential for mouse development. | Q51990813 | ||
| Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death. | Q52523359 | ||
| c-Jun is essential for normal mouse development and hepatogenesis | Q57083732 | ||
| [29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf | Q58438199 | ||
| BAD Enables Ceramide to Signal Apoptosis via Ras and Raf-1 | Q59123101 | ||
| Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase | Q77195536 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | apoptotic process | Q14599311 |
| P304 | page(s) | 1952-1962 | |
| P577 | publication date | 2001-04-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene | |
| P478 | volume | 20 |
| Q38220879 | "RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway |
| Q39738214 | A MAPK pathway mediates ethylene signaling in plants |
| Q35600821 | A MEK-independent role for CRAF in mitosis and tumor progression. |
| Q43543397 | A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal |
| Q91923527 | A Premature Stop Codon in RAF1 Is the Priority Candidate Causative Mutation of the Inherited Chicken Wingless-2 Developmental Syndrome |
| Q39732365 | A Raf-1 mutant that dissociates MEK/extracellular signal-regulated kinase activation from malignant transformation and differentiation but not proliferation. |
| Q28818626 | A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis |
| Q36421146 | A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes |
| Q40666435 | Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways |
| Q39102460 | Allosteric activation of functionally asymmetric RAF kinase dimers |
| Q33297829 | Altered trophoblast proliferation is insufficient to account for placental dysfunction in Egfr null embryos |
| Q34728330 | An old kinase on a new path: Raf and apoptosis |
| Q35710217 | Angiogenic sprouting requires the fine tuning of endothelial cell cohesion by the Raf-1/Rok-α complex |
| Q40464878 | Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1. |
| Q40543086 | B-RAF is a therapeutic target in melanoma |
| Q30443185 | B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organization |
| Q28508452 | B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts |
| Q28235023 | B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms |
| Q53321121 | B-Raf is required for ERK activation and tumor progression in a mouse model of pancreatic beta-cell carcinogenesis. |
| Q28507477 | B-Raf-mediated signaling pathway regulates T cell development |
| Q30664961 | C-Raf deficiency leads to hearing loss and increased noise susceptibility |
| Q37389958 | C-Raf is associated with disease progression and cell proliferation in a subset of melanomas |
| Q34413075 | CNK1 is a scaffold protein that regulates Src-mediated Raf-1 activation |
| Q41825679 | CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation |
| Q40051060 | Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis |
| Q37505664 | Cell and molecular biology of the novel protein tyrosine-phosphatase-interacting protein 51. |
| Q34301824 | Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38 |
| Q39942488 | Characterization of Ser338 phosphorylation for Raf-1 activation |
| Q33740213 | Characterization of the B-Raf interactome in mouse hippocampal neuronal cells |
| Q35634546 | Conferring specificity on the ubiquitous Raf/MEK signalling pathway |
| Q29618995 | Coordinating ERK/MAPK signalling through scaffolds and inhibitors |
| Q28513466 | Cortical migration defects in mice expressing A-RAF from the B-RAF locus |
| Q39633245 | Crosstalk between autophagy and apoptosis in the regulation of paclitaxel-induced cell death in v-Ha-ras-transformed fibroblasts |
| Q28205761 | Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation |
| Q39674723 | Cyclic AMP blocks cell growth through Raf-1-dependent and Raf-1-independent mechanisms |
| Q33730583 | DA-Raf-dependent inhibition of the Ras-ERK signaling pathway in type 2 alveolar epithelial cells controls alveolar formation |
| Q34522855 | Deadly encounter: ubiquitin meets apoptosis |
| Q40760852 | Dephosphorylation of Ser-259 regulates Raf-1 membrane association |
| Q44997546 | Differential regulation of mesangial cell mitogenesis by cAMP phosphodiesterase isozymes 3 and 4. |
| Q34440570 | Disorders of dysregulated signal traffic through the RAS-MAPK pathway: phenotypic spectrum and molecular mechanisms |
| Q28365569 | Drosophila-raf acts to elaborate dorsoventral pattern in the ectoderm of developing embryos |
| Q81236740 | ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf |
| Q35744552 | ERK signaling, but not c-Raf, is required for gonadotropin-releasing hormone (GnRH)-induced regulation of Nur77 in pituitary gonadotropes |
| Q40753319 | ERK signalling and oncogene transformation are not impaired in cells lacking A-Raf |
| Q33196491 | Engineering the serine/threonine protein kinase Raf-1 to utilise an orthogonal analogue of ATP substituted at the N6 position |
| Q34334827 | Essential role of B-Raf in ERK activation during extraembryonic development |
| Q36491749 | Essential role of B-Raf in oligodendrocyte maturation and myelination during postnatal central nervous system development |
| Q41785401 | Formation of endothelial lumens requires a coordinated PKCepsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation |
| Q41909915 | From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-alpha kinase activity |
| Q28595029 | Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival. |
| Q41908055 | Genetics of papillary thyroid cancer initiation: implications for therapy |
| Q40126556 | Grb10 and active Raf-1 kinase promote Bad-dependent cell survival |
| Q36376016 | Histology atlas of the developing mouse hepatobiliary system with emphasis on embryonic days 9.5-18.5. |
| Q40637880 | Identification of residues and domains of Raf important for function in vivo and in vitro |
| Q35574674 | Identification of signalling cascades involved in red blood cell shrinkage and vesiculation |
| Q40582602 | Immortalized p19ARF null hepatocytes restore liver injury and generate hepatic progenitors after transplantation. |
| Q52625679 | Impaired neuronal maturation of hippocampal neural progenitor cells in mice lacking CRAF. |
| Q36706331 | In vivo functions of mitogen-activated protein kinases: conclusions from knock-in and knock-out mice |
| Q39665762 | Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling |
| Q34512913 | Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. |
| Q35648144 | Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice |
| Q36094669 | MAP kinase pathways: the first twenty years |
| Q34853182 | MAP3Ks as central regulators of cell fate during development |
| Q64059604 | MAPK/ERK Signaling in Regulation of Renal Differentiation |
| Q46514063 | MEK hyperphosphorylation coincides with cell cycle shut down of cultured smooth muscle cells |
| Q28362229 | MEK kinase activity is not necessary for Raf-1 function |
| Q30441421 | MEK1 activation by PAK: a novel mechanism |
| Q34030536 | MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma |
| Q36745371 | MKK signaling and vascularization. |
| Q41811052 | MOZ-mediated repression of p16(INK) (4) (a) is critical for the self-renewal of neural and hematopoietic stem cells |
| Q37067007 | Macrophage differentiation increases expression of the ascorbate transporter (SVCT2) |
| Q33832649 | Mammalian Ste20-like kinase (Mst2) indirectly supports Raf-1/ERK pathway activity via maintenance of protein phosphatase-2A catalytic subunit levels and consequent suppression of inhibitory Raf-1 phosphorylation |
| Q28183716 | Mechanisms of regulating the Raf kinase family |
| Q37785803 | Mechanistic principles of RAF kinase signaling |
| Q28648056 | Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein. |
| Q36787582 | Molecular mechanism of liver development and regeneration |
| Q43005729 | Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma |
| Q73738461 | Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice |
| Q33806161 | Noonan syndrome: clinical aspects and molecular pathogenesis |
| Q35557587 | Nuclear factor-kappa B plays a central role in tumour necrosis factor-mediated liver disease. |
| Q37938862 | Opioid receptor trafficking and signaling: what happens after opioid receptor activation? |
| Q28586031 | Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription |
| Q24291785 | Phylogenetic conservation of the makorin-2 gene, encoding a multiple zinc-finger protein, antisense to the RAF1 proto-oncogene |
| Q28513384 | Placental alpha(2)-adrenoceptors control vascular development at the interface between mother and embryo |
| Q34281240 | Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output. |
| Q36371333 | Protein kinases of the Hippo pathway: regulation and substrates |
| Q45317145 | RAF activation |
| Q30477716 | RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development |
| Q50782705 | REST and its downstream molecule Mek5 regulate survival of primordial germ cells. |
| Q36755945 | RKIP regulates MAP kinase signaling in cells with defective B-Raf activity |
| Q33193874 | Raf and the road to cell survival: a tale of bad spells, ring bearers and detours |
| Q24316181 | Raf family kinases: old dogs have learned new tricks |
| Q36002845 | Raf kinases: function, regulation and role in human cancer |
| Q37094120 | Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaB |
| Q42944944 | Raf-1 antagonizes erythroid differentiation by restraining caspase activation |
| Q33357285 | Raf-1 is not required for megakaryocytopoiesis or TPO-induced ERK phosphorylation |
| Q41887999 | Raf-1 regulates Rho signaling and cell migration |
| Q28504557 | Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling |
| Q45345638 | Raf-1 without MEK? |
| Q27692653 | Raf-interactome in tuning the complexity and diversity of Raf function |
| Q35459718 | Rafs constitute a nodal point in the regulation of embryonic endothelial progenitor cell growth and differentiation |
| Q34282328 | RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis. |
| Q75197302 | Ras protects Rb family null fibroblasts from cell death: a role for AP-1 |
| Q34660771 | Ras/Raf signalling and emerging pharmacotherapeutic targets |
| Q28580581 | Regulation and role of Raf-1/B-Raf heterodimerization |
| Q35014068 | Regulation of B-cell fate by antigen-receptor signals |
| Q38439535 | Regulation of RAF protein kinases in ERK signalling |
| Q41978120 | Regulation of cellular proliferation, differentiation and cell death by activated Raf. |
| Q36755421 | Rho kinase in the regulation of cell death and survival |
| Q37822317 | Role of Ras/Raf/MEK/ERK signaling in physiological hematopoiesis and leukemia development |
| Q24304936 | Second nature: biological functions of the Raf-1 "kinase" |
| Q40802439 | Simian virus 40 large tumor antigen modulates the Raf signaling pathway |
| Q34520122 | Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors |
| Q40517852 | Src tyrosine kinase inhibitor PP2 markedly enhances Ras-independent activation of Raf-1 protein kinase by phorbol myristate acetate and H2O2. |
| Q40307509 | Stimulation of β-adrenergic receptors plays a protective role via increased expression of RAF-1 and PDX-1 in hyperglycemic rat pancreatic islet (RIN-m5F) cells |
| Q34472774 | TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling |
| Q36944803 | TNFR1 promotes tumor necrosis factor-mediated mouse colon epithelial cell survival through RAF activation of NF-kappaB. |
| Q92663940 | Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy |
| Q24670427 | The B lymphocyte adaptor molecule of 32 kD (Bam32) regulates B cell antigen receptor signaling and cell survival |
| Q29620153 | The RAF proteins take centre stage |
| Q39827200 | The enhancement of Raf-1 kinase activity by knockdown of Spry2 is associated with high sensitivity to paclitaxel in v-Ha-ras-transformed NIH 3T3 fibroblasts |
| Q51869777 | The expression of Akt and ERK1/2 proteins decreased in dexamethasone-induced intrauterine growth restricted rat placental development. |
| Q24794871 | The functional genomic response of developing embryonic submandibular glands to NF-kappa B inhibition |
| Q37201867 | The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors. |
| Q51328396 | The lack of Raf-1 kinase feedback regulation enhances antiapoptosis in cancer cells. |
| Q27334753 | The phosphate transporter PiT1 (Slc20a1) revealed as a new essential gene for mouse liver development |
| Q40626766 | The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis. |
| Q39077751 | The secret life of kinases: functions beyond catalysis |
| Q35919391 | The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component |
| Q34275807 | The tumor suppressor DiRas3 forms a complex with H-Ras and C-RAF proteins and regulates localization, dimerization, and kinase activity of C-RAF |
| Q35577420 | Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis |
| Q34338213 | To be or not to be: a question of B-Raf? |
| Q64109800 | Understanding the marvels behind liver regeneration |
| Q36497720 | c-Raf promotes angiogenesis during normal growth plate maturation |
| Q39554370 | c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma |
| Q21134956 | p21-Activated kinase 1 (Pak1) phosphorylates BAD directly at serine 111 in vitro and indirectly through Raf-1 at serine 112 |
Search more.