Polymorphisms in Promoter Sequences of the p15 INK4B and PTEN Genes of Normal Japanese Individuals

scientific article published on September 23, 2010

Polymorphisms in Promoter Sequences of the p15 INK4B and PTEN Genes of Normal Japanese Individuals is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S10528-010-9379-3
P953full work available at URLhttp://link.springer.com/article/10.1007/s10528-010-9379-3/fulltext.html
http://link.springer.com/content/pdf/10.1007/s10528-010-9379-3
http://link.springer.com/content/pdf/10.1007/s10528-010-9379-3.pdf
P698PubMed publication ID20862607

P2093author name stringToshiyuki Sakai
Hoyoku Nishino
Yasuhito Ohsaka
Shingo Yogosawa
Ryoko Nakanishi
P2860cites workHaematologicaQ5638209
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrestQ24319021
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
Germline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathwayQ24532136
PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerasesQ24548129
Comprehensive genomic characterization defines human glioblastoma genes and core pathwaysQ24656128
A haplotype map of the human genomeQ24679827
Heart and vessels. SupplementQ27711384
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell linesQ28138728
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancersQ28306997
Regulation of PTEN transcription by p53Q28646911
TRANSFAC: an integrated system for gene expression regulationQ29614502
A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation.Q30375206
The essence of SNPsQ33681170
NBP is the p53 homolog p63.Q33933708
p53CP is p51/p63, the third member of the p53 gene family: partial purification and characterizationQ33933714
Characterization of DNA polymerase from Pyrococcus sp. strain KOD1 and its application to PCRQ34065451
Clinical and genetic characteristics of Japanese Burkitt lymphomas with or without leukemic presentationQ34535101
p53 and p73 display common and distinct requirements for sequence specific binding to DNAQ35646680
Methyl-CpG binding proteins in the nervous systemQ36109301
A temperature-sensitive mutant of human p53.Q37632919
Transforming Growth Factor β Activates the Promoter of Cyclin-dependent Kinase Inhibitor p15 through an Sp1 Consensus SiteQ38289403
TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4bQ39420254
Regulation of the PTEN promoter by statins and SREBP.Q40038228
CBF-1 (RBP-J kappa) binds to the PTEN promoter and regulates PTEN gene expressionQ40179833
Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-betaQ40370863
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humansQ40490424
Association of the polymorphisms in the 5′‐untranslated region of PTEN gene with type 2 diabetes in a Japanese populationQ40615998
The Egr-1 transcription factor directly activates PTEN during irradiation-induced signallingQ43848062
p15INK4b in HDAC inhibitor‐induced growth arrestQ44658996
Genetic and epigenetic alterations of the PTEN gene in soft tissue sarcomasQ46488674
No association between the MDM2 -309 T/G promoter polymorphism and breast cancer in African-Americans or WhitesQ46621561
p53-dependent induction of WAF1 by cold shock in human glioblastoma cellsQ48496899
A mutation in the beta 3-adrenergic receptor gene is associated with obesity and hyperinsulinemia in Japanese subjects.Q51585103
The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma.Q53353365
DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia.Q54557696
Allelic frequency of p53 gene codon 72 polymorphism in urologic cancers.Q55363371
Mutations in the p53 tumor suppressor gene in colorectal cancer in TaiwanQ73499341
Association of a T29-->C polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to myocardial infarction in JapaneseQ73907419
Promoter analysis of tumor suppressor gene PTEN: identification of minimum promoter regionQ77798898
MDM2 promoter SNP309 is associated with the risk of hepatocellular carcinoma in patients with chronic hepatitis CQ80129017
Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancerQ80635954
Promoter methylation of P15(INK4B) gene is possibly associated with parvovirus B19 infection in adult acute leukemiasQ81003918
P433issue11-12
P407language of work or nameEnglishQ1860
P921main subjectpromoterQ224093
regulation of gene expressionQ411391
genetic polymorphismQ3395645
P304page(s)970-986
P577publication date2010-09-23
P1433published inBiochemical GeneticsQ15765855
P1476titlePolymorphisms in promoter sequences of the p15 ( INK4B ) and PTEN genes of normal Japanese individuals
Polymorphisms in Promoter Sequences of the p15 INK4B and PTEN Genes of Normal Japanese Individuals
P478volume48