PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation.

scientific article published on February 1999

PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/27.3.866
P932PMC publication ID148259
P698PubMed publication ID9889285
P5875ResearchGate publication ID13400386

P50authorMichael TainskyQ67482970
P2093author name stringY Yu
P Kannan
S Wankhade
P2860cites workAn alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2Q24308857
Interaction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factorQ24313335
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cellsQ27860607
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
A new technique for the assay of infectivity of human adenovirus 5 DNAQ27860797
Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteinsQ28266897
Poly(ADP-ribose) binds to specific domains of p53 and alters its DNA binding functionsQ28269174
Analysis of the DNA-binding and activation properties of the human transcription factor AP-2Q28271397
Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1Q28282333
Inhibition of HIV-1 IIIb replication in AA-2 and MT-2 cells in culture by two ligands of poly (ADP-ribose) polymerase: 6-amino-1,2-benzopyrone and 5-iodo-6-amino-1,2-benzopyroneQ28333970
cDNA sequence, protein structure, and chromosomal location of the human gene for poly(ADP-ribose) polymeraseQ30403143
Regulation of the expression or recruitment of components of the DNA synthesome by poly(ADP-ribose) polymeraseQ32058647
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.Q33887607
Coactivator PC4 mediates AP-2 transcriptional activity and suppresses ras-induced transformation dependent on AP-2 transcriptional interferenceQ33957311
Prevention of tumorigenesis of oncogene-transformed rat fibroblasts with DNA site inhibitors of poly(ADP ribose) polymeraseQ34598085
The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinomaQ34725896
Loss of amplified genes by poly(ADP-ribose) polymerase inhibitorsQ35034213
Advances in RNA polymerase II transcriptionQ35673499
Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitroQ36035454
Genetic studies of the lac repressor. X. Analysis of missense mutations in the lacI geneQ39689363
Transcriptional regulation by extracellular signals: mechanisms and specificityQ40579098
Structure and function of poly(ADP-ribose) polymeraseQ40616439
Poly(ADP-ribose) polymerase: a molecular nick-sensorQ40664349
Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaksQ40930035
Multiple steps in the regulation of transcription-factor level and activityQ41036772
Transcriptional interference caused by GCN4 overexpression reveals multiple interactions mediating transcriptional activationQ41674567
Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell deathQ41717170
Susceptibility for N-ras-mediated transformation requires loss of tumor suppressor activityQ41748545
Adenovirus type 12 early region 1A expresses a 52R protein repressing the trans-activating activity of transcription factor c-Jun/AP-1.Q42504582
Characterization of a human ovarian teratocarcinoma-derived cell lineQ42799877
Identification of domains of poly(ADP-ribose) polymerase for protein binding and self-associationQ42829897
Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5' element and c-fos 3' sequencesQ48375058
Interaction of the transcription factor YY1 with human poly(ADP-ribosyl) transferase.Q52998091
N-ras oncogene causes AP-2 transcriptional self-interference, which leads to transformation.Q53472029
Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region.Q54739833
Negative effect of the transcriptional activator GAL4Q59072863
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)866-874
P577publication date1999-02-01
P1433published inNucleic Acids ResearchQ135122
P1476titlePolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation
P478volume27

Reverse relations

cites work (P2860)
Q356835743. Life or death decisions: the cast of poly(ADP-ribose)polymerase (PARP) as a therapeutic target for brain ischaemia.
Q34269353A cellular survival switch: poly(ADP-ribosyl)ation stimulates DNA repair and silences transcription
Q61906687AP-2 transcription factors in the regulation of ERBB2 gene transcription by oestrogen
Q46683907AP-2β is a transcriptional regulator for determination of digit length in tetrapods.
Q34520738Absence of poly(ADP-ribose)polymerase-1 alters nuclear factor-kappa B activation and gene expression of apoptosis regulators after reperfusion injury
Q43871211Activation of poly(ADP-Ribose) polymerase-1 is a central mechanism of lipopolysaccharide-induced acute lung inflammation
Q24648448Activator protein 2alpha associates with adenomatous polyposis coli/beta-catenin and Inhibits beta-catenin/T-cell factor transcriptional activity in colorectal cancer cells
Q36748207Activator protein-2 in carcinogenesis with a special reference to breast cancer--a mini review
Q24530625Activator protein-2gamma (AP-2gamma) expression is specifically induced by oestrogens through binding of the oestrogen receptor to a canonical element within the 5'-untranslated region
Q37346306Beyond DNA Repair: Additional Functions of PARP-1 in Cancer
Q38346928Differential regulation of activator protein-1 and heat shock factor-1 in myocardial ischemia and reperfusion injury: role of poly(ADP-ribose) polymerase-1.
Q74088951Dominant-negative transcription factor AP-2 augments SB-2 melanoma tumor growth in vivo
Q40550641Dual regulation of AP-2alpha transcriptional activation by poly(ADP-ribose) polymerase-1
Q33525589Enhanced binding of poly(ADP-ribose)polymerase-1 and Ku80/70 to the ITGA2 promoter via an extended cytosine-adenosine repeat
Q39832779Function of retinoid acid receptor alpha and p21 in all-trans-retinoic acid-induced acute T-lymphoblastic leukemia apoptosis
Q39388383Functional characterization of the interacting domains of the positive coactivator PC4 with the transcription factor AP-2alpha.
Q40835336Functional competition between poly(ADP-ribose) polymerase and its 24-kDa apoptotic fragment in DNA repair and transcription
Q51601350Functional interaction between human papillomavirus type 18 E2 and poly(ADP-ribose) polymerase 1.
Q88626480Gene Expression in Parp1 Deficient Mice Exposed to a Median Lethal Dose of Gamma Rays
Q34500001Histone variants and histone modifications: a structural perspective
Q38269737Histone-mediated epigenetics in addiction
Q28211366Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2
Q28180608Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437
Q33595109Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genes
Q33798511Identification of poly(ADP-ribose) polymerase as a transcriptional coactivator of the human T-cell leukemia virus type 1 Tax protein
Q33267541Identification of poly(ADP-ribose)polymerase-1 and Ku70/Ku80 as transcriptional regulators of S100A9 gene expression
Q46217674In vivo regulation of the chicken cardiac troponin T gene promoter in zebrafish embryos.
Q34570024Inhibition of poly(ADP-ribose) polymerase activity is insufficient to induce tetraploidy
Q42161912Inhibitors of poly(ADP-ribose) polymerase-1 suppress transcriptional activation in lymphocytes and ameliorate autoimmune encephalomyelitis in rats
Q39942925Integrin-linked kinase regulates E-cadherin expression through PARP-1.
Q53398621Involvement of poly(ADP-ribose) polymerase in trophoblastic cell differentiation during tumorigenesis.
Q38263972Involvement of protein kinase Cdelta/extracellular signal-regulated kinase/poly(ADP-ribose) polymerase-1 (PARP-1) signaling pathway in histamine-induced up-regulation of histamine H1 receptor gene expression in HeLa cells
Q33627164Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines
Q33272645Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells
Q35271750Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase
Q40881151Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus
Q49167902N-terminal domains of plant poly(ADP-ribose) polymerases define their association with mitotic chromosomes.
Q34725803Nitric oxide-peroxynitrite-poly(ADP-ribose) polymerase pathway in the skin
Q40758269PARP co-activates B-MYB through enhanced phosphorylation at cyclin/cdk2 sites
Q28182341PARP-1, a determinant of cell survival in response to DNA damage
Q42107975PARP-1: Friend or Foe of DNA Damage and Repair in Tumorigenesis?
Q34491906PARP-2 interacts with TTF-1 and regulates expression of surfactant protein-B.
Q39232735PMA-induced dissociation of Ku86 from the promoter causes transcriptional up-regulation of histamine H(1) receptor
Q40172406Poly(ADP-Ribose) Polymerase 1 and Ste20-Like Kinase hKFC Act as Transcriptional Repressors for Gamma-2 Herpesvirus Lytic Replication
Q90645966Poly(ADP-Ribose) Polymerases in Host-Pathogen Interactions, Inflammation, and Immunity
Q35192798Poly(ADP-ribose) polymerase 1-sirtuin 1 functional interplay regulates LPS-mediated high mobility group box 1 secretion
Q28140372Poly(ADP-ribose) polymerase is a B-MYB coactivator
Q38320471Poly(ADP-ribose) polymerase upregulates E2F-1 promoter activity and DNA pol alpha expression during early S phase
Q34017468Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia
Q38528530Poly(ADP-ribose) polymerase-1 enhances transcription of the profibrotic CCN2 gene
Q34487125Poly(ADP-ribose) polymerase: a guardian angel protecting the genome and suppressing tumorigenesis
Q30824534Poly(ADP-ribose) polymerase: killer or conspirator? The 'suicide hypothesis' revisited
Q37119975Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission
Q34779828Poly(ADP-ribosyl)ation of p53 in vitro and in vivo modulates binding to its DNA consensus sequence
Q29617672Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
Q38692308Poly(adenosine diphosphate-ribose) polymerase as therapeutic target: lessons learned from its inhibitors
Q35570762Regulation of Chromatin Structure and Gene Activity by Poly(ADP-Ribose) Polymerases
Q33938665Regulation of alpha-synuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene
Q33303916Regulation of poly(ADP-ribose) polymerase-1 (PARP-1) gene expression through the post-translational modification of Sp1: a nuclear target protein of PARP-1
Q38191981Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.
Q43657060Role of poly(ADP-ribose) synthetase activation in the development of experimental allergic encephalomyelitis
Q37668700Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development
Q34638102Small interfering RNA mediated Poly (ADP-ribose) Polymerase-1 inhibition upregulates the heat shock response in a murine fibroblast cell line
Q34460815Sp1 and AP2 regulate but do not constitute TATA-less human TAF(II)55 core promoter activity
Q36672819Syncytiotrophoblastic giant cells in teratocarcinoma-like tumors derived from Parp-disrupted mouse embryonic stem cells.
Q21184171The AP-2 family of transcription factors
Q36643048The combined immunodetection of AP-2alpha and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors
Q28190711The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function
Q42434852The human transcription factor activation protein-2 gamma (AP-2gamma): gene structure, promoter, and expression in mammary carcinoma cell lines.
Q44018848The inhibition of poly(ADP-ribose) polymerase enhances growth rates of ataxia telangiectasia cells
Q90583228Therapeutic Targeting of MZF1-AS1/PARP1/E2F1 Axis Inhibits Proline Synthesis and Neuroblastoma Progression
Q24299957Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo
Q24550911Transcription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cells
Q24550724Transcriptional activation by AP-2alpha is modulated by the oncogene DEK
Q35886645Transcriptional regulation of mouse mu opioid receptor gene in neuronal cells by poly(ADP-ribose) polymerase-1.
Q40890181Transcriptional regulation of the MHC II gene DRA in untransformed human thyrocytes
Q40707585Tumorigenic effect of transcription factor hAP-2alpha and the intricate link between hAP-2alpha activation and squelching.
Q34415831Yin Yang 1 cooperates with activator protein 2 to stimulate ERBB2 gene expression in mammary cancer cells

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