Lysine methylation regulates the pRb tumour suppressor protein

scientific article

Lysine methylation regulates the pRb tumour suppressor protein is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/ONC.2009.511
P698PubMed publication ID20140018
P5875ResearchGate publication ID41414526

P2093author name stringN B La Thangue
S Carr
S Munro
A Inche
N Khaire
P2860cites workTranslating the Histone CodeQ22065840
DNA-damage-responsive acetylation of pRb regulates binding to E2F-1Q24299739
DNA-damage response control of E2F7 and E2F8Q24306816
Regulation of p53 activity through lysine methylationQ24311514
Gene-specific modulation of TAF10 function by SET9-mediated methylationQ24337399
A biomarker that identifies senescent human cells in culture and in aging skin in vivoQ24562644
Crystal structure and functional analysis of the histone methyltransferase SET7/9Q27639758
Regulation of Estrogen Receptor α by the SET7 Lysine MethyltransferaseQ27650581
The retinoblastoma protein and cell cycle controlQ27860722
Chromatin modifications and their functionQ27861067
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tailsQ28216534
Active genes are tri-methylated at K4 of histone H3Q29547668
Effects of an Rb mutation in the mouseQ29619196
Rb targets histone H3 methylation and HP1 to promotersQ29620452
The retinoblastoma gene family in differentiation and development.Q33814317
Establishment of irreversible growth arrest in myogenic differentiation requires the RB LXCXE-binding functionQ33964790
The retinoblastoma tumour suppressor in development and cancerQ34161991
SET domains and histone methylation.Q34283675
Molecular mechanisms of E2F-dependent activation and pRB-mediated repressionQ34318740
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiationQ34355279
MyoD induced cell cycle arrest is associated with increased nuclear affinity of the Rb proteinQ34438346
Cyclin A and the retinoblastoma gene product complex with a common transcription factorQ34756189
E2F and cell cycle control: a double-edged swordQ35095456
Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growthQ35187190
A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice.Q35601503
Rb is required for progression through myogenic differentiation but not maintenance of terminal differentiation.Q36321999
Heterochromatin protein 1: don't judge the book by its cover!Q36406941
Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domainQ36567545
RB and cell cycle progressionQ36579245
Conserved functions of the pRB and E2F familiesQ37249375
Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tetheringQ37474150
Acetylation regulates the differentiation-specific functions of the retinoblastoma proteinQ37544561
C-terminal truncation of the retinoblastoma gene product leads to functional inactivationQ37654636
Binding of the retinoblastoma protein is not the determinant for stable repression of some E2F-regulated promoters in muscle cellsQ40009444
Methylation of p53 by Set7/9 mediates p53 acetylation and activity in vivoQ40012428
Retinoblastoma protein switches the E2F site from positive to negative elementQ41613404
Requirement for a functional Rb-1 gene in murine developmentQ44462954
pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiationQ44652035
The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiationQ45345527
pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesisQ48852526
Binary switches and modification cassettes in histone biology and beyond.Q53854384
Acetylation control of the retinoblastoma tumour-suppressor proteinQ64379714
Down-regulation of cellular proto-oncogenes during inhibition of rat parotid acinar cell proliferationQ68181514
P433issue16
P407language of work or nameEnglishQ1860
P304page(s)2357-2367
P577publication date2010-02-08
P1433published inOncogeneQ1568657
P1476titleLysine methylation regulates the pRb tumour suppressor protein
P478volume29

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cites work (P2860)
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Q38557842Emerging roles of lysine methylation on non-histone proteins
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Q89356206Identification of Rpl29 as a major substrate of the lysine methyltransferase Set7/9
Q24310370Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein
Q36040610JMJD3 promotes SAHF formation in senescent WI38 cells by triggering an interplay between demethylation and phosphorylation of RB protein
Q38830359Lysine Methyltransferase SETD7 (SET7/9) Regulates ROS Signaling through mitochondria and NFE2L2/ARE pathway
Q38019558Lysine methylation and the regulation of p53.
Q38266428Lysine methylation in cancer: SMYD3-MAP3K2 teaches us new lessons in the Ras-ERK pathway.
Q42371486Lysine methylation of FEN1 by SET7 is essential for its cellular response to replicative stress
Q38706561Lysine methylation of promoter-bound transcription factors and relevance to cancer
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Q37970950Lysine methylation: beyond histones
Q24300912Methylation of the retinoblastoma tumor suppressor by SMYD2
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Q27003956Molecular mechanisms underlying RB protein function
Q52716935Non-canonical functions of the RB protein in cancer.
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Q38102573On your histone mark, SET, methylate!
Q41439912Opposite Effects of SET7/9 on Apoptosis of Human Acute Myeloid Leukemia Cells and Lung Cancer Cells
Q34186659PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein
Q34968529PRMT4-mediated arginine methylation negatively regulates retinoblastoma tumor suppressor protein and promotes E2F-1 dissociation
Q39112220Pleiotropic effect of somatic mutations in the E2F subunit DP-1 gene in human cancer
Q38592178Post-translational control of transcription factors: methylation ranks highly
Q38103250Posttranslational modifications of the retinoblastoma tumor suppressor protein as determinants of function
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Q26866393RB1: a prototype tumor suppressor and an enigma
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Q26853164The functional diversity of protein lysine methylation
Q27009508Transcriptional regulation by the Set7 lysine methyltransferase
Q46902580Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein

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