Splicing- and cleavage-independent requirement of RNA polymerase II CTD for mRNA release from the transcription site

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Splicing- and cleavage-independent requirement of RNA polymerase II CTD for mRNA release from the transcription site is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.200612109
P932PMC publication ID2064756
P698PubMed publication ID17938247
P5875ResearchGate publication ID5907697

P50authorMaria do Carmo FonsecaQ10326181
Noélia CustódioQ37381428
Maria VivoQ47288303
P2093author name stringMichael Antoniou
P2860cites workConditional expression of RNA polymerase II in mammalian cells. Deletion of the carboxyl-terminal domain of the large subunit affects early steps in transcription.Q54050438
Abundance of the largest subunit of RNA polymerase II in the nucleus is regulated by nucleo-cytoplasmic shuttlingQ58042336
beta-globin dominant control region interacts differently with distal and proximal promoter elementsQ68883320
The beta-globin dominant control region activates homologous and heterologous promoters in a tissue-specific mannerQ69962041
Assaying the polyadenylation state of mRNAsQ74602849
RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivoQ77962891
Three novel components of the human exosomeQ24290597
A coactivator of pre-mRNA splicingQ24321729
SRm160 splicing coactivator promotes transcript 3'-end cleavageQ24538266
Capping, splicing, and 3' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTDQ24601077
Differential recruitment of pre-mRNA splicing factors to alternatively spliced transcripts in vivoQ24814750
Quality control of mRNA 3'-end processing is linked to the nuclear exosomeQ27932977
Yeast poly(A)-binding protein, Pab1, and PAN, a poly(A) nuclease complex recruited by Pab1, connect mRNA biogenesis to exportQ27934476
Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradationQ27938985
Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1.Q27939910
The C-terminal domain of RNA polymerase II couples mRNA processing to transcriptionQ28301744
5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase IIQ28623635
From birth to death: the complex lives of eukaryotic mRNAsQ29615021
Mutations in RNA polymerase II enhance or suppress mutations in GAL4.Q33850755
Definition of the minimal requirements within the human beta-globin gene and the dominant control region for high level expressionQ33917150
A block to mRNA nuclear export in S. cerevisiae leads to hyperadenylation of transcripts that accumulate at the site of transcriptionQ33945461
Formation of export-competent mRNP: escaping nuclear destructionQ33987252
Evolution of the RNA polymerase II C-terminal domainQ34027969
Analysis of the requirement for RNA polymerase II CTD heptapeptide repeats in pre-mRNA splicing and 3'-end cleavageQ34365622
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitinQ34606712
Early formation of mRNP: license for export or quality control?Q35137961
A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3' end processing.Q35561598
Cotranscriptional mRNP assembly: from the DNA to the nuclear poreQ36131482
Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivoQ36255596
The road much traveled: trafficking in the cell nucleusQ36452215
Localization of an alpha-amanitin resistance mutation in the gene encoding the largest subunit of mouse RNA polymerase II.Q36483656
Genetic analysis of the repetitive carboxyl-terminal domain of the largest subunit of mouse RNA polymerase IIQ36780765
Ribozyme cleavage reveals connections between mRNA release from the site of transcription and pre-mRNA processing.Q40342109
The last CTD repeat of the mammalian RNA polymerase II large subunit is important for its stability.Q40602523
Inefficient processing impairs release of RNA from the site of transcriptionQ40954153
Requirement of the carboxy-terminal domain of RNA polymerase II for the transcriptional activation of chromosomal c-fos and hsp70A genesQ40963699
RNA polymerase II C-terminal domain required for enhancer-driven transcriptionQ41350631
Induction of Erythroid-Specific Expression in Murine Erythroleukemia (MEL) Cell LinesQ41700182
A novel function for the U2AF 65 splicing factor in promoting pre-mRNA 3'-end processing.Q41837652
In vivo recruitment of exon junction complex proteins to transcription sites in mammalian cell nucleiQ43207192
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P1104number of pages9
P304page(s)199-207
P577publication date2007-10-15
P1433published inJournal of Cell BiologyQ1524550
P1476titleSplicing- and cleavage-independent requirement of RNA polymerase II CTD for mRNA release from the transcription site
P478volume179

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cites work (P2860)
Q37620941"Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions
Q33736539Dynamic changes in the human methylome during differentiation
Q30502363Functional cooperation between the proteins Nck and ADAP is fundamental for actin reorganization
Q34310604Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain
Q36302418Introns and gene expression: cellular constraints, transcriptional regulation, and evolutionary consequences
Q93893035New mRNA modification?
Q37651988Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function
Q24650853Poly(A) signal-dependent degradation of unprocessed nascent transcripts accompanies poly(A) signal-dependent transcriptional pausing in vitro
Q37168944Polyadenylation releases mRNA from RNA polymerase II in a process that is licensed by splicing
Q37194592Quality control of mRNP in the nucleus
Q42787982Requirement of TFIIH kinase subunit Mat1 for RNA Pol II C-terminal domain Ser5 phosphorylation, transcription and mRNA turnover
Q33633977Splice-site mutations cause Rrp6-mediated nuclear retention of the unspliced RNAs and transcriptional down-regulation of the splicing-defective genes
Q52547079Splicing and transcription touch base: co-transcriptional spliceosome assembly and function.
Q37147259The CTD role in cotranscriptional RNA processing and surveillance
Q24316355The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation
Q34045365The RNA-binding protein ELAV regulates Hox RNA processing, expression and function within the Drosophila nervous system
Q28728197Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation