scholarly article | Q13442814 |
P2093 | author name string | Katherine A Jones | |
Joseph S Lucas | |||
Sunnie M Yoh | |||
P2860 | cites work | The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export | Q24293507 |
TREX is a conserved complex coupling transcription with messenger RNA export | Q24295211 | ||
A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing | Q24307408 | ||
The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression | Q24307439 | ||
USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A | Q24311562 | ||
Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II | Q24337471 | ||
Human mRNA export machinery recruited to the 5' end of mRNA | Q24338302 | ||
Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. | Q24537640 | ||
Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1 | Q24538939 | ||
Capping, splicing, and 3' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD | Q24601077 | ||
Crystal Structure and RNA Binding of the Tex Protein from Pseudomonas aeruginosa | Q27649998 | ||
The role of chromatin during transcription | Q27860995 | ||
RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach | Q27931237 | ||
Evidence that Spt6p controls chromatin structure by a direct interaction with histones | Q27931346 | ||
Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription | Q27932406 | ||
Transcriptional activators are dispensable for transcription in the absence of Spt6-mediated chromatin reassembly of promoter regions | Q27934442 | ||
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex | Q27935315 | ||
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export | Q27936733 | ||
SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope | Q27937982 | ||
Spn1 regulates the recruitment of Spt6 and the Swi/Snf complex during transcriptional activation by RNA polymerase II | Q27939723 | ||
Roles for Ctk1 and Spt6 in regulating the different methylation states of histone H3 lysine 36. | Q27939763 | ||
The yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p | Q27939919 | ||
The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11. | Q27940177 | ||
Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences | Q28208318 | ||
Controlling the elongation phase of transcription with P-TEFb | Q28255518 | ||
A putative transcriptional elongation factor hIws1 is essential for mammalian cell proliferation | Q28280169 | ||
Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation | Q28593817 | ||
Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II | Q29614679 | ||
Phosphorylation and functions of the RNA polymerase II CTD | Q29614764 | ||
Nap1 links transcription elongation, chromatin assembly, and messenger RNP complex biogenesis | Q30441325 | ||
A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation | Q30448402 | ||
Drosophila Kismet regulates histone H3 lysine 27 methylation and early elongation by RNA polymerase II | Q33375061 | ||
The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II. | Q34168365 | ||
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors | Q34419716 | ||
Role of the mammalian RNA polymerase II C-terminal domain (CTD) nonconsensus repeats in CTD stability and cell proliferation | Q34443898 | ||
Molecular evolution of the RNA polymerase II CTD. | Q34778014 | ||
Tails of intrigue: phosphorylation of RNA polymerase II mediates histone methylation | Q35131664 | ||
Nuclear mRNA surveillance | Q35145841 | ||
A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3' end processing. | Q35561598 | ||
Facts about FACT and transcript elongation through chromatin | Q35804601 | ||
Cotranscriptional mRNP assembly: from the DNA to the nuclear pore | Q36131482 | ||
Histone H3 variants and modifications on transcribed genes | Q36158492 | ||
A structural perspective of CTD function | Q36167411 | ||
Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II. | Q36421310 | ||
Reciprocal patterns of methylation of H3K36 and H3K27 on proximal vs. distal IgVH genes are modulated by IL-7 and Pax5. | Q36735246 | ||
Transcriptional regulation at the nuclear pore complex | Q36743038 | ||
A site to remember: H3K36 methylation a mark for histone deacetylation | Q36754994 | ||
Epigenetic signatures of stem-cell identity. | Q36761192 | ||
Sus1 is recruited to coding regions and functions during transcription elongation in association with SAGA and TREX2. | Q36942429 | ||
H3K27 demethylases, at long last | Q36965110 | ||
Poised polymerases: on your mark...get set...go! | Q37136094 | ||
Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus | Q37144184 | ||
The CTD role in cotranscriptional RNA processing and surveillance | Q37147259 | ||
Cracking the RNA polymerase II CTD code | Q37155088 | ||
Genome-wide mRNA surveillance is coupled to mRNA export | Q37598853 | ||
Transcription regulation through promoter-proximal pausing of RNA polymerase II. | Q39442921 | ||
Splicing- and cleavage-independent requirement of RNA polymerase II CTD for mRNA release from the transcription site | Q39751851 | ||
Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast | Q39895202 | ||
Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells | Q40001798 | ||
Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export | Q40386970 | ||
The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila | Q40682391 | ||
The Drosophila trithorax group protein Kismet facilitates an early step in transcriptional elongation by RNA Polymerase II. | Q46486956 | ||
H2B ubiquitylation plays a role in nucleosome dynamics during transcription elongation | Q46493188 | ||
Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription | Q46802691 | ||
Gcn5 promotes acetylation, eviction, and methylation of nucleosomes in transcribed coding regions. | Q53577981 | ||
The interaction between cap-binding complex and RNA export factor is required for intronless mRNA export | Q79960783 | ||
P433 | issue | 24 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Polymerase (RNA) II (DNA directed) polypeptide A | Q15335024 |
histone H3-K36 trimethylation | Q21118251 | ||
SET domain containing 2, histone lysine methyltransferase | Q21118252 | ||
Interacts with SUPT6H, CTD assembly factor 1 | Q21118500 | ||
SPT6, histone chaperone and transcription elongation factor | Q21991476 | ||
P304 | page(s) | 3422-34 | |
P577 | publication date | 2008-12-15 | |
P1433 | published in | Genes & Development | Q1524533 |
P1476 | title | The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation | |
P478 | volume | 22 |
Q37620941 | "Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions |
Q92532794 | A CRISPR/Cas9 screen identifies the histone demethylase MINA53 as a novel HIV-1 latency-promoting gene (LPG) |
Q38615900 | A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription. |
Q40191175 | A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo |
Q92133908 | Analog-sensitive cell line identifies cellular substrates of CDK9 |
Q33734638 | Arabidopsis IWS1 interacts with transcription factor BES1 and is involved in plant steroid hormone brassinosteroid regulated gene expression |
Q35067664 | Cap-binding protein complex links pre-mRNA capping to transcription elongation and alternative splicing through positive transcription elongation factor b (P-TEFb) |
Q64884468 | Casein kinase 2 mediated phosphorylation of Spt6 modulates histone dynamics and regulates spurious transcription. |
Q95297489 | Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness |
Q95355768 | Chromatin Regulation and the Histone Code in HIV Latency |
Q26999294 | Chromatin and epigenetic regulation of pre-mRNA processing |
Q35748234 | Chromatin and transcription in yeast |
Q38286121 | Chromatin modification by the RNA Polymerase II elongation complex |
Q42059823 | Chromatin reassembly factors are involved in transcriptional interference promoting HIV latency |
Q36736210 | Clinical and pathologic impact of select chromatin-modulating tumor suppressors in clear cell renal cell carcinoma |
Q38052877 | Connections between chromatin signatures and splicing |
Q27937813 | Control of chromatin structure by spt6: different consequences in coding and regulatory regions |
Q27934029 | Cooperation between the INO80 complex and histone chaperones determines adaptation of stress gene transcription in the yeast Saccharomyces cerevisiae |
Q38815706 | Coupling of RNA Polymerase II Transcription Elongation with Pre-mRNA Splicing |
Q27024720 | Coupling pre-mRNA processing to transcription on the RNA factory assembly line |
Q27667298 | Crystal Structures of the S. cerevisiae Spt6 Core and C-Terminal Tandem SH2 Domain |
Q33627681 | Crystallization and preliminary crystallographic analysis of eukaryotic transcription and mRNA export factor Iws1 from Encephalitozoon cuniculi |
Q58748277 | Cycles of gene expression and genome response during mammalian tissue regeneration |
Q89558876 | DNA mismatch repair in the context of chromatin |
Q34883246 | Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy |
Q36406402 | Dynamic changes in histone modifications precede de novo DNA methylation in oocytes. |
Q38166840 | Dynamic changes of the epigenetic landscape during cellular differentiation. |
Q37742439 | Epigenetic regulation of development by histone lysine methylation. |
Q58747998 | Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality |
Q34310604 | Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain |
Q57288714 | Genome Instability Is Promoted by the Chromatin-Binding Protein Spn1 in |
Q35711242 | Genome Scan for Parent-of-Origin QTL Effects on Bovine Growth and Carcass Traits |
Q24299046 | Genome instability and transcription elongation impairment in human cells depleted of THO/TREX |
Q34588508 | Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells |
Q37255665 | Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia. |
Q96610153 | Genomic profiling in renal cell carcinoma |
Q38329818 | H3K36 methylation is critical for brassinosteroid-regulated plant growth and development in rice. |
Q24319622 | HDGF-related protein-2 (HRP-2) acts as an oncogene to promote cell growth in hepatocellular carcinoma |
Q47781545 | HIV Latency Gets a New Histone Mark. |
Q35164614 | High nitrogen insensitive 9 (HNI9)-mediated systemic repression of root NO3- uptake is associated with changes in histone methylation |
Q41500628 | High-throughput assessment of context-dependent effects of chromatin proteins |
Q35910655 | Histone Chaperones Spt6 and FACT: Similarities and Differences in Modes of Action at Transcribed Genes |
Q28587253 | Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling |
Q35238231 | Histone H3 lysine 36 methyltransferase Whsc1 promotes the association of Runx2 and p300 in the activation of bone-related genes |
Q26865965 | Histone H3 mutations--a special role for H3.3 in tumorigenesis? |
Q36914566 | Histone H3K36 trimethylation is essential for multiple silencing mechanisms in fission yeast |
Q24300395 | Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation |
Q38343838 | Histone exchange, chromatin structure and the regulation of transcription |
Q45966440 | Host Methyltransferases and Demethylases: Potential New Epigenetic Targets for HIV Cure Strategies and Beyond. |
Q41468789 | Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications |
Q38715367 | Intragenic DNA methylation prevents spurious transcription initiation |
Q64054525 | Iws1 and Spt6 Regulate Trimethylation of Histone H3 on Lysine 36 through Akt Signaling and are Essential for Mouse Embryonic Genome Activation |
Q41147954 | MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress. |
Q30794597 | Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase |
Q27701733 | Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif |
Q50660807 | Mutations in SETD2 cause a novel overgrowth condition. |
Q26852971 | New insights into establishment and maintenance of DNA methylation imprints in mammals |
Q27664927 | Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II |
Q37809760 | Nucleocytoplasmic mRNP export is an integral part of mRNP biogenesis |
Q41863525 | Nucleosomes are well positioned in exons and carry characteristic histone modifications |
Q41880113 | Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer. |
Q35170883 | Pre-mRNA splicing is a determinant of histone H3K36 methylation |
Q46110457 | Processing the H3K36me3 signature |
Q39648288 | Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes |
Q50645951 | RNA Pol II Dynamics Modulate Co-transcriptional Chromatin Modification, CTD Phosphorylation, and Transcriptional Direction. |
Q37873568 | Recent advances in the regulation of brassinosteroid signaling and biosynthesis pathways |
Q39634800 | Reciprocal intronic and exonic histone modification regions in humans. |
Q34258783 | Regulation of the nuclear activities of brassinosteroid signaling |
Q33883693 | Relationship between gene body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks |
Q52361188 | Repeat-Specific Functions for the C-Terminal Domain of RNA Polymerase II in Budding Yeast. |
Q46273301 | Repetitive sequences in malaria parasite proteins. |
Q51696368 | SETD2 and DNMT3A screen in the Sotos-like syndrome French cohort. |
Q57472357 | SETD2-dependent H3K36me3 plays a critical role in epigenetic regulation of the HPV31 life cycle |
Q35188529 | SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability |
Q28075731 | SETD2: an epigenetic modifier with tumor suppressor functionality |
Q39118911 | SETting the Stage for Cancer Development: SETD2 and the Consequences of Lost Methylation |
Q37577424 | SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing. |
Q99572030 | SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells |
Q37158054 | Set2 mediated H3 lysine 36 methylation: regulation of transcription elongation and implications in organismal development |
Q39225775 | Shaping the cellular landscape with Set2/SETD2 methylation |
Q35310103 | Solution structure of tandem SH2 domains from Spt6 protein and their binding to the phosphorylated RNA polymerase II C-terminal domain |
Q30300037 | Spt6 Is Essential for rRNA Synthesis by RNA Polymerase I. |
Q57491805 | Spt6 Is Required for the Fidelity of Promoter Selection |
Q96303190 | Spt6 is a maintenance factor for centromeric CENP-A |
Q38629913 | Spt6 is required for heterochromatic silencing in the fission yeast Schizosaccharomyces pombe. |
Q37469459 | Spt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast |
Q41975283 | Spt6: two fundamentally distinct functions in the regulation of histone modification |
Q27665995 | Structure and Biological Importance of the Spn1-Spt6 Interaction, and Its Regulatory Role in Nucleosome Binding |
Q59070952 | Structure of activated transcription complex Pol II–DSIF–PAF–SPT6 |
Q60300334 | Structure of transcribing RNA polymerase II-nucleosome complex |
Q38751593 | Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation |
Q64120695 | Supplementing Genistein for Breeder Hens Alters the Fatty Acid Metabolism and Growth Performance of Offsprings by Epigenetic Modification |
Q39814573 | TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II |
Q36291340 | The Abundant Histone Chaperones Spt6 and FACT Collaborate to Assemble, Inspect, and Maintain Chromatin Structure in Saccharomyces cerevisiae. |
Q47650921 | The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins. |
Q46356479 | The Genetic Basis of Hepatosplenic T-cell Lymphoma. |
Q38043907 | The Mediator complex and transcription elongation |
Q34303212 | The RNA polymerase II CTD coordinates transcription and RNA processing. |
Q27664689 | The Transcription Factor Spn1 Regulates Gene Expression via a Highly Conserved Novel Structural Motif |
Q35910444 | The Transition of Poised RNA Polymerase II to an Actively Elongating State Is a "Complex" Affair |
Q39156173 | The code and beyond: transcription regulation by the RNA polymerase II carboxy-terminal domain |
Q91651165 | The elongation factor Elof1 is required for mammalian gastrulation |
Q47232619 | The elongation factor Spn1 is a multi-functional chromatin binding protein |
Q52319133 | The essential and multi-functional TFIIH complex. |
Q36070586 | The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation |
Q24336631 | The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis |
Q24294424 | The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation |
Q24339204 | The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα |
Q47370934 | The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation |
Q27665628 | The structure of an Iws1/Spt6 complex reveals an interaction domain conserved in TFIIS, Elongin A and Med26 |
Q33677160 | Transcription and chromatin determinants of de novo DNA methylation timing in oocytes |
Q34539956 | Transcription-coupled changes to chromatin underpin gene silencing by transcriptional interference |
Q42133855 | Transcriptional elongation and mRNA export are coregulated processes. |
Q34257867 | Transcriptional provirus silencing as a crosstalk of de novo DNA methylation and epigenomic features at the integration site |
Q99207801 | Two HIRA-dependent pathways mediate H3.3 de novo deposition and recycling during transcription |
Q24336514 | UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA |
Q42133715 | Updating the CTD Story: From Tail to Epic. |
Q37550216 | Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects |
Q61813696 | loss sensitizes cells to PI3Kβ and AKT inhibition |