IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses

scientific article published on January 1998

IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI1368
P932PMC publication ID508569
P698PubMed publication ID9435302
P5875ResearchGate publication ID13795778

P2093author name stringCox G
Baumann H
Xing Z
Gauldie J
Jordana M
Lei XF
Achong MK
P2860cites workImpaired immune and acute-phase responses in interleukin-6-deficient mice.Q52514391
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Role for macrophage inflammatory protein-2 in lipopolysaccharide-induced lung injury in ratsQ70988426
The acute phase responseQ71618259
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Neutralization of IL-10 increases survival in a murine model of Klebsiella pneumoniaQ71870349
Neutralization of IL-10 increases lethality in endotoxemia. Cooperative effects of macrophage inflammatory protein-2 and tumor necrosis factorQ71961272
Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivoQ72567277
Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55Q72690586
Granulocyte-macrophage colony-stimulating factor and IFN-gamma restore the systemic TNF-alpha response to endotoxin in lipopolysaccharide-desensitized miceQ73128674
Intra-alveolar macrophage-inflammatory peptide 2 induces rapid neutrophil localization in the lungQ30469647
Leukemia inhibitory factor protects against experimental lethal Escherichia coli septic shock in miceQ34608763
Interleukin-6 and its receptor: a paradigm for cytokinesQ35425050
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Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosusQ36364479
Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicansQ36366415
Characterization of early cytokine responses and an interleukin (IL)-6-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infectionQ36377083
Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactionsQ39761202
Protective role of interleukin 6 in the lipopolysaccharide-galactosamine septic shock model.Q40270314
The intratracheal administration of endotoxin and cytokines. I. Characterization of LPS-induced IL-1 and TNF mRNA expression and the LPS-, IL-1-, and TNF-induced inflammatory infiltrateQ41188038
Lipopolysaccharide induces expression of granulocyte/macrophage colony-stimulating factor, interleukin-8, and interleukin-6 in human nasal, but not lung, fibroblasts: evidence for heterogeneity within the respiratory tractQ41528855
The induction by human interleukin-6 of apoptosis in the promonocytic cell line U937 and human neutrophilsQ41598113
IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in miceQ41759621
Intratracheal injection of endotoxin and cytokines. II. Interleukin-6 and transforming growth factor beta inhibit acute inflammationQ41819655
Cytokine expression by neutrophils and macrophages in vivo: endotoxin induces tumor necrosis factor-alpha, macrophage inflammatory protein-2, interleukin-1 beta, and interleukin-6 but not RANTES or transforming growth factor-beta 1 mRNA expression iQ42498115
Protective effect of anti-interleukin (IL)-6 antibody against endotoxin, associated with paradoxically increased IL-6 levelsQ44301484
The role of interleukin-6 in mucosal IgA antibody responses in vivoQ45872747
Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemiaQ45881120
Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA)Q46724375
Local release of IL-10 by transfected mouse mammary adenocarcinoma cells does not suppress but enhances antitumor reaction and elicits a strong cytotoxic lymphocyte and antibody-dependent immune memory.Q52051584
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
P304page(s)311-320
P577publication date1998-01-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleIL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses
P478volume101

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Q28589039Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation
Q36692981Intoxication- and withdrawal-dependent expression of central and peripheral cytokines following initial ethanol exposure
Q59649473Intracerebroventricular interleukin-6 treatment decreases body fat in rats
Q28487796Intratracheal IL-6 protects against lung inflammation in direct, but not indirect, causes of acute lung injury in mice
Q40727524Invasion of Salmonella into human intestinal epithelial cells is modulated by HLA-B27.
Q35829699Involvement of IL-6, apart from its role in immunity, in mediating a chronic response during experimental arthritis
Q38622845Involvement of semicarbazide-sensitive amine oxidase-mediated deamination in lipopolysaccharide-induced pulmonary inflammation
Q30423309Isoflurane induces learning impairment that is mediated by interleukin 1β in rodents
Q35077642Kaposi's sarcoma-associated herpesvirus infection of endothelial cells inhibits neutrophil recruitment through an interleukin-6-dependent mechanism: a new paradigm for viral immune evasion
Q39052387Keratinocytes produce IL-6 in response to desmoglein 1 cleavage by Staphylococcus aureus exfoliative toxin A.
Q39476004Kinetic study of the inflammatory response in Streptococcus pneumoniae experimental pneumonia treated with the ketolide HMR 3004.
Q42275135LPS-induced release of IL-6 from glia modulates production of IL-1β in a JAK2-dependent manner
Q42461568Lack of soluble tumor necrosis factor alpha receptor 1 and 2 and interleukin-1beta compartmentalization in lungs of mice after a single intratracheal inoculation with live Porphyromonas gingivalis
Q39826955Linking lung function and inflammatory responses in ventilator-induced lung injury
Q42620778Lipid-mediated oxidative stress and inflammation in the pathogenesis of Parkinson's disease
Q39887518Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice
Q40406473Localized inflammation in peripheral tissue signals the CNS for sickness response in the absence of interleukin-1 and cyclooxygenase-2 in the blood and brain
Q42816427Long-term continuous exposure to static magnetic field reduces popolysaccharide-induced cytotoxicity of fibroblasts
Q51321008Long-term endurance training increases serum cathepsin S and decreases IL-6 and hsCRP levels.
Q34242309Long-term physical activity and inflammatory biomarkers in older adults
Q64100153Loss of interleukin-6 enhances the inflammatory response associated with hyperoxia-induced lung injury in neonatal mice
Q34837522Macrophage subset sensitivity to endotoxin tolerisation by Porphyromonas gingivalis
Q64962353Macrophage subsets exhibit distinct E. coli-LPS tolerisable cytokines associated with the negative regulators, IRAK-M and Tollip.
Q58553023Maestro endothelium conducts the neutrophils
Q36003803Male adolescent rats display blunted cytokine responses in the CNS after acute ethanol or lipopolysaccharide exposure
Q38505801Mannose-binding lectin without the aid of its associated serine proteases alters lipopolysaccharide-mediated cytokine/chemokine secretion from human endothelial cells
Q36875514Marginal zone B cells exacerbate endotoxic shock via interleukin-6 secretion induced by Fcα/μR-coupled TLR4 signalling
Q36938993Markers of respiratory inflammation in horses in relation to seasonal changes in air quality in a conventional racing stable.
Q40553691Mast cell dipeptidyl peptidase I mediates survival from sepsis
Q52682515Maternal Immune Activation During the Third Trimester Is Associated with Neonatal Functional Connectivity of the Salience Network and Fetal to Toddler Behavior.
Q38598669Mechanisms and mediators of lung injury after acute kidney injury
Q34053416Mechanisms of repair and remodeling following acute lung injury
Q43889817Mediators of inflammation in children with type I diabetes mellitus: cytokines in type I diabetic children
Q42253863Mesenchymal stem cell-educated macrophages: a novel type of alternatively activated macrophages
Q89144604Mesenchymal stromal cells for treatment of the acute respiratory distress syndrome: The beginning of the story
Q39173877Meta-analysis of interleukin 6, 8, and 10 between off-pump and on-pump coronary artery bypass groups
Q28066564Metabolic Adaptation in Obesity and Type II Diabetes: Myokines, Adipokines and Hepatokines
Q27336723Mice chronically fed high-fat diet have increased mortality and disturbed immune response in sepsis
Q30474537Micro-ultrasonographic imaging of atherosclerotic progression and correlation with inflammatory markers in apolipoprotein-E knockout mice
Q26851141MicroRNAs regulate dendritic cell differentiation and function
Q26800158Modulating the Innate Immune Response to Influenza A Virus: Potential Therapeutic Use of Anti-Inflammatory Drugs
Q37299999Modulation of anti-inflammatory response in lipopolysaccharide stimulated human THP-1 cell line and mouse model at gene expression level with indigenous putative probiotic lactobacilli
Q73572054Modulation of lung local immune responses by oral administration of a herbal medicine Sho-saiko-to
Q34940688Modulation of polymorphonuclear cell interleukin-8 secretion by human monoclonal antibodies to type 8 pneumococcal capsular polysaccharide
Q35739062Molecular and cellular characterization of a Salmonella enterica serovar Paratyphi a outbreak strain and the human immune response to infection
Q40698036Multiple transcription factors regulating the IL-6 gene are activated by cAMP in cultured Caco-2 cells
Q33671394Mutant monocyte chemoattractant protein 1 protein attenuates migration of and inflammatory cytokine release by macrophages exposed to orthopedic implant wear particles.
Q33964529Mycoplasma fermentans and TNF-beta interact to amplify immune-modulating cytokines in human lung fibroblasts
Q88900337Müller cells and diabetic retinopathy
Q24801702NF-kappaB p50 facilitates neutrophil accumulation during LPS-induced pulmonary inflammation
Q26823812Neonatal host defense against Staphylococcal infections
Q50115901Neopterin Counters Vascular Inflammation and Atherosclerosis
Q37116106Neuroinflammation, neurodegeneration, and depression.
Q44867311Neurotrophic role of interleukin-6 and soluble interleukin-6 receptors in N1E-115 neuroblastoma cells
Q40066414Neutrophil chemotaxis and transcriptomics in term and preterm neonates
Q37332352Neutrophil-derived IL-6 limits alveolar barrier disruption in experimental ventilator-induced lung injury
Q38317241Novel investigational drugs targeting IL-6 signaling for the treatment of depression
Q36951691Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease.
Q43241028Off-pump coronary surgery causes immediate release of myocardial damage markers
Q35197837On the site and mechanism of action of the anti-obesity effects of interleukin-6.
Q33596672Oncostatin M: development of a pleiotropic cytokine
Q33878479Oral microbial biofilm stimulation of epithelial cell responses.
Q37551125Original Research: Extract of Bambusae Caulis in Taeniam inhibits cigarette smoke-induced pulmonary and intestinal inflammation
Q34602991Overload-induced skeletal muscle extracellular matrix remodelling and myofibre growth in mice lacking IL-6
Q34875121Oxidative stress and neutrophil activation--the two keystones of ischemia/reperfusion injury.
Q44771546Ozone-induced acute pulmonary injury in inbred mouse strains
Q34378721PD-L1hi retinal pigment epithelium (RPE) cells elicited by inflammatory cytokines induce regulatory activity in uveitogenic T cells
Q80615154Partial divergence of cytokine mRNA expression in bronchial tissues compared to bronchoalveolar lavage cells in horses with recurrent airway obstruction
Q87901189Patchouli alcohol dampens lipopolysaccharide induced mastitis in mice
Q35017740Pathogenesis and pathophysiology of pneumococcal meningitis
Q92106852Pathogenic Fungal Infection in the Lung
Q36572885Pathogenic role of NF-kappaB activation in tubulointerstitial inflammatory lesions in human lupus nephritis
Q97524536Pathophysiology and pathological findings of heatstroke in dogs
Q37375163Pathophysiology of the systemic inflammatory response after major accidental trauma.
Q36153982Patients with chronic three-vessel disease in a 15-year follow-up study: genetic and non-genetic predictors of survival
Q45902247Patterns of cytokine profiles differ with pregnancy outcome and ethnicity.
Q93197801Peptides With Triplet-Tryptophan-Pivot Promoted Pathogenic Bacteria Membrane Defects
Q41333693Perilla frutescens Extracts Protects against Dextran Sulfate Sodium-Induced Murine Colitis: NF-κB, STAT3, and Nrf2 as Putative Targets
Q36900075Pharmacogenetics of chronic pain and its treatment.
Q80347661Plasma levels of fibrinogen and C-reactive protein are related to interleukin-6 gene -572C>G polymorphism in subjects with and without hypertension
Q84596969Plasma soluble IL-6 receptor concentration in rheumatoid arthritis: associations with the rs8192284 IL6R polymorphism and with disease activity
Q40284169Plasmin and plasminogen induce macrophage reprogramming and regulate key steps of inflammation resolution via annexin A1.
Q24799449Platelet count and interleukin 6 gene polymorphism in healthy subjects
Q33806035Pleiotropic effects of interleukin-6 in a "two-hit" murine model of acute respiratory distress syndrome
Q33795810Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6-mediated crosstalk
Q44572977Polymorphisms in the RAC1 gene are associated with hypertension risk factors in a Chilean pediatric population.
Q34235473Polymorphisms of -174G>C and -572G>C in the interleukin 6 (IL-6) gene and coronary heart disease risk: a meta-analysis of 27 research studies
Q37199797Porphyromonas gulae Has Virulence and Immunological Characteristics Similar to Those of the Human Periodontal Pathogen Porphyromonas gingivalis.
Q55620445Possible potentiation by certain antioxidants of the anti-inflammatory effects of diclofenac in rats.
Q47727500Postoperative suppression of inflammatory cytokines after distal gastrectomy in elderly patients
Q47829271Potential Role of Humoral IL-6 Cytokine in Mediating Pro-Inflammatory Endothelial Cell Response in Amyotrophic Lateral Sclerosis.
Q44373643Predicting death from tumour necrosis factor-alpha and interleukin-6 in 80-year-old people
Q36925542Primer: the practical use of biological markers of rheumatic and systemic inflammatory diseases
Q28350142Pro-inflammatory cytokines induce c-fos expression followed by IL-6 release in human airway smooth muscle cells
Q39432258Probiotic bacterial strains differentially modulate macrophage cytokine production in a strain-dependent and cell subset-specific manner
Q37646964Proinflammatory cytokines and osteoporosis
Q35575095Proinflammatory gene polymorphisms are potentially associated with Korean non-Sjogren dry eye patients
Q37356057Prostaglandin E(2) in tick saliva regulates macrophage cell migration and cytokine profile
Q44838313Prostaglandin E2 receptors EP2 and EP4 are up-regulated in peritoneal macrophages and joints of pristane-treated mice and modulate TNF-alpha and IL-6 production
Q40744807Proteasome inhibitors induce heat shock response and increase IL-6 expression in human intestinal epithelial cells
Q86077790Protection of intestinal injury during heat stroke in mice by interleukin-6 pretreatment
Q45651755Protective effect of exogenous recombinant mouse interferon-gamma and tumour necrosis factor-alpha on ectromelia virus infection in susceptible BALB/c mice
Q21142646Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis
Q22000727Protective effects of aerobic exercise on acute lung injury induced by LPS in mice
Q39515200Protective effects of dietary arginine supplementation against oxidative stress in weaned piglets
Q40769002Protein phosphatase 2A and protein kinase Calpha are physically associated and are involved in Pseudomonas aeruginosa-induced interleukin 6 production by mast cells
Q38633253Pseudomonas aeruginosa LasB protease impairs innate immunity in mice and humans by targeting a lung epithelial cystic fibrosis transmembrane regulator-IL-6-antimicrobial-repair pathway
Q35552862Pullulan: a new cytoadhesive for cell-mediated cartilage repair.
Q57549446RAPID PULMONARY EXPRESSION OF ACUTE-PHASE REACTANTS AFTER LOCAL LIPOPOLYSACCHARIDE EXPOSURE IN MICE IS FOLLOWED BY AN INTERLEUKIN-6 MEDIATED SYSTEMIC ACUTE-PHASE RESPONSE
Q44291813Raised IL-2 and TNF-α concentrations are associated with postoperative delirium in patients undergoing coronary-artery bypass graft surgery
Q64103670Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders
Q91736923Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer
Q44071446Recipient IL-6-572C/G genotype is associated with reduced incidence of acute rejection following liver transplantation
Q33946711Reduction of particle-induced osteolysis by interleukin-6 involves anti-inflammatory effect and inhibition of early osteoclast precursor differentiation
Q40666740Regional and systemic cytokine responses to acute inflammation of the vermiform appendix
Q42832547Regulation of NF-kappaB-dependent gene expression by the POU domain transcription factor Oct-1.
Q36954878Regulation of a lymphocyte-endothelial-IL-6 trans-signaling axis by fever-range thermal stress: hot spot of immune surveillance
Q33736175Regulation of adiponectin secretion by adipocytes in the polycystic ovary syndrome: role of tumor necrosis factor-{alpha}.
Q39982882Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation
Q38258654Regulation of hemichannels and gap junction channels by cytokines in antigen-presenting cells.
Q42244628Relationship between the interleukin-6-174 gene and mannose-binding lectin codon 54 gene polymorphisms and condyloma acuminatum.
Q44884504Relationship of plasma interleukin-6 and its genetic variants with hypertension in Hong Kong Chinese
Q38290421Relevance of the anti-inflammatory properties of curcumin in neurodegenerative diseases and depression.
Q73223339Renal cytokine responses in acute Escherichia coli pyelonephritis in IL-6-deficient mice
Q34497022Resistance exercise training-induced muscle hypertrophy was associated with reduction of inflammatory markers in elderly women
Q37429326Retinal Astrocytes respond to IL-17 differently than Retinal Pigment Epithelial cells
Q33723088Role of cytokines in pulmonary antimicrobial host defense
Q33940417Role of innate host defenses in susceptibility to early-onset neonatal sepsis.
Q79557605Role of interleukin-6 in a glucan-induced model of granulomatous vasculitis
Q38853625Role of interleukin-6 in cancer progression and therapeutic resistance
Q43913922Role of interleukin-6 in cardiac inflammation and dysfunction after burn complicated by sepsis
Q44410276Role of interleukin-6 in hepatic heat shock protein expression and protection against acetaminophen-induced liver disease
Q42164189Role of interleukin-6 in murine airway responses to ozone
Q38206408Role of interleukin-6 in regulation of immune responses to remodeling after myocardial infarction
Q37172129Roles of interleukin-6 in activation of STAT proteins and recruitment of neutrophils during Escherichia coli pneumonia
Q34729528STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13.
Q36481079STAT3: a potential therapeutic target in dendritic cells for the induction of transplant tolerance
Q34871862Safety and biocompatibility of carbohydrate-functionalized polyanhydride nanoparticles
Q43728285Schistosoma mansoni induces the synthesis of IL-6 in pulmonary microvascular endothelial cells: role of IL-6 in the control of lung eosinophilia during infection.
Q37714378Scorpion venom and the inflammatory response
Q41336582Secreted IL-1α promotes T-cell activation and expansion of CD11b(+) Gr1(+) cells in carbon tetrachloride-induced liver injury in mice.
Q43660385Secretion of cytokines by uroepithelial cells stimulated by Escherichia coli and Citrobacter spp.
Q34259098Secretion of immunoregulatory cytokines by mesenchymal stem cells.
Q95366720Sepsis definitions
Q37665355Sepsis in old age: review of human and animal studies
Q48163396Serum Antioxidant Parameters are Significantly Increased in Patients with Type 2 Diabetes Mellitus after Consumption of Chinese Propolis: A Randomized Controlled Trial Based on Fasting Serum Glucose Level.
Q47597288Serum cytokine levels in active uveitis and remission
Q85075323Sexual dimorphism on cytokines expression in the temporomandibular joint: the role of gonadal steroid hormones
Q54530046Shift toward an alternatively activated macrophage response in lungs of NO2-exposed rats.
Q34166632Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
Q34949631Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines-an exploratory study
Q34238426Soluble mediators regulating immunity in early life
Q37495889Stretch and Inflammation- Their Relation to Fractionation of Electrograms in Atrial Fibrillation
Q48077964Structural characterization and immunomodulatory effects of polysaccharides from Phellinus linteus and Phellinus igniarius on the IL-6/IL-10 cytokine balance of the mouse macrophage cell lines (RAW 264.7).
Q21266603Structure and evolution of the mouse pregnancy-specific glycoprotein (Psg) gene locus
Q39297837Students' perspective on genomics: from sample to sequence using the case study of blueberry.
Q59296539Suppression of endotoxin-inducible cytokines in whole blood from human subjects following single dose of recombinant human interleukin-11
Q54418101Suppression of tumour necrosis factor-alpha by Schizonepeta tenuifolia water extract via inhibition of IkappaBalpha degradation and Jun N-terminal kinase/stress-activated protein kinase activation.
Q36183084Surgical trauma and immunosuppression: pathophysiology and potential immunomodulatory approaches
Q35790446Surgical trauma: hyperinflammation versus immunosuppression?
Q89606855Sustained-release Griffithsin nanoparticle-fiber composites against HIV-1 and HSV-2 infections
Q33507093Synergistic antibacterial and anti-inflammatory activity of temporin A and modified temporin B in vivo
Q40790873Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown
Q36764603Systematic review of proinflammatory cytokines in obsessive-compulsive disorder
Q29048648Systemic IL-6 Effector Response in Mediating Systemic Bone Loss Following Inhalation of Organic Dust
Q47792069Systemic cytokine response following exercise-induced muscle damage in humans.
Q57339893T-cell-specific deletion of gp130 renders the highly susceptible IL-10-deficient mouse resistant to intestinal nematode infection
Q37051650TGF-β1 limits the onset of innate lung inflammation by promoting mast cell-derived IL-6
Q40931701TLR ligand induced IL-6 counter-regulates the anti-viral CD8(+) T cell response during an acute retrovirus infection
Q35866610TNF, IL6, and IL1B Polymorphisms Are Associated with Severe Influenza A (H1N1) Virus Infection in the Mexican Population
Q37004059TNF-alpha-mediated inflammation in cerebral aneurysms: a potential link to growth and rupture
Q42363706TNF-α mRNA is negatively regulated by microRNA-181a-5p in maturation of dendritic cells induced by high mobility group box-1 protein
Q37018731Tanreqing Injection Attenuates Lipopolysaccharide-Induced Airway Inflammation through MAPK/NF-κB Signaling Pathways in Rats Model
Q37115911Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia
Q35067377Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality
Q43842955The -174 C/G locus affects in vitro/in vivo IL-6 production during aging
Q84511689The -174 G/C polymorphism in interleukin-6 (IL-6) promoter region is associated with serum IL-6 and carcinoembryonic antigen levels in patients with colorectal cancers in Taiwan
Q26753839The Burn Wound Microenvironment
Q36804420The IL-6/sIL-6R complex as a novel target for therapeutic approaches
Q56333918The Impact of Systemic Inflammation on Neurodevelopment
Q42395008The Janus Faces of IL-6 in GN.
Q38918906The PACAP-type I receptor agonist maxadilan from sand fly saliva protects mice against lethal endotoxemia by a mechanism partially dependent on IL-10.
Q47579164The Psychoneuroimmunology of Pregnancy
Q40611269The Role of Activated Microglia and Resident Macrophages in the Neurovascular Unit during Cerebral Ischemia: Is the Jury Still Out?
Q39028288The Role of Cytokines in the Development of Atherosclerosis
Q40906335The adenosine system selectively inhibits TLR-mediated TNF-alpha production in the human newborn.
Q43455239The anti-inflammatory and matrix restorative mechanisms of platelet-rich plasma in osteoarthritis.
Q83176974The anti-inflammatory effects of IV administered clenbuterol in horses with recurrent airway obstruction
Q33585054The change of serum tumor necrosis factor alpha in patients with type 1 diabetes mellitus: A systematic review and meta-analysis
Q34979049The combination of red palm oil and rooibos show anti-inflammatory effects in rats.
Q34474506The correlation between increased serum concentrations of interleukin-6 family cytokines and disease activity in rheumatoid arthritis patients
Q73497704The effect of acute immobilization stress on the abundance of corticotropin-releasing factor receptor in lymphoid organs
Q79895580The effect of aerosolized and intravenously administered clenbuterol and aerosolized fluticasone propionate on horses challenged with Aspergillus fumigatus antigen
Q43770319The effects of IL-6 and TNF-alpha as molecular adjuvants on immune responses to FMDV and maturation of dendritic cells by DNA vaccination
Q42085795The good, the bad, and the ugly of interleukin-6 signaling.
Q43866765The herbal medicine Shosaiko-to exerts different modulating effects on lung local immune responses among mouse strains
Q38000156The immune system in the aging human
Q37526512The major inflammatory mediator interleukin-6 and obesity
Q38253020The neuroimmunology of degeneration and regeneration in the peripheral nervous system.
Q40070384The phenotype of the RABV glycoprotein determines cellular and global virus load in the brain and is decisive for the pace of the disease
Q35149385The pro-inflammatory cytokine, interleukin-6, enhances the polarization of alternatively activated macrophages
Q44723170The rat antigen-presenting lectin-like receptor complex influences innate immunity and development of infectious diseases
Q38040033The regulation of interleukin-6 implicates skeletal muscle as an integrative stress sensor and endocrine organ
Q81886868The relationship between prolactin (PRL), leptin, nitric oxide (NO), and cytokines in patients with hyperprolactinemia
Q38685086The role and therapeutic targeting of IL-6 in rheumatoid arthritis.
Q39273700The role of TRB3 in mast cells sensitized with monomeric IgE.
Q39032617The role of Th17-associated cytokines in the pathogenesis of experimental autoimmune uveitis (EAU).
Q37812051The role of inflamed adipose tissue in the insulin resistance
Q49087290The role of interleukin-6 in pulmonary and systemic manifestations in a murine model of chronic obstructive pulmonary disease
Q51776876The role of serum inflammatory markers in acute appendicitis and their success in preventing negative laparotomy.
Q34991808The role of soluble receptors in cytokine biology: the agonistic properties of the sIL-6R/IL-6 complex
Q35127430The role of the interleukin‐6 family of cytokines in inflammatory arthritis and bone turnover
Q27333845The sst1 resistance locus regulates evasion of type I interferon signaling by Chlamydia pneumoniae as a disease tolerance mechanism
Q35547260The therapeutic potential of interleukin-6 in treating obesity
Q60920017Therapeutic effect of a Chlamydia pecorum recombinant major outer membrane protein vaccine on ocular disease in koalas (Phascolarctos cinereus)
Q46321276Time-dependent effect of in utero inflammation: a longitudinal study in rats
Q73015339Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors
Q34982686Trametes versicolor protein YZP activates regulatory B lymphocytes - gene identification through de novo assembly and function analysis in a murine acute colitis model
Q34768987Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigra
Q28552434Tumor Necrosis Factor, but Not Neutrophils, Alters the Metabolic Profile in Acute Experimental Arthritis
Q54497929Tumor necrosis factor-alpha deficiency retards early fatty-streak lesion by influencing the expression of inflammatory factors in apoE-null mice.
Q34471871Undernutrition, the acute phase response to infection, and its effects on micronutrient status indicators
Q28218287Uneven modulation of the annexin 1 system in osteoblast-like cells by dexamethasone
Q39097068Up-regulation interleukin-6 and interleukin-8 by activated protein C in lipopolysaccharide-treated human umbilical vein endothelial cells
Q33686393Upregulation of Salmonella-induced IL-6 production in Caco-2 cells by PJ-34, PARP-1 inhibitor: involvement of PI3K, p38 MAPK, ERK, JNK, and NF-kappaB
Q39520741Ureaplasma urealyticum modulates endotoxin-induced cytokine release by human monocytes derived from preterm and term newborns and adults
Q48171757Vascular endothelial effects of collaborative binding to platelet/endothelial cell adhesion molecule-1 (PECAM-1).
Q44045425White Button and Shiitake Mushrooms Reduce the Incidence and Severity of Collagen-Induced Arthritis in Dilute Brown Non-Agouti Mice,
Q28570037Y-box protein-1 is the crucial mediator of antifibrotic interferon-gamma effects
Q74342819[An increased proinflammatory activity is inherent in insulin resistance]
Q80618939[IL-6 anti-inflammatory activity in pleural effusion post-coronary artery bypass graft surgery]
Q90828190p75NTR regulates brain mononuclear cell function and neuronal structure in Toxoplasma infection-induced neuroinflammation