In vitro and in vivo properties of adenovirus vectors with increased affinity to CD46

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In vitro and in vivo properties of adenovirus vectors with increased affinity to CD46 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01308-08
P932PMC publication ID2573189
P698PubMed publication ID18753195

P50authorKah-Whye PengQ88612764
P2093author name stringYing Liu
Thilo Stehle
Andrew Baker
André Lieber
Hongjie Wang
Steve Roffler
Daniel Stone
Zongyi Li
Sebastian Tuve
John McVey
Dmitry Shayakhmetov
Christophe L M Verlinde
Oleksandr Kalyushniy
P2860cites workAdenovirus Binding to Blood Factors Results in Liver Cell Infection and HepatotoxicityQ27469833
Adenovirus type 11 binding alters the conformation of its receptor CD46Q27643524
Identification of CD46 Binding Sites within the Adenovirus Serotype 35 Fiber KnobQ27648583
Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display libraryQ32060783
Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vectorQ33799667
The distal short consensus repeats 1 and 2 of the membrane cofactor protein CD46 and their distance from the cell membrane determine productive entry of species B adenovirus serotype 35Q33908780
Evaluation of adenovirus vectors containing serotype 35 fibers for vaccinationQ34507185
Avidin-based targeting and purification of a protein IX-modified, metabolically biotinylated adenoviral vector.Q35019399
Affinity thresholds for membrane fusion triggering by viral glycoproteinsQ36315685
Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivoQ36535456
New serotypes of adenoviral vectorsQ36641334
Engineering targeted viral vectors for gene therapyQ36868494
Intracellular trafficking of adenovirus: many means to many endsQ36913904
Complex target SELEX.Q37056570
Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infectionQ37371791
Dependence of adenovirus infectivity on length of the fiber shaft domainQ39585255
Identification of contact residues and definition of the CAR-binding site of adenovirus type 5 fiber proteinQ39589919
The interaction between the fiber knob domain and the cellular attachment receptor determines the intracellular trafficking route of adenovirusesQ39732535
Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene deliveryQ39869620
Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli.Q39875310
Transgenic mice expressing human measles virus (MV) receptor CD46 provide cells exhibiting different permissivities to MV infections.Q39876381
Genome size and structure determine efficiency of postinternalization steps and gene transfer of capsid-modified adenovirus vectors in a cell-type-specific mannerQ39960246
A ligand-pseudoreceptor system based on de novo designed peptides for the generation of adenoviral vectors with altered tropism.Q40026203
Modification of adenovirus capsid with a designed protein ligand yields a gene vector targeted to a major molecular marker of cancerQ40055106
Interaction of penton base Arg-Gly-Asp motifs with integrins is crucial for adenovirus serotype 35 vector transduction in human hematopoietic cellsQ40084250
Downregulation of human CD46 by adenovirus serotype 35 vectorsQ40155682
A new group B adenovirus receptor is expressed at high levels on human stem and tumor cells.Q40223632
Evaluation of adenovirus vectors containing serotype 35 fibers for tumor targetingQ40250421
Adenovirus type 5 interactions with human blood cells may compromise systemic delivery.Q40297306
Localization of regions in CD46 that interact with adenovirusQ40416477
High CD46 receptor density determines preferential killing of tumor cells by oncolytic measles virusQ40534840
Deletion of penton RGD motifs affects the efficiency of both the internalization and the endosome escape of viral particles containing adenovirus serotype 5 or 35 fiber knobsQ40722127
Adenovirus-platelet interaction in blood causes virus sequestration to the reticuloendothelial system of the liverQ41786777
Abrupt emergence of diverse species B adenoviruses at US military recruit training centersQ43663175
Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammationQ44021757
CD46 is a cellular receptor for group B adenovirusesQ45869560
Adenovirus serotype 5 hexon mediates liver gene transferQ45875068
Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.Q45880303
Transduction properties of adenovirus serotype 35 vectors after intravenous administration into nonhuman primatesQ64376738
Sustained AAV-mediated dystrophin expression in a canine model of Duchenne muscular dystrophy with a brief course of immunosuppressionQ80141652
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectAdenoviridaeQ193447
P304page(s)10567-10579
P577publication date2008-08-27
P1433published inJournal of VirologyQ1251128
P1476titleIn vitro and in vivo properties of adenovirus vectors with increased affinity to CD46
P478volume82

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