Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli.

scientific article published on July 1996

Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.70.7.4805-4810.1996
P932PMC publication ID190422
P698PubMed publication ID8676512

P2093author name stringE Degryse
Mehtali M
Dieterle A
Pavirani A
Chartier C
M Mehtali
C Chartier
Degryse E
A Pavirani
A Dieterle
M Gantzer
Gantzer M
P2860cites workRapid cloning by homologous recombination in vivoQ40519954
Recombinant adenovirus deleted of all viral genes for gene therapy of cystic fibrosisQ41226051
Viability of λ phages carrying a perfect palindrome in the absence of recombination nucleasesQ41557657
Characterisation of two differently processed forms of human recombinant factor IX synthesised in CHO cells transformed with a polycistronic vectorQ44935686
The sequence of the genome of adenovirus type 5 and its comparison with the genome of adenovirus type 2Q44968237
An efficient procedure to select and recover recombinant adenovirus vectorsQ45866724
Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoterQ48351986
Plasmid-mediated lethality and plasmid multimer formation in an Escherichia coli recBC sbcBC mutant. Involvement of RecF recombination pathway genes.Q54342674
Human adenovirus cloning vectors based on infectious bacterial plasmids.Q54437284
In vivo intermolecular recombination in Escherichia coli: application to plasmid constructions.Q54590198
Evaluation of Escherichia coli recBC sbcBC mutants for cloning by recombination in vivo.Q54613855
A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5Q64379529
Biochemistry of homologous recombination in Escherichia coliQ24634614
Studies on transformation of Escherichia coli with plasmidsQ27860598
A new technique for the assay of infectivity of human adenovirus 5 DNAQ27860797
Selective extraction of polyoma DNA from infected mouse cell culturesQ29547500
Characteristics of a human cell line transformed by DNA from human adenovirus type 5Q29547863
Upstream and downstream cis-acting elements for cleavage at the L4 polyadenylation site of adenovirus-2.Q34801348
Adenovirus-Based Expression Vectors and Recombinant VaccinesQ35228887
Adenovirus vectors for gene expressionQ35291687
Efficient manipulation of the human adenovirus genome as an infectious yeast artificial chromosome cloneQ35559318
Generation of adenovirus by transfection of plasmidsQ35686623
An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.Q35748116
Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentationQ36230680
Plasmid and bacteriophage vectors for excision of intact insertsQ36298002
Rescue of functional replication origins from embedded configurations in a plasmid carrying the adenovirus genomeQ36941297
Region E3 of adenovirus: A cassette of genes involved in host immunosurveillance and virus-cell interactionsQ37099438
Development of adenovirus vectors for the expression of heterologous genesQ39585186
Alternative cell line for virus isolationQ40206587
In vivo cloning of PCR products in E. coliQ40412972
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
AdenoviridaeQ193447
P304page(s)4805-4810
P577publication date1996-07-01
P1433published inJournal of VirologyQ1251128
P1476titleEfficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli
P478volume70

Reverse relations

cites work (P2860)
Q40693835A 72-bp internal deletion in the left inverted terminal repeat of the bovine adenovirus type 3 genome does not affect virus replication
Q35874291A Multi Targeting Conditionally Replicating Adenovirus Displays Enhanced Oncolysis while Maintaining Expression of Immunotherapeutic Agents
Q42723089A conformational change in the adeno-associated virus type 2 capsid leads to the exposure of hidden VP1 N termini
Q47549547A hypoxia- and telomerase-responsive oncolytic adenovirus expressing secretable trimeric TRAIL triggers tumour-specific apoptosis and promotes viral dispersion in TRAIL-resistant glioblastoma
Q89899416A new gorilla adenoviral vector with natural lung tropism avoids liver toxicity and is amenable for capsid engineering and vector retargeting
Q36718570A novel adenovirus vector for easy cloning in the E3 region downstream of the CMV promoter
Q33251081A novel and simple method for construction of recombinant adenoviruses
Q35641856A novel and simple method for rapid generation of recombinant porcine adenoviral vectors for transgene expression
Q28727030A novel chimpanzee adenovirus vector with low human seroprevalence: improved systems for vector derivation and comparative immunogenicity
Q24682328A simplified system for generating recombinant adenoviruses
Q33520212A strategy for adenovirus vector targeting with a secreted single chain antibody
Q30928323A tail-anchored myotonic dystrophy protein kinase isoform induces perinuclear clustering of mitochondria, autophagy, and apoptosis
Q31104314AcMNPV core gene ac109 is required for budded virion transport to the nucleus and for occlusion of viral progeny
Q40815010Activation of adenoviral gene expression by protein IX is not required for efficient virus replication
Q40175603Ad 2.0: a novel recombineering platform for high-throughput generation of tailored adenoviruses
Q33305143Adeno-associated viral vectors engineered for macrolide-adjustable transgene expression in mammalian cells and mice
Q39596327Adeno-associated virus type 2 protein interactions: formation of pre-encapsidation complexes
Q40632527Adenoviral Transgene Ubiquitination Enhances Mouse Immunization and Class I Presentation by Human Dendritic Cells
Q36935134Adenoviral vectors for gene therapy
Q41866410Adenovirus IVa2 protein binds ATP.
Q30375982Adenovirus as a carrier for the development of influenza virus-free avian influenza vaccines.
Q24293503Adenovirus gene transfer to amelogenesis imperfecta ameloblast-like cells
Q39707314Adenovirus late-phase infection is controlled by a novel L4 promoter.
Q34700810Adenovirus particles that display the Plasmodium falciparum circumsporozoite protein NANP repeat induce sporozoite-neutralizing antibodies in mice
Q43163170Adenovirus serotype 5 L4-22K and L4-33K proteins have distinct functions in regulating late gene expression.
Q36323991Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake
Q27317286Adenovirus-Mediated Expression of the p14 Fusion-Associated Small Transmembrane Protein Promotes Cancer Cell Fusion and Apoptosis In Vitro but Does Not Provide Therapeutic Efficacy in a Xenograft Mouse Model of Cancer
Q41699782Adenovirus-Mediated Gene Delivery: Potential Applications for Gene and Cell-Based Therapies in the New Era of Personalized Medicine
Q34041940Adenoviruses as vectors for delivering vaccines to mucosal surfaces
Q64905542An Oncolytic Adenovirus Vector Expressing p14 FAST Protein Induces Widespread Syncytium Formation and Reduces Tumor Growth Rate In Vivo.
Q34577155An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer
Q33786008An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism
Q37945220An update on canine adenovirus type 2 and its vectors
Q39685068Antibody-mediated targeted gene transfer to NMDA NR1-containing neurons in rat neocortex by helper virus-free HSV-1 vector particles containing a chimeric HSV-1 glycoprotein C-staphylococcus A protein
Q33700607Association of Tat with Promoters of PTEN and PP2A Subunits Is Key to Transcriptional Activation of Apoptotic Pathways in HIV-Infected CD4+ T Cells
Q21296738Bacterial artificial chromosome mutagenesis using recombineering
Q38286656Bovine adenovirus-3 as a vaccine delivery vehicle.
Q36699786Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection
Q90344595Canine Adenovirus 2: A Natural Choice for Brain Circuit Dissection
Q34926393Canine adenovirus type 2 vector generation via I-Sce1-mediated intracellular genome release
Q39588767Canine adenovirus vectors: an alternative for adenovirus-mediated gene transfer
Q39835775Cell lines from the Egyptian fruit bat are permissive for modified vaccinia Ankara
Q37382109Cellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors
Q42734186Characterization of Empty adenovirus particles assembled in the absence of a functional adenovirus IVa2 protein
Q39577664Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob
Q34322336Characterization of human adenovirus 35 and derivation of complex vectors
Q34437167Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge
Q35279932Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer
Q27472916Comparative vaccine studies in HLA-A2.1-transgenic mice reveal a clustered organization of epitopes presented in hepatitis C virus natural infection
Q35180550Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector.
Q39879201Conditional repression of the E2 transcription unit in E1-E3-deleted adenovirus vectors is correlated with a strong reduction in viral DNA replication and late gene expression in vitro
Q39151214Conditionally replicative adenoviral vectors for imaging the effect of chemotherapy on pancreatic cancer cells
Q35206396Conserved arginines of bovine adenovirus-3 33K protein are important for transportin-3 mediated transport and virus replication
Q40794442Construction of adenoviral vectors
Q39878424Construction of adenovirus vectors through Cre-lox recombination
Q33851984Construction of avian adenovirus CELO recombinants in cosmids
Q36890695Construction, Rescue, and Characterization of Vectors Derived from Ovine Atadenovirus
Q33983262Control of gene expression by the retinoic acid-related orphan receptor alpha in HepG2 human hepatoma cells
Q35810067Cystic fibrosis transmembrane conductance regulator does not affect neutrophil migration across cystic fibrosis airway epithelial monolayers
Q40722127Deletion of penton RGD motifs affects the efficiency of both the internalization and the endosome escape of viral particles containing adenovirus serotype 5 or 35 fiber knobs
Q39585255Dependence of adenovirus infectivity on length of the fiber shaft domain
Q34280138Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation
Q40441928Development and assessment of human adenovirus type 11 as a gene transfer vector
Q39683618Development and characterization of bovine x human hybrid cell lines that efficiently support the replication of both wild-type bovine and human adenoviruses and those with E1 deleted
Q27676519Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters
Q34120794Development of a targeted gene vector platform based on simian adenovirus serotype 24.
Q47558190Development of novel vaccine vectors: Chimpanzee adenoviral vectors
Q33344440Directed evolution generates a novel oncolytic virus for the treatment of colon cancer
Q34976257Distinct Roles of the Adenovirus E4 ORF3 Protein in Viral DNA Replication and Inhibition of Genome Concatenation
Q24293334Divergent mitochondrial and endoplasmic reticulum association of DMPK splice isoforms depends on unique sequence arrangements in tail anchors.
Q42917817Dominant regulation of interendothelial cell gap formation by calcium-inhibited type 6 adenylyl cyclase
Q36854089E1A and E1B proteins inhibit inflammation induced by adenovirus
Q35904034E2F/Rb Family Proteins Mediate Interferon Induced Repression of Adenovirus Immediate Early Transcription to Promote Persistent Viral Infection
Q64377175Effect of Relaxin Expressing Adenovirus on Scar Remodeling: A Preliminary Study
Q92748624Effect of Relaxin Expression from an Alginate Gel-Encapsulated Adenovirus on Scar Remodeling in a Pig Model
Q33770522Effective modifications for improved homologous recombination and high-efficiency generation of recombinant adenovirus-based vectors
Q24792408Efficient adenovirus-mediated gene transfer into primary T cells and thymocytes in a new coxsackie/adenovirus receptor transgenic model
Q32082734Efficient directional cloning of recombinant adenovirus vectors using DNA-protein complex
Q33799667Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vector
Q33252754Efficient generation of double heterologous promoter controlled oncolytic adenovirus vectors by a single homologous recombination step in Escherichia coli
Q36438269Efficient generation of recombinant adenoviral vectors by Cre-lox recombination in vitro
Q38662649Elastic force restricts growth of the murine utricle.
Q39580980Encapsidation of viral DNA requires the adenovirus L1 52/55-kilodalton protein
Q34979041Endospanins regulate a postinternalization step of the leptin receptor endocytic pathway
Q39597930Episomal segregation of the adenovirus enhancer sequence by conditional genome rearrangement abrogates late viral gene expression
Q35122385Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.
Q37369645Exploiting features of adenovirus replication to support mammalian kinase production
Q28344283Expression of 5-lipoxygenase in pulmonary artery endothelial cells
Q34445566Expression of VP7, a Bluetongue virus group specific antigen by viral vectors: analysis of the induced immune responses and evaluation of protective potential in sheep
Q39549150Fiberless recombinant adenoviruses: virus maturation and infectivity in the absence of fiber.
Q33844598Functional analysis of adenovirus protein IX identifies domains involved in capsid stability, transcriptional activity, and nuclear reorganization
Q43157946Gene transfer into neural cells in vitro using adenoviral vectors
Q31002814General strategy for broadening adenovirus tropism.
Q36276709Generation of an adenovirus-parvovirus chimera with enhanced oncolytic potential.
Q33779555Generation of cell lines to complement adenovirus vectors using recombination-mediated cassette exchange.
Q39606358Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber
Q39602429Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin
Q40012083Genetically targeted adenovirus vector directed to CD40-expressing cells
Q39960246Genome size and structure determine efficiency of postinternalization steps and gene transfer of capsid-modified adenovirus vectors in a cell-type-specific manner
Q39437315Getting genetic access to natural adenovirus genomes to explore vector diversity
Q33678960HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells.
Q40769181Helper virus-free HSV-1 vectors packaged both in the presence of VSV G protein and in the absence of HSV-1 glycoprotein B support gene transfer into neurons in the rat striatum
Q40883683Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo
Q39601760Hepatitis B virus (HBV) virion and covalently closed circular DNA formation in primary tupaia hepatocytes and human hepatoma cell lines upon HBV genome transduction with replication-defective adenovirus vectors
Q33740415Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting
Q40632778High throughput creation of recombinant adenovirus vectors by direct cloning, green-white selection and I-Sce I-mediated rescue of circular adenovirus plasmids in 293 cells
Q30815080High-efficiency system for the construction of adenovirus vectors and its application to the generation of representative adenovirus-based cDNA expression libraries
Q64374767Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Suppresses Human Adenovirus Gene Expression and Replication
Q47398490Human adenovirus infection causes the cellular MKRN1 E3 ubiquitin ligase degradation involving the viral core protein pVII.
Q38682348Human adenovirus type 5 vectors deleted of early region 1 (E1) undergo limited expression of early replicative E2 proteins and DNA replication in non-permissive cells.
Q35914497Human and simian immunodeficiency virus-mediated upregulation of the apoptotic factor TRAIL occurs in antigen-presenting cells from AIDS-susceptible but not from AIDS-resistant species
Q33763110Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase
Q34286779Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2
Q24673603Identification of SRPK1 and SRPK2 as the major cellular protein kinases phosphorylating hepatitis B virus core protein
Q64377365Identification of cis-acting sequences required for selective packaging of bovine adenovirus type 3 DNA
Q39529490Identification of the hemolysis-associated protein 1 as a cross-protective immunogen of Leptospira interrogans by adenovirus-mediated vaccination
Q56989931Immunogenicity of adenovirus-vector vaccine targeting hepatitis B virus: non-clinical safety assessment in non-human primates
Q39752863Improved potency and selectivity of an oncolytic E1ACR2 and E1B19K deleted adenoviral mutant in prostate and pancreatic cancers
Q33782356In vitro and in vivo biology of recombinant adenovirus vectors with E1, E1/E2A, or E1/E4 deleted.
Q39946508In vitro and in vivo properties of adenovirus vectors with increased affinity to CD46
Q37456186In vitro dynamic visualization analysis of fluorescently labeled minor capsid protein IX and core protein V by simultaneous detection
Q40336666In vitro gene targeting in human hepatoblastoma.
Q45869133Infectivity enhanced, cyclooxygenase-2 promoter-based conditionally replicative adenovirus for pancreatic cancer
Q34347524Intact microtubules support adenovirus and herpes simplex virus infections
Q33854633Intratumoral spread and increased efficacy of a p53-VP22 fusion protein expressed by a recombinant adenovirus
Q24316352LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice
Q33755007Linked tumor-selective virus replication and transgene expression from E3-containing oncolytic adenoviruses
Q33804926Liver-specific alpha 2 interferon gene expression results in protection from induced hepatitis
Q42010270Localization of the N-terminus of minor coat protein IIIa in the adenovirus capsid.
Q64374981Long-term correction of hemophilia B using adenoviral delivery of CRISPR/Cas9
Q28609619Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells
Q26750912Methods and clinical development of adenovirus-vectored vaccines against mucosal pathogens
Q33850826Microtubule-independent motility and nuclear targeting of adenoviruses with fluorescently labeled genomes
Q33697866MnSOD upregulation induces autophagic programmed cell death in senescent keratinocytes
Q40055106Modification of adenovirus capsid with a designed protein ligand yields a gene vector targeted to a major molecular marker of cancer
Q28365607Modifications of eukaryotic initiation factor 4F (eIF4F) in adult cardiocytes by adenoviral gene transfer: differential effects on eIF4F activity and total protein synthesis rates
Q64068506Modified MHC Class II-Associated Invariant Chain Induces Increased Antibody Responses against Antigens after Adenoviral Vaccination
Q34362038Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein
Q39549432Mutational analysis of the avian adenovirus CELO, which provides a basis for gene delivery vectors.
Q33855218Mutations to bid cleavage sites protect hepatocytes from apoptosis after ischemia/reperfusion injury
Q34187531Noninvasive monitoring of mRFP1- and mCherry-labeled oncolytic adenoviruses in an orthotopic breast cancer model by spectral imaging
Q40408474Notch3 is required for arterial identity and maturation of vascular smooth muscle cells
Q37145300Novel immunocompetent murine tumor model for evaluation of conditionally replication-competent (oncolytic) murine adenoviral vectors
Q51849210Oncolytic Adenoviruses in Cancer Treatment.
Q39882822Oncolytic adenoviral mutants with E1B19K gene deletions enhance gemcitabine-induced apoptosis in pancreatic carcinoma cells and anti-tumor efficacy in vivo
Q40842998Optimization of bovine coronavirus hemagglutinin-estrase glycoprotein expression in E3 deleted bovine adenovirus-3.
Q34996749Optimization of the helper-dependent adenovirus system for production and potency in vivo
Q27304840Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability.
Q33817933Ovine adenovirus vectors overcome preexisting humoral immunity against human adenoviruses in vivo
Q30476274PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a
Q42204796Pancreatic transduction by helper-dependent adenoviral vectors via intraductal delivery.
Q36049440Peptide targeting of adenoviral vectors to augment tumor gene transfer
Q43632080Preparation of two types p53 recombinant adenovirus and quantitative exogenous expression of green fluorescence protein by flow cytometry
Q37167960Preventing spontaneous genetic rearrangements in the transgene cassettes of adenovirus vectors
Q33640963Production and purification of non replicative canine adenovirus type 2 derived vectors
Q30226988Production of adenovirus vectors and their use as a delivery system for influenza vaccines
Q33517124Protective role of R-spondin1, an intestinal stem cell growth factor, against radiation-induced gastrointestinal syndrome in mice
Q27473469Protein-Protein Interactions between Hepatitis C Virus Nonstructural Proteins
Q36791710RGD peptide-modified adenovirus expressing hepatocyte growth factor and X-linked inhibitor of apoptosis improves islet transplantation.
Q35942431Rab11A controls the biogenesis of Birbeck granules by regulating Langerin recycling and stability
Q39683249Rapid construction of adenoviral vectors by lambda phage genetics
Q45874251Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent.
Q36949857Recombinant adenovirus as a methodology for exploration of physiologic functions of growth factor pathways
Q38961427Recombinant bovine adenovirus-3 co-expressing bovine respiratory syncytial virus glycoprotein G and truncated glycoprotein gD of bovine herpesvirus-1 induce immune responses in cotton rats
Q30957737Recombinant human adenovirus: targeting to the human transferrin receptor improves gene transfer to brain microcapillary endothelium
Q33819873Regulation of adenovirus-mediated transgene expression by the viral E4 gene products: requirement for E4 ORF3.
Q24304483Regulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formation
Q40390936Regulation of neurite outgrowth in N1E-115 cells through PDZ-mediated recruitment of diacylglycerol kinase zeta
Q33822773Replication-defective bovine adenovirus type 3 as an expression vector
Q39732556Requirement of the adenovirus IVa2 protein for virus assembly
Q34699410Retargeting adenoviral vectors to improve gene transfer into tumors
Q34120709Retargeting of adenovirus vectors through genetic fusion of a single-chain or single-domain antibody to capsid protein IX.
Q41864063Role for the L1-52/55K protein in the serotype specificity of adenovirus DNA packaging
Q39604759Role for the adenovirus IVa2 protein in packaging of viral DNA
Q64374656Safety and Immunogenicity of a Novel Recombinant Simian Adenovirus ChAdOx2 as a Vectored Vaccine
Q55513326Seamless assembly of recombinant adenoviral genomes from high-copy plasmids.
Q35170422Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.
Q36775480Soluble receptor-mediated selective inhibition of VEGFR and PDGFRbeta signaling during physiologic and tumor angiogenesis
Q58866812Strategy of Human Cytomegalovirus To Escape Interferon Beta-Induced APOBEC3G Editing Activity
Q35695799Successful inhibition of intracranial human glioblastoma multiforme xenograft growth via systemic adenoviral delivery of soluble endostatin and soluble vascular endothelial growth factor receptor-2: laboratory investigation
Q39601191Successful interference with cellular immune responses to immunogenic proteins encoded by recombinant viral vectors
Q35153978Syndecan 4 is involved in mediating HCV entry through interaction with lipoviral particle-associated apolipoprotein E
Q37693810T cells induced by recombinant chimpanzee adenovirus alone and in prime-boost regimens decrease chimeric EcoHIV/NDK challenge virus load
Q41646089TG1050, an immunotherapeutic to treat chronic hepatitis B, induces robust T cells and exerts an antiviral effect in HBV-persistent mice
Q40402866Targeted gene transfer to nigrostriatal neurons in the rat brain by helper virus-free HSV-1 vector particles that contain either a chimeric HSV-1 glycoprotein C-GDNF or a gC-BDNF protein
Q52431082Targeted in vivo knock-in of human alpha-1-antitrypsin cDNA using adenoviral delivery of CRISPR/Cas9.
Q37227135Targeting of adenovirus serotype 5 pseudotyped with short fiber from serotype 41 to c-erbB2-positive cells using bispecific single-chain diabody
Q34226547Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge
Q36850837Tat engagement of p38 MAP kinase and IRF7 pathways leads to activation of interferon-stimulated genes in antigen-presenting cells.
Q37150920Tat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes
Q42577485The C-terminal domains of adenovirus serotype 5 protein IX assemble into an antiparallel structure on the facets of the capsid.
Q38880684The Human Adenovirus Type 5 L4 Promoter Is Negatively Regulated by TFII-I and L4-33K.
Q47269122The Human Cytomegalovirus Tegument Protein pp65 (pUL83) Dampens Type I Interferon Production by Inactivating the DNA Sensor cGAS without Affecting STING.
Q34717916The L4 22-kilodalton protein plays a role in packaging of the adenovirus genome
Q28574430The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes
Q30415541The adenovirus L4-22K protein has distinct functions in the posttranscriptional regulation of gene expression and encapsidation of the viral genome
Q30421658The adenovirus L4-22K protein is multifunctional and is an integral component of crucial aspects of infection
Q30416104The adenovirus L4-33K protein regulates both late gene expression patterns and viral DNA packaging
Q33853916The adenovirus major core protein VII is dispensable for virion assembly but is essential for lytic infection
Q39106880The human adenovirus 5 L4 promoter is activated by cellular stress response protein p53.
Q33201422The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3
Q27486151The major form of hepatitis C virus alternate reading frame protein is suppressed by core protein expression
Q41895997The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic.
Q40372177The nucleotide sequence and a first generation gene transfer vector of species B human adenovirus serotype 3.
Q24290927The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response
Q33730717Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL.
Q36640360Therapeutic efficacy of Tyro3, Axl, and Mer tyrosine kinase agonists in collagen-induced arthritis
Q37127836Therapeutic efficacy of an oncolytic adenovirus containing RGD ligand in minor capsid protein IX and Fiber, Δ24DoubleRGD, in an ovarian cancer model
Q37270929Therapeutic vaccines for non-Hodgkin B-cell lymphoma.
Q36387903Thermostability/infectivity defect caused by deletion of the core protein V gene in human adenovirus type 5 is rescued by thermo-selectable mutations in the core protein X precursor
Q33859402Transduction and oncolytic profile of a potent replication-competent adenovirus 11p vector (RCAd11pGFP) in colon carcinoma cells
Q41900379Transposon-assisted cloning and traceless mutagenesis of adenoviruses: Development of a novel vector based on species D.
Q39505379Treatment of pancreatic cancer with an oncolytic adenovirus expressing interleukin-12 in Syrian hamsters.
Q39561803Truncating the i-leader open reading frame enhances release of human adenovirus type 5 in glioma cells
Q35162649VEGF is essential for the growth and migration of human hepatocellular carcinoma cells
Q36387929Vascular endothelial growth factor promoter-based conditionally replicative adenoviruses for pan-carcinoma application
Q33581711Viral DNA synthesis-dependent titration of a cellular repressor activates transcription of the human adenovirus type 2 IVa2 gene

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