Annemarie Honegger

researcher

Annemarie Honegger is …
instance of (P31):
humanQ5

External links are
P496ORCID iD0000-0002-3378-3967

P69educated atUniversity of ZurichQ206702
P108employerUniversity of ZurichQ206702
P734family nameHoneggerQ1626822
HoneggerQ1626822
HoneggerQ1626822
P735given name???Q18091447
???Q18091447
P106occupationresearcherQ1650915
P21sex or genderfemaleQ6581072

Reverse relations

author (P50)
Q41148860A combined NMR and computational approach to investigate peptide binding to a designed Armadillo repeat protein
Q33224274A mutation designed to alter crystal packing permits structural analysis of a tight-binding fluorescein-scFv complex
Q54572063A natural antibody missing a cysteine in VH: consequences for thermodynamic stability and folding.
Q41091475A point mutation at the ATP-binding site of the EGF-receptor abolishes signal transduction
Q24310428A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1
Q47547452Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control.
Q36889497Affinity and folding properties both influence the selection of antibodies with the selectively infective phage (SIP) methodology.
Q42069677Aggregation-induced activation of the epidermal growth factor receptor protein tyrosine kinase
Q28626012All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. Identification of a novel site in EGF receptor
Q56896879Antibody scFv fragments without disulfide bonds made by molecular evolution
Q41092861Biological activities of EGF-receptor mutants with individually altered autophosphorylation sites
Q31122335Biophysical properties of human antibody variable domains
Q39204394CD19-specific triplebody SPM-1 engages NK and γδ T cells for rapid and efficient lysis of malignant B-lymphoid cells
Q42146689Chemical modification of peptides by hydrazine
Q41821194Comparison of buffers and detection systems for high-pressure liquid chromatography of peptide mixtures
Q27728111Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition
Q57840015Correlation between in Vitro Stability and in Vivo Performance of Anti-GCN4 Intrabodies as Cytoplasmic Inhibitors
Q34292126Critical features for biosynthesis, stability, and functionality of a G protein-coupled receptor uncovered by all-versus-all mutations
Q27639109Crystal structure of the anti-His tag antibody 3D5 single-chain fragment complexed to its antigen
Q40819546Cytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors
Q27704252DARPin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
Q34036904DARPins recognizing the tumor-associated antigen EpCAM selected by phage and ribosome display and engineered for multivalency
Q27676519Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters
Q30845963Direct in vivo screening of intrabody libraries constructed on a highly stable single-chain framework
Q52525981Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.
Q46380702Domain interactions in the Fab fragment: a comparative evaluation of the single-chain Fv and Fab format engineered with variable domains of different stability
Q57174193Dual-targeting triplebody 33-16-123 (SPM-2) mediates effective redirected lysis of primary blasts from patients with a broad range of AML subtypes in combination with natural killer cells
Q38926881Efficient cell-specific uptake of binding proteins into the cytoplasm through engineered modular transport systems
Q112645163Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action
Q37028978Engineering antibodies for stability and efficient folding.
Q42025518Evidence for epidermal growth factor (EGF)-induced intermolecular autophosphorylation of the EGF receptors in living cells
Q41730272Expression of a human insulin-like growth factor II cDNA in NIH-3T3 cells
Q57840110Folding Nuclei of the scFv Fragment of an Antibody†
Q41739529Generation of recombinant cytoplasmic domain of epidermal growth factor receptor with intrinsic protein tyrosine kinase activity
Q56896411High thermal stability is essential for tumor targeting of antibody fragments: engineering of a humanized anti-epithelial glycoprotein-2 (epithelial cell adhesion molecule) single-chain Fv fragment
Q27620017Insight into odorant perception: the crystal structure and binding characteristics of antibody fragments directed against the musk odorant traseolide
Q58450636Insulin-like growth factors I and II in fetal and adult bovine serum. Purification, primary structures, and immunological cross-reactivities
Q27315979Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS-p110 crosstalk
Q41092869Kinetic parameters of the protein tyrosine kinase activity of EGF-receptor mutants with individually altered autophosphorylation sites
Q41846083Metabolic effects induced by epidermal growth factor (EGF) in cells expressing EGF receptor mutants
Q42806503Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing
Q30195382Presence of SH2 domains of phospholipase C gamma 1 enhances substrate phosphorylation by increasing the affinity toward the epidermal growth factor receptor
Q38906090Receptor-targeted lentiviral vectors are exceptionally sensitive toward the biophysical properties of the displayed single-chain Fv.
Q32000846Reproducing the natural evolution of protein structural features with the selectively infective phage (SIP) technology. The kink in the first strand of antibody kappa domains.
Q41330278Rigidly connected multispecific artificial binders with adjustable geometries.
Q30810332Selection for improved protein stability by phage display.
Q27632404Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries
Q42832582Separate endocytic pathways of kinase-defective and -active EGF receptor mutants expressed in same cells
Q58450633Signal Transduction by Epidermal Growth Factor Receptor
Q56897080Specific detection of his-tagged proteins with recombinant anti-His tag scFv-phosphatase or scFv-phage fusions
Q35863490Stability improvement of antibodies for extracellular and intracellular applications: CDR grafting to stable frameworks and structure-based framework engineering
Q40005721Stabilization and humanization of a single-chain Fv antibody fragment specific for human lymphocyte antigen CD19 by designed point mutations and CDR-grafting onto a human framework
Q27686917Structural basis for eliciting a cytotoxic effect in HER2-overexpressing cancer cells via binding to the extracellular domain of HER2
Q30885937Structure-based improvement of the biophysical properties of immunoglobulin VH domains with a generalizable approach
Q45881214T-cell receptor gene transfer exclusively to human CD8(+) cells enhances tumor cell killing
Q42173081The behaviour of peptides on reverse-phase supports during high-pressure liquid chromatography
Q39828671The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies.
Q27632417The importance of framework residues H6, H7 and H10 in antibody heavy chains: experimental evidence for a new structural subclassification of antibody V(H) domains
Q43633084The influence of the buried glutamine or glutamate residue in position 6 on the structure of immunoglobulin variable domains
Q46167685The influence of the framework core residues on the biophysical properties of immunoglobulin heavy chain variable domains
Q57840080The nature of antibody heavy chain residue H6 strongly influences the stability of a VH domain lacking the disulfide bridge
Q31142518Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library.
Q57840011Yet Another Numbering Scheme for Immunoglobulin Variable Domains: An Automatic Modeling and Analysis Tool

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