review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1048329674 |
P356 | DOI | 10.1186/1478-811X-6-11 |
P932 | PMC publication ID | 2647539 |
P698 | PubMed publication ID | 19114018 |
P50 | author | Ottmar Janssen | Q51115166 |
P2093 | author name string | Matthias Voss | |
Marcus Lettau | |||
Maren Paulsen | |||
P2860 | cites work | A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b | Q24296642 |
SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production | Q24296666 | ||
Regulation of FasL expression: a SH3 domain containing protein family involved in the lysosomal association of FasL | Q24297477 | ||
The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells | Q24308074 | ||
Plasminogen activator inhibitor-1 protects endothelial cells from FasL-mediated apoptosis | Q24319106 | ||
A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells | Q24338698 | ||
Receptor downregulation and multivesicular-body sorting | Q28131720 | ||
Lipid rafts and signal transduction | Q28131735 | ||
CD95's deadly mission in the immune system | Q28142072 | ||
The TNF and TNF receptor superfamilies: integrating mammalian biology | Q28203717 | ||
Multiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factor | Q28210406 | ||
Identification of interaction partners of the cytosolic polyproline region of CD95 ligand (CD178) | Q28218575 | ||
Characterization of Fas (Apo-1, CD95)-Fas ligand interaction | Q28244083 | ||
A new class of reverse signaling costimulators belongs to the TNF family | Q28249377 | ||
Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family | Q28285445 | ||
Interaction of peptides derived from the Fas ligand with the Fyn-SH3 domain | Q28291501 | ||
The ADAM metalloproteinases | Q28292696 | ||
Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy | Q28303181 | ||
ADAMs: key components in EGFR signalling and development | Q28305519 | ||
Notch signalling: a simple pathway becomes complex | Q29555851 | ||
The Fas death factor | Q29620461 | ||
Signal-dependent membrane protein trafficking in the endocytic pathway | Q29622948 | ||
Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction | Q30014849 | ||
Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes | Q30157452 | ||
The adaptor protein Grb2 regulates cell surface Fas ligand in Schwann cells. | Q30157514 | ||
The cytoplasmic domain of Fas ligand costimulates TCR signals | Q30159720 | ||
Fas ligand is localized to membrane rafts, where it displays increased cell death-inducing activity | Q30160067 | ||
The Nck family of adapter proteins: regulators of actin cytoskeleton | Q30165392 | ||
Fas ligand is targeted to secretory lysosomes via a proline-rich domain in its cytoplasmic tail. | Q30167917 | ||
Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation. | Q30336360 | ||
Binding of the intracellular Fas ligand (FasL) domain to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL. | Q33289418 | ||
The Fas counterattack: cancer as a site of immune privilege | Q33542332 | ||
Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding. | Q33752819 | ||
Fas ligand-induced apoptosis | Q33847658 | ||
ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation. | Q33878896 | ||
A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling' | Q33890754 | ||
The molecular architecture of the TNF superfamily | Q34109796 | ||
PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor | Q34227481 | ||
Tumor counterattack: fact or fiction? | Q34418305 | ||
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex | Q34472898 | ||
Secretory lysosomes | Q34522863 | ||
The adaptor protein Nck interacts with Fas ligand: Guiding the death factor to the cytotoxic immunological synapse | Q34596132 | ||
Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas | Q34792019 | ||
Non-apoptotic Fas signaling. | Q35027104 | ||
The ADAMs family of metalloproteases: multidomain proteins with multiple functions | Q35039313 | ||
Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides | Q35057311 | ||
The CD95(APO-1/Fas) DISC and beyond | Q35091401 | ||
Signaling and transcriptional control of Fas ligand gene expression. | Q35091405 | ||
Delivering the kiss of death | Q35116674 | ||
Activation-induced cell death in T cells | Q35129715 | ||
CD95 ligand--death factor and costimulatory molecule? | Q35190128 | ||
Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system | Q35902539 | ||
Induction of tolerance using Fas ligand: a double-edged immunomodulator | Q35918998 | ||
Considering Fas ligand as a target for therapy | Q36066300 | ||
Shedding light on ADAM metalloproteinases | Q36159565 | ||
Metalloproteinase-mediated release of human Fas ligand | Q36365559 | ||
Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. | Q36370300 | ||
Maximal proliferation of cytotoxic T lymphocytes requires reverse signaling through Fas ligand | Q36381058 | ||
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity | Q36400613 | ||
Emerging roles for ectodomain shedding in the regulation of inflammatory responses | Q36432148 | ||
Breaking up the tie: disintegrin-like metalloproteinases as regulators of cell migration in inflammation and invasion. | Q36454471 | ||
How T lymphocytes switch between life and death | Q36515075 | ||
Pombe Cdc15 homology proteins: regulators of membrane dynamics and the actin cytoskeleton | Q36639196 | ||
Secretory lysosomes and their cargo in T and NK cells | Q36650422 | ||
Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions | Q36734210 | ||
How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? | Q36879036 | ||
CD8 T cells utilize TRAIL to control influenza virus infection | Q37029404 | ||
Clipping, shedding and RIPping keep immunity on cue. | Q37053286 | ||
Storage, expression and function of Fas ligand, the key death factor of immune cells. | Q37232916 | ||
Death receptor Fas (CD95) signaling in the central nervous system: tuning neuroplasticity? | Q37233845 | ||
2-D DIGE analyses of enriched secretory lysosomes reveal heterogeneous profiles of functionally relevant proteins in leukemic and activated human NK cells | Q39957412 | ||
Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts | Q40342735 | ||
Fas ligand (CD178) cytoplasmic tail is a positive regulator of Fas ligand-mediated cytotoxicity | Q40437985 | ||
Asparagine-linked oligosaccharides protect Lamp-1 and Lamp-2 from intracellular proteolysis | Q40923003 | ||
Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells | Q40981770 | ||
Separate domains of the human fas ligand dictate self-association and receptor binding | Q41070378 | ||
Downregulation of Fas ligand by shedding | Q41071790 | ||
ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling | Q41107179 | ||
Regulation of cell surface APO-1/Fas (CD95) ligand expression by metalloproteases | Q41321495 | ||
The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability | Q41839673 | ||
CTLs contain and use intracellular stores of FasL distinct from cytolytic granules | Q42825924 | ||
Identification of novel matrix metalloproteinase-7 (matrilysin) cleavage sites in murine and human Fas ligand | Q44237377 | ||
Receptor-like properties of the 26 kDa transmembrane form of TNF. | Q52544124 | ||
Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells. | Q53431419 | ||
ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death. | Q53572097 | ||
Sorting of Fas ligand to secretory lysosomes is regulated by mono-ubiquitylation and phosphorylation. | Q53582778 | ||
Comparative molecular modelling of the Fas-ligand and other members of the TNF family | Q57075447 | ||
The CD95 Receptor: Apoptosis Revisited | Q62734296 | ||
Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege | Q63408406 | ||
Fas ligand costimulates the in vivo proliferation of CD8+ T cells | Q73163098 | ||
Newly discovered role for Fas ligand in the cell-cycle arrest of CD4+ T cells | Q77658689 | ||
Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles | Q78025377 | ||
Analysis of Fas-ligand interactions using a molecular model of the receptor-ligand interface | Q78057597 | ||
Cutting edge: two distinct motifs within the Fas ligand tail regulate Fas ligand-mediated costimulation | Q81464205 | ||
P304 | page(s) | 11 | |
P577 | publication date | 2008-12-29 | |
P1433 | published in | Cell Communication and Signaling | Q1254390 |
P1476 | title | Posttranslational regulation of Fas ligand function | |
P478 | volume | 6 |
Q50252931 | Apoptosis of rat ovarian granulosa cells by 2,5-hexanedione in vitro and its relevant gene expression |
Q52655011 | Association analysis of FAS-670A/G and FASL-844C/T polymorphisms with risk of generalized aggressive periodontitis disease. |
Q42089284 | CD59 signaling and membrane pores drive Syk-dependent erythrocyte necroptosis |
Q30009520 | Differential protein-protein interactions of full length human FasL and FasL fragments generated by proteolysis |
Q35018592 | Differential surface expression of ADAM10 and ADAM17 on human T lymphocytes and tumor cells |
Q39791226 | Effector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells |
Q33488348 | Enrichment and analysis of secretory lysosomes from lymphocyte populations |
Q39236160 | Fas ligand plays an important role for the production of pro-inflammatory cytokines in intervertebral disc nucleus pulposus cells |
Q35051748 | Herpes simplex virus type 1-induced FasL expression in human monocytic cells and its implications for cell death, viral replication, and immune evasion |
Q24322679 | Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening |
Q48191024 | Impairment of Fas-ligand-caveolin-1 interaction inhibits Fas-ligand translocation to rafts and Fas-ligand-induced cell death. |
Q47171898 | Mesenchymal Stem Cells Secretory Responses: Senescence Messaging Secretome and Immunomodulation Perspective. |
Q41894662 | Pro- and anti-apoptotic CD95 signaling in T cells |
Q92643838 | miR-21 induces endothelial progenitor cells proliferation and angiogenesis via targeting FASLG and is a potential prognostic marker in deep venous thrombosis |
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