Fas ligand-induced apoptosis

scientific article

Fas ligand-induced apoptosis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1146/ANNUREV.GENET.33.1.29
P698PubMed publication ID10690403

P2093author name stringNagata S
P2860cites workLethal effect of the anti-Fas antibody in miceQ36696599
P921main subjectapoptotic processQ14599311
P304page(s)29-55
P577publication date1999-01-01
P1433published inAnnual Review of GeneticsQ567358
P1476titleFas ligand-induced apoptosis
P478volume33

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cites work (P2860)
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Q24602589CD95 promotes tumour growth
Q93072519CD95-ligand contributes to abdominal aortic aneurysm progression by modulating inflammation
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Q28575019Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis
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Q38602578Cathepsin-B and cathepsin-L expression levels do not correlate with sensitivity of tumour cells to TNF-alpha-mediated apoptosis.
Q34148152Cell receptors and cell signalling
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Q40504973Cell-to-cell contact influences proliferative marker expression and apoptosis in MIN6 cells grown in islet-like structures
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Q30357159Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes
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Q55385725Cisplatin-induced oxidative stress stimulates renal Fas ligand shedding.
Q42202353Combination of bladder cancer-specific oncolytic adenovirus gene therapy with cisplatin on bladder cancer in vitro
Q44292870Combined action of ERK and NF kappa B mediates the protective effect of phorbol ester on Fas-induced apoptosis in Jurkat cells
Q55441897Confirmation of covalently-linked structure and cell-death inducing activity in site-specific chemical conjugates of human Fas ligand extracellular domain.
Q27014934Conservation of hearing and protection of hair cells in cochlear implant patients' with residual hearing
Q36066300Considering Fas ligand as a target for therapy
Q50335898Cooperation between STAT3 and c-jun suppresses Fas transcription.
Q33748166Coupling of the cell cycle and apoptotic machineries in developing T cells
Q46425003Cutaneous antibodies from channel catfish, Ictalurus punctatus (Rafinesque), immune to Ichthyophthirius multifiliis (Ich) may induce apoptosis of Ich theronts
Q44210269Cytochrome c associated apoptosis during ATP recovery after hypoxia in neonatal rat cerebrocortical slices
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Q30009520Differential protein-protein interactions of full length human FasL and FasL fragments generated by proteolysis
Q52106896Distinct Pathways Mediate UV-Induced Apoptosis in Drosophila Embryos
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Q36820385Dual roles of intermediate filaments in apoptosis
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Q33925284Effects of Fas-ligand overexpression on alveolar type II cell growth kinetics in perinatal murine lungs
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Q58556468Elevated Soluble Fas and FasL in Cerebrospinal Fluid and Serum of Patients With Anti-N-methyl-D-aspartate Receptor Encephalitis
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Q24809567Evidence for a Novel, Caspase-8-Independent, Fas Death Domain-Mediated Apoptotic Pathway
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Q35220416Expression of Pseudomonas aeruginosa toxin ExoS effectively induces apoptosis in host cells
Q49629822Expression of miR-625 and Fas in cervical vertebral cartilage endplate
Q42910629FADD negatively regulates lipopolysaccharide signaling by impairing interleukin-1 receptor-associated kinase 1-MyD88 interaction
Q24300920FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface
Q36324207FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity
Q24294356FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies
Q33946622Fas (CD95) induces rapid, TLR4/IRAK4-dependent release of pro-inflammatory HMGB1 from macrophages
Q27484988Fas Ligand Interactions Contribute to CD8+ T-Cell-Mediated Control of West Nile Virus Infection in the Central Nervous System
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Q44109786Fas function and tumor progression: use it and lose it.
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Q34230773Fas-FasL in Hashimoto's thyroiditis
Q36734853Fas-ligand-induced apoptosis of respiratory epithelial cells causes disruption of postcanalicular alveolar development
Q24315092Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo
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Q23921015Fas/FasL pathway-mediated alveolar macrophage apoptosis involved in human silicosis
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Q61928355Genetic polymorphisms of Fas (CD95) and FasL (CD178) in human longevity: studies on centenarians
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Q44828233Granzymes in cytolytic lymphocytes--to kill a killer?
Q34312950Gray matter oligodendrocyte progenitors and neurons die caspase-3 mediated deaths subsequent to mild perinatal hypoxic/ischemic insults
Q38834715HSP70 mediates survival in apoptotic cells-Boolean network prediction and experimental validation
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Q34324015Hepatitis B virus X protein induces expression of Fas ligand gene through enhancing transcriptional activity of early growth response factor
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Q38495435Homer1 regulates the susceptibility to TRAIL.
Q24805664Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)
Q38595352Human cytomegalovirus suppresses Fas expression and function.
Q35618118Human primary immunodeficiency diseases: a perspective
Q33222947Hyperoxia-induced apoptosis and Fas/FasL expression in lung epithelial cells
Q53132557ING3 promotes UV-induced apoptosis via Fas/caspase-8 pathway in melanoma cells.
Q36769500Immune dysfunction in inflammatory bowel disease
Q42472070Immunohistochemical analysis of apoptosis-related factors in lining epithelium of radicular cysts
Q48191024Impairment of Fas-ligand-caveolin-1 interaction inhibits Fas-ligand translocation to rafts and Fas-ligand-induced cell death.
Q45109154Increased Fas-mediated apoptosis in polymorphonuclear cells from HIV-infected patients.
Q48175057Increased serum sFas and TNFalpha following isolated severe head injury in males.
Q35567208Increased serum soluble Fas after major trauma is associated with delayed neutrophil apoptosis and development of sepsis
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Q31049072Integrated mechanistic and data-driven modelling for multivariate analysis of signalling pathways
Q36984709Interactions of HIV and methamphetamine: cellular and molecular mechanisms of toxicity potentiation
Q40450424Interferon-beta-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through up-regulation of CD95 in CH31 B lymphoma cells.
Q35789350Interferon-gamma augments CD95(APO-1/Fas) and pro-caspase-8 expression and sensitizes human vascular endothelial cells to CD95-mediated apoptosis
Q36597952Intracellular signals and events activated by cytokines of the tumor necrosis factor superfamily: From simple paradigms to complex mechanisms.
Q44006259Involvement of Fas system and active caspases in apoptotic signalling in testicular germ cells of ethanol-treated rats
Q57295037Involvement of interferon-tau in the induction of apoptotic, pyroptotic, and autophagic cell death-related signaling pathways in the bovine uterine endometrium during early pregnancy
Q52928681Involvement of p38 MAPK in the Anticancer Activity of Cultivated Cordyceps militaris.
Q54473724Involvement of the apelin receptor APJ in Fas-induced liver injury.
Q40530480Keratins modulate c-Flip/extracellular signal-regulated kinase 1 and 2 antiapoptotic signaling in simple epithelial cells
Q33744850LFG-500, a newly synthesized flavonoid, induces apoptosis in human ovarian carcinoma SKOV3 cells with involvement of the reactive oxygen species-mitochondria pathway
Q27472849Lack of both Fas ligand and perforin protects from flavivirus-mediated encephalitis in mice
Q54263952Loss of BID Delays FASL-Induced Cell Death of Mouse Neutrophils and Aggravates DSS-Induced Weight Loss.
Q36371743Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells
Q41843570MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment
Q40516096Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis
Q23917334Mechanistically identified suitable biomarkers of exposure, effect, and susceptibility for silicosis and coal-worker's pneumoconiosis: A comprehensive review
Q34104019Metformin limits the adipocyte tumor-promoting effect on ovarian cancer.
Q36349878Methamphetamine-induced neuronal apoptosis involves the activation of multiple death pathways. Review
Q39420283MicroRNA miR-491-5p targeting both TP53 and Bcl-XL induces cell apoptosis in SW1990 pancreatic cancer cells through mitochondria mediated pathway.
Q37381107MicroRNAs as therapeutic targets in chemoresistance
Q34502221Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases
Q40579078Modifications and intracellular trafficking of FADD/MORT1 and caspase-8 after stimulation of T lymphocytes.
Q40628451Modulation of Fas receptor proteins and dynamin during opiate addiction and induction of opiate withdrawal in rat brain.
Q34574696Molecular flexibility can influence the stimulatory ability of receptor-ligand interactions at cell-cell junctions
Q34602976Molecular mechanism and biological functions of c-Jun N-terminal kinase signalling via the c-Jun transcription factor.
Q29617861Molecular mechanisms of caspase regulation during apoptosis
Q35010864Molecular mechanisms of cerebral ischemia-induced neuronal death.
Q36835812Molecular mechanisms of drug resistance in acute myeloid leukaemia
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Q37726689Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death
Q34276988Mutations in apoptosis genes: a pathogenetic factor for human disease
Q38227386NF-κB signaling at the crossroads of inflammation and atherogenesis: searching for new therapeutic links
Q53361179NaCS-PDMDAAC immobilized cultivation of recombinant Dictyostelium discoideum for soluble human Fas ligand production.
Q36797987Neurotoxicity of substituted amphetamines: molecular and cellular mechanisms
Q40468763New complex Ad vectors incorporating both rtTA and tTS deliver tightly regulated transgene expression both in vitro and in vivo.
Q36608654Newly established tumourigenic primary human colon cancer cell lines are sensitive to TRAIL-induced apoptosis in vitro and in vivo
Q46310301Nigerian bonny-light crude oil induces alteration in testicular stress response proteins and caspase-3 dependent apoptosis in albino wistar rats
Q23919035Nitric oxide negatively regulates Fas CD95-induced apoptosis through inhibition of ubiquitin-proteasome-mediated degradation of FLICE inhibitory protein
Q58581539Non-Structural Proteins from Human T-cell Leukemia Virus Type 1 in Cellular Membranes-Mechanisms for Viral Survivability and Proliferation
Q38295816Non-apoptotic signaling pathways activated by soluble Fas ligand in serum-starved human fibroblasts. Mitogen-activated protein kinases and NF-kappaB-dependent gene expression.
Q37763996Non-cytotoxic antiviral activities of granzymes in the context of the immune antiviral state.
Q58780993Not Only Redox: The Multifaceted Activity of Cerium Oxide Nanoparticles in Cancer Prevention and Therapy
Q28397635Novel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP protein
Q57162853Novel roles of apoptotic caspases in tumor repopulation, epigenetic reprogramming, carcinogenesis, and beyond
Q54764961Oligomerization of soluble Fas antigen induces its cytotoxicity.
Q35223578Opposite roles of FAP-1 and dynamin in the regulation of Fas (CD95) translocation to the cell surface and susceptibility to Fas ligand-mediated apoptosis
Q33665257Osteocyte apoptosis and control of bone resorption following ovariectomy in mice
Q37137450Osteocyte apoptosis controls activation of intracortical resorption in response to bone fatigue
Q35842259Osteoprotegerin Induces Apoptosis of Osteoclasts and Osteoclast Precursor Cells via the Fas/Fas Ligand Pathway
Q40748097Overexpression of the mouse Fas gene in human Hep3B hepatoma cells overcomes their resistance to Fas-mediated apoptosis
Q38094613Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis
Q42849327Parathyroid hormone(1-34)-induced apoptosis in neuronal rat PC12 cells: Implications for neurotoxicity
Q79629974Participation of the Fas and Fas ligand systems in apoptosis during atrophy of the rat submandibular glands
Q35852309Pathways of apoptotic and non-apoptotic death in tumour cells
Q53755850Pentoxifylline abrogates cardiotoxicity induced by the administration of a single high dose or multiple low doses of doxorubicin in rats.
Q46717647Peripheral blood cytotoxic lymphocyte gene transcript levels differ in patients with long-term type 1 diabetes compared to normal controls
Q23910430Phosphatidylinositol 3-kinase/Akt positively regulates fas (CD95)-mediated apoptosis in epidermal Cl41 cells
Q36070471Platelets induce apoptosis via membrane-bound FasL.
Q59117419Policing and punishment across the domains of social evolution
Q48442233Polymorphisms of fas gene: relationship with Alzheimer's disease and cognitive decline.
Q40015586Posttranslational regulation of Fas ligand function.
Q39367173Pre-existing Fas ligand (FasL) in cancer cells elicits tumor-specific protective immunity, but delayed induction of FasL expression after inoculation facilitates tumor formation
Q28831051Preparation of a functional fluorescent human Fas ligand extracellular domain derivative using a three-dimensional structure guided site-specific fluorochrome conjugation
Q26828994Primary hepatocytes and their cultures in liver apoptosis research
Q39241897Prognostic and therapeutic relevance of c-FLIP in acute myeloid leukaemia
Q34558290Protective effect of gadolinium chloride on early warm ischemia/reperfusion injury in rat bile duct during liver transplantation
Q82734451Protective role of quercetin on PCBs-induced oxidative stress and apoptosis in hippocampus of adult rats
Q46761334Protein-tyrosine phosphatase 1B deficiency protects against Fas-induced hepatic failure
Q35035050Proteinases and their inhibitors in the immune system
Q34419803Proteins attached to viral genomes are multifunctional
Q50117783Quantitative assessment of the relationship between Fas/FasL genes polymorphisms and head and neck cancer risk
Q35218738Radiosensitization of melanoma cells through combined inhibition of protein regulators of cell survival
Q28139203Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis
Q23914984Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation
Q35934180Recent developments in the transcriptional regulation of cytolytic effector cells
Q37350948Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis.
Q37369408Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins
Q38293794Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling.
Q44061475Regulation of Fas ligand expression by estrogen in normal ovary
Q35083681Relationship of acute lung inflammatory injury to Fas/FasL system
Q45713879Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T-cells
Q33752554Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma
Q30480565Requirement of biphasic calcium release from the endoplasmic reticulum for Fas-mediated apoptosis
Q35097404Retention of the arginine allele in codon 72 of the p53 gene correlates with poor apoptosis in head and neck cancer
Q46181262Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly.
Q64228473Reverse Signaling of Tumor Necrosis Factor Superfamily Proteins in Macrophages and Microglia: Superfamily Portrait in the Neuroimmune Interface
Q35955745Role of apoptosis-inducing factor, proline dehydrogenase, and NADPH oxidase in apoptosis and oxidative stress
Q44295660Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA).
Q42462244Saccharin consumption increases sperm DNA fragmentation and apoptosis in mice
Q28395683Salicylate-induced degeneration of cochlea spiral ganglion neurons-apoptosis signaling
Q47602872Serum anti-Fas antibody levels in amyotrophic lateral sclerosis
Q38075095Shortening the 'short-course' therapy- insights into host immunity may contribute to new treatment strategies for tuberculosis
Q33715752Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim
Q34341941Signal transduction by tumor necrosis factor and its relatives
Q35091405Signaling and transcriptional control of Fas ligand gene expression.
Q34563012Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas.
Q29616428Signalling pathways of the TNF superfamily: a double-edged sword
Q40721520Silica-induced apoptosis in murine macrophage: involvement of tumor necrosis factor-alpha and nuclear factor-kappaB activation.
Q42948122Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation
Q45873999Simultaneous stimulation of Fas-mediated apoptosis and blockade of costimulation prevent autoimmune diabetes in mice induced by multiple low-dose streptozotocin
Q33868706Site-specific chemical conjugation of human Fas ligand extracellular domain using trans-cyclooctene - methyltetrazine reactions
Q82133126Solid tumors "melt" from the inside after successful CD8 T cell attack
Q35555592Soluble TRAIL concentrations are raised in patients with systemic lupus erythematosus.
Q86992768Spatiotemporal changes in NFATc4 expression of retinal ganglion cells after light-induced damage
Q33770650Spermatogonial stem cells derived from infertile Wv/Wv mice self-renew in vitro and generate progeny following transplantation
Q44083043Splenocyte apoptosis in Plasmodium berghei ANKA infection: possible role of TNF-α and TGF-β.
Q36001216Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms
Q73766078Steering anti-cancer drugs away from the TRAIL
Q46384476Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand.
Q35060696Studies on the interaction between vitamin K-dependent protein S and complement regulator C4b-binding protein: localization of binding sites and identification of a possible function of the complex.
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Q35055041Subcellular-resolution delivery of a cytokine through precisely manipulated nanowires
Q97646320Superior Expansion and Cytotoxicity of Human Primary NK and CAR-NK Cells from Various Sources via Enriched Metabolic Pathways
Q40419557Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF-alpha expression
Q34567937T lymphocyte activation--an inside overview.
Q35998853T-helper cell intrinsic defects in lupus that break peripheral tolerance to nuclear autoantigens
Q24746223TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo
Q43963746TRAIL enhances thymidine kinase/ganciclovir gene therapy of neuroblastoma cells
Q37072696TRPC6 channel activation promotes neonatal glomerular mesangial cell apoptosis via calcineurin/NFAT and FasL/Fas signaling pathways.
Q45274551Targeting proliferating tumor cells via the transcriptional control of therapeutic genes
Q46970968Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis.
Q40505982The 2A2 protein of Duck hepatitis A virus type 1 induces apoptosis in primary cell culture
Q57183712The COSMIC Cancer Gene Census: describing genetic dysfunction across all human cancers
Q23917081The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation
Q36980502The Fas system confers protection against alveolar disruption in hyperoxia-exposed newborn mice
Q35056763The Fas system in the seminiferous epithelium and its possible extra-testicular role
Q43704395The Fas-FasL death receptor and PI3K pathways independently regulate monocyte homeostasis
Q39783719The IL-8 production by Streptococcal pyrogenic exotoxin B.
Q40637471The JAM-assay: optimized conditions to determine death-receptor-mediated apoptosis.
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