| scholarly article | Q13442814 |
| P2093 | author name string | Kevin Chen | |
| Zhiping Liu | |||
| Lee J Martin | |||
| P2860 | cites work | Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase | Q27731976 |
| Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis | Q28131805 | ||
| The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis | Q28142593 | ||
| Does vitamin C act as a pro-oxidant under physiological conditions? | Q28144458 | ||
| Cell death: critical control points | Q28240722 | ||
| Fas/tumor necrosis factor receptor death signaling is required for axotomy-induced death of motoneurons in vivo | Q28508506 | ||
| Noxa is a critical mediator of p53-dependent motor neuron death after nerve injury in adult mouse | Q28509111 | ||
| Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury | Q28511628 | ||
| Nitric Oxide and Superoxide Contribute to Motor Neuron Apoptosis Induced by Trophic Factor Deprivation | Q48539215 | ||
| Evidence of Increased Oxidative Damage in Both Sporadic and Familial Amyotrophic Lateral Sclerosis | Q48540035 | ||
| Injury-induced apoptosis of neurons in adult brain is mediated by p53-dependent and p53-independent pathways and requires Bax. | Q48921606 | ||
| Nitric oxide synthase 1 and nitric oxide synthase 3 protein expression is regionally and temporally regulated in fetal brain | Q48940897 | ||
| p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis | Q49157629 | ||
| Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite | Q50336019 | ||
| Trolox inhibits peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes | Q51562096 | ||
| Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. | Q52114306 | ||
| Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis. | Q52532134 | ||
| Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis | Q52535127 | ||
| ALS, SOD and peroxynitrite | Q59070047 | ||
| Ischaemic injury mediator | Q59075059 | ||
| DNA damage profiling in motor neurons: a single-cell analysis by comet assay | Q64387668 | ||
| Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death | Q72549763 | ||
| The roles of free radicals in amyotrophic lateral sclerosis: reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids | Q73263349 | ||
| Induction of neuronal and inducible nitric oxide synthase in the motoneurons of spinal cord following transient abdominal aorta occlusion in rats | Q73277774 | ||
| Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase | Q73316561 | ||
| Increased expression of neuronal nitric oxide synthase spliced variants in reactive astrocytes of amyotrophic lateral sclerosis human spinal cord | Q73853632 | ||
| iNOS and nitrotyrosine immunoreactivity in amyotrophic lateral sclerosis | Q74233498 | ||
| Survival in a transgenic model of FALS is independent of iNOS expression | Q74377449 | ||
| Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent | Q77544716 | ||
| Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis | Q77816092 | ||
| NO production during neuronal cell death can be directly assessed by a chemical reaction in vivo | Q77931309 | ||
| Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis | Q78021209 | ||
| Fas engagement induces neurite growth through ERK activation and p35 upregulation | Q78836977 | ||
| A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis | Q81078641 | ||
| Cell deaths in normal vertebrate ontogeny | Q87311819 | ||
| Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand | Q28513283 | ||
| Mechanisms of human DNA repair: an update | Q28608973 | ||
| Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation | Q29547561 | ||
| Unraveling the mechanisms involved in motor neuron degeneration in ALS | Q29619073 | ||
| Motor neurons rapidly accumulate DNA single-strand breaks after in vitro exposure to nitric oxide and peroxynitrite and in vivo axotomy | Q32160820 | ||
| Mechanisms of DNA oxidation | Q33796847 | ||
| Fas ligand-induced apoptosis | Q33847658 | ||
| Par-4: an emerging pivotal player in neuronal apoptosis and neurodegenerative disorders | Q33848300 | ||
| Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism | Q33862444 | ||
| Defying death after DNA damage. | Q34068957 | ||
| Apoptosis in amyotrophic lateral sclerosis: a review of the evidence. | Q34352949 | ||
| Comparative evaluation of synaptophysin-based methods for quantification of synapses | Q34415699 | ||
| Superoxide dismutase and the death of motoneurons in ALS. | Q34553806 | ||
| Nitric oxide and superoxide, a deadly cocktail. | Q34699675 | ||
| Prospects for antiapoptotic drug therapy of neurodegenerative diseases | Q35092261 | ||
| Protein interactions with nitric oxide synthases: controlling the right time, the right place, and the right amount of nitric oxide | Q35169824 | ||
| The "fuzzy logic" of the death-inducing signaling complex in lymphocytes | Q35577256 | ||
| Peroxynitrous acid--where is the hydroxyl radical? | Q35622917 | ||
| Programmed cell death of embryonic motoneurons triggered through the Fas death receptor | Q36316322 | ||
| p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs | Q36401199 | ||
| Principles and practice of DNA filter elution | Q37182650 | ||
| Neuronal NADPH diaphorase is a nitric oxide synthase | Q37463023 | ||
| Cell death during development of the nervous system | Q37716922 | ||
| Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus | Q38294071 | ||
| Neonatal mice lacking functional Fas death receptors are resistant to hypoxic-ischemic brain injury | Q38337014 | ||
| Inhibition of poly(ADP-RIBOSE) polymerase (PARP) by nitric oxide and reactive nitrogen oxide species | Q40612320 | ||
| Human Ogg1, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide. | Q40783678 | ||
| Overexpression of Ogg1 in mammalian cells: effects on induced and spontaneous oxidative DNA damage and mutagenesis. | Q40931923 | ||
| Expression of Nitric-Oxide Synthase (NOS) in Injured CNS Neurons as Shown by NADPH Diaphorase Histochemistry | Q41085208 | ||
| Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis | Q41179786 | ||
| Apoptosis of Retrogradely Degenerating Neurons Occurs in Association with the Accumulation of Perikaryal Mitochondria and Oxidative Damage to the Nucleus | Q42082553 | ||
| In vivo protection of a water-soluble derivative of vitamin E, Trolox, against methylmercury-intoxication in the rat. | Q43601579 | ||
| Direct nitric oxide imaging in cultured hippocampal neurons with diaminoanthraquinone and confocal microscopy | Q43670044 | ||
| Spatial nitric oxide imaging using 1,2-diaminoanthraquinone to investigate the involvement of nitric oxide in long-term potentiation in rat brain slices | Q43889108 | ||
| Immature and mature cortical neurons engage different apoptotic mechanisms involving caspase-3 and the mitogen-activated protein kinase pathway | Q44097738 | ||
| Rapid subcellular redistribution of Bax precedes caspase-3 and endonuclease activation during excitotoxic neuronal apoptosis in rat brain | Q44107197 | ||
| Inhibition of nitric oxide synthase reduces motoneuron death due to spinal root avulsion | Q45083038 | ||
| Neuronal NOS deficiency promotes apoptotic cell death of spinal cord neurons after peripheral nerve transection | Q47626323 | ||
| GDNF and BDNF alter the expression of neuronal NOS, c-Jun, and p75 and prevent motoneuron death following spinal root avulsion in adult rats | Q48231762 | ||
| Cytotoxic potential of proinflammatory cytokines: combined deletion of TNF receptors TNFR1 and TNFR2 prevents motoneuron cell death after facial axotomy in adult mouse | Q48418343 | ||
| DNA base-excision repair enzyme apurinic/apyrimidinic endonuclease/redox factor-1 is increased and competent in the brain and spinal cord of individuals with amyotrophic lateral sclerosis | Q48487103 | ||
| P433 | issue | 27 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | DNA damage | Q5205747 |
| apoptotic process | Q14599311 | ||
| P304 | page(s) | 6449-6459 | |
| P577 | publication date | 2005-07-01 | |
| P1433 | published in | Journal of Neuroscience | Q1709864 |
| P1476 | title | Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation | |
| P478 | volume | 25 |
| Q30552760 | Aberrant Regulation of DNA Methylation in Amyotrophic Lateral Sclerosis: A New Target of Disease Mechanisms |
| Q44138010 | Activation of phospholipase‐Cγ and protein kinase C signal pathways helps the survival of spinal motoneurons injured by root avulsion |
| Q38850012 | Antitumoral gene-based strategy involving nitric oxide synthase type III overexpression in hepatocellular carcinoma. |
| Q28584077 | Arginase 1 regulation of nitric oxide production is key to survival of trophic factor-deprived motor neurons |
| Q33714159 | Axotomy-induced target disconnection promotes an additional death mechanism involved in motoneuron degeneration in amyotrophic lateral sclerosis transgenic mice |
| Q36488715 | Biology of Mitochondria in Neurodegenerative Diseases |
| Q37249162 | Chromatin modifications associated with DNA double-strand breaks repair as potential targets for neurological diseases |
| Q34596260 | Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL. |
| Q38594655 | Clinical and neurobiological advances in promoting regeneration of the ventral root avulsion lesion. |
| Q35604588 | Complex regulation of p73 isoforms after alteration of amyloid precursor polypeptide (APP) function and DNA damage in neurons |
| Q41819878 | Compromised proteasome degradation elevates neuronal nitric oxide synthase levels and induces apoptotic cell death |
| Q89471917 | DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations |
| Q37760947 | DNA damage and impairment of DNA repair in Alzheimer's disease |
| Q36775988 | DNA damage and repair: relevance to mechanisms of neurodegeneration |
| Q33975101 | Differential gene expression in the axotomized facial motor nucleus of presymptomatic SOD1 mice |
| Q39133838 | Down‐regulation of apurinic/apyrimidinic endonuclease 1 (APE1) in spinal motor neurones under oxidative stress |
| Q37567755 | Electroacupuncture treatment contributes to the downregulation of neuronal nitric oxide synthase and motoneuron death in injured spinal cords following root avulsion of the brachial plexus |
| Q30485701 | Embryonic nervous system genes predominate in searches for dinucleotide simple sequence repeats flanked by conserved sequences |
| Q39990782 | Endothelial nitric oxide synthase overexpression by neuronal cells in neurodegeneration: a link between inflammation and neuroprotection |
| Q40672836 | Enforced DNA repair enzymes rescue neurons from apoptosis induced by target deprivation and axotomy in mouse models of neurodegeneration |
| Q28469285 | Enhanced astrocytic nitric oxide production and neuronal modifications in the neocortex of a NOS2 mutant mouse |
| Q35614360 | Epigenetic Regulation of Motor Neuron Cell Death through DNA Methylation |
| Q28547482 | Evaluation of Avulsion-Induced Neuropathology in Rat Spinal Cords with 18F-FDG Micro-PET/CT |
| Q80182894 | Expression of CAPON after spinal cord injury in rats |
| Q39953574 | Expressive proteomics profile changes of injured human brain cortex due to acute brain trauma |
| Q40097500 | GEA 3162, a peroxynitrite donor, induces Bcl-2-sensitive, p53-independent apoptosis in murine bone marrow cells |
| Q46891717 | Glycoursodeoxycholic acid reduces matrix metalloproteinase-9 and caspase-9 activation in a cellular model of superoxide dismutase-1 neurodegeneration |
| Q35977391 | Identification of the Avulsion-Injured Spinal Motoneurons |
| Q34441113 | Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice |
| Q39128520 | Inhibitory effect of carbazolequinone derivatives on lipopolysaccharide and interferon-γ-induced nitric oxide production in mouse macrophage RAW264.7 cells |
| Q37272764 | KNS-760704 [(6R)-4,5,6,7-tetrahydro-N6-propyl-2, 6-benzothiazole-diamine dihydrochloride monohydrate] for the treatment of amyotrophic lateral sclerosis. |
| Q41767433 | L-arginine and Alzheimer's disease. |
| Q24319929 | Lifeguard/neuronal membrane protein 35 regulates Fas ligand-mediated apoptosis in neurons via microdomain recruitment |
| Q34485199 | Lithium enhances survival and regrowth of spinal motoneurons after ventral root avulsion |
| Q36062886 | Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells |
| Q39606011 | Methyl galbanate, a novel inhibitor of nitric oxide production in mouse macrophage RAW264.7 cells |
| Q34502221 | Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases |
| Q34038775 | Mitochondrial pathobiology in ALS |
| Q30573776 | Mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice |
| Q36733211 | Motor neuron degeneration in a mouse model of seipinopathy. |
| Q53588721 | Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death |
| Q35027903 | Motor neuron trophic factors: Therapeutic use in ALS? |
| Q43117895 | NADPH-diaphorase activity in motoneurons in different segments of the spinal cord in white rats in normal conditions and after deafferentation |
| Q35563902 | NF-κB regulates caspase-4 expression and sensitizes neuroblastoma cells to Fas-induced apoptosis |
| Q37824455 | NO orchestrates the loss of synaptic boutons from adult "sick" motoneurons: modeling a molecular mechanism |
| Q91638254 | Neonatal Brain Injury and Genetic Causes of Adult-Onset Neurodegenerative Disease in Mice Interact With Effects on Acute and Late Outcomes |
| Q91905451 | Network-centric medicine for peripheral nerve injury: Treating the whole to boost endogenous mechanisms of neuroprotection and regeneration |
| Q37724332 | Neuronal cell death in neonatal hypoxia-ischemia |
| Q53573296 | Neuroprotective effects of TJ-23 (Tokishakuyakusan) on adult rat motoneurons following peripheral facial nerve axotomy |
| Q50474043 | Nitric oxide regulates cell survival in purified cultures of avian retinal neurons: involvement of multiple transduction pathways |
| Q34092226 | Nitric oxide-mediated oxidative damage and the progressive demise of motor neurons in ALS. |
| Q24596378 | Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis |
| Q37028217 | P2X7 receptor‐induced death of motor neurons by a peroxynitrite/FAS‐dependent pathway |
| Q46599168 | Peroxynitrite mediates high glucose-induced osteoblast apoptosis |
| Q46746388 | Post-hypoxic cellular disintegration in glycine-preserved renal tubules is attenuated by hydroxyl radical scavengers and iron chelators |
| Q37863791 | Potentials and limitations of peripheral nerve injury models in rodents with particular reference to the femoral nerve |
| Q53640432 | Protective effects of extract of Ginkgo biloba (EGb 761) on nerve cells after spinal cord injury in rats |
| Q42948890 | Quantum dot-induced cell death involves Fas upregulation and lipid peroxidation in human neuroblastoma cells |
| Q42105382 | Regulation of cell death receptor S-nitrosylation and apoptotic signaling by Sorafenib in hepatoblastoma cells. |
| Q38547024 | Releasing 'brakes' to nerve regeneration: intrinsic molecular targets |
| Q84860567 | Role of death receptor, mitochondrial and endoplasmic reticulum pathways in different stages of degenerative human lumbar disc |
| Q37156433 | Signaling by death receptors in the nervous system |
| Q50945630 | Simvastatin induces caspase-dependent apoptosis and activates P53 in OCM-1 cells |
| Q37122510 | Skeletal Muscle Calpain Acts through Nitric Oxide and Neural miRNAs to Regulate Acetylcholine Release in Motor Nerve Terminals |
| Q33832905 | Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice |
| Q80548042 | Spatiotemporal expression of Dexras1 after spinal cord transection in rats |
| Q80237081 | Spatiotemporal expression of PSD-95 and nNOS after rat sciatic nerve injury |
| Q38969736 | TDP-43/FUS in motor neuron disease: Complexity and challenges. |
| Q34806557 | The Mitochondrial Permeability Transition Pore Regulates Nitric Oxide-Mediated Apoptosis of Neurons Induced by Target Deprivation |
| Q37261104 | The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice |
| Q37466115 | The mitochondrial permeability transition pore: a molecular target for amyotrophic lateral sclerosis therapy |
| Q36861432 | Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration |
| Q42957375 | Transgenic neuronal nitric oxide synthase expression induces axotomy-like changes in adult motoneurons |
| Q50332669 | Tubulation repair mitigates misdirection of regenerating motor axons across a sciatic nerve gap in rats |
| Q28506214 | Unique anti-apoptotic activity of EAAC1 in injured motor neurons |
| Q33613350 | Use of laser microdissection in the investigation of facial motoneuron and neuropil molecular phenotypes after peripheral axotomy |
| Q34973926 | p53 and Cell Cycle Proteins Participate in Spinal Motor Neuron Cell Death in ALS |
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