Kinase cascades regulating entry into apoptosis

scientific article published on March 1997

Kinase cascades regulating entry into apoptosis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P932PMC publication ID232599
P698PubMed publication ID9106363

P2093author name stringAnderson P
P2860cites workE2F-1 functions in mice to promote apoptosis and suppress proliferationQ71129257
The interferon-induced double-stranded RNA-activated protein kinase induces apoptosisQ71613218
Cdc2 activation is not required for thymocyte apoptosisQ72128900
Androgen ablation-induced programmed death of prostatic glandular cells does not involve recruitment into a defective cell cycle or p53 inductionQ72164726
Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell deathQ72247935
Thymic CD45 tyrosine phosphatase regulates apoptosis and MHC-restricted negative selectionQ72332833
Protein kinase C mediates basic fibroblast growth factor protection of endothelial cells against radiation-induced apoptosisQ72386175
Programmed cell death in DictyosteliumQ72592152
Okadaic acid inhibits glucocorticoid-induced apoptosis in T cell hybridomas at its late stageQ72673517
Interleukin-3 and bryostatin-1 mediate hyperphosphorylation of BCL2 alpha in association with suppression of apoptosisQ72724791
Activation of beta-isozyme of protein kinase C (PKC beta) is necessary and sufficient for phorbol ester-induced differentiation of HL-60 promyelocytes. Studies with PKC beta-defective PET mutantQ72772868
Ordering S phase and M phase in the cell cycleQ72790820
Mitosis in transitionQ72790826
Microinjected catalytic subunit of cAMP-dependent protein kinase induces apoptosis in myeloid leukemia (IPC-81) cellsQ72967509
Calcium-dependent killing of immature thymocytes by stimulation via the CD3/T cell receptor complexQ93519952
Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosisQ24307757
Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell deathQ24310279
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell deathQ24311298
Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinaseQ24311353
Interleukin 1 is processed and released during apoptosisQ24315035
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap functionQ24324452
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell deathQ24336389
Multiple Bcl-2 family members demonstrate selective dimerizations with BaxQ24561496
The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell deathQ24563323
Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivoQ24563365
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue KineticsQ24564912
Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1Q24617367
Calcineurin functions in Ca(2+)-activated cell death in mammalian cellsQ24672398
Disruption of epithelial cell-matrix interactions induces apoptosisQ24673611
The retinoblastoma protein and cell cycle controlQ27860722
PIK-related kinases: DNA repair, recombination, and cell cycle checkpointsQ27934828
Bcl-2 associates with the ras-related protein R-ras p23Q28256068
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzymeQ28256420
Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificitiesQ28274328
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complexQ28283294
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzymeQ28287610
Programmed cell death. A rich harvest.Q52540395
Calcineurin activation protects T cells from glucocorticoid-induced apoptosis.Q54170262
Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell deathQ54485016
Programmed cell death in Caenorhabditis elegansQ57939597
Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosisQ59061176
Adenosine receptor-mediated accumulation of cyclic AMP-induced T-lymphocyte death through internucleosomal DNA cleavageQ67655958
Programmed T lymphocyte death. Cell activation- and steroid-induced pathways are mutually antagonisticQ68163837
Calcium-activated DNA fragmentation kills immature thymocytesQ69194632
The biology of cell death in tumoursQ70084663
Programmed cell death induced by ceramideQ70619078
Tumor induction and tissue atrophy in mice lacking E2F-1Q71129252
Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils.Q35882747
Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinaseQ36039597
Modulation of vinblastine cytotoxicity by dilantin (phenytoin) or the protein phosphatase inhibitor okadaic acid involves the potentiation of anti-mitotic effects and induction of apoptosis in human tumour cellsQ36134474
Internucleosomal DNA cleavage and neuronal cell survival/deathQ36232837
R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism.Q36235698
Rescue from granzyme B-induced apoptosis by Wee1 kinaseQ36364957
DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosisQ36365577
Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic deathQ36366579
Proteolysis and the biochemistry of life-or-death decisionsQ36366734
Apoptosis: Mechanisms and Roles in PathologyQ36508777
Extracellular ATP as a trigger for apoptosis or programmed cell deathQ36529115
Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activityQ36530349
The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cellsQ36557701
A study of protein kinase C isozyme distribution in relation to Bcl-2 expression during apoptosis of epithelial cells in vivoQ36741550
Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell deathQ37218100
Autoantibodies to DNA-dependent protein kinase. Probes for the catalytic subunitQ37353084
Oligopyrimidine tract at the 5' end of mammalian ribosomal protein mRNAs is required for their translational controlQ37483613
Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.Q37554227
Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alphaQ37617716
Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.Q37626367
The molecular biology of apoptosisQ37688810
Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B.Q37706911
The generation and fate of thymocytesQ37836693
Developmental cell death: morphological diversity and multiple mechanismsQ37922145
Antiapoptotic effect of heterozygously expressed mutant RI (Ala336-->Asp) subunit of cAMP kinase I in a rat leukemia cell lineQ38320142
Genetic control of programmed cell death in DrosophilaQ38468332
MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiationQ40016694
PITSLRE protein kinase activity is associated with apoptosisQ40021263
Activation-induced T-cell death is cell cycle dependent and regulated by cyclin B.Q40021594
The extracellular matrix as a cell survival factorQ40241699
Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.Q40300975
Programmed cell death by default in embryonic cells, fibroblasts, and cancer cellsQ40367172
Protein serine/threonine kinases of the MAPK cascadeQ40374614
Protein phosphorylation in apoptosis.Q40375574
The interferon system: a review with emphasis on the role of PKR in growth controlQ40400355
Ras target proteins in eukaryotic cellsQ40412995
The protein kinase C and protein kinase C related gene families.Q40428353
Src family protein tyrosine kinases and cellular signal transduction pathwaysQ40444974
Molecular control of life and deathQ40444997
Lymphocyte Death, p53, and the Problem of the “Undead” CellQ40460103
FAP-1: a protein tyrosine phosphatase that associates with FasQ28287693
The MAPK signaling cascadeQ28292599
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cellsQ28294137
Caenorhabditis elegans gene ced-9 protects cells from programmed cell deathQ28299039
Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activityQ28306175
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shockQ28307404
Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell deathQ28507741
Involvement of CD45 in adhesion and suppression of apoptosis of mouse malignant T-lymphoma cellsQ28584774
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hairQ28586758
bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestineQ28586868
Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopeniaQ28591736
Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric miceQ28593186
P53, cell cycle control and apoptosis: Implications for cancerQ28611435
Apoptosis: molecular regulation of cell deathQ28611445
Protein kinase C: structure, function, and regulationQ28618608
Induction of a Common Pathway of Apoptosis by StaurosporineQ29042381
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosisQ29547567
Inhibitors of mammalian G1 cyclin-dependent kinasesQ29547907
The mitogen-activated protein kinase signal transduction pathwayQ29620226
Mutagenesis in S49 mouse lymphoma cells: induction of resistance to ouabain, 6-thioguanine, and dibutyryl cyclic AMPQ30374640
E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factorQ33856709
Role for ceramide as an endogenous mediator of Fas-induced cytotoxicityQ33980970
The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell deathQ34214723
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.Q34320792
R-Ras induces malignant, but not morphologic, transformation of NIH3T3 cellsQ34324162
Inactivation of Bcl-2 by phosphorylationQ34340301
Phagocyte recognition of cells undergoing apoptosisQ34355692
Social controls on cell survival and cell deathQ34372181
Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathwayQ34889125
Activation of cyclin A-dependent protein kinases during apoptosisQ35195381
Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA familyQ35234179
c-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycleQ35538874
Cell death in the oligodendrocyte lineageQ35615473
The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2.Q35647500
The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism.Q35850116
Calcium and Cyclosporin A in the Regulation of ApoptosisQ40460179
Ceramide: an endogenous regulator of apoptosis and growth suppression.Q40475292
Regulation of nuclear transcription factors by stress signals.Q40480368
Apoptosis and the cell cycle.Q40481774
Ceramide: a stress signal and mediator of growth suppression and apoptosis.Q40481788
Parallel signal processing among mammalian MAPKsQ40501929
Programmed cell death and the control of cell survivalQ40585928
Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell deathQ40732702
The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signalingQ40751632
Control of oligodendrocyte number in the developing rat optic nerveQ40753787
Anchorage dependence, integrins, and apoptosisQ40754534
Programmed cell death and the control of cell survival: lessons from the nervous systemQ40777905
Extracellular signals and reversible protein phosphorylation: what to Mek of it all.Q40831207
Both ATF-2 and c-Jun are phosphorylated by stress-activated protein kinases in response to UV irradiationQ40928358
Life, death, and the pursuit of apoptosis.Q40942974
Cell cycle-related protein kinases and T cell deathQ40967554
Interactions between Ras and Raf: key regulatory proteins in cellular transformationQ40974378
ICE family proteases: mediators of all apoptotic cell death?Q40983833
The origin of programmed cell deathQ40998626
A license to killQ41016399
A signaling pathway to translational controlQ41073792
Protein kinase cascades activated by stress and inflammatory cytokinesQ41075765
Cdc25 cell-cycle phosphatase as a target of c-mycQ41175989
Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.Q41183906
A physical interaction between the cell death protein Fas and the tyrosine kinase p59fynT.Q41216168
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.Q41218044
T cell apoptosis induced by interleukin-2 deprivation or transforming growth factor-beta 2: modulation by the phosphatase inhibitors okadaic acid and calyculin A.Q41268575
Casein kinase-1 phosphorylates the p75 tumor necrosis factor receptor and negatively regulates tumor necrosis factor signaling for apoptosisQ41284110
Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.Q41284156
Induction of apoptosis in mature T cells by tumour necrosis factorQ41293478
Induction of Cyclin B and H1 Kinase Activity in Apoptotic PC12 CellsQ41317210
Immunoreceptor tyrosine-based activation motif is required to signal pathways of receptor-mediated growth arrest and apoptosis in murine B lymphoma cellsQ41325522
Intracellular internalization and signaling pathways triggered by the large subunit of HSV-2 ribonucleotide reductase (ICP10).Q41326269
Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosisQ41357125
v-Abl-mediated apoptotic suppression is associated with SHC phosphorylation without concomitant mitogen-activated protein kinase activation.Q41359429
Role for ceramide in cell cycle arrest.Q41370969
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)Q41371079
Induction of apoptosis in cultured retinoblastoma cells by the protein phosphatase inhibitor, okadaic acidQ41405764
Characterization of a renal epithelial cell model of apoptosis using okadaic acid and the NRK-52E cell lineQ41433643
Apoptosis regulation by interaction of Bcl-2 protein and Raf-1 kinase.Q41444236
Differential induction of apoptosis in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A.Q41445992
Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis.Q41447343
Mechanisms of programmed cell death and Bcl-2 protectionQ41452549
The role of protein kinase C in myeloid cell apoptosis.Q41452555
A common pathway mediates retinoic acid and PMA-dependent programmed cell death (apoptosis) of neuronal cellsQ41473065
Phorbol esters can protect mouse pre-T cell lines from radiation-induced rapid interphase apoptosisQ41485360
The phosphoprotein phosphatase calcineurin controls calcium-dependent apoptosis in B cell linesQ41489248
Activation of the Abelson tyrosine kinase activity is associated with suppression of apoptosis in hemopoietic cellsQ41559745
Calyculin A, a potent inhibitor of phosphatases-1 and -2A, prevents apoptosisQ41578574
Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinaseQ41602853
Expression of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for virus growth and neoplastic transformationQ41622961
Ceramide stimulates a cytosolic protein phosphataseQ41635180
Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.Q42830166
PHAS-I as a link between mitogen-activated protein kinase and translation initiationQ42833060
Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinaseQ42835297
Role of protein kinase-C in thymocyte apoptosis induced by irradiationQ43433730
Activation of a suicide process of thymocytes through DNA fragmentation by calcium ionophores and phorbol estersQ43453817
Epidermal growth factor and basic fibroblast growth factor suppress the spontaneous onset of apoptosis in cultured rat ovarian granulosa cells and follicles by a tyrosine kinase-dependent mechanism.Q45967902
FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathwayQ46885906
Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.Q46925453
An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitorQ47069461
Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytesQ47593158
Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.Q48377324
Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor.Q52224307
Premature p34cdc2 activation required for apoptosis.Q52514157
P433issue1
P921main subjectapoptotic processQ14599311
P304page(s)33-46
P577publication date1997-03-01
P1433published inMicrobiology and Molecular Biology ReviewsQ6839270
P1476titleKinase cascades regulating entry into apoptosis
P478volume61

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