Differential internalization and nuclear uncoating of self-complementary adeno-associated virus pseudotype vectors as determinants of cardiac cell transduction

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Differential internalization and nuclear uncoating of self-complementary adeno-associated virus pseudotype vectors as determinants of cardiac cell transduction is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1006546134
P356DOI10.1038/SJ.GT.3302987
P698PubMed publication ID17611587
P5875ResearchGate publication ID6225381

P2093author name stringWang X
Fechner H
Poller W
Weger S
Pinkert S
Sipo I
Suckau L
P2860cites workMembrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virionsQ24531466
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapyQ24535690
Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesisQ24684374
Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriersQ28144562
Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesisQ28213353
Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectorsQ30975099
Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activationQ33604753
Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2.Q33781976
Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblastsQ33796712
Adeno-associated virus type 2-mediated gene transfer: altered endocytic processing enhances transduction efficiency in murine fibroblastsQ33839187
Molecular characterization of adeno-associated viruses infecting childrenQ34142840
Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivoQ34277742
Systemic delivery of genes to striated muscles using adeno-associated viral vectors.Q34347199
AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infectionQ34486863
Identification and characterization of novel adeno-associated virus isolates in ATCC virus stocksQ34647917
Alpha2,3 and alpha2,6 N-linked sialic acids facilitate efficient binding and transduction by adeno-associated virus types 1 and 6Q35024289
Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.Q35025591
The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9Q35101411
Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypesQ35139648
Second-strand genome conversion of adeno-associated virus type 2 (AAV-2) and AAV-5 is not rate limiting following apical infection of polarized human airway epitheliaQ35150199
Intracellular trafficking of adeno-associated viral vectors.Q36097743
Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats.Q36441343
Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectorsQ36509889
Role of cellular FKBP52 protein in intracellular trafficking of recombinant adeno-associated virus 2 vectorsQ37005491
Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse heartsQ37610441
Intracellular viral processing, not single-stranded DNA accumulation, is crucial for recombinant adeno-associated virus transductionQ37682933
Adeno-associated virus-mediated gene transfer of the heart/muscle adenine nucleotide translocator (ANT) in mouseQ39371961
Infectious entry pathway of adeno-associated virus and adeno-associated virus vectorsQ39589898
Adenovirus-facilitated nuclear translocation of adeno-associated virus type 2.Q39685806
Adeno-associated virus 2-mediated gene transfer: role of a cellular serine/threonine protein phosphatase in augmenting transduction efficiencyQ40205113
Metabolic biotinylation provides a unique platform for the purification and targeting of multiple AAV vector serotypesQ40290223
Adeno-associated virus types 5 and 6 use distinct receptors for cell entryQ40330670
Impaired nuclear transport and uncoating limit recombinant adeno-associated virus 2 vector-mediated transduction of primary murine hematopoietic cells.Q40463241
Myocardial gene transfer and long-term expression following intracoronary delivery of adeno-associated virusQ40498312
Hepatocyte growth factor receptor is a coreceptor for adeno-associated virus type 2 infection.Q40726384
Infection of purified nuclei by adeno-associated virus 2.Q40775943
High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomesQ42424212
rAAV2 traffics through both the late and the recycling endosomes in a dose-dependent fashionQ43108748
Real-time single-molecule imaging of the infection pathway of an adeno-associated virusQ43812869
Efficacy and safety of adeno-associated viral vectors based on serotype 8 and 9 vs. lentiviral vectors for hemophilia B gene therapyQ44405190
Widespread and early myocardial gene expression by adeno-associated virus vector type 6 with a beta-actin hybrid promoter.Q44453756
Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduction in vivoQ45413958
Suppression of atherogenesis by delivery of TGFbeta1ACT using adeno-associated virus type 2 in LDLR knockout miceQ45417393
Chronic recurrent myocardial ischemic injury is significantly attenuated by pre-emptive adeno-associated virus heme oxygenase-1 gene deliveryQ45420121
High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated virusesQ45422901
Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heartQ45507049
Efficient transduction of skeletal muscle using vectors based on adeno-associated virus serotype 6.Q45571369
Recombinant adeno-associated virus purification using novel methods improves infectious titer and yieldQ45747699
A novel tetracycline-controlled transactivator-transrepressor system enables external control of oncolytic adenovirus replicationQ45864768
Biology of AAV serotype vectors in liver-directed gene transfer to nonhuman primates.Q45887588
Sustained whole-body functional rescue in congestive heart failure and muscular dystrophy hamsters by systemic gene transferQ45887681
Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene deliveryQ45888008
Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors.Q51278877
Persistent liver expression of murine apoA-l using vectors based on adeno-associated viral vectors serotypes 5 and 1.Q54648839
Robust Adenoviral and Adeno-Associated Viral Gene Transfer to the In Vivo Murine HeartQ58198543
Heme oxygenase-1 (HO-1) inhibits postmyocardial infarct remodeling and restores ventricular functionQ95821951
P433issue18
P921main subjectvector-borne diseaseQ2083837
P304page(s)1319-1329
P577publication date2007-07-05
P1433published inGene TherapyQ15763095
P1476titleDifferential internalization and nuclear uncoating of self-complementary adeno-associated virus pseudotype vectors as determinants of cardiac cell transduction
P478volume14

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cites work (P2860)
Q35132004A novel artificial microRNA expressing AAV vector for phospholamban silencing in cardiomyocytes improves Ca2+ uptake into the sarcoplasmic reticulum.
Q42225050AAV8 capsid variable regions at the two-fold symmetry axis contribute to high liver transduction by mediating nuclear entry and capsid uncoating.
Q38685537Adeno-Associated Virus Vectors and Stem Cells: Friends or Foes?
Q34132686Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat.
Q39973047Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathy
Q93081530Cell-specific CRISPR-Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins
Q97527308Effects of Thermally Induced Configuration Changes on rAAV Genome's Enzymatic Accessibility
Q43173416Enhancement of adeno-associated virus infection by mobilizing capsids into and out of the nucleolus
Q98292031Gene Therapy Preserves Retinal Structure and Function in a Mouse Model of NMNAT1-Associated Retinal Degeneration
Q83556143Gene therapy for heart failure
Q40516718Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional Cis-regulatory motifs that enable efficient cardiac gene therapy
Q35734826Intracellular transport of recombinant adeno-associated virus vectors
Q88540277Myoediting: Toward Prevention of Muscular Dystrophy by Therapeutic Genome Editing
Q35621815Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 achieves global cardiac gene transfer in canines.
Q34166253RH10 provides superior transgene expression in mice when compared with natural AAV serotypes for neonatal gene therapy
Q36953325Recombinant adeno-associated virus transduction and integration
Q34593758Recombinant adeno-associated virus utilizes cell-specific infectious entry mechanisms
Q59352976Reverse transduction can improve efficiency of AAV vectors in transduction-resistant cells
Q34804660Self-complementary AAV vectors; advances and applications
Q35431994Self-complementary adeno-associated viral vectors for gene therapy of hemophilia B: progress and challenges
Q28579249Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins
Q37804497The next step in gene delivery: Molecular engineering of adeno-associated virus serotypes
Q39406314Unique characteristics of AAV1, 2, and 5 viral entry, intracellular trafficking, and nuclear import define transduction efficiency in HeLa cells.
Q30398001Vaccine protection against lethal homologous and heterologous challenge using recombinant AAV vectors expressing codon-optimized genes from pandemic swine origin influenza virus (SOIV).
Q43703662microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors

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