review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1126/SCIENCE.6356363 |
P953 | full work available at URL | https://syndication.highwire.org/content/doi/10.1126/science.6356363 |
P698 | PubMed publication ID | 6356363 |
P5875 | ResearchGate publication ID | 16840654 |
P2093 | author name string | R. D. Palmiter | |
R. L. Brinster | |||
G. Norstedt | |||
R. E. Hammer | |||
R. E. Gelinas | |||
P2860 | cites work | A practical approach for quantitating specific mRNAs by solution hybridization | Q71021350 |
Effects of growth hormone, prolactin and thyroxine on body wegith, somatomedin-like activity and in-vivo sulphation of cartilage in hypopituitary dwarf mice | Q71243947 | ||
Lack of Response of Serum Somatomedin to Hyperprolactinemia in Humans* | Q72842064 | ||
Hepatic Binding of Human and Bovine Growth Hormones and Ovine Prolactin in the Dwarf “Little” Mouse* | Q24301321 | ||
The human growth hormone gene family: structure and evolution of the chromosomal locus | Q24606910 | ||
Stimulation of growth in the little mouse | Q28513361 | ||
Hypothalamic Polypeptide That Inhibits the Secretion of Immunoreactive Pituitary Growth Hormone | Q34216319 | ||
Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs | Q34253051 | ||
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes | Q34274059 | ||
Nucleotide sequence of part of the gene for human chorionic somatomammotropin: Purification of DNA complementary to predominant mRNA species | Q39453533 | ||
The insulin-like growth factors (IGF) of human serum: chemical and biological characterization and aspects of their possible physiological role. | Q40325756 | ||
Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone | Q40841038 | ||
Structure of mouse metallothionein-I gene and its mRNA. | Q42268759 | ||
Age- and Sex-Related Differences in Episodic Growth Hormone Secretion in the Rat* | Q45154586 | ||
Chromosomal position effects determine transcriptional potential of integrated mammary tumor virus DNA. | Q45799701 | ||
Regulation of metallothionein–thymidine kinase fusion plasmids injected into mouse eggs | Q48405546 | ||
Studies of GH Secretion in Mice by a Homologous Radioimmunoassay for Mouse GH1 | Q48729522 | ||
Characterization of a growth hormone-releasing factor from a human pancreatic islet tumour | Q48872563 | ||
The OFG and BrAB-OFG methods for staining the adenohypophysis. | Q51299894 | ||
Correct developmental expression of a cloned alcohol dehydrogenase gene transduced into the drosophila germ line | Q52280401 | ||
Developmental patterns of insulin-like growth factor-I and -II synthesis and regulation in rat fibroblasts | Q52282126 | ||
The cloned dopa decarboxylase gene is developmentally regulated when reintegrated into the drosophila genome | Q52517175 | ||
The effect of chromosomal position on the expression of the Drosophila xanthine dehydrogenase gene. | Q52519026 | ||
Somatomedin: Proposed Designation for Sulphation Factor | Q59080510 | ||
Insulin-like growth factor I stimulates growth in hypophysectomized rats | Q59080519 | ||
Ovine placental lactogen induces somatomedin: a a possible role in fetal growth | Q67694544 | ||
Sequence analysis of somatomedin-C: confirmation of identity with insulin-like growth factor I | Q70256223 | ||
Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring | Q70448542 | ||
P433 | issue | 4625 | |
P407 | language of work or name | English | Q1860 |
P1104 | number of pages | 6 | |
P304 | page(s) | 809-814 | |
P577 | publication date | 1983-11-01 | |
1983-11-18 | |||
P1433 | published in | Science | Q192864 |
P1476 | title | Metallothionein-human GH fusion genes stimulate growth of mice | |
Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice | |||
P478 | volume | 222 |
Q37578295 | A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene |
Q34601582 | A Drosophila gene is subject to glucose repression |
Q36386997 | A QUANTITATIVE GENETIC ANALYSIS OF BRAIN AND BODY SIZE ASSOCIATIONS, THEIR ORIGIN AND ONTOGENY: DATA FROM MICE. |
Q34666727 | A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan. |
Q43244050 | A defective HSV-1 vector expresses Escherichia coli beta-galactosidase in cultured peripheral neurons |
Q36915856 | A foreign dihydrofolate reductase gene in transgenic mice acts as a dominant mutation |
Q34019993 | A robust inducible-repressible promoter greatly facilitates gene knockouts, conditional expression, and overexpression of homologous and heterologous genes in Tetrahymena thermophila |
Q34381923 | A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice |
Q35932735 | Aberrant melanogenesis and melanocytic tumour development in transgenic mice that carry a metallothionein/ret fusion gene |
Q59080915 | Abnormal sexual development in transgenic mice chronically expressing Müllerian inhibiting substance |
Q37359089 | Accelerated growth and visceral lesions in transgenic mice expressing foreign genes of the growth hormone family: an overview |
Q46334847 | Acute leukaemia in bcr/abl transgenic mice |
Q34807993 | Adenovirus-mediated regulable target gene expression in vivo |
Q51761057 | Alterations in the mechanical properties and composition of skin in human growth hormone transgenic mice. |
Q37352313 | Altering nutrient utilization in animals through transgenesis |
Q41571009 | An Electrochemical Detection of Metallothioneins at the Zeptomole Level in Nanolitre Volumes. |
Q52252995 | An autosomal dominant mutation of facial development in a transgenic mouse. |
Q36887080 | Analysis of a transgenic mouse containing simian virus 40 and v-myc sequences |
Q89686071 | Analysis of the transgene insertion pattern in a transgenic mouse strain using long-read sequencing |
Q48420738 | Animal models in psychiatric research |
Q36796684 | Autocrine human growth hormone stimulates oncogenicity of endometrial carcinoma cells. |
Q34207694 | Biological effects of growth hormone and its antagonist |
Q44123776 | Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling |
Q77925471 | Cardiac transgenic and gene-targeted mice as models of cardiac hypertrophy and failure: a problem of (new) riches |
Q36892642 | Chromosomal position and specific demethylation in enhancer sequences of germ line-transmitted retroviral genomes during mouse development |
Q45985284 | Chronic growth hormone excess is associated with increased aldosterone: a study in patients with acromegaly and in growth hormone transgenic mice. |
Q39941121 | Chronically elevated plasma C-type natriuretic peptide level stimulates skeletal growth in transgenic mice |
Q57398384 | Cloning quantitative trait loci by insertional mutagenesis |
Q74603817 | Consequences of overexpression of growth hormone in transgenic mice on liver cytochrome P450 enzymes |
Q37380433 | Contrasting effects of the SATB1 core nuclear matrix attachment region and flanking sequences of the keratin 18 gene in transgenic mice |
Q36885489 | Coordinate amplification of metallothionein I and II genes in cadmium-resistant Chinese hamster cells: implications for mechanisms regulating metallothionein gene expression |
Q36885395 | Coordinate regulation of mouse metallothionein I and II genes by heavy metals and glucocorticoids |
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Q33733923 | Cytochrome P450 1A1 promoter as a genetic switch for the regulatable and physiological expression of a plasma protein in transgenic mice |
Q35993317 | Cytolytic T cells recognize a chimeric MHC class I antigen expressed in influenza A infected transgenic mice |
Q36531225 | Cytoplasmic sequence required for basolateral targeting of LDL receptor in livers of transgenic mice |
Q44872884 | DEVELOPMENTAL QUANTITATIVE GENETICS AND THE EVOLUTION OF ONTOGENIES. |
Q47432294 | Decreased frequency of the rat growth hormone transgene in mouse populations with or without selection for increased adult body weight |
Q36753290 | Derepression of human embryonic zeta-globin promoter by a locus-control region sequence |
Q43734161 | Developmental abnormalities in transgenic mice expressing a sialic acid-specific 9-O-acetylesterase |
Q70409679 | Developmental fate of a human insulin gene in a transgenic mouse |
Q37411662 | Direct introduction of genes into rats and expression of the genes |
Q78022540 | Does growth hormone prevent or accelerate aging? |
Q44870357 | Effect of genetic background on growth of mice hemizygous for wild-type or dwarf mutated bovine growth hormone transgenes |
Q73055528 | Effects of chronically elevated growth hormone levels on polyamine metabolism in elderly transgenic mice |
Q45034115 | Effects of every-other-day feeding on prolactin regulatory mechanism in transgenic human growth hormone mice |
Q34958588 | Elements in environmental and occupational medicine |
Q35590811 | Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner |
Q89510923 | Embryo-Based Large Fragment Knock-in in Mammals: Why, How and What's Next |
Q36218140 | Endocrine secretory granules and neuronal synaptic vesicles have three integral membrane proteins in common |
Q33291228 | Enzymatic engineering of the porcine genome with transposons and recombinases |
Q36837754 | Episomal maintenance of a bovine papilloma virus vector in transgenic mice. |
Q33931482 | Erythroid-specific expression of human beta-globin genes in transgenic mice |
Q24293326 | Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2 |
Q36911673 | Estrogen regulation of the avian transferrin gene in transgenic mice |
Q37619460 | Evaluation of growth hormone (GH) action in mice: discovery of GH receptor antagonists and clinical indications |
Q47732033 | Evaluation of the safety of daily administration of capromorelin in cats |
Q70766109 | Evidence for a major gene for rapid postweaning growth in mice |
Q35526805 | Experimental and clinical applications of molecular cell biology in nutrition and metabolism |
Q42532915 | Expression of Growth Hormone Genes in Transgenic Mice |
Q35880142 | Expression of a human O6-alkylguanine-DNA-alkyltransferase cDNA in human cells and transgenic mice |
Q24557696 | Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice |
Q41632321 | Expression of heat shock-regulated human growth hormone genes containing or lacking introns by NIH-3T3 and Wish cell lines |
Q24654233 | Expression of human GLI in mice results in failure to thrive, early death, and patchy Hirschsprung-like gastrointestinal dilatation |
Q48452757 | Expression of human HPRT in the central nervous system of transgenic mice |
Q36891984 | Expression of human beta-globin genes in transgenic mice: effects of a flanking metallothionein-human growth hormone fusion gene |
Q48488820 | Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth. |
Q40768879 | Expression of insulin-like growth factor-I in transgenic mice |
Q34131334 | Expression of mutant human cystathionine beta-synthase rescues neonatal lethality but not homocystinuria in a mouse model |
Q71273745 | Expression of rabbit C-reactive protein in transgenic mice |
Q33665584 | Expression of the human growth hormone variant gene in cultured fibroblasts and transgenic mice |
Q68928702 | Expression of the pancreatic elastase I gene in transgenic mice |
Q36949639 | Expression of tissue-specific Ren-1 and Ren-2 genes of mice: comparative analysis of 5'-proximal flanking regions |
Q33729165 | Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression |
Q37545665 | Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs |
Q34267275 | Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines |
Q73676243 | From mighty mice to mighty cows |
Q34295898 | Functional rescue of the glomerulosclerosis phenotype in Mpv17 mice by transgenesis with the human Mpv17 homologue. |
Q64448553 | Gene Transfer into Sheep |
Q38174163 | Gene targeting technologies in rats: zinc finger nucleases, transcription activator-like effector nucleases, and clustered regularly interspaced short palindromic repeats |
Q35552337 | Gene therapy of murine teratocarcinoma: separate functions for insulin-like growth factors I and II in immunogenicity and differentiation. |
Q39692912 | Gene transfer into mice |
Q39581687 | Gene transfer into the nervous system |
Q36221630 | Generation of a miniature pig disease model for human Laron syndrome |
Q70150161 | Generation of transgenic mice producing a human transthyretin variant: a possible mouse model for familial amyloidotic polyneuropathy |
Q28743531 | Genetic engineering of a mouse: Dr. Frank Ruddle and somatic cell genetics |
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Q39757195 | Germ-line transformation of mice |
Q45020496 | Growth hormone and epidermal growth factor in salivary glands of giant and dwarf transgenic mice |
Q28592176 | Growth hormone and insulin-like growth factor-I enhance beta-glucuronidase gene activation by androgen in mouse kidney |
Q37183586 | Growth hormone is permissive for neoplastic colon growth |
Q34349411 | Growth hormone receptor antagonists: discovery and potential uses |
Q72928187 | Growth quantitative trait loci (QTL) on mouse chromosome 10 in a Quackenbush-Swiss x C57BL/6J backcross |
Q74582676 | Hepatocellular kinetics and the expression of growth hormone (GH) in the livers and liver tumours of GH-transgenic mice |
Q24561537 | Heterologous introns can enhance expression of transgenes in mice |
Q72456328 | High level production of human growth hormone in the milk of transgenic mice: the upstream region of the rabbit whey acidic protein (WAP) gene targets transgene expression to the mammary gland |
Q51545833 | Human glucagon gene promoter sequences regulating tissue-specific versus nutrient-regulated gene expression. |
Q37409955 | IGF-IR in neuroprotection and brain tumors |
Q36707930 | Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals |
Q67954220 | Identification of a variant growth hormone haplotype in mice selected for high body weight |
Q81739215 | Igf-I and postnatal growth of weaver mutant mice |
Q40390135 | In vitro processing of the human growth hormone primary transcript |
Q33930080 | Inducible and tissue-specific expression of human C-reactive protein in transgenic mice |
Q37689072 | Infection of cultured central nervous system neurons with a defective herpes simplex virus 1 vector results in stable expression of Escherichia coli beta-galactosidase |
Q34686189 | Infrared laser-induced gene expression in targeted single cells of Caenorhabditis elegans |
Q36957536 | Introduction of genes into the germ line of animals |
Q52273129 | Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse |
Q36425953 | Introduction to recombinant DNA. |
Q37486009 | Introns increase transcriptional efficiency in transgenic mice |
Q48118403 | Lactotroph hyperplasia in the pituitaries of female mice expressing high levels of bovine growth hormone |
Q73137247 | Ligand-inducible and liver-specific target gene expression in transgenic mice |
Q37033405 | Loss of tumorigenicity of rat glioblastoma directed by episome-based antisense cDNA transcription of insulin-like growth factor I |
Q58573104 | Mapping Transgene Insertion Sites Reveals Complex Interactions Between Mouse Transgenes and Neighboring Endogenous Genes |
Q36787518 | Meiotic expression of human ornithine transcarbamylase in the testes of transgenic mice |
Q35816965 | Metal-inducible pathology in the liver, pancreas, and kidney of transgenic mice expressing SV40 early region genes |
Q72127311 | Methylation and expression of a metallothionein promoter ovine growth hormone fusion gene (MToGH1) in transgenic mice |
Q35856545 | Mice transgenic for a vasopressin-SV40 hybrid oncogene develop tumors of the endocrine pancreas and the anterior pituitary. A possible model for human multiple endocrine neoplasia type 1. |
Q69600704 | Microinjection and expression of a mouse metallothionein human growth hormone fusion gene in fertilized salmonid eggs |
Q34620251 | Models of growth hormone and IGF-1 deficiency: applications to studies of aging processes and life-span determination |
Q67700039 | Monoclonal antibody based sandwich enzyme‐linked immunosorbent assay for chicken growth hormone |
Q52719707 | Morphogens, nutrients, and the basis of organ scaling. |
Q42491592 | Morphological changes in the kidney of dogs chronically exposed to exogenous growth hormone |
Q33622828 | Myostatin gene knockout mediated by Cas9-D10A nickase in chicken DF1 cells without off-target effect |
Q55059666 | Neuroendocrine Regulation of Growth Hormone Secretion. |
Q35222165 | Neuropeptide gene expression in transgenic animals |
Q34286367 | Not being the wrong size |
Q48453883 | Novel developmental specificity in the nervous system of transgenic animals expressing growth hormone fusion genes |
Q36706772 | Osteoblast-specific expression of growth hormone stimulates bone growth in transgenic mice |
Q51401449 | Over-expression of Adamts1 in mice alters bone mineral density. |
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Q37146368 | Overexpression of Xenopus laevis growth hormone stimulates growth of tadpoles and frogs |
Q34175241 | Overexpression of low density lipoprotein (LDL) receptor eliminates LDL from plasma in transgenic mice |
Q35599755 | Pancreatic expression of human insulin gene in transgenic mice. |
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Q45862925 | Partial correction of murine hereditary growth disorder by germ-line incorporation of a new gene |
Q67863178 | Patterns of transgene inheritance in rainbow trout (Oncorhynchus mykiss) |
Q45737657 | Peripheral neuropathies, hepatocellular carcinomas and islet cell adenomas in transgenic mice |
Q40769486 | Plant metallothioneins |
Q24611750 | Precision editing of large animal genomes |
Q54625912 | Preventing hair loss in mice. |
Q36766444 | Primer: molecular tools used for the understanding of endocrinology. |
Q34193902 | Production of transgenic rabbits, sheep and pigs by microinjection |
Q34412775 | Progranulin A-mediated MET signaling is essential for liver morphogenesis in zebrafish. |
Q39581991 | Prolactin and growth hormone |
Q36922184 | Promoter and enhancer elements from the rat elastase I gene function independently of each other and of heterologous enhancers |
Q72399477 | Prospects for Human Gene Therapy |
Q34568316 | Purification of a distinct placental lactogen receptor, a new member of the growth hormone/prolactin receptor family |
Q33967063 | Quantitative trait loci for murine growth |
Q24798892 | Rapid degradation of dominant-negative Rab27 proteins in vivo precludes their use in transgenic mouse models. |
Q36912670 | Regulated expression of a murine class I gene in transgenic mice |
Q36797664 | Regulation of expression of a sheep metallothionein 1a-sheep growth hormone fusion gene in transgenic mice. |
Q36458732 | Regulation of insulin-like growth factor I gene expression by growth hormone |
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Q80060734 | Role of the GH/IGF-I axis in the growth retardation of weaver mice |
Q37003892 | SOCS regulation of the JAK/STAT signalling pathway |
Q33930923 | Secretion of a soluble class I molecule encoded by the Q10 gene of the C57BL/10 mouse |
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Q28297142 | Size control in animal development |
Q59090762 | Specific expression of a foreign β-globin gene in erythroid cells of transgenic mice |
Q59062399 | Specific expression of an elastase–human growth hormone fusion gene in pancreatic acinar cells of transgenic mice |
Q37274042 | Strategies for designing transgenic DNA constructs |
Q83164300 | Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system |
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