scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M609138200 |
P698 | PubMed publication ID | 17082179 |
P2093 | author name string | Jagruti H Patel | |
Steven B McMahon | |||
P2860 | cites work | Molecular characterization of mitochondrial apoptosis-inducing factor | Q22001452 |
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death | Q24291746 | ||
Targeting of Miz-1 is essential for Myc-mediated apoptosis | Q24298658 | ||
The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins | Q24328753 | ||
An alternative pathway for gene regulation by Myc | Q24532791 | ||
miR-15 and miR-16 induce apoptosis by targeting BCL2 | Q24536069 | ||
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix | Q24537504 | ||
Myc represses transcription through recruitment of DNA methyltransferase corepressor | Q24557458 | ||
c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL | Q24653312 | ||
Genomic targets of the human c-Myc protein | Q24672480 | ||
c-Myc-regulated microRNAs modulate E2F1 expression | Q27861046 | ||
WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD | Q28115105 | ||
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition | Q28115131 | ||
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis | Q28189945 | ||
Myc pathways provoking cell suicide and cancer | Q28190322 | ||
Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter | Q28204860 | ||
c-MYC: more than just a matter of life and death | Q28205057 | ||
Definition of a consensus binding site for p53 | Q28207794 | ||
Negative regulation of the mammalian UV response by Myc through association with Miz-1 | Q28212421 | ||
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways | Q28213279 | ||
Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis | Q28593886 | ||
An inhibitor of Bcl-2 family proteins induces regression of solid tumours | Q29547595 | ||
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization | Q29614701 | ||
The Bcl2 family: regulators of the cellular life-or-death switch | Q29614982 | ||
Akt and 14-3-3eta regulate Miz1 to control cell-cycle arrest after DNA damage | Q33209569 | ||
MYC oncogenes and human neoplastic disease | Q33667340 | ||
Induction of cell cycle progression and acceleration of apoptosis are two separable functions of c-Myc: transrepression correlates with acceleration of apoptosis | Q33965061 | ||
Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein | Q34047970 | ||
BH3-Only proteins-essential initiators of apoptotic cell death | Q34117362 | ||
Cooperative interaction between c-myc and bcl-2 proto-oncogenes | Q34255596 | ||
Amplification of IGH/MYC fusion in clinically aggressive IGH/BCL2-positive germinal center B-cell lymphomas. | Q34413839 | ||
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion | Q35107957 | ||
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells | Q35153635 | ||
p53 and E2F-1 cooperate to mediate apoptosis | Q35185411 | ||
Promoter-binding and repression of PDGFRB by c-Myc are separable activities | Q35618448 | ||
Myc-interacting protein 1 target gene profile: a link to microtubules, extracellular signal-regulated kinase, and cell growth | Q35733509 | ||
c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression | Q35804203 | ||
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis | Q35885582 | ||
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants | Q36142180 | ||
Promoting apoptosis as a strategy for cancer drug discovery | Q36292878 | ||
Transient excess of MYC activity can elicit genomic instability and tumorigenesis | Q36455522 | ||
The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-myc P2 minimal promoter | Q36564631 | ||
Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2 | Q36678903 | ||
Enforced expression of the c-myc oncogene inhibits cell differentiation by precluding entry into a distinct predifferentiation state in G0/G1. | Q36786710 | ||
myc and src oncogenes have complementary effects on cell proliferation and expression of specific extracellular matrix components in definitive chondroblasts | Q36886471 | ||
The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins | Q37162513 | ||
Bim is a suppressor of Myc-induced mouse B cell leukemia | Q37647369 | ||
Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila | Q38317655 | ||
Max: functional domains and interaction with c-Myc | Q38331173 | ||
c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release | Q40443976 | ||
Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway | Q40495521 | ||
Skp2 regulates Myc protein stability and activity | Q40644685 | ||
Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1. | Q40769247 | ||
Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP. | Q40772219 | ||
Control of cell growth by c-Myc in the absence of cell division | Q40919064 | ||
Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis | Q41563751 | ||
Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. | Q41714456 | ||
Domains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping | Q41722866 | ||
Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment | Q42440856 | ||
c-Myc represses the proximal promoters of GADD45a and GADD153 by a post-RNA polymerase II recruitment mechanism | Q42458575 | ||
E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination | Q42814364 | ||
Autorepression of c-myc requires both initiator and E2F-binding site elements and cooperation with the p107 gene product | Q42832476 | ||
Identification of chelerythrine as an inhibitor of BclXL function | Q44408527 | ||
Analysis of genomic targets reveals complex functions of MYC. | Q47259237 | ||
Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment. | Q51211851 | ||
Expression of c-myc changes during differentiation of mouse erythroleukaemia cells. | Q51230900 | ||
Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1. | Q52053549 | ||
Analysis of the Myc and Max interaction specificity with lambda repressor-HLH domain fusions. | Q52208388 | ||
The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice | Q57338722 | ||
Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18) | Q59085244 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 5-13 | |
P577 | publication date | 2006-11-01 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | BCL2 is a downstream effector of MIZ-1 essential for blocking c-MYC-induced apoptosis | |
P478 | volume | 282 |
Q34609728 | A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins |
Q35012114 | ARF antagonizes the ability of Miz-1 to inhibit p53-mediated transactivation |
Q40092568 | An N-Myc truncation analogous to c-Myc-S induces cell proliferation independently of transactivation but dependent on Myc homology box II. |
Q37310199 | Apoptotic signaling by c-MYC. |
Q37256816 | BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma |
Q39851009 | Cytosolic acetyl-CoA synthetase affected tumor cell survival under hypoxia: the possible function in tumor acetyl-CoA/acetate metabolism |
Q52902019 | Decreased MIZ1 Expression in Severe Experimental Acute Pancreatitis: A Rat Study. |
Q39126093 | Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma |
Q42722662 | Emerging Concepts in the Analysis of Transcriptional Targets of the MYC Oncoprotein: Are the Targets Targetable? |
Q26770001 | Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function |
Q37367194 | Genome-wide identification of post-translational modulators of transcription factor activity in human B cells. |
Q35599080 | Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC. |
Q33790662 | MYC association with cancer risk and a new model of MYC-mediated repression |
Q34083178 | MYC cofactors: molecular switches controlling diverse biological outcomes |
Q92377180 | MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer |
Q24323957 | Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1 |
Q27304900 | Miz1 is a critical repressor of cdkn1a during skin tumorigenesis |
Q35104755 | Molecular mechanisms of cigarette smoke-induced proliferation of lung cells and prevention by vitamin C. |
Q38811147 | Myc Induces miRNA-Mediated Apoptosis in Response to HDAC Inhibition in Hematologic Malignancies |
Q29616653 | Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction |
Q33713849 | Nac1 interacts with the POZ-domain transcription factor, Miz1. |
Q41633837 | Nuclear factor-kappa B1 inhibits early apoptosis of glioma cells by promoting the expression of Bcl-2 |
Q36771814 | Prognostic impact of concurrent MYC and BCL6 rearrangements and expression in de novo diffuse large B-cell lymphoma. |
Q37699714 | Regulation of CDKN2B expression by interaction of Arnt with Miz-1--a basis for functional integration between the HIF and Myc gene regulatory pathways |
Q34721114 | Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1 |
Q35761146 | Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells |
Q39785267 | The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis |
Q24620437 | The Bcl-2 apoptotic switch in cancer development and therapy |
Q27010254 | The role of MIZ-1 in MYC-dependent tumorigenesis |
Q39583166 | Transcriptional regulation of Wnt inhibitory factor-1 by Miz-1/c-Myc. |
Q90797260 | c-Myc promotes tubular cell apoptosis in ischemia-reperfusion-induced renal injury by negatively regulating c-FLIP and enhancing FasL/Fas-mediated apoptosis pathway |
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