Nicos A. Nicola

biochemist

Born 1950-01-01

Nicos A. Nicola is …
instance of (P31):
humanQ5

External links are
P268Bibliothèque nationale de France ID166886337
P5361BNB person IDNicolaNicos1950-
P9984CANTIC ID981058520770406706
P11496CiNii Research ID1140845216767276288
P4228Encyclopedia of Australian Science IDP003793b
P227GND ID172290287
P1960Google Scholar author IDjVUBkl8AAAAJ
P269IdRef ID112805477
P213ISNI0000000081747982
P409Libraries Australia ID36453186
P244Library of Congress authority IDn84205226
P6634LinkedIn personal profile IDnick-nicola-09b6a91
P3835Mendeley person IDnicos-nicola
P271NACSIS-CAT author IDDA02139679
P8189National Library of Israel J9U ID987007449428605171
P1006Nationale Thesaurus voor Auteursnamen ID140327355
P1315NLA Trove people ID626231
P1015NORAF ID90811536
P496ORCID iD0000-0003-1054-7889
P3368Prabook ID318412
P3829Publons author ID1749290
P3065RERO ID (obsolete)02-A003639379
02-A003639380
P1053ResearcherIDD-2989-2011
P2038ResearchGate profile IDNicos-Nicola
P1153Scopus author ID7102817958
P11686University of Barcelona authority ID981058520770406706
P1580University of Barcelona authority ID (former scheme)a1309371
P214VIAF ID109502084
P10832WorldCat Entities IDE39PBJvhrYmM93d9Jgxpd79FKd

P166award receivedGottschalk MedalQ5588086
Officer of the Order of AustraliaQ9684829
Fellow of the Australian Academy of ScienceQ59260322
P69educated atUniversity of MelbourneQ319078
P108employerWEHIQ7966487
P101field of workimmunologyQ101929
cytokineQ212354
P106occupationbiochemistQ2919046
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q37018307A (selective) history of Australian involvement in cytokine biology
Q30858190A fusion protein system for the recombinant production of short disulfide-containing peptides.
Q33372611A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia
Q41646869Affinity conversion of receptors for colony stimulating factors: properties of solubilized receptors
Q30823978Affinity maturation of leukemia inhibitory factor and conversion to potent antagonists of signaling.
Q28586837Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development
Q27646869An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor
Q24322983Ankyrin repeat and suppressors of cytokine signaling box protein asb-9 targets creatine kinase B for degradation
Q45234484Anomalous megakaryocytopoiesis in mice with mutations in the c-Myb gene
Q48228139Behavioural and anatomical effects of systemically administered leukemia inhibitory factor in the SOD1(G93A G1H) mouse model of familial amyotrophic lateral sclerosis
Q44482541Binding, internalization, and degradation of 125I-multipotential colony-stimulating factor (interleukin-3) by FDCP-1 cells
Q44123776Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling
Q35953472Blocking Endogenous Leukemia Inhibitory Factor During Placental Development in Mice Leads to Abnormal Placentation and Pregnancy Loss
Q36288587Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: a nonhormonal contraceptive strategy.
Q62819555Cellular Processing of Murine Colony-Stimulating Factor (Multi-CSF, GM-CSF, G-CSF) Receptors by Normal Hemopoietic Cells and Cell Lines
Q62819533Clearance and fate of leukemia-inhibitory factor (LIF) after injection into mice
Q33633115Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
Q42565622Correction for Zhang et al., The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation
Q27679898Crystal structure of the TRIM25 B30.2 (PRYSPRY) domain: a key component of antiviral signalling
Q33967437Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes
Q36343007DEC-205 is a cell surface receptor for CpG oligonucleotides
Q34151625Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice
Q36219805Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT phosphorylation
Q37593683Development of hydrocephalus in mice lacking SOCS7.
Q52298375Differential expression of lectin receptors during hemopoietic differentiation: enrichment for granulocyte-macrophage progenitor cells.
Q41640389Differentiation commitment in normal hemopoiesis and leukemic transformation
Q28245196Distinct roles for leukemia inhibitory factor receptor alpha-chain and gp130 in cell type-specific signal transduction
Q62818206Donald Metcalf (1929–2014)
Q36458177Dynamics of the SPRY domain-containing SOCS box protein 2: flexibility of key functional loops
Q36346668Enhancement of human blood eosinophil cytotoxicity by semi-purified eosinophil colony-stimulating factor(s)
Q91095526Enzymatic Characterization of Wild-Type and Mutant Janus Kinase 1
Q62819858Expression of BCR – ABL in M1 myeloid leukemia cells induces differentiation without arresting proliferation
Q24550851Functional analysis of Asb-1 using genetic modification in mice
Q33412741Functional characterization of c-Mpl ectodomain mutations that underlie congenital amegakaryocytic thrombocytopenia
Q62819918Growth Factor-Induced Phosphorylation of c-rasp21 in Normal Hemopoietic Progenitor Cells
Q28201918Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)
Q42449457Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling
Q62819873Hemopoietic growth factor receptor abnormalities in leukemia
Q34933837Histidine-367 of the human common beta chain of the receptor is critical for high-affinity binding of human granulocyte-macrophage colony-stimulating factor.
Q35137626IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3.
Q58039498Identification and Characterization of Two Distinct Truncated Forms of gp130 and a Soluble Form of Leukemia Inhibitory Factor Receptor α-Chain in Normal Human Urine and Plasma
Q33453217Immuno-haematology and blood bank inventory and issue management
Q37676036Inhibition of IL-6 family cytokines by SOCS3.
Q36837473Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.
Q61989076Letter to the Editor: Backbone 1H, 13C and 15N assignments of the 25 kDa SPRY domain-containing SOCS box protein 2 (SSB-2)
Q62819864Leukemia Inhibitory Factor Is an Autocrine Survival Factor for Schwann Cells
Q38317255Ligand-specific utilization of the extracellular membrane-proximal region of the gp130-related signalling receptors.
Q36735213Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.
Q35001025Localization of the human GM-CSF receptor gene to the X-Y pseudoautosomal region.
Q44257096Macrophage cell lines transformed by the malignant histiocytosis sarcoma virus: increase of CSF receptors suggests a model for transformation
Q62818261Mechanism of crosstalk inhibition of IL-6 signaling in response to LPS and TNFα
Q33857008Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses
Q48389907Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte-macrophage colony stimulating factor
Q54645847NMR studies of a murine-human chimera of leukaemia inhibitory factor (LIF). Comparison with human LIF.
Q41816627Negative regulation of gp130 signalling mediated through tyrosine-757 is not dependent on the recruitment of SHP2.
Q24642117Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice
Q28593767Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice
Q33894724Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1).
Q47958279Polyethylene glycated leukemia inhibitory factor antagonist inhibits human blastocyst implantation and triggers apoptosis by down-regulating embryonic AKT.
Q27683911Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1
Q37696894Purification of a ligand for the EPH-like receptor HEK using a biosensor-based affinity detection approach
Q33857419Reconstruction of an active SOCS3-based E3 ubiquitin ligase complex in vitro: identification of the active components and JAK2 and gp130 as substrates
Q37172111Regulation of Janus kinases by SOCS proteins
Q36141189Regulation of multiple cytokine signalling pathways by SOCS3 is independent of SOCS2.
Q31096727SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities
Q24537559SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation
Q52174469SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.
Q27676669SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition
Q51027830SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis.
Q38354512SOCS3 negatively regulates IL-6 signaling in vivo
Q36731660SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function
Q62819899Specific binding of leukemia inhibitory factor to murine myoblasts in culture
Q40374586Structural aspects of cytokine/receptor interactions
Q38058751Structure and function of the SPRY/B30.2 domain proteins involved in innate immunity
Q52176576Suckling defect in mice lacking the soluble haemopoietin receptor NR6.
Q35822851Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity
Q31130829Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1.
Q62819428Suppressor of Cytokine Signaling-1 Attenuates the Duration of Interferon γ Signal Transductionin Vitroandin Vivo
Q62819390Suppressor of Cytokine Signaling-1 Regulates Signaling in Response to Interleukin-2 and Other γc-dependent Cytokines in Peripheral T Cells
Q28585800Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling
Q53543101Suppressor of cytokine signaling 3 regulates CD8 T-cell proliferation by inhibition of interleukins 6 and 27.
Q35165316Suppressor of cytokine signaling 4 (SOCS4) protects against severe cytokine storm and enhances viral clearance during influenza infection
Q35777741Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130
Q33695715Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling
Q58039546The Disulfide Bond Arrangement of Leukemia Inhibitory Factor: Homology to Oncostatin M and Structural Implications
Q27651007The SOCS Box Domain of SOCS3: Structure and Interaction with the ElonginBC-Cullin5 Ubiquitin Ligase
Q37289267The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression
Q35989418The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo
Q28205975The SOCS box: a tale of destruction and degradation
Q40337569The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues
Q62819890The Unusual Species Cross-reactivity of the Leukemia Inhibitory Factor Receptor α-Chain Is Determined Primarily by the Immunoglobulin-like Domain
Q62819883The biological consequences of excess GM-CSF levels in transgenic mice also lacking high-affinity receptors for GM-CSF
Q27003933The biology and mechanism of action of suppressor of cytokine signaling 3
Q40988652The box-1 region of the leukemia inhibitory factor receptor alpha-chain cytoplasmic domain is sufficient for hemopoietic cell proliferation and differentiation.
Q46941042The comparative roles of suppressor of cytokine signaling-1 and -3 in the inhibition and desensitization of cytokine signaling
Q27678371The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments
Q38334177The immunoglobulin-like module of gp130 is required for signaling by interleukin-6, but not by leukemia inhibitory factor
Q27685465The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
Q39090468The role of leukemia inhibitory factor in tubal ectopic pregnancy.
Q40289129The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.
Q34057877The suppressors of cytokine signaling (SOCS) proteins: important feedback inhibitors of cytokine action.
Q24671596Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene
Q37977396Towards a four-dimensional view of neutrophils
Q24317684Twenty proteins containing a C-terminal SOCS box form five structural classes
Q36313330Two forms of murine epidermal growth factor: rapid separation by using reverse-phase HPLC
Q33911059Vaginally administered PEGylated LIF antagonist blocked embryo implantation and eliminated non-target effects on bone in mice

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