A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction

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A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKW1274
P932PMC publication ID5389615
P698PubMed publication ID27986854

P50authorSøren HallstrømQ63386248
Qunxin SheQ30439305
Malcolm F. WhiteQ38319114
P2093author name stringJing Zhang
Nan Peng
Wenyuan Han
Ling Deng
Wenfang Peng
Yingjun Li
Mingxia Feng
Yun Xiang Liang
P2860cites workA guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomesQ21090166
Genome Analyses of Icelandic Strains of Sulfolobus islandicus, Model Organisms for Genetic and Virus-Host Interaction StudiesQ22065480
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial ImmunityQ24669850
Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunityQ26853377
Structure of the Cmr2-Cmr3 Subcomplex of the Cmr RNA Silencing ComplexQ27676268
Structure and Mechanism of the CMR Complex for CRISPR-Mediated Antiviral ImmunityQ27676627
Structure of the Cmr2 Subunit of the CRISPR-Cas RNA Silencing ComplexQ27677966
Crystal structure of Cmr2 suggests a nucleotide cyclase-related enzyme in type III CRISPR-Cas systemsQ27678215
Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune SystemQ27678641
Crystal structure of the Cmr2-Cmr3 subcomplex in the CRISPR-Cas RNA silencing effector complexQ27684409
Structural model of a CRISPR RNA-silencing complex reveals the RNA-target cleavage activity in Cmr4Q27695676
Crystal structure of the CRISPR-Cas RNA silencing Cmr complex bound to a target analogQ27700277
Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coliQ27703998
RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilusQ28649354
Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteriaQ29614420
RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complexQ29615785
CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNAQ29615786
Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elementsQ29615788
Identification of genes that are associated with DNA repeats in prokaryotesQ29615790
Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal originQ29617073
Structure and activity of the RNA-targeting Type III-B CRISPR-Cas complex of Thermus thermophilusQ33131259
Self versus non-self discrimination during CRISPR RNA-directed immunity.Q33620668
An updated evolutionary classification of CRISPR-Cas systemsQ33660852
A putative viral defence mechanism in archaeal cellsQ33998177
CRISPR-Cas immunity in prokaryotesQ34045076
Dynamic properties of the Sulfolobus CRISPR/Cas and CRISPR/Cmr systems when challenged with vector-borne viral and plasmid genes and protospacersQ34155448
Essential features and rational design of CRISPR RNAs that function with the Cas RAMP module complex to cleave RNAs.Q34245546
A novel interference mechanism by a type IIIB CRISPR-Cmr module in Sulfolobus.Q34322670
Target RNA capture and cleavage by the Cmr type III-B CRISPR-Cas effector complexQ34430749
Programmable RNA shredding by the type III-A CRISPR-Cas system of Streptococcus thermophilus.Q34451280
Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systemsQ34536517
Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complexQ34724892
Short motif sequences determine the targets of the prokaryotic CRISPR defence systemQ34953078
Cmr4 is the slicer in the RNA-targeting Cmr CRISPR complexQ35098034
Archaeal extrachromosomal genetic elementsQ35482661
Structural biology. Structures of the CRISPR-Cmr complex reveal mode of RNA target positioningQ36092029
A synthetic arabinose-inducible promoter confers high levels of recombinant protein expression in hyperthermophilic archaeon Sulfolobus islandicus.Q36120266
Bipartite recognition of target RNAs activates DNA cleavage by the Type III-B CRISPR-Cas systemQ36603869
RNA-activated DNA cleavage by the Type III-B CRISPR-Cas effector complexQ36603874
Massive activation of archaeal defense genes during viral infectionQ37036789
Multiple consecutive initiation of replication producing novel brush-like intermediates at the termini of linear viral dsDNA genomes with hairpin endsQ37336962
Genetic analyses in the hyperthermophilic archaeon Sulfolobus islandicusQ37368254
Molecular biology of fuselloviruses and their satellites.Q38190447
Adapting to new threats: the generation of memory by CRISPR-Cas immune systemsQ38210066
DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexesQ38454128
CRISPR adaptive immune systems of ArchaeaQ38597506
Harnessing Type I and Type III CRISPR-Cas systems for genome editingQ38667415
Multiple nucleic acid cleavage modes in divergent type III CRISPR systemsQ38667891
Adaptation in CRISPR-Cas SystemsQ38763260
CRISPR-mediated targeted mRNA degradation in the archaeon Sulfolobus solfataricusQ39094038
Transcriptome changes in STSV2-infected Sulfolobus islandicus REY15A undergoing continuous CRISPR spacer acquisition.Q40378937
Efficient CRISPR-Mediated Post-Transcriptional Gene Silencing in a Hyperthermophilic Archaeon Using Multiplexed crRNA Expression.Q40628722
Spatiotemporal Control of Type III-A CRISPR-Cas Immunity: Coupling DNA Degradation with the Target RNA Recognition.Q40703180
Co-transcriptional DNA and RNA Cleavage during Type III CRISPR-Cas ImmunityQ40955079
Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targetingQ41760159
Genetic determinants of PAM-dependent DNA targeting and pre-crRNA processing in Sulfolobus islandicus.Q41968713
Structure of the CRISPR interference complex CSM reveals key similarities with cascadeQ41980729
Novel insights into gene regulation of the rudivirus SIRV2 infecting Sulfolobus cellsQ42027998
In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus.Q42262732
An archaeal CRISPR type III-B system exhibiting distinctive RNA targeting features and mediating dual RNA and DNA interference.Q43097718
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue4
P921main subjectCRISPRQ412563
P304page(s)1983-1993
P577publication date2016-12-15
P1433published inNucleic Acids ResearchQ135122
P1476titleA type III-B CRISPR-Cas effector complex mediating massive target DNA destruction
P478volume45

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cites work (P2860)
Q58708478A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding
Q41924586Allosteric regulation of Csx1, a type IIIB-associated CARF domain ribonuclease by RNAs carrying a tetraadenylate tail
Q40076357Broad Targeting Specificity during Bacterial Type III CRISPR-Cas Immunity Constrains Viral Escape
Q58568511CRISPR-Based Technologies: Impact of RNA-Targeting Systems
Q98575566Chemistry of Class 1 CRISPR-Cas effectors: binding, editing, and regulation
Q47104208Cmr1 enables efficient RNA and DNA interference of a III-B CRISPR-Cas system by binding to target RNA and crRNA.
Q57753836Comprehensive search for accessory proteins encoded with archaeal and bacterial type III CRISPR-cas gene cassettes reveals 39 new cas gene families
Q39395687Conformational regulation of CRISPR-associated nucleases
Q56885795Control of cyclic oligoadenylate synthesis in a type III CRISPR system
Q92492882Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence
Q64056392Diversified local CRISPR-Cas immunity to viruses of Sulfolobus islandicus
Q90556101Regulation of the RNA and DNA nuclease activities required for Pyrococcus furiosus Type III-B CRISPR-Cas immunity
Q91665478Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble
Q41676275The CRISPR Spacer Space Is Dominated by Sequences from Species-Specific Mobilomes
Q59357210The ribonuclease activity of Csm6 is required for anti-plasmid immunity by Type III-A CRISPR-Cas systems
Q52431398Tolerance of Sulfolobus SMV1 virus to the immunity of I-A and III-B CRISPR-Cas systems in Sulfolobus islandicus.

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