Mechanisms of antigenic variation in Borrelia hermsii and African trypanosomes

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Mechanisms of antigenic variation in Borrelia hermsii and African trypanosomes is …
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review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1074/JBC.270.14.7783
P698PubMed publication ID7713867

P2093author name stringDonelson JE
P2860cites workMutation drift and repertoire shift in the maturation of the immune responseQ39658890
Programmed gene rearrangements altering gene expressionQ39756151
RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes.Q40464798
Antigen diversity in the bacterium B. hermsii through "somatic" mutations in rearranged vmp genesQ40696088
Activation of a vmp pseudogene in Borrella hermsii: an alternate mechanism of antigenic variation during relapsing feverQ40698508
Linear DNA of Borrelia species and antigenic variationQ40713853
Variable antigen genes of the relapsing fever agent Borrelia hermsii are activated by promoter additionQ40751880
Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsiiQ40813837
Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genesQ40858318
Increased UV resistance of a xeroderma pigmentosum revertant cell line is correlated with selective repair of the transcribed strand of an expressed geneQ41576125
Structure of a telomeric expression site for variant specific surface antigens in Trypanosoma bruceiQ41874288
Distribution of mutations around rearranged heavy-chain antibody variable-region genesQ41966971
A strand bias occurs in point mutations associated with variant surface glycoprotein gene conversion in Trypanosoma rhodesienseQ43181774
The anatomy and transcription of a telomeric expression site for variant-specific surface antigens in T. bruceiQ43544439
High frequency of antigenic variation in Trypanosoma brucei rhodesiense infectionsQ43798071
Stable expression of two variable surface glycoproteins by cloned Trypanosoma equiperdumQ44355348
Surface epitope variation via mosaic gene formation is potential key to long-term survival of Trypanosoma bruceiQ45178379
On the DNA content and ploidy of trypanosomesQ46198320
Telomeric reciprocal recombination as a possible mechanism for antigenic variation in trypanosomesQ46382878
Point mutations are associated with a gene duplication leading to the bloodstream reexpression of a trypanosome metacyclic VSG.Q48133443
Coordinate transcription of variant surface glycoprotein genes and an expression site associated gene family in Trypanosoma bruceiQ48376802
Two modes of activation of a single surface antigen gene of Trypanosoma bruceiQ48393331
Expression of two variant surface glycoproteins on individual African trypanosomes during antigen switching.Q53898827
Molecular mechanism of transcription-repair coupling.Q54659174
Novel expression-linked copies of the genes for variant surface antigens in trypanosomesQ59078039
Genetics: Gene conversion in the absence of reciprocal recombinationQ59084411
A structural motif in the variant surface glycoproteins of Trypanosoma bruceiQ27732130
Gene conversion as a mechanism for antigenic variation in trypanosomesQ28270944
Chromosome structure: DNA nucleotide sequence elements of a subset of the minichromosomes of the protozoan Trypanosoma bruceiQ30450327
Juxtaposition of expressed variable antigen genes with a conserved telomere in the bacterium Borrelia hermsiiQ33736067
beta-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. bruceiQ34061024
Megabase-sized linear DNA in the bacterium Borrelia burgdorferi, the Lyme disease agentQ34294965
Ordered appearance of antigenic variants of African trypanosomes explained in a mathematical model based on a stochastic switch process and immune-selection against putative switch intermediatesQ34324411
Improved separation of chromosome-sized DNA from Trypanosoma brucei, stock 427-60.Q35224456
An analysis of cosmid clones of nuclear DNA from Trypanosoma brucei shows that the genes for variant surface glycoproteins are clustered in the genome.Q35531608
Expression of a glycosylphosphatidylinositol-anchored Trypanosoma brucei transferrin-binding protein complex in insect cells.Q35574760
The genes and transcripts of an antigen gene expression site from T. bruceiQ36024960
Linear- and circular-plasmid copy numbers in Borrelia burgdorferiQ36116952
Phylogenetic analysis of the spirochetesQ36154925
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spotsQ36172034
Antigenic variation of Borrelia hermsiiQ36347079
Variable major proteins of Borrellia hermsiiQ36347108
A gene from the variant surface glycoprotein expression site encodes one of several transmembrane adenylate cyclases located on the flagellum of Trypanosoma bruceiQ36963334
Methylated DNA in Borrelia speciesQ37608757
Trypanosoma equiperdum: antigenic variations in experimental trypanosomiasis of rabbitsQ39436457
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectBorrelia hermsiiQ4946575
P1104number of pages4
P304page(s)7783-7786
P577publication date1995-04-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleMechanisms of antigenic variation in Borrelia hermsii and African trypanosomes
P478volume270

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cites work (P2860)
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