Epstein-Barr virus latent membrane protein LMP-2A is sufficient for transactivation of the human endogenous retrovirus HERV-K18 superantigen

scientific article published on July 2004

Epstein-Barr virus latent membrane protein LMP-2A is sufficient for transactivation of the human endogenous retrovirus HERV-K18 superantigen is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.78.14.7852-7860.2004
P932PMC publication ID434102
P698PubMed publication ID15220463

P2093author name stringGang Chen
Brigitte T Huber
Natalie Sutkowski
German Calderon
P2860cites workEpstein-Barr virus LMP2A-induced B-cell survival in two unique classes of EmuLMP2A transgenic miceQ24524255
Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling moduleQ24675538
Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigenQ27731278
Virus-encoded superantigensQ28776748
The CrkL adapter protein is required for type I interferon-dependent gene transcription and activation of the small G-protein Rap1.Q30167565
Epstein-Barr virus latent membrane protein transactivates the human immunodeficiency virus type 1 long terminal repeat through induction of NF-kappa B activityQ30452167
The LMP2A ITAM is essential for providing B cells with development and survival signals in vivoQ33604616
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Transgenic expression of the coxsackie/adenovirus receptor enables adenoviral-mediated gene delivery in naive T cellsQ35575723
Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1.Q35829475
Reducing the complexity of the transforming Epstein-Barr virus genome to 64 kilobase pairs.Q35832104
Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activationQ35891360
Epstein-Barr virus leader protein enhances EBNA-2-mediated transactivation of latent membrane protein 1 expression: a role for the W1W2 repeat domainQ35891377
Endogenous superantigen expression is controlled by mouse mammary tumor proviral lociQ36230541
Localization of Epstein-Barr virus cytotoxic T cell epitopes using recombinant vaccinia: implications for vaccine developmentQ36231451
An Epstein-Barr virus-associated superantigenQ36367270
Epstein-Barr virus recombinants from overlapping cosmid fragmentsQ36655212
Influence of Burkitt's lymphoma and primary B cells on latent gene expression by the nonimmortalizing P3J-HR-1 strain of Epstein-Barr virusQ36791391
Stable transfection of Epstein-Barr virus (EBV) nuclear antigen 2 in lymphoma cells containing the EBV P3HR1 genome induces expression of B-cell activation molecules CD21 and CD23.Q36801839
Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23Q36806063
Polyadenylation at correct sites in genome RNA is not required for retrovirus replication or genome encapsidationQ36829761
Superantigens: mechanism of T-cell stimulation and role in immune responsesQ37105213
A method for production of antibodies to human T-cell receptor beta-chain variable regionsQ37596850
Human cytotoxic T-cell responses against Epstein-Barr virus nuclear antigens demonstrated by using recombinant vaccinia virusesQ37737223
The Spi-1/PU.1 and Spi-B ets family transcription factors and the recombination signal binding protein RBP-J kappa interact with an Epstein-Barr virus nuclear antigen 2 responsive cis-element.Q38301679
A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-Barr virus.Q39736828
All three domains of the Epstein-Barr virus-encoded latent membrane protein LMP-1 are required for transformation of rat-1 fibroblasts.Q40044497
Different patterns of Epstein-Barr virus gene expression and of cytotoxic T-cell recognition in B-cell lines infected with transforming (B95.8) or nontransforming (P3HR1) virus strainsQ40129920
Deletion of the nontransforming Epstein-Barr virus strain P3HR-1 causes fusion of the large internal repeat to the DSL regionQ40142296
Epstein-Barr virus protein LMP2A regulates reactivation from latency by negatively regulating tyrosine kinases involved in sIg-mediated signal transductionQ40563936
Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigenQ40773245
Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hairless.Q40793575
Interferon alpha activates the tyrosine kinase Lyn in haemopoietic cells.Q41032505
Epstein-Barr virus nuclear antigen 2 is a transcriptional suppressor of the immunoglobulin mu gene: implications for the expression of the translocated c-myc gene in Burkitt's lymphoma cells.Q41063703
Regulation of Epstein-Barr virus latency by latent membrane protein 2.Q41125684
Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virusQ41976287
Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytesQ43679392
Role of Stat5 in type I interferon-signaling and transcriptional regulationQ44538997
Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signalsQ44664210
Mechanism of transduction by retrovirusesQ44823635
A maternally inherited superantigen encoded by a mammary tumour virusQ44936887
Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to LMP2A antigen: a potential treatment strategy for Epstein-Barr virus--positive Hodgkin's lymphomaQ45736315
Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappaQ45781476
New Epstein–Barr virus variants from cellular subclones of P3J-HR-1 Burkitt lymphomaQ45800799
Epstein-Barr virus latent gene expression during the initiation of B cell immortalizationQ45845786
Genes encoding ligands for deletion of Vβ11 T cells cosegregate with mammary tumour virus genomesQ45855720
The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa BQ45876441
Isolation and localization of an IDDMK1,2-22-related human endogenous retroviral gene, and identification of a CA repeat marker at its locusQ47926917
An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.Q53541156
Multiple binding sites for bacterial superantigens on soluble class II MHC moleculesQ56922183
Residues of the variable region of the T-cell-receptor β-chain that interact with S. aureus toxin superantigensQ56922307
Linkage of Mls genes to endogenous mammary tumour viruses of inbred miceQ59058079
The survival of antigen-stimulated T cells requires NFkappaB-mediated inhibition of p73 expressionQ64377884
Recombinant adenovirus coexpressing covalent peptide/MHC class II complex and B7-1: in vitro and in vivo activation of myelin basic protein-specific T cellsQ64379656
Interferon-alpha inhibits Stat5 DNA-binding in IL-2 stimulated primary T-lymphocytesQ77470217
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectEpstein–Barr virusQ6900
membrane proteinQ423042
superantigenQ772950
P1104number of pages9
P304page(s)7852-7860
P577publication date2004-07-01
P1433published inJournal of VirologyQ1251128
P1476titleEpstein-Barr virus latent membrane protein LMP-2A is sufficient for transactivation of the human endogenous retrovirus HERV-K18 superantigen
P478volume78

Reverse relations

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