scholarly article | Q13442814 |
P356 | DOI | 10.1016/J.BBRC.2003.09.104 |
P953 | full work available at URL | https://api.elsevier.com/content/article/PII:S0006291X03019089?httpAccept=text/plain |
https://api.elsevier.com/content/article/PII:S0006291X03019089?httpAccept=text/xml | ||
P698 | PubMed publication ID | 14550298 |
P50 | author | Ann Saada | Q41879584 |
P2093 | author name string | Orly Elpeleg | |
Efrat Ben-Shalom | |||
Hanna Mandel | |||
Chaya Miller | |||
Rivka Zyslin | |||
P2860 | cites work | Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder | Q22008732 |
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Inherited mitochondrial DNA depletion | Q34195471 | ||
Site-specific somatic mitochondrial DNA point mutations in patients with thymidine phosphorylase deficiency | Q35095598 | ||
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Cell cycle-dependent metabolism of pyrimidine deoxynucleoside triphosphates in CEM cells | Q41103860 | ||
mtDNA depletion myopathy: elucidation of the tissue specificity in the mitochondrial thymidine kinase (TK2) deficiency | Q42441777 | ||
Depletion of the other genome-mitochondrial DNA depletion syndromes in humans | Q44058609 | ||
Mitochondrial DNA depletion: mutations in thymidine kinase gene with myopathy and SMA. | Q44187783 | ||
Kinetic properties of mutant human thymidine kinase 2 suggest a mechanism for mitochondrial DNA depletion myopathy | Q44257239 | ||
Mutation analysis in 16 patients with mtDNA depletion. | Q44375076 | ||
Reversion of mtDNA depletion in a patient with TK2 deficiency | Q44394599 | ||
Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers | Q69359556 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | biophysics | Q7100 |
cell biology | Q7141 | ||
biochemistry | Q7094 | ||
P304 | page(s) | 963-966 | |
P577 | publication date | 2003-10-01 | |
2003-10-24 | |||
P1433 | published in | Biochemical and Biophysical Research Communications | Q864228 |
P1476 | title | Mitochondrial deoxyribonucleoside triphosphate pools in thymidine kinase 2 deficiency | |
P478 | volume | 310 |
Q34652444 | 3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity |
Q34695913 | 3'-Azido-3'-deoxythymidine (AZT) is a competitive inhibitor of thymidine phosphorylation in isolated rat heart and liver mitochondria |
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Q35535022 | A review comparing deoxyribonucleoside triphosphate (dNTP) concentrations in the mitochondrial and cytoplasmic compartments of normal and transformed cells |
Q92223851 | Age-related metabolic changes limit efficacy of deoxynucleoside-based therapy in thymidine kinase 2-deficient mice |
Q39876288 | Altered gene transcription profiles in fibroblasts harboring either TK2 or DGUOK mutations indicate compensatory mechanisms. |
Q92429246 | Bioavailability and cytosolic kinases modulate response to deoxynucleoside therapy in TK2 deficiency |
Q34131169 | Deoxypyrimidine monophosphate bypass therapy for thymidine kinase 2 deficiency. |
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Q36765849 | Mitochondrial diseases: a nosological update. |
Q34399422 | Onset and organ specificity of Tk2 deficiency depends on Tk1 down-regulation and transcriptional compensation |
Q45951063 | Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity. |
Q34652429 | Phosphorylation of thymidine and AZT in heart mitochondria: elucidation of a novel mechanism of AZT cardiotoxicity |
Q37155666 | Structure, physiological role, and specific inhibitors of human thymidine kinase 2 (TK2): present and future. |
Q39580147 | Targeted impairment of thymidine kinase 2 expression in cells induces mitochondrial DNA depletion and reveals molecular mechanisms of compensation of mitochondrial respiratory activity. |
Q41014443 | The Deoxynucleoside Triphosphate Triphosphohydrolase Activity of SAMHD1 Protein Contributes to the Mitochondrial DNA Depletion Associated with Genetic Deficiency of Deoxyguanosine Kinase |
Q37054681 | Thymidine kinase and mtDNA depletion in human cardiomyopathy: epigenetic and translational evidence for energy starvation |
Q46542423 | Transgenic expression of the deoxynucleotide carrier causes mitochondrial damage that is enhanced by NRTIs for AIDS. |
Q46156686 | Unchanged thymidine triphosphate pools and thymidine metabolism in two lines of thymidine kinase 2-mutated fibroblasts |