Host-Pathogen Coevolution and the Emergence of Broadly Neutralizing Antibodies in Chronic Infections

scientific article published on 21 July 2016

Host-Pathogen Coevolution and the Emergence of Broadly Neutralizing Antibodies in Chronic Infections is …
instance of (P31):
scholarly articleQ13442814

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P818arXiv ID1512.06296
P356DOI10.1371/JOURNAL.PGEN.1006171
P932PMC publication ID4956326
P698PubMed publication ID27442127

P50authorJakub OtwinowskiQ54901142
Joshua B. PlotkinQ57242660
Armita NourmohammadQ112339634
P2860cites workThe HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and ImmunogensQ22242262
Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infectionQ24538985
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Co-evolution of a broadly neutralizing HIV-1 antibody and founder virusQ27644501
Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120Q27658449
Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01Q27663293
Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope TrimerQ27680497
Recombination rate and selection strength in HIV intra-patient evolutionQ28472689
Inferring processes underlying B-cell repertoire diversityQ28640380
Properties and rates of germline mutations in humansQ28678675
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine targetQ29547347
Broad neutralization coverage of HIV by multiple highly potent antibodiesQ29615361
Rates of evolutionary change in viruses: patterns and determinantsQ29616174
Rapid evolution of the neutralizing antibody response to HIV type 1 infectionQ29618603
HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sitesQ29619017
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infectionQ29619738
Explaining high alloreactivity as a quantitative consequence of affinity-driven thymocyte selectionQ33333657
Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infectionQ33504604
Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoireQ33513799
Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variablesQ33614495
Fitness flux and ubiquity of adaptive evolutionQ33732926
Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infectionQ33825654
HIV evolutionary dynamics within and among hostsQ34000621
Contrasted coevolutionary dynamics between a bacterial pathogen and its bacteriophagesQ34002414
Selection and CovarianceQ34233418
Germinal centersQ34245271
A theory of germinal center B cell selection, division, and exit.Q53154491
Number and distribution of lymphocytes in man. A critical analysis.Q54298510
Host-parasite coevolutionary arms races give way to fluctuating selectionQ83973253
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Antibody landscapes after influenza virus infection or vaccination.Q34580640
The immune response during acute HIV-1 infection: clues for vaccine developmentQ34614862
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Bacteria-phage coevolution as a driver of ecological and evolutionary processes in microbial communitiesQ34637653
From fitness landscapes to seascapes: non-equilibrium dynamics of selection and adaptation.Q34949551
Inferring HIV Escape Rates from Multi-Locus Genotype DataQ34985572
Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodiesQ35116581
Dynamics of immunoglobulin sequence diversity in HIV-1 infected individualsQ35926722
Trade-offs in antibody repertoires to complex antigensQ35926729
The challenges of modelling antibody repertoire dynamics in HIV infectionQ35926734
Competitive exclusion by autologous antibodies can prevent broad HIV-1 antibodies from arisingQ36079024
Population genomics of intrapatient HIV-1 evolutionQ36479690
Germinal center B cells govern their own fate via antibody feedbackQ36694162
The paradox of alloreactivity and self MHC restriction: quantitative analysis and statisticsQ37229824
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithmQ37247974
Universality and predictability in molecular quantitative genetics.Q38167547
Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity MaturationQ38988188
Manipulating the selection forces during affinity maturation to generate cross-reactive HIV antibodiesQ42170932
Simulation of B cell affinity maturation explains enhanced antibody cross-reactivity induced by the polyvalent malaria vaccine AMA1.Q42795407
HIV: Roadmaps to a vaccineQ43534081
Time-shift experiments and patterns of adaptation across time and spaceQ44052146
Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginningQ46683819
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P921main subjectco-evolutionQ208841
P304page(s)e1006171
P577publication date2016-07-21
P1433published inPLOS GeneticsQ1893441
P1476titleHost-Pathogen Coevolution and the Emergence of Broadly Neutralizing Antibodies in Chronic Infections
P478volume12

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cites work (P2860)
Q50046798A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy.
Q92827369Fierce Selection and Interference in B-Cell Repertoire Response to Chronic HIV-1
Q92970064Modeling the immune response to HIV infection
Q92290575Multi-Lineage Evolution in Viral Populations Driven by Host Immune Systems
Q36263769Optimal Sequential Immunization Can Focus Antibody Responses against Diversity Loss and Distraction
Q54295384Predicting evolution.
Q89766835The size of the immune repertoire of bacteria
Q40153743What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Lessons from the Antibody Response to HIV-1.

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