Early neural crest induction requires an initial inhibition of Wnt signals.

scientific article

Early neural crest induction requires an initial inhibition of Wnt signals. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YDBIO.2012.02.029
P932PMC publication ID3657187
P698PubMed publication ID22394485
P5875ResearchGate publication ID221681416

P50authorRoberto MayorQ37838827
Benjamin SteventonQ60058064
P2093author name stringBen Steventon
P2860cites workIntegrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signalQ24301688
The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signalsQ24645277
Dickkopf-1 is a member of a new family of secreted proteins and functions in head inductionQ29616164
Appendix G: In Situ Hybridization: An Improved Whole-Mount Method for Xenopus EmbryosQ29620084
To proliferate or to die: role of Id3 in cell cycle progression and survival of neural crest progenitorsQ30448186
Xenopus crescent encoding a Frizzled-like domain is expressed in the Spemann organizer and pronephrosQ30911873
The Wnt/beta-catenin pathway posteriorizes neural tissue in Xenopus by an indirect mechanism requiring FGF signallingQ32057810
Early development of the central and peripheral nervous systems is coordinated by Wnt and BMP signalsQ33320527
Regulation of dorsal fate in the neuraxis by Wnt-1 and Wnt-3aQ33721756
Fgf8a induces neural crest indirectly through the activation of Wnt8 in the paraxial mesodermQ33922679
Goosecoid promotes head organizer activity by direct repression of Xwnt8 in Spemann's organizerQ34088948
Regulation of Msx genes by a Bmp gradient is essential for neural crest specificationQ34277895
Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer.Q34392431
Xenopus Id3 is required downstream of Myc for the formation of multipotent neural crest progenitor cells.Q34403655
Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1.Q34437048
Induction of neural crest in Xenopus by transcription factor AP2alphaQ34470119
Reiterative AP2a activity controls sequential steps in the neural crest gene regulatory networkQ34471732
Intracellular BMP signaling regulation in vertebrates: pathway or network?Q34488819
Neural fold formation at newly created boundaries between neural plate and epidermis in the axolotlQ34522031
Census of vertebrate Wnt genes: isolation and developmental expression of Xenopus Wnt2, Wnt3, Wnt9a, Wnt9b, Wnt10a, and Wnt16.Q34619425
FGF/MAPK signaling is required in the gastrula epiblast for avian neural crest inductionQ35624839
Opposing FGF and retinoid pathways: a signalling switch that controls differentiation and patterning onset in the extending vertebrate body axisQ35845613
Dorsal-ventral patterning and neural induction in Xenopus embryosQ35912796
Translation of mRNA injected into Xenopus oocytes is specifically inhibited by antisense RNA.Q36212817
Notch in the pathway: the roles of Notch signaling in neural crest development.Q36213083
Xenopus Zic3, a primary regulator both in neural and neural crest developmentQ36632950
Assembling neural crest regulatory circuits into a gene regulatory network.Q37540194
Neural crest determination by co-activation of Pax3 and Zic1 genes in Xenopus ectodermQ38327715
Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction.Q38330996
Conditional BMP inhibition in Xenopus reveals stage-specific roles for BMPs in neural and neural crest inductionQ38332721
Self-regulation of Stat3 activity coordinates cell-cycle progression and neural crest specificationQ38349452
lockjaw encodes a zebrafish tfap2a required for early neural crest development.Q38349455
The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest inductionQ38350690
Sox10 is required for the early development of the prospective neural crest in Xenopus embryos.Q38352189
Reiterated Wnt signaling during zebrafish neural crest developmentQ38518210
Zebrafish wnt8 encodes two wnt8 proteins on a bicistronic transcript and is required for mesoderm and neurectoderm patterning.Q38523908
Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of XenopusQ38533172
Dlx proteins position the neural plate border and determine adjacent cell fatesQ39517208
Embryonic induction--molecular prospects.Q39669488
Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural inductionQ40385522
Neural crest induction by paraxial mesoderm in Xenopus embryos requires FGF signals.Q40584140
Expression of Pax-3 in the lateral neural plate is dependent on a Wnt-mediated signal from posterior nonaxial mesodermQ41683443
Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizerQ41842388
Xmsx-1 modifies mesodermal tissue pattern along dorsoventral axis in Xenopus laevis embryoQ41927025
Xiro, a Xenopus homolog of the Drosophila Iroquois complex genes, controls development at the neural plateQ41976395
Differential requirements of BMP and Wnt signalling during gastrulation and neurulation define two steps in neural crest inductionQ42067316
Amphioxus and lamprey AP-2 genes: implications for neural crest evolution and migration patterns.Q42527237
Xenopus Distal-less related homeobox genes are expressed in the developing forebrain and are induced by planar signals.Q42601673
The status of Wnt signalling regulates neural and epidermal fates in the chick embryoQ43611057
The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrainQ43786017
Posteriorization by FGF, Wnt, and retinoic acid is required for neural crest inductionQ43849682
Zygotic Wnt activity is required for Brachyury expression in the early Xenopus laevis embryoQ44150973
Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extensionQ44607276
Noradrenergic neurons in the zebrafish hindbrain are induced by retinoic acid and require tfap2a for expression of the neurotransmitter phenotypeQ44610891
Interplay between Notch signaling and the homeoprotein Xiro1 is required for neural crest induction in Xenopus embryos.Q44697354
Multiple points of interaction between retinoic acid and FGF signaling during embryonic axis formation.Q44884937
Origins of the avian neural crest: the role of neural plate-epidermal interactions.Q45950522
Ectodermal Wnt function as a neural crest inducer.Q46043546
Neural crest induction in Xenopus: evidence for a two-signal model.Q46365285
The Xenopus homolog of Drosophila Suppressor of Hairless mediates Notch signaling during primary neurogenesisQ46616095
Role of BMP signaling and the homeoprotein Iroquois in the specification of the cranial placodal fieldQ47073604
Delta/Notch signaling promotes formation of zebrafish neural crest by repressing Neurogenin 1 functionQ47073883
Delta signaling mediates segregation of neural crest and spinal sensory neurons from zebrafish lateral neural plateQ47073960
Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genesQ47073994
The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradientQ47862681
Xenopus Zic family and its role in neural and neural crest developmentQ48022555
Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8.Q48052411
Notch controls proliferation and differentiation of stem cells in a dose-dependent mannerQ48536404
Neural crests are actively precluded from the anterior neural fold by a novel inhibitory mechanism dependent on Dickkopf1 secreted by the prechordal mesoderm.Q51979531
Wnt signals provide a timing mechanism for the FGF-retinoid differentiation switch during vertebrate body axis extension.Q51985699
Xenopus hairy2 functions in neural crest formation by maintaining cells in a mitotic and undifferentiated state.Q51988923
Identification of neural crest competence territory: role of Wnt signaling.Q52095654
Deltex/Dtx mediates NOTCH signaling in regulation of Bmp4 expression in cranial neural crest formation during avian development.Q52103630
Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest.Q52111064
Bimodal functions of Notch-mediated signaling are involved in neural crest formation during avian ectoderm development.Q52123444
Distinct roles for Distal-less genes Dlx3 and Dlx5 in regulating ectodermal development in Xenopus.Q52128600
A role for frizzled 3 in neural crest development.Q52128900
Requirement of FoxD3-class signaling for neural crest determination in Xenopus.Q52131385
Overexpression of the transcriptional repressor FoxD3 prevents neural crest formation in Xenopus embryos.Q52135855
A novel member of the Xenopus Zic family, Zic5, mediates neural crest development.Q52144447
Relationship between gene expression domains of Xsnail, Xslug, and Xtwist and cell movement in the prospective neural crest of Xenopus.Q52166292
Establishment and maintenance of the border of the neural plate in the chick: involvement of FGF and BMP activity.Q52176692
Role of FGF and noggin in neural crest induction.Q52192891
Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4.Q52193245
Expression of Pax-3 is initiated in the early neural plate by posteriorizing signals produced by the organizer and by posterior non-axial mesoderm.Q52194790
A graded response to BMP-4 spatially coordinates patterning of the mesoderm and ectoderm in the zebrafish.Q52195885
Neural crest formation in Xenopus laevis: mechanisms of Xslug induction.Q52200484
Induction of the prospective neural crest of Xenopus.Q52209849
Transcriptional regulation of a Xenopus embryonic epidermal keratin gene.Q52246296
Hairy2–Id3 interactions play an essential role in Xenopus neural crest progenitor specificationQ63255985
Early requirement of the transcriptional activator Sox9 for neural crest specification in Xenopus.Q64983202
Requirement of Sox2-mediated signaling for differentiation of early Xenopus neuroectodermQ73386441
Paraxial-fated mesoderm is required for neural crest induction in Xenopus embryosQ74213802
Neural induction in Xenopus requires inhibition of Wnt-beta-catenin signalingQ80033357
Hairy2 functions through both DNA-binding and non DNA-binding mechanisms at the neural plate border in XenopusQ81797403
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)196-207
P577publication date2012-02-25
P1433published inDevelopmental BiologyQ3025402
P1476titleEarly neural crest induction requires an initial inhibition of Wnt signals
P478volume365

Reverse relations

cites work (P2860)
Q41946331A gene network that coordinates preplacodal competence and neural crest specification in zebrafish
Q46523851A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates
Q52718320An atlas of Wnt activity during embryogenesis in Xenopus tropicalis.
Q33818173BMP, Wnt and FGF signals are integrated through evolutionarily conserved enhancers to achieve robust expression of Pax3 and Zic genes at the zebrafish neural plate border
Q27333540Cadherin-11 mediates contact inhibition of locomotion during Xenopus neural crest cell migration
Q35896949Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development
Q59830490Draxin acts as a molecular rheostat of canonical Wnt signaling to control cranial neural crest EMT
Q48184435Functional analysis of Hairy genes in Xenopus neural crest initial specification and cell migration.
Q64886689Intracellular attenuation of BMP signaling via CKIP-1/Smurf1 is essential during neural crest induction.
Q38313298Loss of Xenopus cadherin-11 leads to increased Wnt/β-catenin signaling and up-regulation of target genes c-myc and cyclin D1 in neural crest
Q37507635Multiple developmental mechanisms regulate species-specific jaw size.
Q26775970Neural crest: The fourth germ layer
Q98771678Neurogenesis From Neural Crest Cells: Molecular Mechanisms in the Formation of Cranial Nerves and Ganglia
Q50420114On the nature and function of organizers.
Q33967288PleiotRHOpic: Rho pathways are essential for all stages of Neural Crest development
Q39205991Signaling pathways and tissue interactions in neural plate border formation
Q27014510Signaling pathways regulating ectodermal cell fate choices
Q57294138The Ric-8A/Gα13/FAK signaling cascade controls focal adhesion formation during neural crest cell migration
Q88933916The neural border: Induction, specification and maturation of the territory that generates neural crest cells
Q38025839The peripheral sensory nervous system in the vertebrate head: a gene regulatory perspective
Q38874087Wnt/β-catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration

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